標(biāo)題: Titlebook: Vaccine Adjuvants; Methods and Protocol Christopher B. Fox Book 2017 Springer Science+Business Media New York 2017 Human vaccines.In silico [打印本頁] 作者: DUBIT 時間: 2025-3-21 19:49
書目名稱Vaccine Adjuvants影響因子(影響力)
書目名稱Vaccine Adjuvants影響因子(影響力)學(xué)科排名
書目名稱Vaccine Adjuvants網(wǎng)絡(luò)公開度
書目名稱Vaccine Adjuvants網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Vaccine Adjuvants被引頻次
書目名稱Vaccine Adjuvants被引頻次學(xué)科排名
書目名稱Vaccine Adjuvants年度引用
書目名稱Vaccine Adjuvants年度引用學(xué)科排名
書目名稱Vaccine Adjuvants讀者反饋
書目名稱Vaccine Adjuvants讀者反饋學(xué)科排名
作者: Interdict 時間: 2025-3-21 22:10
Development of the CpG Adjuvant 1018: A Case Study,decades of use, it has become clear that there is a need for alternatives where alum-based adjuvants are suboptimal. Oligonucleotides containing unmethylated CpG sequences represent one alternative as they are potent stimulators of the vertebrate innate immune system through activation of Toll-like 作者: 祖先 時間: 2025-3-22 02:47
Syntheses of Human TLR8-Specific Small-Molecule Agonists,s evokes a distinct cytokine profile which favors the development of type 1 helper T cells. Focused exploration of structure-activity relationships in the imidazoquinolines has led to the identification of several novel human TLR8-specific agonists. The synthetic procedures for best-in-class analogu作者: 賞錢 時間: 2025-3-22 07:28 作者: Pcos971 時間: 2025-3-22 09:33
QS-21 Adjuvant: Laboratory-Scale Purification Method and Formulation Into Liposomes,nses in a variety of preclinical and clinical studies [1]. Its purification from the natural source is a lengthy and difficult process. The commercially available saponin mixture Quil-A. is a fraction of the bark extract containing a variety of saponins, including QS-21. In order to facilitate acces作者: scoliosis 時間: 2025-3-22 13:41
Purification of an Immunoadjuvant Saponin Fraction from , Leaves by Reversed-Phase Silica Gel Chromines is of interest due to their capacity to stimulate both humoral and cellular responses. The congener species . has saponins with chemical similarities and adjuvant activity comparable to that of . fraction Quil-A., with additional advantages of showing lower toxicity and reduced hemolytic activi作者: 和平主義者 時間: 2025-3-22 18:22
Biosynthetic Approaches to Squalene Production: The Case of Yeast,ditional natural resources of squalene are limited, alternatives for the production of squalene on industrial scale have been intensively explored during past years. The yeast . represents an attractive option due to elaborated techniques of genetic and metabolic engineering that can be applied to i作者: Muscularis 時間: 2025-3-22 22:15 作者: ATRIA 時間: 2025-3-23 05:21 作者: Irrigate 時間: 2025-3-23 06:11 作者: CYN 時間: 2025-3-23 13:34 作者: finale 時間: 2025-3-23 16:43
Manufacture of Oil-in-Water Emulsion Adjuvants,omposition and manufacturing, as well as optimization for safety and efficacy. Squalene has emerged as being particularly suitable for the manufacturing of safe oil-in-water (O/W) adjuvants for parenteral applications due to its biocompatibility and ability to be metabolized. Emulsion particle size 作者: insincerity 時間: 2025-3-23 20:36 作者: progestogen 時間: 2025-3-23 23:32
Production of Adjuvant-Loaded Biodegradable Particles for Use in Cancer Vaccines,associated antigens, and delivering these adjuvants as discrete packages is considered advantageous over delivery in soluble form. Here we describe in detail, methods for independently loading a range of adjuvants into polymer-based biodegradable particles. We also describe the means by which to cha作者: 纖細(xì) 時間: 2025-3-24 03:08 作者: 拱形面包 時間: 2025-3-24 08:25
Stressed Stability Techniques for Adjuvant Formulations,ty. These studies vastly help the development of stability indicating tests and the selection of stabilizing conditions for long term storage. In this chapter, we provide detailed protocols for the execution of forced degradation experiments that evaluate the robustness of adjuvant formulations agai作者: 為現(xiàn)場 時間: 2025-3-24 11:43
Particle Sizing of Nanoparticle Adjuvant Formulations by Dynamic Light Scattering (DLS) and Nanopar a sample. These technologies use the theory of Brownian motion by analyzing the random changes of light intensity scattered by particles in solution. Both techniques can be used to characterize particle size distribution of proteins and formulations in the nanometer to low micron range..Each method作者: 刪減 時間: 2025-3-24 18:25 作者: Mortar 時間: 2025-3-24 22:48
