標(biāo)題: Titlebook: Unraveling the Exposome; A Practical View Sonia Dagnino,Anthony Macherone Book 2019 Springer International Publishing AG, part of Springer [打印本頁(yè)] 作者: hedonist 時(shí)間: 2025-3-21 16:48
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書目名稱Unraveling the Exposome讀者反饋學(xué)科排名
作者: MARS 時(shí)間: 2025-3-21 23:44
The Public Health Exposomeh. The exposome represents the totality of exogenous (external) and endogenous (internal) exposures from conception onwards, simultaneously distinguishing, characterizing, and quantifying etiologic, mediating, moderating, and co-occurring risk and protective factors and their relationship to disease作者: paragon 時(shí)間: 2025-3-22 04:21
The U.S. Military and the Exposomediverse environments, under a variety of stressors, with pressure to perform and execute tasks under any conditions. The US military is unique in the range of environments they deploy to, as well as the kinds of industrial chemicals and materials they are exposed to, making them one of the most dyna作者: 教育學(xué) 時(shí)間: 2025-3-22 07:18 作者: Harness 時(shí)間: 2025-3-22 09:48 作者: 流出 時(shí)間: 2025-3-22 13:54 作者: 肥料 時(shí)間: 2025-3-22 20:18 作者: 包庇 時(shí)間: 2025-3-23 01:10
The Food Exposomemed and the variability of the amount and frequency of intake according to food preference, season, and other individual characteristics. Classical approaches to estimating dietary intake have used dietary assessment instruments such as questionnaires and food composition tables. However, these are 作者: hieroglyphic 時(shí)間: 2025-3-23 03:30
The Dust Exposomeinants varies by a number of factors including location, nearby objects, and activities. Indoor locations that contain furniture, appliances, and other electronic goods produce dust enriched with chemical additives used in the manufacturing process. Classes of chemicals commonly found in dust includ作者: sterilization 時(shí)間: 2025-3-23 07:46
From the Outside In: Integrating External Exposures into the Exposome Conceptso nutrients, drugs, infectious agents, the microbiome, physical stress, and psychosocial stress. But where do those exposures come from, and what can we do about them? This chapter will focus on two distinct but interrelated questions: (1) Why understanding the environment outside of the body is cr作者: 蒸發(fā) 時(shí)間: 2025-3-23 10:30 作者: Antarctic 時(shí)間: 2025-3-23 17:45
Exposome-Wide Association Studies: A Data-Driven Approach for Searching for Exposures Associated witf disease. The human exposome has been tentatively defined as the totality of environmental exposures such as dietary nutrients, pharmaceutical drugs, infectious agents, and pollutants encountered from birth to death. Much as human genetics has benefited from high-throughput profiling in the form of作者: 出處 時(shí)間: 2025-3-23 19:48 作者: noxious 時(shí)間: 2025-3-23 22:43 作者: 階層 時(shí)間: 2025-3-24 06:15 作者: 兵團(tuán) 時(shí)間: 2025-3-24 09:34 作者: fender 時(shí)間: 2025-3-24 11:16 作者: 冷淡周邊 時(shí)間: 2025-3-24 17:41 作者: A簡(jiǎn)潔的 時(shí)間: 2025-3-24 19:47
The Public Health Exposomeers of exposure, biomarkers of disease, disease phenotype, clinical outcomes, and population level disparities, across the lifespan, and between generations. This chapter proposes a new taxonomy for sequencing the public health exposome first described by Wild as the eco-exposome. The aim of this ch作者: aneurysm 時(shí)間: 2025-3-25 01:59
The U.S. Military and the Exposome has led the military to prioritize efforts for exposure surveillance, mitigation strategies, and leading-edge research initiatives. In this chapter, we will discuss the unique operational environments and exposures warfighters encounter, as well as the biomonitoring, military records for exposures,作者: 眨眼 時(shí)間: 2025-3-25 03:58 作者: 不愿 時(shí)間: 2025-3-25 11:33
Epigenetics and the Exposomeosures such as tobacco smoke, air pollution, and metal exposures in population-based studies. On the other hand, deviant DNA methylation is a major epigenetic mechanism of epigenetic silencing in a wide range of human diseases including cancers. Epigenetic modifications might play a prominent role i作者: 手銬 時(shí)間: 2025-3-25 15:37
Metabonomicshe size and diversity of the chemical space that metabolites occupy means that measuring the human metabolome via serum, urine, or other biofluids or tissues represents a huge analytical challenge, addressed by the application of high-resolution platforms, typically incorporating liquid- and/or gas-作者: neutrophils 時(shí)間: 2025-3-25 19:32
Transcriptomics within the Exposome Paradigme ubiquitous mixtures. Although environmental exposures occur to mixtures of chemicals rather than to individual agents, most of the toxic effects of air pollutants are ascribed to single chemicals. There is a growing feeling in both the scientific and regulatory communities, however, that there is 作者: FLIP 時(shí)間: 2025-3-25 20:45
