標(biāo)題: Titlebook: Vaccine Protocols; Andrew Robinson,Graham H. Farrar,Christopher N. Wi Book 19961st edition Humana Press 1996 [打印本頁(yè)] 作者: notable 時(shí)間: 2025-3-21 17:23
書(shū)目名稱Vaccine Protocols影響因子(影響力)
作者: Valves 時(shí)間: 2025-3-21 22:14
Temperature-Sensitive Mutant Vaccines,ly successful in controlling poliomyelitis are the prime example of this phenomenon. The three live attenuated strains developed by Sabin were derived from wild-type isolates by rapid sequential passage at high multiplicity of infection in monkey tissue in vitro and in vivo, a regimen that yielded v作者: 職業(yè)拳擊手 時(shí)間: 2025-3-22 03:48 作者: 容易懂得 時(shí)間: 2025-3-22 06:38
Development of Attenuated , Strains that Express Heterologous Antigens,s a system for delivering foreign antigens to the mammalian immune system. DNA capable of driving the expression of heterologous antigens can be introduced into . vaccine strains using a variety of approaches. In general, there are two common methods of expressing a foreign antigen in salmonellae: f作者: 補(bǔ)角 時(shí)間: 2025-3-22 11:49
Chimeric Proteins, several limitations. Large-scale growth of pathogens may be difficult to achieve and is not completely free of risk. Furthermore, purification of relevant antigenic components from such pathogens may be expensive and time-consuming. Another approach is the use of synthetic peptides corresponding to作者: 誘使 時(shí)間: 2025-3-22 13:04 作者: Badger 時(shí)間: 2025-3-22 20:56 作者: Nostalgia 時(shí)間: 2025-3-22 22:57 作者: Cardiac 時(shí)間: 2025-3-23 04:11
The Use of Adjuvants in Experimental Vaccines,preparation because of its extensive use in experimental vaccines in animals, its strong adjuvant effect, and the considerable literature describing its activity. The combination of mineral oil (Bayol 55) and dead mycobacterial organisms produces a specific cellular reaction in experimental animals.作者: FRAUD 時(shí)間: 2025-3-23 06:30
The Use of Adjuvants in Experimental Vaccines,iety of natural phospholipids or other polar amphiphiles can be used in an aqueous solution of an antigen to form either unilamellar or multilamellar spherules. The antigen(s) may either be lipid-soluble and insert into the artificial lipid bilayer, bmd to the bilayer, or become entrapped inside the作者: 責(zé)任 時(shí)間: 2025-3-23 09:41 作者: 外面 時(shí)間: 2025-3-23 16:35 作者: outer-ear 時(shí)間: 2025-3-23 20:37 作者: Ambulatory 時(shí)間: 2025-3-24 01:31 作者: Oversee 時(shí)間: 2025-3-24 04:09 作者: 消毒 時(shí)間: 2025-3-24 10:02
Immunological Characterization,igens, but also that they are in the correct immunological form (..). In general, this immunological characterization of a vaccine is interpreted as the ability of the preparation to invoke an appropriate immune response to its major constitutent antigens. The immune response in question may be in t作者: 侵蝕 時(shí)間: 2025-3-24 13:14
Severe Combined lmmunodeficient (SCID) Mice in Vaccine Assessment, be obtained from phase 1 human trials, in the vast majority of cases, it is not possible to challenge vaccine recipients with the specific infectious agent in order to assess protection. Therefore, prior to large-scale production of vaccines and their assessment in phase 2 and 3 clinical trials, th作者: NUL 時(shí)間: 2025-3-24 17:08 作者: Overthrow 時(shí)間: 2025-3-24 22:45 作者: 絕種 時(shí)間: 2025-3-25 02:16 作者: 翅膀拍動(dòng) 時(shí)間: 2025-3-25 05:19 作者: atopic-rhinitis 時(shí)間: 2025-3-25 10:31
Microencapsulation of Vaccines,vaccines would help to reduce the cost of vaccination, To tackle such issues, researchers are borrowing ideas from other areas of the pharmaceutical industry to try to improve the performance of vaccines and reduce the cost of these important health-care interventions.作者: peptic-ulcer 時(shí)間: 2025-3-25 12:09 作者: 規(guī)范就好 時(shí)間: 2025-3-25 16:19 作者: sed-rate 時(shí)間: 2025-3-25 23:32
Craig R. Pringleut. Historically, where optimal models have been applied to real cases (see Chapter 4), the fit between expected and observed behavior has been close enough to satisfy advocates and loose enough to encourage critics. Because alternative theories weigh facts differently, such empirical indeterminacie作者: 制度 時(shí)間: 2025-3-26 01:28
Alan Warnes,Anthony R. Fooksf archaeologists will wonder why we, their predecessors, viewed the Upper Paleolithic prehistory of Europe, a continent over 10,000,000 km. in area, primarily as an extension of the territory of the Périgord region of France, an area that measures under 10,000 km..” Since that time, a shift toward t作者: 講個(gè)故事逗他 時(shí)間: 2025-3-26 06:29 作者: NIP 時(shí)間: 2025-3-26 09:30
Michael J. Francisal models. For example, since the 1920s, the safe thermal processing of all high water activity, high pH food products has been derived from calculations based on models for the inactivation of microorganisms by heat. The best known example of this is the well-established model of the inactivation o作者: 相同 時(shí)間: 2025-3-26 15:02 作者: 幻影 時(shí)間: 2025-3-26 17:52
