標(biāo)題: Titlebook: Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease; J?rg Striessnig Book 2023 The Editor(s) (if applica [打印本頁(yè)] 作者: 畸齒矯正學(xué) 時(shí)間: 2025-3-21 16:32
書(shū)目名稱(chēng)Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease影響因子(影響力)
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書(shū)目名稱(chēng)Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease被引頻次
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書(shū)目名稱(chēng)Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease讀者反饋
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作者: 驕傲 時(shí)間: 2025-3-21 21:08 作者: 眉毛 時(shí)間: 2025-3-22 02:58
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/v/image/984218.jpg作者: 形容詞詞尾 時(shí)間: 2025-3-22 07:22 作者: 察覺(jué) 時(shí)間: 2025-3-22 10:56 作者: 抒情短詩(shī) 時(shí)間: 2025-3-22 15:55 作者: 連接 時(shí)間: 2025-3-22 19:00
ncology physician. Interestingly, the chemical identity of cisplatin was first established in the mid-19th century (and known as Peyrone’s chloride) and, were it not for the well-documented serendipitous observations of Barnett Rosenberg while performing experiments investigating the effects of elec作者: RENIN 時(shí)間: 2025-3-23 00:44 作者: 怕失去錢(qián) 時(shí)間: 2025-3-23 04:33
Miguel Martín-Aragón Baudel,Junyoung Hong,Johannes W. Hell,Madeline Nieves-Cintrón,Manuel F. Navedotoma multiforme, usually grows in the deep white matter of cerebrum and rapid invasion in multiple directions along the white matter has already occurred by the time of diagnosis. Infiltrated tumor cells into the surrounding brain tissue were observed at least 2 cm apart from the margin of the enhan作者: definition 時(shí)間: 2025-3-23 09:27 作者: 辭職 時(shí)間: 2025-3-23 11:09
Kelvin Wei Zhern Loh,Zhenyu Hu,Tuck Wah Soongf these mechanisms has provided the basis for rational approaches to overcoming or reversing drug resistance and thereby making cancer chemotherapy more effective. . studies with tumor cell lines carried out by Ling in the mid-1970’s suggested that prolonged exposure of the cells to one compound (e.作者: 指耕作 時(shí)間: 2025-3-23 14:57
the proper staging of patients have been developed at several centers, but these data and their implications for staging and management have not been universally accepted. Research at several institutions has indicated that a combined modality approach to some patients with early stage disease offe作者: 特別容易碎 時(shí)間: 2025-3-23 21:21 作者: LAVE 時(shí)間: 2025-3-23 22:33 作者: 冷漠 時(shí)間: 2025-3-24 03:36
- tinue to develop expertise in the detection and management of cardiac prob- we intensify efforts to improve survival in patients who at an lems and as earlier time might have succumbed to advanced disease and a fragile cardio- vascular system. With our aging population and the developing complexit作者: absolve 時(shí)間: 2025-3-24 06:31
Kevin G. Herold,John W. Hussey,Ivy E. Dickcancer aetiology. The predominant theory for the past 50 years has been that cancer is the result of cumulative mutations that alter specific locations in a cell’s DNA and which alter the proteins encoded by cancer-related genes. Susceptibility to mutation has been mainly researched with respect to 作者: 眼界 時(shí)間: 2025-3-24 14:24 作者: Catheter 時(shí)間: 2025-3-24 15:37
Elisabetta Indelicato,Sylvia Boeschment de s’assurer de la conformité des programmes départementaux au nouveau cahier des charges, afin d’obtenir une homogénéité du dispositif. Une évaluation des résultats, qui est indispensable, ne sera en effet possible que si les modalités retenues sont comparables..Le programme est ambitieux, mai作者: 不真 時(shí)間: 2025-3-24 20:03
Hoang An Dinh,Gabriel St?lting,Ute I. Scholl et 20 à 85 % de l’ensemble de ces patientes, en fonction du stade initial, de la biologie tumorale et du traitement récidiveront soit sous forme locale, soit sous forme métastatique. L’objet de cette présentation est de présenter quels sont les facteurs pronostiques indépendants et de les distingue作者: gonioscopy 時(shí)間: 2025-3-25 01:56 作者: 容易做 時(shí)間: 2025-3-25 05:28
0171-2004 Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation..978-3-031-38439-4978-3-031-38437-0Series ISSN 0171-2004 Series E-ISSN 1865-0325 作者: CUMB 時(shí)間: 2025-3-25 09:32 作者: Orchiectomy 時(shí)間: 2025-3-25 13:16