The Food Exposomes. Several 100 food-derived compounds can be simultaneously measured as part of the human exposome in very small human biospecimens collected in large populations. These approaches and their implementation in dietary-wide association studies are reviewed. This could significantly advance nutritional作者: 占線 時(shí)間: 2025-3-26 03:14 作者: Ingenuity 時(shí)間: 2025-3-26 05:39
From the Outside In: Integrating External Exposures into the Exposome Conceptsuch as social and built environment as well as behavioral factors. The grand challenge lies in how to provide a comprehensive and rigorous characterization of the external environment on the exposome scale. This chapter will discuss作者: 推遲 時(shí)間: 2025-3-26 10:06 作者: 公社 時(shí)間: 2025-3-26 15:22
Exposome-Wide Association Studies: A Data-Driven Approach for Searching for Exposures Associated wite association study” (EWAS). First, we will describe the philosophy behind such a study, including transparency and mitigation of the chances for selection biases. Second, we will describe how to mitigate chances of type 1 error and investigate the possibility of true signals in a sea of possible fa作者: 沉著 時(shí)間: 2025-3-26 17:46
EXPOsOMICs: Meet-in-the-Middle and Network Perturbations of cancer as intermediate steps between exposure to carcinogens and the cancer phenotype, according to the “meet-in-the-middle” concept. We use examples derived from the study of mutational spectra in tumours and benzo(a)pyrene and bisphenol A as model carcinogens. We suggest conceptualising the d作者: 無(wú)聊的人 時(shí)間: 2025-3-26 21:01 作者: 百靈鳥 時(shí)間: 2025-3-27 03:49
them contain explicit or implicit references to sex. Out of these jokes, (39) and (148) will strike most people as the most explicitly sexual and, therefore, “dirtiest,” while (4) is perhaps the least explicit of them and, therefore, the most socially acceptable. These two extremes determine the ra作者: 一回合 時(shí)間: 2025-3-27 06:15
niques for semantic methods, which are currently studied and developed in many academic and industry centers over the world. The editors hope that the book can be useful for graduate and PhD students of computer science, as well as for mature academics, researchers and practitioners interested in de作者: 滔滔不絕的人 時(shí)間: 2025-3-27 10:30 作者: 作繭自縛 時(shí)間: 2025-3-27 14:48 作者: Anticonvulsants 時(shí)間: 2025-3-27 18:33 作者: Dappled 時(shí)間: 2025-3-27 21:57
D. A. Sarigiannism a cross-linguistic perspective. Our discussion is focused on Chinese, where there exist multiple fully developed systems. We show that while the general formulation of semantic role labeling as a machine learning problem works well in Chinese, as in English, a semantic role labeling system must in作者: 運(yùn)氣 時(shí)間: 2025-3-28 03:41
ng w.r.t. the instance size is crucial. A key notion that ensures tractability in ..schemata is ., i.e., the absence of interaction between the functional participation constraints and the other constructs. We provide a precise syntactic characterization of separable ..schemata by means of a necessa作者: 噴油井 時(shí)間: 2025-3-28 08:09
Yuxia Cui,David Balshawer interactions. They give a broad overview of how semantic technologies have been applied in different e-government projects funded from the European program for ICT Research and Development, and they cover a wide spectrum of semantic technologies such as development of domain and service ontologie作者: 放肆的你 時(shí)間: 2025-3-28 13:47
positions can be expressed through further articulation (Effability), when evidence suggests that the opposite is true: propositions are in general ineffable (Ineffability). I will close the chapter by trying to resist the idea, propounded by some ineffabilist theorists, to the effect that our thoug作者: accrete 時(shí)間: 2025-3-28 16:24 作者: Small-Intestine 時(shí)間: 2025-3-28 22:49 作者: regale 時(shí)間: 2025-3-28 23:59 作者: Dna262 時(shí)間: 2025-3-29 07:01 作者: 捐助 時(shí)間: 2025-3-29 11:15 作者: opinionated 時(shí)間: 2025-3-29 12:41 作者: Nebulous 時(shí)間: 2025-3-29 19:33 作者: 矛盾 時(shí)間: 2025-3-29 22:27 作者: 美麗的寫 時(shí)間: 2025-3-30 01:12
Augustin Scalbert,Inge Huybrechts,Marc J. Gunterlementation of its subsystems and a prototypical realization of a proper business scenario are presented. Thus the book goes way beyond current service-based software technologies by providing a coherent and co978-3-642-09735-5978-3-540-78617-7作者: 可互換 時(shí)間: 2025-3-30 05:57
tions for measuring the Exposome through external exposures. Section four provides an overview on statistical and computational techniques- including big data analysis - for characterizing the Exposome. Section978-3-030-07739-6978-3-319-89321-1作者: 外表讀作 時(shí)間: 2025-3-30 10:14 作者: 嗎啡 時(shí)間: 2025-3-30 14:15
