標(biāo)題: Titlebook: Vectors as Tools for the Study of Normal and Abnormal Growth and Differentiation; Heinz Lother,Rudolf Dernick,Wolfram Ostertag Book 1989 S [打印本頁(yè)] 作者: 乳缽 時(shí)間: 2025-3-21 16:46
書(shū)目名稱(chēng)Vectors as Tools for the Study of Normal and Abnormal Growth and Differentiation影響因子(影響力)
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作者: Laconic 時(shí)間: 2025-3-21 21:50
J. F. Nicolas,C. Bonnerot,C. Kress,H. Jouin,P. Briand,G. Grimber,M. Verneten gereinigt worden. Dann wurden sie ausgekocht, geputzt, ge?lt, wenn n?tig, und in den Schrank gelegt. Vor einer Operation werden sie einfach 10 Minuten lang in Wasser gekocht, dem auf 1 1 etwa 1 E?l?ffel Soda zugesetzt ist. Nur die Spritzen, die für Injektionen benutzt werden, sterilisiert man am 作者: Cosmopolitan 時(shí)間: 2025-3-22 03:32 作者: 北極熊 時(shí)間: 2025-3-22 04:46 作者: 要塞 時(shí)間: 2025-3-22 09:35
Antonito Panganiban soll nicht vor Vollendung des 16. Lebensjahres eine Ehe eingehen. Diese Vorschrift (vgl für das frühere Recht § 1303 a. F. BGB, aufgehoben durch § 84 EheG von 1938, Aufhebung best?tigt durch § 78 des Ehegesetzes von 1946) gilt für den Mann auch im Falle der Vollj?hrigkeitserkl?rung (. S. 1937 Anm 3作者: 名詞 時(shí)間: 2025-3-22 13:14 作者: 意外 時(shí)間: 2025-3-22 20:13 作者: forecast 時(shí)間: 2025-3-22 21:53 作者: 牽索 時(shí)間: 2025-3-23 03:27
Petra Artelt,J?rg Bartsch,Hansj?rg Hauser,Manfred Wirthersuchung der Kollusionsproblematik. Zur Modellierung und Bewertung relativer Anreizschemata werden der durch den Prinzipal erzielbare Nutzen bei Incentivierung ohne eine relative Komponente sowie die Nutzen aller m?glicher Verhaltensweisen der Agenten berechnet. Diese Ergebnisse werden ben?tigt, um作者: Pedagogy 時(shí)間: 2025-3-23 09:06 作者: Expediency 時(shí)間: 2025-3-23 12:17 作者: 禮節(jié) 時(shí)間: 2025-3-23 14:17
Andreas Zimmer,Peter Grusssgesamt angelieferten Erz sind 53% Flu?eisenstein, 36% Roteisenstein und 11% Brauneisenstein. Der Anteil an Feinerz unter 25 mm betr?gt 32%. Zur Erreichung einer guten Gleichm??igkeit im M?ller und zur Anwendung der als vorteilhaft erkannten ?physikalischen M?lleraufgabe“ wurde mit der Errichtung de作者: Fortify 時(shí)間: 2025-3-23 20:06
J. F. Nicolas,C. Bonnerot,C. Kress,H. Jouin,P. Briand,G. Grimber,M. Vernetmirohre besser in 3proz. Karbols?ure ein oder macht sie durch eine rasche Desinfektion in Sublimat keimfrei. Doch sollen sie dann vor der Benutzung stets erst mit steriler physiologischer Kochsalzl?sung abgespült werden, was besonders auch für die Katheter gilt, weil Sublimat durch die Harnr?hrensch作者: 最有利 時(shí)間: 2025-3-23 22:35
Rudolf Jaenisch,Douglas Gray,Tetsuo Noda,Hans Weiherzuverl?ssiger gesch?tzt werden kann als bisher, und das dritte war, Einblick in die verwickelten Vorg?nge in Trocknungstrommeln (von denen die Erw?rmungstrommeln ein Sonderfall sind) zu gewinnen. Es zeigte sich, da? dieser Einblick nur ein ungef?hres Bild geben konnte, denn viele der Grundvorg?nge, 作者: 強(qiáng)制令 時(shí)間: 2025-3-24 03:24
Manuel Grez,Ercan Akgün,Frank Hilberg,Marion Ziegler,Wolfram Ostertagdschaft steht (§ 1 Abs II EheG von 1946 i.d.F. d. FamR?ndG vom 11. 8. 1961 Art 2 Zff la, BGBl I S. 1226), d. h. er mu? für vollj?hrig erkl?rt sein. Diese Vorschrift findet ihre Rechtfertigung in Gründen, die zwar mit der biologischen Verschiedenheit nichts zu tun haben, gleichwohl aber dem Art 3 GG 作者: FLAG 時(shí)間: 2025-3-24 06:58 作者: 迅速成長(zhǎng) 時(shí)間: 2025-3-24 13:10 作者: 劇本 時(shí)間: 2025-3-24 15:03
Maja A. Sommerfelt,Robin A. Weisser folgenden Untersuchung geschehen; sie befa?t sich nur mit den Grunds?tzen, die bei der Inventur des Vorratsverm?gens zu beachten sind. Das Problem der Vorratsinventur war für die Bilanzierungspraxis immer von besonderem Gewicht, weil die handelsrechtliche Forderung nach einer k?rperlichen Aufnahme des gesa978-3-663-00356-4978-3-663-02269-5作者: 鋼盔 時(shí)間: 2025-3-24 19:34 作者: N防腐劑 時(shí)間: 2025-3-25 01:48 作者: 攤位 時(shí)間: 2025-3-25 05:56 作者: dilute 時(shí)間: 2025-3-25 10:44 作者: 作嘔 時(shí)間: 2025-3-25 13:45 作者: 邊緣帶來(lái)墨水 時(shí)間: 2025-3-25 17:45
