Titlebook: Wilson’s Disease; A Clinician’s Guide George J. Brewer Book 2001 Kluwer Academic Publishers 2001 Parkinson.biology.cognition.gastroenterol

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History, Important Milestones, and the Future,tant historical milestones. We will then end with a section on what I consider to be the most important future challenges and needs in Wilson’s disease, primarily with an eye toward improving patient recognition, diagnosis, and management.

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Initial Treatment of Patients Who Present with Liver Disease,“maintenance treatment” phase (discussed in Chapter 8). The length of the initial treatment period depends upon the drug being used. With zinc therapy alone, it may be as long as six months. With trientine or penicillamine used individually for the initial treatment of hepatic disease, it is about four months.

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Therapy of the Presymptomatic, the Pediatric, and the Pregnant Patient,the detection of cirrhosis during surgery or by some type of scan. It should be made clear that the patients under discussion are not completely normal. Invariably, they will have some underlying liver disease as a result of copper toxicity. However, the main point is that the patient has not yet presented clinically.

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l most likely see some Wilson‘s disease patientsduring their careers. See them - yes. Recognize and diagnosethem - maybe. If you are in one of these specialties, and apatient with tremor, hepatitis, cirrhosis, apparent Parkinsonism, ormood disorder, is referred to you, will you appropriately recogni

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,Description of the Anticopper Drugs Which are Used in Wilson’s Disease Therapy,chapter on overview of management in order to become familiar with various aspects of anticopper treatment and management. They can then turn to the chapter on managing their specific type of patient (one of Chapters 6–9).