Determination of Protein Content in Alhydrogel,-Based Vaccines by ,-Phthalaldehyde Assay,wed by the quantification of the antigen available in the extract. Extraction procedures often result in less than 100 % desorption of the antigen from the alum adjuvant and may alter the conformation of the antigen, reducing the accuracy of the subsequent method used for quantification. There is no作者: PATHY 時間: 2025-3-24 23:44
Book 2017ulation, manufacturing, and characterization aspects involved. Beginning with an overview and a case study, the book then delves into .in silico. design, chemical synthesis, biosynthesis, and/or purification from natural raw materials of specific adjuvant molecules, adjuvant formulation approaches, 作者: follicle 時間: 2025-3-25 07:16 作者: corporate 時間: 2025-3-25 07:48
QS-21 Adjuvant: Laboratory-Scale Purification Method and Formulation Into Liposomes,o appropriately formulate QS-21 into cholesterol-containing, neutral liposomes which are known to decrease QS-21’s hemolytic activity while retaining the adjuvant effect. Methods for the physicochemical characterization of purified QS-21 and of the QS-21/liposome formulations are also described.作者: LAVA 時間: 2025-3-25 11:51 作者: Juvenile 時間: 2025-3-25 19:51 作者: 克制 時間: 2025-3-25 20:39
Production of Adjuvant-Loaded Biodegradable Particles for Use in Cancer Vaccines, adjuvant-loaded particles have the potential to be used in dendritic cell-based uptake experiments performed in vitro or to be used in preclinical cancer vaccine research applications where they can be co-delivered with antigen-loaded particles or some other vaccine component comprising antigenic material.作者: 百靈鳥 時間: 2025-3-26 03:37 作者: Lipoma 時間: 2025-3-26 06:03
1064-3745 e results.Contains key notes and implementation advice from This collection seeks to elucidate the practical methods necessary for successful adjuvant development, with a particular focus on the synthesis, formulation, manufacturing, and characterization aspects involved. Beginning with an overview 作者: 注意力集中 時間: 2025-3-26 11:06
Methods to Prepare Aluminum Salt-Adjuvanted Vaccines, However, preparing aluminum salts and aluminum salt-adjuvanted vaccines in a consistent manner remains challenging. This chapter discusses methods to prepare aluminum salts and aluminum salt-adjuvanted vaccines, factors to consider during preparation, and methods to characterize the vaccines after preparation.作者: metropolitan 時間: 2025-3-26 15:10
Lyophilization of Adjuvanted Vaccines: Methods for Formulation of a Thermostable Freeze-Dried Produstem, that require bedside-mixing prior to immunization. Here we present an example of a lyophilization cycle that we have used to successfully freeze-dry an adjuvanted protein formulation in a single vial.作者: 爭吵加 時間: 2025-3-26 18:26
Stressed Stability Techniques for Adjuvant Formulations, chapter, we provide detailed protocols for the execution of forced degradation experiments that evaluate the robustness of adjuvant formulations against thermal, mechanical, freeze-thawing, and photo stresses.作者: 上下連貫 時間: 2025-3-27 00:23
Purification of an Immunoadjuvant Saponin Fraction from , Leaves by Reversed-Phase Silica Gel Chromty. Here we describe in detail the methods for preparing the aqueous extract from . leaves, as well as the purification of the bioactive saponin fraction QB-90 using silica reversed-phase chromatography.作者: abject 時間: 2025-3-27 03:20 作者: Acupressure 時間: 2025-3-27 07:58
Manufacturing Methods for Liposome Adjuvants,f these systems. Within this chapter we explore manufacturing processes that can be used for the production of liposomal adjuvants, and we outline new manufacturing methods can that offer fast, scalable, and cost-effective production of liposomal adjuvants.作者: 不如樂死去 時間: 2025-3-27 11:37
Preparing an Adjuvanted Thermoresponsive Gel Formulation for Sublingual Vaccination,tudies with various antigens suggest that the mucoadhesive, adjuvanted TRG formulation enabled increased contact of the vaccine antigen with the mucosa, resulting in increased mucosal response(s) with a potential for antigen dose reduction.作者: 出生 時間: 2025-3-27 15:41 作者: engender 時間: 2025-3-27 19:31 作者: Coronary-Spasm 時間: 2025-3-27 21:56