Ca,3.2 (,) in Primary Aldosteronismfied in familial hyperaldosteronism, whereas somatic mutations are a rare cause of aldosterone-producing adenomas. In this review, we summarize these findings, put them in perspective, and highlight missing knowledge.作者: 芳香一點(diǎn) 時(shí)間: 2025-3-25 16:31
Book 2023ffecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation..作者: 爆米花 時(shí)間: 2025-3-25 21:35
CaV1.1 Calcium Channel Signaling Complexes in Excitation–Contraction Coupling: Insights from Channelchannel (Ca.1.1), located in the sarcolemma and functioning as the voltage sensor of EC coupling, and the ryanodine receptor 1 (RyR1), located on the sarcoplasmic reticulum serving as the calcium release channel. To this day, the molecular mechanism by which these two ion channels are linked remains作者: Leisureliness 時(shí)間: 2025-3-26 01:13 作者: dainty 時(shí)間: 2025-3-26 05:17
Sympathetic Nervous System Regulation of Cardiac Calcium Channels rate of cardiac contraction are modulated by the sympathetic nervous system, mediated substantially by changes in intracellular calcium. Norepinephrine released from sympathetic neurons innervating the heart and epinephrine secreted by the adrenal chromaffin cells bind to β-adrenergic receptors on 作者: 縮短 時(shí)間: 2025-3-26 11:20
Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: pertension, atherosclerosis, myocardial infarction, and heart failure. But, a few controversies still remain. Therefore, exploring new ways to modulate Ca.1.2 channel activity will augment the arsenal of Ca.1.2 channel-based therapeutics for treatment of cardiovascular diseases. Here, we will mainly作者: Substitution 時(shí)間: 2025-3-26 15:48 作者: 性冷淡 時(shí)間: 2025-3-26 17:00
Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitorsnd physiological functions including neurotransmission, muscle contraction, and regulation of gene expression. The impressive ability of a singular signal, Ca. influx, to have such a plethora of functional outcomes is enabled by: molecular diversity of HVGCC pore-forming α. and auxiliary subunits; o作者: 樹(shù)上結(jié)蜜糖 時(shí)間: 2025-3-27 00:06 作者: 低位的人或事 時(shí)間: 2025-3-27 01:38 作者: 節(jié)省 時(shí)間: 2025-3-27 06:48 作者: OTHER 時(shí)間: 2025-3-27 11:41
Ca,3.2 (,) in Primary Aldosteronisml of electrolyte homeostasis and blood pressure via the kidneys. The primary factors regulating aldosterone synthesis are the serum concentrations of angiotensin II and potassium. The T-type voltage-gated calcium channel Ca.3.2 (encoded by .) is an important component of electrical as well as intrac作者: 疏遠(yuǎn)天際 時(shí)間: 2025-3-27 14:20 作者: Galactogogue 時(shí)間: 2025-3-27 19:00 作者: 憤憤不平 時(shí)間: 2025-3-27 23:01
Book 2023ncepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory作者: GRAVE 時(shí)間: 2025-3-28 03:41 作者: 紀(jì)念 時(shí)間: 2025-3-28 06:47
Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: t failure through fine-tuning Ca.1.2 channel activity. Of current interest, we will also evaluate the implication of the role of Ca.1.2 channel in SARS-CoV-2 infection and the potential treatments of COVID-19-related cardiovascular symptoms.作者: Harrowing 時(shí)間: 2025-3-28 10:42 作者: BUCK 時(shí)間: 2025-3-28 14:42 作者: DAMP 時(shí)間: 2025-3-28 20:44 作者: 創(chuàng)新 時(shí)間: 2025-3-28 23:39
The Role of Striatal Cav1.3 Calcium Channels in Therapeutics for Parkinson’s Diseasepopulation increases (Dorsey et al. Neurology 68:384–386, 2007). The daunting personal and socioeconomic burden has pressed scientists and clinicians to find improved symptomatic treatment options devoid side-effect liability and meaningful disease-modifying therapies. Federal and private sources ha作者: NATTY 時(shí)間: 2025-3-29 04:53
Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitorsng the scope of functional consequences of Ca. influx through them, and is also important for realizing their full potential as therapeutic targets. In this review, we discuss the gaps in the current landscape of small-molecule HVGCC blockers and how these may be addressed with designer genetically-作者: 前兆 時(shí)間: 2025-3-29 10:55 作者: 邪惡的你 時(shí)間: 2025-3-29 15:12 作者: 螢火蟲(chóng) 時(shí)間: 2025-3-29 15:35 作者: ESO 時(shí)間: 2025-3-29 22:21 作者: 啞劇 時(shí)間: 2025-3-30 00:29
