標(biāo)題: Titlebook: Uncertainty in Pharmacology; Epistemology, Method Adam LaCaze,Barbara Osimani Book 2020 Springer Nature Switzerland AG 2020 Drug Developmen [打印本頁] 作者: 贊美 時(shí)間: 2025-3-21 18:02
書目名稱Uncertainty in Pharmacology影響因子(影響力)
書目名稱Uncertainty in Pharmacology影響因子(影響力)學(xué)科排名
書目名稱Uncertainty in Pharmacology網(wǎng)絡(luò)公開度
書目名稱Uncertainty in Pharmacology網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Uncertainty in Pharmacology被引頻次
書目名稱Uncertainty in Pharmacology被引頻次學(xué)科排名
書目名稱Uncertainty in Pharmacology年度引用
書目名稱Uncertainty in Pharmacology年度引用學(xué)科排名
書目名稱Uncertainty in Pharmacology讀者反饋
書目名稱Uncertainty in Pharmacology讀者反饋學(xué)科排名
作者: Tracheotomy 時(shí)間: 2025-3-21 20:14
Causal Insights from Failure: Post-marketing Risk Assessment of Drugs as a Way to Uncover Causal Mec to understand the causal mechanism underlying a certain outcome. Here, we base our argument on a particular philosophical framework, causal dispositionalism, which urges that causes should be understood as complex, intrinsic, tendential and context-sensitive. Applied to pharmacology, dispositionali作者: 喊叫 時(shí)間: 2025-3-22 02:27
Extrapolating from Model Organisms in Pharmacologyategies of extrapolation: enumerative induction, comparative process tracing, phylogenetic reasoning, and robustness reasoning. We argue that evidence of mechanisms plays a crucial role in several strategies for extrapolation and in the underlying logic of extrapolation: the more directly a strategy作者: 玷污 時(shí)間: 2025-3-22 06:02
Mechanistic vs Statistical Extrapolation in Preclinical Research in Psychiatry: Challenging the Rece pathological states in organisms, thanks to a step by step comparison of causal pathways. . takes the form: . cause C brings out effect E in animal through causal pathway M, . M is similar in animals and humans, . therefore C will likely bring out E in humans. As the example of psychiatric research作者: Glucose 時(shí)間: 2025-3-22 12:03
Analogy-Based Inference Patterns in Pharmacological Researchwork for the purpose of formally exploring different analogy-based inference patterns with respect to their justification in pharmacological risk assessment. By relating formal explications of similarity, analogy, and analog simulation, three sources of confirmatory support for a causal hypothesis a作者: 陰郁 時(shí)間: 2025-3-22 13:19
In Silico Clinical Trials: A Possible Response to Complexity in Pharmacologyreatment is administered make pharmacological research extremely difficult. Due to the inability to completely predict how a product will affect individual patients, it’s not unusual for a drug to show serious problems during clinical tests after having performed well in pre-clinical and laboratory 作者: Nausea 時(shí)間: 2025-3-22 19:06 作者: Inscrutable 時(shí)間: 2025-3-22 22:20
“Caught in the Amber”: A Sketch of Chemical Underdeterminationmature, on the other, the shift of the object range by introducing new substances can change the dispositional description of the phenomena one is aiming at. Mainstream philosophers of science sometimes discuss the former as what could be called “epistemological” underdetermination, whereas the latt作者: Paraplegia 時(shí)間: 2025-3-23 01:28 作者: Immunization 時(shí)間: 2025-3-23 08:35
Learning by Difference: Placebo Effects and Specific Efficacy in Pharmacological RCTs trial arms. We label this the “assumption of specific efficacy”. There are a number of situations in which the assumption of specific efficacy does not hold. We describe the epistemic consequences that arise in these situations and discuss strategies for preserving the internal validity of randomiz作者: Atrium 時(shí)間: 2025-3-23 12:03 作者: 圓柱 時(shí)間: 2025-3-23 17:45 作者: Deject 時(shí)間: 2025-3-23 21:45 作者: Shuttle 時(shí)間: 2025-3-24 01:54
Modelling Individual Response to Treatment and Its Uncertainty:A Review of Statistical Methods and Crived from appropriate studies and provided in a way that easily transforms from the statistical model into clinical practice. This chapter discusses four methodological strategies to provide information for treatment decisions: subgroup analysis, regression models, models for ., and prediction mode作者: 合乎習(xí)俗 時(shí)間: 2025-3-24 06:16
