標(biāo)題: Titlebook: Voltage-gated Sodium Channels: Structure, Function and Channelopathies; Mohamed Chahine Book 2018 Springer International Publishing AG, pa [打印本頁(yè)] 作者: DEBUT 時(shí)間: 2025-3-21 16:22
書目名稱Voltage-gated Sodium Channels: Structure, Function and Channelopathies影響因子(影響力)
書目名稱Voltage-gated Sodium Channels: Structure, Function and Channelopathies影響因子(影響力)學(xué)科排名
書目名稱Voltage-gated Sodium Channels: Structure, Function and Channelopathies網(wǎng)絡(luò)公開(kāi)度
書目名稱Voltage-gated Sodium Channels: Structure, Function and Channelopathies網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書目名稱Voltage-gated Sodium Channels: Structure, Function and Channelopathies被引頻次
書目名稱Voltage-gated Sodium Channels: Structure, Function and Channelopathies被引頻次學(xué)科排名
書目名稱Voltage-gated Sodium Channels: Structure, Function and Channelopathies年度引用
書目名稱Voltage-gated Sodium Channels: Structure, Function and Channelopathies年度引用學(xué)科排名
書目名稱Voltage-gated Sodium Channels: Structure, Function and Channelopathies讀者反饋
書目名稱Voltage-gated Sodium Channels: Structure, Function and Channelopathies讀者反饋學(xué)科排名
作者: Unsaturated-Fat 時(shí)間: 2025-3-21 20:48 作者: synovitis 時(shí)間: 2025-3-22 03:51 作者: 擺動(dòng) 時(shí)間: 2025-3-22 04:32 作者: Accomplish 時(shí)間: 2025-3-22 10:59 作者: inferno 時(shí)間: 2025-3-22 15:14
Zifan Pei,Yanling Pan,Theodore R. Cumminshe acetabular notch. Another approach, using CT, involves addition of scans, one at the maximal diameter of the femoral head and the other at the top of the femoral head. This method is also approximate, as it only evaluates the situation in two planes. The only accurate method is assessment of the 作者: aneurysm 時(shí)間: 2025-3-22 20:29 作者: DEFER 時(shí)間: 2025-3-23 00:33 作者: Germinate 時(shí)間: 2025-3-23 04:48
Ademuyiwa S. Aromolaran,Mohamed Chahine,Mohamed Boutjdirnoch ein sehr gutes Auto für den allt?glichen Transport von Personen ist, kann man nicht den genannten Rechner für jedes und alles mit Erfolg einsetzen. Je nach Aufgabenstellung mu? man die Merkmale unterschiedlich bewerten. Für jemanden, der nur fünf Kilometer t?glich zur Arbeit hat, ist Benzinverb作者: yohimbine 時(shí)間: 2025-3-23 07:51
Yonghua Ji and appreciation of the students. Based on students’ responses to a questionnaire and observations of the tool in use, we investigated whether DYNAMO succeeded in engaging students and what factors stimulated/hampered this engagement. Despite the prototype nature of the system, students were notice作者: 昆蟲 時(shí)間: 2025-3-23 13:31 作者: faculty 時(shí)間: 2025-3-23 16:20 作者: PURG 時(shí)間: 2025-3-23 18:47 作者: 復(fù)習(xí) 時(shí)間: 2025-3-24 01:42 作者: homocysteine 時(shí)間: 2025-3-24 02:45 作者: insightful 時(shí)間: 2025-3-24 08:28 作者: Ballerina 時(shí)間: 2025-3-24 11:47 作者: glans-penis 時(shí)間: 2025-3-24 18:48 作者: 可憎 時(shí)間: 2025-3-24 20:29 作者: corpus-callosum 時(shí)間: 2025-3-25 02:27
Regulation of Cardiac Voltage-Gated Sodium Channel by Kinases: Roles of Protein Kinases A and Cthe functional expression (localization, trafficking and gating) of Na.1.5 may be under modulation by post-translational modifications that are associated with phosphorylation. We review here the molecular basis of cardiac Na channel regulation by kinases (PKA and PKC) and the resulting functional c作者: modifier 時(shí)間: 2025-3-25 04:26
Mechanisms of Drug Binding to Voltage-Gated Sodium Channelsing, and cell-surface expression of the channels. The permeation pore of Na. channels is divided in two parts: the outer mouth of the pore is the site of the ion selectivity filter, while the inner cytoplasmic pore serves as the channel activation gate. The cytoplasmic lining of the permeation pore 作者: pacifist 時(shí)間: 2025-3-25 10:17
Effects of Benzothiazolamines on Voltage-Gated Sodium Channelsropensity to prolong the cardiac QT interval, due to hERG K. channel block. Lubeluzole very potently inhibits Na. channels in a voltage- and use-dependent manner, due to its great preferential affinity for inactivated channels and the presence of a protonable amine group. Patch-clamp experiments sug作者: chemoprevention 時(shí)間: 2025-3-25 12:56
