標(biāo)題: Titlebook: DNA Methylation: Development, Genetic Disease and Cancer; Walter Doerfler,Petra B?hm Book 2006 The Editor(s) (if applicable) and The Autho [打印本頁(yè)] 作者: Daguerreotype 時(shí)間: 2025-3-21 16:30
書目名稱DNA Methylation: Development, Genetic Disease and Cancer影響因子(影響力)
書目名稱DNA Methylation: Development, Genetic Disease and Cancer影響因子(影響力)學(xué)科排名
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書目名稱DNA Methylation: Development, Genetic Disease and Cancer網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱DNA Methylation: Development, Genetic Disease and Cancer被引頻次
書目名稱DNA Methylation: Development, Genetic Disease and Cancer被引頻次學(xué)科排名
書目名稱DNA Methylation: Development, Genetic Disease and Cancer年度引用
書目名稱DNA Methylation: Development, Genetic Disease and Cancer年度引用學(xué)科排名
書目名稱DNA Methylation: Development, Genetic Disease and Cancer讀者反饋
書目名稱DNA Methylation: Development, Genetic Disease and Cancer讀者反饋學(xué)科排名
作者: 不連貫 時(shí)間: 2025-3-22 00:04 作者: Popcorn 時(shí)間: 2025-3-22 02:36 作者: intrigue 時(shí)間: 2025-3-22 06:26
Aria, acqua, terra e fuoco - Volume II. Primary epimutations often occur after fertilization and lead to somatic mosaicism. It has been estimated that the rate of primary epimutations is one or two orders of magnitude greater than somatic DNA mutation. Therefore, the contribution of epimutations to human disease is probably underestimated.作者: Missile 時(shí)間: 2025-3-22 11:59 作者: 感情脆弱 時(shí)間: 2025-3-22 16:14
Epimutations in Human Disease,. Primary epimutations often occur after fertilization and lead to somatic mosaicism. It has been estimated that the rate of primary epimutations is one or two orders of magnitude greater than somatic DNA mutation. Therefore, the contribution of epimutations to human disease is probably underestimated.作者: 感情脆弱 時(shí)間: 2025-3-22 19:30
Genome-wide Analysis of DNA Methylation Changes in Human Malignancies,et in clinical studies, it is of utmost importance to define potential target sequences that could be used as diagnostic or prognostic markers. We conclude the review by outlining possible scenarios that may explain tumor type-specific DNA methylation patterns described by assays evaluating genome-wide levels of DNA methylation.作者: debunk 時(shí)間: 2025-3-23 00:19 作者: savage 時(shí)間: 2025-3-23 03:48
Book 2006nting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems..作者: adequate-intake 時(shí)間: 2025-3-23 06:12 作者: Debark 時(shí)間: 2025-3-23 12:30
https://doi.org/10.1007/3-540-31181-5DNA; biology; cell; development; developmental biology; gene; gene expression; gene therapy; genes; genetics; 作者: 鬼魂 時(shí)間: 2025-3-23 17:08
978-3-642-06830-0The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE作者: 神圣不可 時(shí)間: 2025-3-23 19:54 作者: 字謎游戲 時(shí)間: 2025-3-23 23:11 作者: Epidural-Space 時(shí)間: 2025-3-24 05:56 作者: semiskilled 時(shí)間: 2025-3-24 09:03
Aria, acqua, terra e fuoco - Volume II our understanding of epigenetic regulation in the fruit fly .. In the past, DNA methylation research has primarily utilized mammalian model systems. However, several recent landmark discoveries have been made in other organisms. For example, the interaction between DNA methylation and histone methy作者: 放肆的你 時(shí)間: 2025-3-24 13:00
Aria, acqua, terra e fuoco - Volume IIl-heritable chromatin states. Inappropriate expression or repression of genes can change developmental trajectories and result in disease. Aberrant chromatin states leading to aberrant gene expression patterns (epimutations) have been detected in several recognizable syndromes as well as in cancer. 作者: 注意到 時(shí)間: 2025-3-24 17:37
Aria, acqua, terra e fuoco - Volume IINA sequence. Restricted expression of latent, episomal herpesvirus genomes is also due to epigenetic modifications. There is no virus production (lytic viral replication, associated with the expression of all viral genes) in tight latency. . experiments demonstrated that DNA methylation could influe作者: 傀儡 時(shí)間: 2025-3-24 20:15 作者: entrance 時(shí)間: 2025-3-24 23:17 作者: 1FAWN 時(shí)間: 2025-3-25 04:42 作者: Obscure 時(shí)間: 2025-3-25 11:00 作者: 集聚成團(tuán) 時(shí)間: 2025-3-25 12:29 作者: 泛濫 時(shí)間: 2025-3-25 15:54
Precipitation and Evapotranspiration represented by LINE-1, nonautonomous small interspersed nuclear elements (SINEs) are primarily represented by ALUs, and LTR retrotransposons by several families of human endogenous retroviruses (HERVs). The vast majority of LINE and HERV elements are densely methylated in normal somatic cells and c作者: 本能 時(shí)間: 2025-3-25 23:54 作者: bacteria 時(shí)間: 2025-3-26 01:43
Walter Doerfler,Petra B?hmIncludes supplementary material: 作者: Anthology 時(shí)間: 2025-3-26 06:38 作者: 怪物 時(shí)間: 2025-3-26 11:56
The Regulation of Chromatin and DNA-Methylation Patterns in Blood Cell Development,ial gene expression is also the basis for the alterations in the developmental potential of differentiating cells. However, the molecular details concerning how this is achieved are still poorly understood. The haematopoietic system has for many years served as an excellent model system to study how作者: Kaleidoscope 時(shí)間: 2025-3-26 15:15