Cellular Target Sequences for Retrovirus Integration,The integrated proviral DNA always lacks the terminal 2 base pairs (bp) as compared to the unintegrated precursor molecule, and it is flanked by short direct repeats of 4–6 bp derived by duplication of cellular target DNA, the length of the duplicated sequence being characteristic of the virus. This作者: 精確 時(shí)間: 2025-3-25 22:19
Identification of Retroviral Sequences Involved in the Inactivation of the Viral Genome in Embryonae and induced to differentiate in a wide variety of cell types, including derivatives of the three germ layers (Pierce, 1967; Damjanov and Solter, 1974; Martin, 1975). Once injected into the mouse blastocyst, ES cells can participate in the development of all somatic and germ cells of the growing em作者: Albumin 時(shí)間: 2025-3-26 02:13
Retroviral Receptors and Interference on Human Cells,variety of distinct retroviral receptors expressed on human cells and to group viruses according to their receptor specificity. Two assay systems were employed which exploited the ability of these viruses to induce the formation of multinucleate syncytia and to interact with the unrelated rhabdoviru作者: obnoxious 時(shí)間: 2025-3-26 06:34 作者: FLINT 時(shí)間: 2025-3-26 11:06
Hemopoietic Regulation Assessed in Clonal Culture: A Brief Overview,erentiation (commitment) and a summary of the studies of the effects of the growth factors on the proliferation of progenitors..This work was supported by NIH grant DK32294 and the Veterans Administration.作者: Aqueous-Humor 時(shí)間: 2025-3-26 13:20 作者: 你敢命令 時(shí)間: 2025-3-26 17:00
C. Paul Daniel,I. L. O. Ponting,J. Hampson,T. M. Dexter作者: RENAL 時(shí)間: 2025-3-27 00:51
Vectors as Tools for the Study of Normal and Abnormal Growth and Differentiation作者: exhilaration 時(shí)間: 2025-3-27 03:29
978-3-642-74199-9Springer-Verlag Berlin Heidelberg 1989作者: 確認(rèn) 時(shí)間: 2025-3-27 06:40
Vectors as Tools for the Study of Normal and Abnormal Growth and Differentiation978-3-642-74197-5Series ISSN 1010-8793 作者: 樂(lè)器演奏者 時(shí)間: 2025-3-27 09:56
1010-8793 Overview: 978-3-642-74199-9978-3-642-74197-5Series ISSN 1010-8793 作者: 賄賂 時(shí)間: 2025-3-27 17:04
Why a Workshop on Vectors as Tools for the Study of Normal and Abnormal Growth and Differentiation This volume contains contributions from a workshop which was sponsored as a NATO Advanced Research Workshop. The workshop was also supported by two German funding agencies, the Deutsche Forschungsgemeinschaft and the Stiftung Volkswagenwerk.作者: 赤字 時(shí)間: 2025-3-27 18:56 作者: 任命 時(shí)間: 2025-3-27 22:10
Nato ASI Subseries H:http://image.papertrans.cn/v/image/980865.jpg作者: emission 時(shí)間: 2025-3-28 04:33
https://doi.org/10.1007/978-3-642-74197-5antibody; cell; cell differentiation; cytokine; cytokines; gene; gene expression; gene therapy; genetics; leu作者: BRIDE 時(shí)間: 2025-3-28 09:51
Using Embryonal Stem Cells to Introduce Mutations into the Mouse Germ Line,many passages the ability to colonise the germ line of chimaeric mice following microinjection into host blastocysts (Bradley et al., 1984). This makes possible a novel strategy for the introduction of predetermined genetic changes into the mouse germ line. Mutant ES cell lines are isolated by the t作者: PUT 時(shí)間: 2025-3-28 13:08
New Strategies in Developmental Biology: In vivo Mutagenesis as a Tool to Dissect Mammalian Developnt to test the, at that time controversial, hypothesis whether development is strictly mosaic and predetermined or whether it is influenced by its environment. Roux recognized that the natural laws underlying the formative processes of development could only be elicited and analyzed by experimentati作者: 攤位 時(shí)間: 2025-3-28 15:29
