Titlebook: Mechanisms of Drug Resistance in Cancer Therapy; Mario Mandalà,Emanuela Romano Book 2018 Springer Nature Switzerland AG 2018 Drug resistan

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Plasticity of Resistance and Sensitivity to Anti-Epidermal Growth Factor Receptor Inhibitors in Mets are rarer in this disease. Even though some of these molecular abnormalities make genes acting as drivers of cancer progression, translation of this recognition for therapeutic purposes is still limited, encompassing only as standard of care the exclusion of .-mutated cancers for better selecting

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Mechanism of Resistance in Gastrointestinal Stromal Tumors, in which the interaction between the drug and the receptor happens. Other mechanisms causing drug resistance have been investigated, indicating that many aspects need to be still explicated and fully understood in order to define a strategy able to fight definitively GIST growth.

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Mechanisms of Resistance in Multiple Myeloma,allenge our current understanding of treatment responses. Thirdly, the success of MM “novel agents” provides exemplary evidence for the impact of therapies that target the immune and non-immune microenvironment. Fourthly, the rapid pace of drug approvals for MM creates an impetus for development of

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e same approach is used to design clamps and limiting circuits which improve the performance of the amplifier outside of its linear operating region, such as slew rate enhancement, output short circuit current limitation, and input overload recovery.978-1-4419-5437-4978-1-4020-2517-4Series ISSN 0893-3405

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Benedetta Colmegna,Lavinia Morosi,Maurizio D’Incalcie same approach is used to design clamps and limiting circuits which improve the performance of the amplifier outside of its linear operating region, such as slew rate enhancement, output short circuit current limitation, and input overload recovery.978-1-4419-5437-4978-1-4020-2517-4Series ISSN 0893-3405

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Diego O. Croci,Santiago P. Mendez-Huergo,Juan P. Cerliani,Gabriel A. Rabinoviche same approach is used to design clamps and limiting circuits which improve the performance of the amplifier outside of its linear operating region, such as slew rate enhancement, output short circuit current limitation, and input overload recovery.978-1-4419-5437-4978-1-4020-2517-4Series ISSN 0893-3405

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