Overview of Vaccine Adjuvants: Introduction, History, and Current Status,apter is to define the concept, need, and mechanism of adjuvants in the vaccine field while describing its history, present use, and future prospects. More details on individual adjuvants and their formulation, development, mechanism, and use will be covered in depth in the next chapters.作者: 禁止 時間: 2025-3-28 04:55
In Silico Adjuvant Design and Validation, produced in large amounts by activated innate cells including DCs. In silico identified small molecule CCR4 antagonists inhibited the migration of Tregs both in vitro and in vivo and when combined with vaccine antigens, significantly enhanced protective immune responses in experimental models.作者: follicular-unit 時間: 2025-3-28 08:04 作者: Intellectual 時間: 2025-3-28 13:54 作者: chandel 時間: 2025-3-28 18:17 作者: 脆弱么 時間: 2025-3-28 19:08 作者: Armory 時間: 2025-3-29 01:48
Alberto Fernández-Tejada,William E. Walkowicz,Derek S. Tan,David Y. Ginat presbyopia is a lens based phenomenon and that there may be a lens mediated drift towards a more hyperopic refractive state with ageing. The blur of the image formed by the lens changes as a function of age and accommodative state. Ocular image quality varies with accommodative state and pupil si作者: 慢慢啃 時間: 2025-3-29 06:17 作者: 百科全書 時間: 2025-3-29 10:42
Anna C. A. Yendo,Fernanda de Costa,Carla Kauffmann,Juliane D. Fleck,Grace Gosmann,Arthur G. Fett-Nets relatively fluid and membrane-like judged by its electron microscopic appearance in negatively stained preparations of the organism [2]. Such flagellar sheaths are not common among bacteria; a well-known parallel is the sheathed flagellum of ., and sheathed flagella are sometimes present, although作者: dithiolethione 時間: 2025-3-29 13:49 作者: 震驚 時間: 2025-3-29 15:51 作者: 里程碑 時間: 2025-3-29 23:24
Yvonne Perrie,Elisabeth Kastner,Swapnil Khadke,Carla B. Roces,Peter Stone investigators whose current concepts have been brought together in this book by authors from five different countries. Three major groups with many subgroups have made inroads into our better understanding of the liver. The first of these comprises the basic scientists whose study of single hepatoc作者: aesthetician 時間: 2025-3-30 01:08 作者: heckle 時間: 2025-3-30 06:39 作者: 一加就噴出 時間: 2025-3-30 12:05
Jean Haenslerco- logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often prelimi- nary reports on a very limited number of patients. Certain general journals frequently publish good indepth reviews of cancer topics, and publis作者: Infuriate 時間: 2025-3-30 13:54 作者: Engaged 時間: 2025-3-30 20:02
Michelle Y. Chan,Timothy S. Dutill,Ryan M. Kramerd International Conference on Alzheimer‘s and Parkinson‘s Diseases: Basic and Therapeutic Strategies, held at the Kyoto Park Hotel in Kyoto, Japan, on November 6-10, 1989. The First Conference was held at the Aviya Sonesta Hotel in Eilat, Israel, on March 24-27, 1985. The record of this First Confer作者: 黃油沒有 時間: 2025-3-31 00:42 作者: BUCK 時間: 2025-3-31 01:34 作者: Synchronism 時間: 2025-3-31 07:11 作者: 方便 時間: 2025-3-31 09:11 作者: 感染 時間: 2025-3-31 14:27
Christopher B. FoxIncludes cutting-edge methods and protocols in the field of vaccine adjuvant research.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from 作者: Protein 時間: 2025-3-31 19:19
978-1-4939-8202-8Springer Science+Business Media New York 2017作者: 錢財 時間: 2025-4-1 01:37
Vaccine Adjuvants978-1-4939-6445-1Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: Tincture 時間: 2025-4-1 04:36
Development of the CpG Adjuvant 1018: A Case Study,m demonstrated induction of substantially higher antibody titers and a favorable safety profile for 1018. Most importantly, clinical studies with HBsAg vaccination consistently demonstrate more rapid induction of protective antibody titers with 1018 compared to alum in all populations studied, inclu作者: 管理員 時間: 2025-4-1 09:59
Book 2017adily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Practical and authoritative, .Vaccine Adjuvants: Methods and Protocols. aims to facilitate vaccine adjuvant product development efforts, making them more accessible, manufacturable, and better character作者: 王得到 時間: 2025-4-1 12:56 作者: Adj異類的 時間: 2025-4-1 14:54 作者: 嚴(yán)厲譴責(zé) 時間: 2025-4-1 22:24