Visualization by nlsLacZ of Gene Activity During Mouse Embryogenesis,rulation. From these progenitors, many distinct cell types develop during the next few days. Their probable number is far greater than the number of described histological cell types. When the embryo progenitor cells are determined the genome has been epigenetically modified. Indeed, the male and fe作者: 大火 時(shí)間: 2025-3-28 20:17 作者: ALT 時(shí)間: 2025-3-29 02:17
Mutations in Transgenic Mice,r human hereditary diseases but also permits a systematic genetic dissection of the mammalian genome. In mammals, three approaches have been successful in inducing mutations (Gridley et al., 1987; Jaenisch, 1988): (i) infection of preimplantation mouse embryos with retroviruses, (ii) microinjection 作者: Silent-Ischemia 時(shí)間: 2025-3-29 05:55 作者: glucagon 時(shí)間: 2025-3-29 08:33
Cellular Target Sequences for Retrovirus Integration,d host cell. Although central to the retroviral life cycle and decisive for many of the biological and pathological consequences of a retrovirus infection, the molecular events involved in the integration process are only partly understood. Viral DNA synthesis by reverse transcription and the struct作者: Crayon 時(shí)間: 2025-3-29 14:15
Identification of Retroviral Sequences Involved in the Inactivation of the Viral Genome in Embryona viral genome to accommodate foreign DNA sequences combined with its ability to infect a wide variety of cells make retroviruses an attractive system for gene transfer. However, the use of retroviruses to introduce and express foreign genes in mouse preimplantation embryos has been hampered because 作者: 不幸的人 時(shí)間: 2025-3-29 17:50
Strand Switching During Retroviral Reverse Transcription,genome into a linear double stranded DNA copy. A principal area of research in our lab has centered on template switching during reverse transcription and the consequences of this translocation depending on whether switching occurs intermolecularly or intramolecularly. For these studies we have exam作者: 我邪惡 時(shí)間: 2025-3-29 23:07 作者: 卷發(fā) 時(shí)間: 2025-3-30 01:30 作者: 放大 時(shí)間: 2025-3-30 04:25
Cell Targeting by Recombinant Retroviruses Using Bi-Specific Antibody Complexes,d successfully to infect human cells with ecotropic murine retroviruses via the interaction with MHC class I and class II antigens. The sequential protocol we developed requires less stringent safety constraints than would handling of amphotropic virus stocks. Although its efficiency is still relati作者: SEVER 時(shí)間: 2025-3-30 11:10 作者: 清楚說(shuō)話(huà) 時(shí)間: 2025-3-30 15:15
New Retroviral Models for Gene Therapy: Swords into Plowshares,RB) gene in retinoblastoma and osteosarcoma tumor cells. In both cases, transgene expression was accompanied by phenotypic changes in the target cells and organ. Established 208F rat fibroblasts expressing the NGF transgene and secreting active NGF were able to bring about the protection of choliner作者: Urgency 時(shí)間: 2025-3-30 17:35
Hemopoietic Regulation Assessed in Clonal Culture: A Brief Overview,ty to proliferate and produce progenitors that are committed to differentiation in single lineages. Because of this dynamic nature of the hemopoietic system, studies of the regulatory mechanisms of the hemopoietic system have been carried out by using functional assays. Both the spleen colony assay 作者: accomplishment 時(shí)間: 2025-3-30 21:50
