Titlebook: Bilirubin: Jekyll and Hyde Pigment of Life; Pursuit of Its Struc David A. Lightner Book 2013 The Editor(s) (if applicable) and The Author(s

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https://doi.org/10.1007/978-3-662-42422-3In current times, the complete proof of structure of a natural product may take weeks to months, less often days, occasionally a year. Yet, before the advent of modern organic spectroscopy techniques and powerful isolation-purifi cation methods, structure proof tended to consume years, if not decades.

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https://doi.org/10.1007/978-3-662-42422-3Numerous passages from the German scientifi c literature and from Latin and French appear scattered throughout the text and are translated into English in the following. Errors of translation are entirely the author’s. Let the reader beware: a translation is typically less than the original; sometimes more.

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Introduction,Only two reviews treating bilirubin and other bile pigments have appeared in . The first, in volume III, 1939, under the title “Gallenfarbstoffe” (1) by ., a student of ., appeared three years prior to the published total synthesis of bilirubin.

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Early Scientific Investigations,Following ., the early investigators of medicinal chemistry were often largely trained as physicians who had gained a knowledge of the emerging field of chemistry, a field yet in its infancy.

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