Selective Ligands and Drug Discovery Targeting the Voltage-Gated Sodium Channel Nav1.7f Nav1.7-selective inhibitors: the extracellular vestibule of the pore, the extracellular loops of voltage-sensor domain II (VSD2), and the extracellular loops of voltage-sensor domain IV (VSD4). Notably, these three receptor sites on Nav1.7 can all be defined as extracellular druggable sites, sugge作者: 把手 時(shí)間: 2025-3-25 15:51
Cardiac Arrhythmias Related to Sodium Channel Dysfunctionses, such as dilated cardiomyopathy. The same rare variants in . or related genes may present with different clinical phenotypes in different individuals and sometimes in members of the same family. Genetic background and epigenetic and environmental factors contribute to the expression of these ove作者: fulmination 時(shí)間: 2025-3-25 21:21
d are identified in this introduction and are given attention throughout the text. The first and most classical approach uses a minimal set of Lagrangian genera978-3-642-52467-7978-3-642-52465-3Series ISSN 0258-1248 作者: Genistein 時(shí)間: 2025-3-26 01:29
Steven Molinarolo,Daniele Granata,Vincenzo Carnevale,Christopher A. Ahern作者: 仔細(xì)檢查 時(shí)間: 2025-3-26 04:22
Alessandro Farinato,Concetta Altamura,Jean-Fran?ois Desaphy作者: Customary 時(shí)間: 2025-3-26 08:52
Voltage-gated Sodium Channels: Structure, Function and Channelopathies作者: appall 時(shí)間: 2025-3-26 16:13 作者: Myelin 時(shí)間: 2025-3-26 18:50 作者: 使入迷 時(shí)間: 2025-3-27 01:02 作者: 服從 時(shí)間: 2025-3-27 02:36 作者: 挑剔為人 時(shí)間: 2025-3-27 09:07
Elise Balse,Catherine Eichelt extends from the diaphragm superiorly to the level of the pelvic viscera inferiorly. On transverse sections it usually has a C-shape with the convexity in the midline projecting anteriorly. This shape is the result of the relationship of the abdominal walls to one another as they enclose the lordo作者: 澄清 時(shí)間: 2025-3-27 11:58 作者: 開(kāi)始發(fā)作 時(shí)間: 2025-3-27 14:06 作者: 楓樹(shù) 時(shí)間: 2025-3-27 19:49
Colin H. Peters,Mohammad-Reza Ghovanloo,Cynthia Gershome,Peter C. Rubenng in das Computerwesen von gr??ter Wichtigkeit. K. W. Blutke hat hier die Probleme der Hardware und Software in geschickter und praxisnaher Weise darge- stellt, so da? sie jeder Interessierte - auch ohne spezielle Vorkenntniss- verstehen kann. Der DarsteUungsstil zeigt einerseits gründliche Sachken作者: CODA 時(shí)間: 2025-3-27 22:33
Ademuyiwa S. Aromolaran,Mohamed Chahine,Mohamed Boutjdirnen, z. B. Multiplikationen ausführen kann. Der Autor selbst hatte vor geraumer Zeit die Aufgabe einen Rechner vorzustellen, der in der Industrie zum automatischen Testen eingesetzt wird. Wie üblich, ging alsbald im Auditorium die Frage herum, wie schnell denn die Kiste nun sei. Nach dem Prinzip ?We作者: SOB 時(shí)間: 2025-3-28 05:37
tion of Mechanical System Dynamics" held in Iowa City, Iowa, 1-12 August, 1983. Lectures were presented by free world leaders in the field of machine dynamics and optimization. Participants in the Institute were specialists from throughout NATO, many of whom presented contributed papers during the I作者: 豐富 時(shí)間: 2025-3-28 07:22 作者: 埋葬 時(shí)間: 2025-3-28 11:36
M. E. O’Leary,M. Chahine discretization process is very long, tedious and error prone as for every triangle the vertices must be numbered according certain rules, their coordinates measured and punched on cards and the incidences with neighboring vertices listed, and there could be some hundreds or even thousand of triangl作者: syring 時(shí)間: 2025-3-28 15:35
Boris S. Zhorov must construct at least a crude model of the design process. The problem, however, is that design processes are quite different from one another, depending on the product (a bicycle versus a nuclear power plant), on the company’s size and organization (a large architectural engineering firm versus 作者: 同來(lái)核對(duì) 時(shí)間: 2025-3-28 20:06