Haemopoietic Cells as Targets for Gene Transfer,itioned hosts. In addition, methods are available for the manipulation of blood-forming cells in vitro. For these reasons haemopoietic cells are potential targets for therapeutic gene transfer. While this goal remains to be achieved, genes have already been successfully transferred to cultured cells作者: 腫塊 時(shí)間: 2025-3-31 04:19
,Human β-Globin Expression in Murine Bone Marrow Transplant Recipients Reconstituted with Retroviralr novel therapies in human medicine. Fundamental to such therapeutic endeavours is the development of retroviral vectors for efficient infection of somatic cells and the regulated expression of the inserted gene. Here, we will describe the basic features of the retroviral mediated gene transfer syst作者: 蹣跚 時(shí)間: 2025-3-31 09:04 作者: 死貓他燒焦 時(shí)間: 2025-3-31 10:42
Using Embryonal Stem Cells to Introduce Mutations into the Mouse Germ Line,entified by test-breeding, and their progeny carry the mutation in all their cells. Here I review our work on the isolation of an ES cell line, its use to produce mice deficient in the enzyme HPRT, and recent experiments which demonstrate how the approach can be generalised to introduce other genetic changes into the mouse germ line.作者: 祝賀 時(shí)間: 2025-3-31 17:15 作者: 猛擊 時(shí)間: 2025-3-31 21:14
The Albino Perinatal Lethal Mutation: Identification of Affected mRNAs and Mapping of the Locus by f the normal gene product. In addition, as a prelude to cloning the perinatal survival locus, a long-range restriction map has been established onto which the extents of albino locus deletions are being placed.作者: Mangle 時(shí)間: 2025-4-1 00:58
Mutations in Transgenic Mice, have been induced using the different methods of generating transgenic mice. In this article we will summarize our studies on recessive virus-induced insertional mutations and on the induction of dominant lethal mutations by introducing mutant genes into the early embryo.作者: chalice 時(shí)間: 2025-4-1 04:15
Do Retroviruses Contribute to the Genesis of Intron-Less Pseudogenes?, cDNA genes are truncated at both the 5’ and the 3’ ends; they do not contain poly(A) sequences, and - in three cases investigated so far - are not flanked by direct repeats. Therefore, cDNA genes formed by retroviral proteins lack the typical hallmarks of naturally occurring intron-less pseudogenes.作者: 沒(méi)有希望 時(shí)間: 2025-4-1 08:51 作者: 有幫助 時(shí)間: 2025-4-1 12:38
Strand Switching During Retroviral Reverse Transcription, and the consequences of this translocation depending on whether switching occurs intermolecularly or intramolecularly. For these studies we have examined the process of nucleic acid replication in replication-competent avian reticuloendotheliosis viruses (REV).作者: 狗舍 時(shí)間: 2025-4-1 17:32
Cell Targeting by Recombinant Retroviruses Using Bi-Specific Antibody Complexes,tocol we developed requires less stringent safety constraints than would handling of amphotropic virus stocks. Although its efficiency is still relatively low, the method appears to be general and versatile enough to be adapted to other cell membrane markers.作者: 模仿 時(shí)間: 2025-4-1 19:38 作者: Collar 時(shí)間: 2025-4-2 01:53
Haemopoietic Cells as Targets for Gene Transfer, for the study of normal and abnormal haemopoiesis (Spooncer et al., 1988). Despite these advances, however, much remains to be learned about the structure and function of the haemopoietic system. This paper reviews current understanding of haemopoietic regulation as it pertains to gene transfer strategies.作者: 比喻好 時(shí)間: 2025-4-2 05:04 作者: aesthetic 時(shí)間: 2025-4-2 09:54
Book 2007niques - and yet remain a challenge for theoretical analysis. The present volume, based on a May 2005 workshop, examines and reviews the state-of-the-art in the development of new theoretical and computational methods to interpret the observed phenomena. Emphasis is on complex molecular processes in