Epistemic Gains and Epistemic Games: Reliability and Higher Order Evidence in Medicine and Pharmacol our game with nature and the scientific ecosystem: an “elitist” and a “pluralist” approach. The former is focused on reliability as minimisation of random and systematic error, and is grounded on a categorical approach to causal assessment, whereas the latter is more focused on the high context-sen作者: preservative 時(shí)間: 2025-3-24 07:19
Values in Pharmacologyof values that have an influence in pharmacology. Furthermore, a criterion is proposed to distinguish between legitimate and illegitimate influence of non-epistemic values in pharmacological science. According to this proposal, practical considerations may not legitimately lower the demands of evide作者: 媒介 時(shí)間: 2025-3-24 13:49
Book 2020uses in particular on the diverse sources of uncertainty, the different kinds of uncertainty that there are, and the diverse ways in which these uncertainties are (or could be) addressed. Compared with the more basic sciences, such as chemistry or biology, pharmacology works across diverse observabl作者: jaunty 時(shí)間: 2025-3-24 18:43
Defining Aspects of Mechanisms: Evidence-Based Mechanism (Evidence , a Mechanism), Mechanism-Based Elies two separate concepts:.These two terms are more specific than the ambiguous terms “evidence of mechanism” and “mechanistic evidence”..Mechanistic reasoning combines these two approaches with the results of probabilistic clinical observations.作者: 后來 時(shí)間: 2025-3-24 20:41
Extrapolating from Model Organisms in Pharmacology establishes mechanistic similarities between a model and humans, the more reliable the extrapolation. We present case studies from the research on atherosclerosis and the development of statins, that illustrate these strategies and the role of mechanistic evidence in extrapolation.作者: 工作 時(shí)間: 2025-3-24 23:27 作者: Range-Of-Motion 時(shí)間: 2025-3-25 06:34
A Millian Look at the Logic of Clinical Trials and, more generally, hypotheses of statistical causality, are provided by an appropriate statistical version of such a venerable procedure as the method of difference put forward by John Stuart Mill.作者: 弓箭 時(shí)間: 2025-3-25 10:47 作者: 殺死 時(shí)間: 2025-3-25 13:38 作者: 性滿足 時(shí)間: 2025-3-25 18:54 作者: 不溶解 時(shí)間: 2025-3-25 23:09
Epistemic Gains and Epistemic Games: Reliability and Higher Order Evidence in Medicine and Pharmacold for defeasibility of causal inference in such domains. I then present a system for probabilistic causal assessment from heterogenous evidence that makes justice of concerns from both positions, while also incorporating “higher order evidence” (evidence/information about the evidence itself) in hypothesis confirmation.作者: Externalize 時(shí)間: 2025-3-26 03:53 作者: 孤獨(dú)無助 時(shí)間: 2025-3-26 08:22 作者: jocular 時(shí)間: 2025-3-26 10:27 作者: 半導(dǎo)體 時(shí)間: 2025-3-26 14:45 作者: 織布機(jī) 時(shí)間: 2025-3-26 17:05
In Silico Clinical Trials: A Possible Response to Complexity in Pharmacology doing research, thought to be more adequate to address biological complexity. In this chapter we analyze such a view by showing how these new computational strategies enhance and implement traditional approaches rather than changing the nature of clinical investigation. An epistemic look at ISCTs s作者: Projection 時(shí)間: 2025-3-26 23:38 作者: 清洗 時(shí)間: 2025-3-27 04:27 作者: intellect 時(shí)間: 2025-3-27 07:01
Modelling Individual Response to Treatment and Its Uncertainty:A Review of Statistical Methods and Con-making. At the moment, most energy is spent in the discovery of biomarkers which help to grasp patient treatment interaction. Less energy is spent in corresponding validation studies and the process of translating statistical results into clinical practice. Furthermore, clinical studies that prov作者: judiciousness 時(shí)間: 2025-3-27 10:35