Methylation Dynamics in the Early Mammalian Embryo: Implications of Genome Reprogramming Defects foevelopment. The paternal genome is actively demethylated within a few hours after fertilization in the mouse, rat, pig, bovine, and human zygote, whereas the maternal genome is passively demethylated by a replication-dependent mechanism after the two-cell embryo stage. These genome-wide demethylatio作者: curriculum 時(shí)間: 2025-3-26 16:58 作者: ferment 時(shí)間: 2025-3-26 21:33 作者: 諂媚于人 時(shí)間: 2025-3-27 03:36
Epigenotypes of Latent Herpesvirus Genomes,NA sequence. Restricted expression of latent, episomal herpesvirus genomes is also due to epigenetic modifications. There is no virus production (lytic viral replication, associated with the expression of all viral genes) in tight latency. . experiments demonstrated that DNA methylation could influe作者: 劇毒 時(shí)間: 2025-3-27 05:46 作者: 罐里有戒指 時(shí)間: 2025-3-27 09:56
MSL Proteins and the Regulation of Gene Expression,tion of gene expression by an epigenetic mechanism. Dosage compensation has evolved to balance the expression of sex-linked genes in males and females, which possess different numbers of sex chromosomes. However, the genetic sequence of the chromosomes is the same in both sexes. This mechanism there作者: Fallibility 時(shí)間: 2025-3-27 16:46
DNA Methylation Profiles of Female Steroid Hormone-Driven Human Malignancies,sociated with distinct tumorigenic pathways. These pathway-specific DNA methylation changes help define tumor-specific DNA methylation profiles that can be used to further our understanding of tumor development, as well as provide tools for molecular diagnosis and early detection of cancer. Female s作者: 侵害 時(shí)間: 2025-3-27 19:47
Genome-wide Analysis of DNA Methylation Changes in Human Malignancies, expression. DNA methylation patterns are heritable and can be passed on to the daughter cell. In this review, we briefly summarize our current knowledge on normal DNA methylation patterns and move on to discuss the current state of the field with respect to altered DNA methylation in cancer. We mak作者: Parley 時(shí)間: 2025-3-27 23:16
Decreased Fidelity in Replicating DNA Methylation Patterns in Cancer Cells Leads to Dense Methylatised fidelity in replicating methylation patters has been analyzed as an underlying mechanism. First we developed a method to analyze the number of errors in replicating CpG methylation patterns in a defined period. A single cell was expanded into 10. cells, and the number of errors during the cultur作者: 初學(xué)者 時(shí)間: 2025-3-28 03:42 作者: reserve 時(shí)間: 2025-3-28 10:07
Cancer-Linked DNA Hypomethylation and Its Relationship to Hypermethylation,. Both decreases and increases in DNA methylation are a frequent characteristic of a wide variety of cancers. There is often more hypomethylation than hypermethylation of DNAduring carcinogenesis, leading to a net decrease in the genomic 5-methylcytosine content. Although the exactmethylation change作者: 新星 時(shí)間: 2025-3-28 14:21 作者: 勉強(qiáng) 時(shí)間: 2025-3-28 15:54 作者: 消耗 時(shí)間: 2025-3-28 19:26
Epigenotypes of Latent Herpesvirus Genomes,ggesting that histone modifications may control HSV-1 latency in terminally differentiated, quiescent neurons. Epstein-Barr virus (EBV, a human γ-herpesvirus) is associated with a series of neoplasms. Latent, episomal EBV genomes are subject to host cell-dependent epigenetic modifications (DNA methy作者: Preserve 時(shí)間: 2025-3-29 02:40 作者: 表皮 時(shí)間: 2025-3-29 03:39
MSL Proteins and the Regulation of Gene Expression,me underlying themes; the molecular components that mediate dosage compensation in both include non-coding RNA molecules, which act as nucleation points for the compensation process. Both systems utilise chromatin-modifying enzymes to remodel large domains of a chromosome. This review will discuss t作者: Insatiable 時(shí)間: 2025-3-29 08:40
DNA Methylation Profiles of Female Steroid Hormone-Driven Human Malignancies,d not find evidence for global hormone-specific DNA methylation alterations, suggesting that female sex hormones may participate in different tumorigenic pathways that are associated with distinct DNA methylation-based molecular signatures. One such pathway may include . methylation in the context o作者: 歌唱隊(duì) 時(shí)間: 2025-3-29 12:08 作者: ORE 時(shí)間: 2025-3-29 17:23
Methylation of Endogenous Human Retroelements in Health and Disease,egions, to separate domains and functional regions within one chromatin domain, to suppress transcriptional noise, and to regulate transcript stability. Retroelements, particularly ALUs, may also fulfill physiological roles during responses to stress and infections. Reactivation and hypomethylation 作者: 不能強(qiáng)迫我 時(shí)間: 2025-3-29 21:26
Cancer-Linked DNA Hypomethylation and Its Relationship to Hypermethylation, exhibit cancer-associated hypomethylation. However, one of these repeated sequences (NBL2) displayed predominant increases in methylation in some ovarian carcinomas and Wilms tumors and decreases in others. Furthermore, decreases and increases in CpG methylation can be interspersed within a small s