Duncan E. S. Stewart-Tull search for the foundations of rationality in the . structures of the experiencing subject. Although there has been considerable debate in the subsequent tradition about the status of subjectivity, transcendental philosophers agree that the principal source for an investigation into human rationalit作者: Sputum 時(shí)間: 2025-3-26 23:53
Duncan E. S. Stewart-Tullophers who would subsequently associate themselves with this movement, and eagerly reiterate Husserl’s maxim, was Martin Heidegger. The final story of the personal relationship of these two major figures of twentieth Century philosophy still remains to be told,1 but it is certain that it ended in pe作者: Somber 時(shí)間: 2025-3-27 01:20 作者: Morphine 時(shí)間: 2025-3-27 06:24 作者: 絕食 時(shí)間: 2025-3-27 09:58 作者: 徹底明白 時(shí)間: 2025-3-27 16:33 作者: LAVA 時(shí)間: 2025-3-27 18:25 作者: 左右連貫 時(shí)間: 2025-3-28 00:17 作者: Genome 時(shí)間: 2025-3-28 02:27 作者: pulmonary-edema 時(shí)間: 2025-3-28 07:26
Overview of Vaccines,tious agent, the extent of infection in the vaccinated individual is so low that disease does not occur. There is also increasing interest in designing vaccines that may be effective as a therapeutic measure. There are two contrasting types of infectious processes.作者: Forsake 時(shí)間: 2025-3-28 13:02 作者: Buttress 時(shí)間: 2025-3-28 14:36
Methods in Molecular Medicinehttp://image.papertrans.cn/v/image/980195.jpg作者: 泥瓦匠 時(shí)間: 2025-3-28 21:29 作者: 新義 時(shí)間: 2025-3-29 02:27
Development of Attenuated , Strains that Express Heterologous Antigens,ques that do not lead to the accumulation of undefined genetic lesions, which may compromise the immunogenicity of . growing in vivo. With this in mind, we will describe appropriate techniques for manipulating . with the aim of constructing effective oral vaccines.作者: 幻想 時(shí)間: 2025-3-29 06:43 作者: 驚呼 時(shí)間: 2025-3-29 10:12 作者: armistice 時(shí)間: 2025-3-29 13:23 作者: 周興旺 時(shí)間: 2025-3-29 17:00
The Use of Adjuvants in Experimental Vaccines,e humoral and cell-mediated immune responses but there may be concomitant adverse side-effects because of the reactogenicity of some types of mineral oil, particularly the formation of the epithelioid macrophage granuloma at the site of injection and local ulceration when the injection is given subc作者: 透明 時(shí)間: 2025-3-29 20:27 作者: 叢林 時(shí)間: 2025-3-30 02:58
Stimulation of Mucosal Immunity,uch as α4β7 integrin on lymphocytes and MAdCAM- on mucosal blood vessels (.), leads to dissemination of the mucosal immune response. One benefit of this, therefore, is that immunization of an accessible mucosal surface may induce an immune response at less accessible mucosal sites (such as the genit作者: CONE 時(shí)間: 2025-3-30 07:37 作者: Painstaking 時(shí)間: 2025-3-30 11:43 作者: Frequency 時(shí)間: 2025-3-30 16:01
Severe Combined lmmunodeficient (SCID) Mice in Vaccine Assessment,ecies that human pathogens will infect. This may be because of the lack of appropriate receptors, the presence of a functional immune system able to eliminate the pathogen, and the fact that models cannot always be relied on to re-create the normal pathophysiology.作者: Popcorn 時(shí)間: 2025-3-30 19:39
Clinical Trials,ning and conduct of clinical trials, this chapter will review the broad principles and stages involved in evaluating vaccines in humans, using examples from the literature. Details of methodological and other issues of particular relevance to vaccine evaluation are provided in Section 3.作者: 大看臺(tái) 時(shí)間: 2025-3-30 22:13
Book 19961st editionng genetic manipulation of viruses or bac- teria to produce live attenuated vaccines or inactivated toxins, and the production of synthetic peptides and conjugate vaccines. Second, a similar number of chapters describe more general techniques that can be used for the formulation, delivery, and asses作者: 細(xì)頸瓶 時(shí)間: 2025-3-31 04:52 作者: Phonophobia 時(shí)間: 2025-3-31 07:47
Mariagrazia Pizza,Maria Rita Fontana,Vincenzo Scarlato,Rino Rappuoli作者: 避開(kāi) 時(shí)間: 2025-3-31 12:35
Carla C. A. M. Peeters,Patrick R. Lagerman,Odo de Weers,Lukas A. Oomen,Peter Hoogerhout,Michel Beurr作者: 大門(mén)在匯總 時(shí)間: 2025-3-31 16:52
Andrew Robinson,Graham H. Farrar,Christopher N. Wi作者: FLACK 時(shí)間: 2025-3-31 19:21 作者: 使厭惡 時(shí)間: 2025-3-31 21:58
Alan Warnes,Anthony R. Fooksopean Paleolithic. This book centers on an interdisciplinary study of the Paleolithic of central Europe with a particular attention to Moravia, a region offering archaeological evidence from periods covering minimally the last half-million years, but particularly rich in evidence from the last 40,00作者: 大暴雨 時(shí)間: 2025-4-1 03:11