Jian Payandeh,David H. Hackost of the Book In Chapter 2 we present briefly the history of CAD. The main components of CAD systems are identified, and their principal functions described. Economi- cal and interdisciplinary aspects are discussed. Chapter 3 starts with a systems analysis of the design process. The notion of a proc作者: 逃避系列單詞 時(shí)間: 2025-3-29 01:26
Stephen C. Cannonforced material, and a similar two-dimensional scheme to simulate the fibre reorientation which would occur in other flow geometries. These geometries include a planar channel, a step and a contraction. The planar contraction is used primarily to test the numerical code. The material is modelled as 作者: 違抗 時(shí)間: 2025-3-29 03:20 作者: Landlocked 時(shí)間: 2025-3-29 10:06 作者: Angioplasty 時(shí)間: 2025-3-29 15:10
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/v/image/984219.jpg作者: ingrate 時(shí)間: 2025-3-29 19:05 作者: 平息 時(shí)間: 2025-3-29 20:42 作者: 凈禮 時(shí)間: 2025-3-30 02:15 作者: Parley 時(shí)間: 2025-3-30 08:06
Book 2018ases. Among the topics discussed are the structural basis of Na+ channel function, methodological advances in the study of Na+ channels, their pathophysiology and drugs and toxins interactions with these channels and their associated channelopathies..作者: 朝圣者 時(shí)間: 2025-3-30 08:35 作者: 調(diào)色板 時(shí)間: 2025-3-30 12:32
Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspectiveion and its transmission from one location in the nervous system to another. In this review, we explore and compare structural and functional data from prokaryotic and eukaryotic channels to infer the effects of evolution on sodium channel structure and function.作者: Gleason-score 時(shí)間: 2025-3-30 16:49
Sodium Channel Traffickingquality control could lead to the retention of functional VGSC and is therefore the target of different pharmacological approaches. The present chapter gives an overview of the current understanding of the facets of VGSC life cycle in the context of both cardiac and neuronal cell types.作者: Meager 時(shí)間: 2025-3-30 21:41 作者: 排斥 時(shí)間: 2025-3-31 00:54
Structural Models of Ligand-Bound Sodium Channelsm channelopathies. Further summarized are sodium channel models with tetrodotoxin, mu-conotoxins, batrachotoxin, scorpion toxins, and insecticides. Possible involvement of sodium ions in the action of some ligands is discussed.作者: 正面 時(shí)間: 2025-3-31 08:51
Sodium Channelopathies of Skeletal Musclesis, congenital myasthenia, and congenital myopathy with hypotonia. Mutation-specific alternations of Na.1.4 function explain the mechanistic basis for the diverse phenotypes and identify opportunities for strategic intervention to modify the burden of disease.作者: Antigen 時(shí)間: 2025-3-31 11:31
0171-2004 logical advances in the study of Na+ channels, their pathophysiology and drugs and toxins interactions with these channels and their associated channelopathies..978-3-030-07982-6978-3-319-90284-5Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: nautical 時(shí)間: 2025-3-31 17:08
The Cardiac Sodium Channel and Its Protein Partnersn into macromolecular complexes. The purpose of the present section is to provide an overview of the characterized partners of the main cardiac sodium channel, Na.1.5, involved in regulating the functional expression of this channel both in terms of trafficking and targeting into microdomains.作者: entail 時(shí)間: 2025-3-31 21:12
Evolutionary History of Voltage-Gated Sodium Channelsn. The cells then utilize this transmembrane Na. concentration gradient as a driving force to produce electrical signals, sometimes in the form of action potentials. The protein family comprising voltage-gated sodium channels (Na.s) is essential for such signaling and enables cells to change their s作者: Melanoma 時(shí)間: 2025-4-1 00:58 作者: implore 時(shí)間: 2025-4-1 03:31
Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspectivellowed by fast inactivation that terminates the sodium current. This ON-OFF behavior of voltage-gated sodium channels underlays the coding of information and its transmission from one location in the nervous system to another. In this review, we explore and compare structural and functional data fro
