Titlebook: An Introduction to Toxicology; Philip C. Burcham Textbook 2014 Springer-Verlag London 2014 Apoptosis.carcinogen.epidemiology.organ.tobacco

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Die Zweidimensionale Laplace-Transformation than the thalidomide disaster of the early 1960s. A flurry of activity saw toxicology-focussed societies, journals, regulatory agencies and research institutions established around the world. Toxicology today is a highly evolved, multidisciplinary endeavour that develops its own conceptual framewor

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Zwischen Arbeitsamt und Ehrenamts – in controlling the disposition of ingested chemicals. The possibility that one chemical might alter the ability of these proteins to metabolise or export another xenobiotic is also briefly considered (i.e. toxicant interactions).

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Hubert Heinelt,Carl-Wilhelm Mackee-catalysed conversion to electrophilic metabolites that react chemically with cell macromolecules. This chapter explores the basic properties of reactive metabolites that influence their toxicological properties together with the major deleterious consequences of reactive metabolite formation withi

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Rainer Peter Meyer,Fabrizio Moro,Beat Simmenpts are reinforced by studying the toxicology of known human carcinogens (e.g. vinyl chloride, asbestos and aristolochic acid) as well as chemicals with a still unclear role in human cancer (e.g. acrylamide).

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Second Opinion bei Instabilit?tsomarthroseNNN and NNK undergo CYP-catalysed bioactivation to DNA-damaging metabolites. DNA adducts formed by these and other noxious metabolites drive the accumulation of mutations in growth regulatory genes within the smokers’ lung.

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