Book 2020ch intersects the deeply intertwined dimensions of pharmacological research, pharmaceutical regulation and the related economic environment. The book is a collective endeavour with in-depth contributions from experts in pharmacology, philosophy of medicine, statistics, scientific methodology, formal作者: FACT 時(shí)間: 2025-3-27 14:53 作者: 線 時(shí)間: 2025-3-27 21:31 作者: 心胸開闊 時(shí)間: 2025-3-28 00:28
Catherine Belzung,Etienne Billette de Villemeur,Ma?l Lemoineend delay (EED), and peak signal noise ratio (PSNR). The existing researches HRDSS and HSSFF are used to analyze the CATSA-PABE-HCA. The PSNR of the CATSA-PABE-HCA for 150 Kbps of bit rate is 2400 which is high than the HRDSS and HSSFF.作者: 馬具 時(shí)間: 2025-3-28 04:48 作者: 廣大 時(shí)間: 2025-3-28 07:10
Jürgen Landes1st century, Muslims became an integrated part of Brazilian, Argentine, Colombian and other Latin American societies. At the same time, there is a global connection between Arab migrant communities, which makes the study of the diffusion of Muslim communities in Ibero-America relevant.作者: contradict 時(shí)間: 2025-3-28 13:55
Adam LaCaze,Karl Winckelle development” and “green economy,” as well as the strengthening of alarmist greening of mass public consciousness. Comparative analysis of both “versions” of geographical determinism demonstrates not congruent but their close coincidence with the paradigmatic foundations of the synergetic research matrix.作者: 游行 時(shí)間: 2025-3-28 17:44 作者: 黃瓜 時(shí)間: 2025-3-28 20:31 作者: DOTE 時(shí)間: 2025-3-29 01:45
d for researchers in the fields of Membrane Computing, Evolutionary Computing and Genetic Algorithms, DNA and Molecular Computing, Biological Computing, Swarm Intelligence, Autonomy-Oriented Computing, Cellular978-3-642-37501-9978-3-642-37502-6Series ISSN 2194-5357 Series E-ISSN 2194-5365 作者: 充滿人 時(shí)間: 2025-3-29 05:29
Barbara Osimanist functional for each different vehicle over varying road terrain. This results in performance not possible with a fixed gain controller. The adaptive controller has been tested on a number of vehicles with excellent results, some of which are presented here.作者: Brocas-Area 時(shí)間: 2025-3-29 08:39 作者: 名字 時(shí)間: 2025-3-29 11:29 作者: CRAFT 時(shí)間: 2025-3-29 16:13
Jeffrey K. Aronson2% precision, 88% recall, and 90% .1 score. Thus, the performance of the model proposed using Na?ve Bayes classifier is very useful for predicting the outcomes of the petitions related to the employment matters of government servants and also of the employees of local authorities and government corporations and companies.作者: Emasculate 時(shí)間: 2025-3-29 22:27
Federico Boem,Ilaria Malagrinò,Marta Bertolasok. In this paper, a Hadamard transform-based compression technique is discussed for image compression with the consideration of different designing parameters of an image signal. In that manner, this work helps us to select the transform and source coding schemes for the compression of image data inside the wireless multimedia sensor network.作者: 陳腐的人 時(shí)間: 2025-3-30 00:30
Elena Rocca,Rani Lill Anjum,Stephen Mumfordbrain-mobile interface for omnipresent, prevalent computing. We eventually construct a sophisticated mobile-based EEG monitoring system by combining signal processing algorithm with an Android mobile application and we verify its effectiveness using real-time EEG data.作者: 圓柱 時(shí)間: 2025-3-30 07:15 作者: sphincter 時(shí)間: 2025-3-30 12:06
Klaus Ruthenbergloud show sample informative words from different stories. The proposed approach involves context while deriving the topics using synsets. Entropy value is 1.5 for varied datasets; entropy value ensures independence of topic and similarity between topics’ words.作者: GLUE 時(shí)間: 2025-3-30 14:18 作者: delusion 時(shí)間: 2025-3-30 19:05 作者: 打擊 時(shí)間: 2025-3-30 23:22
ization recovery is considered to be one of the most effective methods due to its economic benefits and feasibility. However, there are still many tasks to the realization of commercial hydrate recovery..In this study, we combined the continuity equation, the kinetic reaction equation and other auxi作者: 態(tài)學(xué) 時(shí)間: 2025-3-31 04:19 作者: Visual-Field 時(shí)間: 2025-3-31 08:37 作者: 聽寫 時(shí)間: 2025-3-31 11:01
