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Titlebook: Vaccine Analysis: Strategies, Principles, and Control; Brian K. Nunnally,Vincent E. Turula,Robert D. Sitr Book 2015 Springer-Verlag Berlin

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書目名稱Vaccine Analysis: Strategies, Principles, and Control
編輯Brian K. Nunnally,Vincent E. Turula,Robert D. Sitr
視頻videohttp://file.papertrans.cn/981/980183/980183.mp4
概述Equips readers to handle the complex analysis of vaccines.Treats both research and application aspects.Describes analytical and quality control technologies.Includes supplementary material:
圖書封面Titlebook: Vaccine Analysis: Strategies, Principles, and Control;  Brian K. Nunnally,Vincent E. Turula,Robert D. Sitr Book 2015 Springer-Verlag Berlin
描述.This book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities..Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure..
出版日期Book 2015
關(guān)鍵詞Active pharmaceutical ingredient (API); Bacterial derived proteins; Biosafety; Effective immune respons
版次1
doihttps://doi.org/10.1007/978-3-662-45024-6
isbn_softcover978-3-662-52266-0
isbn_ebook978-3-662-45024-6
copyrightSpringer-Verlag Berlin Heidelberg 2015
The information of publication is updating

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Live Attenuated Viral Vaccines,major, Plotkin and Plotkin .). The word vaccine comes from the Latin “vaccinus” meaning “of cows”—an adjective joining variola (smallpox) and vaccinae to form cowpox (variola vaccinae, Jenner .; Riedel .) as distinct from the human disease (variola). Variola was easily transmitted, had high mortalit
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Inactivated Viral Vaccines,s relatively straightforward to achieve and there is an augmented safety profile as compared to their live counterparts. Today, there are six viral pathogens for which licensed inactivated vaccines are available with many more in development. Here, we describe the principles of viral inactivation an
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Role of Analytics in Viral Safety,thods differ in their detection principles. These facets may permit novel methods to emerge to supplement, refine, or replace the routine methods. We have suggested a framework for risk assessment to assure biosafety in vaccines and suggested quantitative modeling to help crystallize thinking about
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