標(biāo)題: Titlebook: Sirtuins; Riekelt H. Houtkooper Book 2016 Springer Science+Business Media Dordrecht 2016 Sirtuin.Aging.Metabolic Disease.Nicotinamide Aden [打印本頁(yè)] 作者: 吸收 時(shí)間: 2025-3-21 19:13
書目名稱Sirtuins影響因子(影響力)
書目名稱Sirtuins影響因子(影響力)學(xué)科排名
書目名稱Sirtuins網(wǎng)絡(luò)公開度
書目名稱Sirtuins網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Sirtuins被引頻次
書目名稱Sirtuins被引頻次學(xué)科排名
書目名稱Sirtuins年度引用
書目名稱Sirtuins年度引用學(xué)科排名
書目名稱Sirtuins讀者反饋
書目名稱Sirtuins讀者反饋學(xué)科排名
作者: progestin 時(shí)間: 2025-3-21 23:06
https://doi.org/10.1007/978-94-024-0962-8Sirtuin; Aging; Metabolic Disease; Nicotinamide Adenine Dinucleotide; Physiology; diabetes作者: CLASP 時(shí)間: 2025-3-22 01:43 作者: Mumble 時(shí)間: 2025-3-22 08:18 作者: 微不足道 時(shí)間: 2025-3-22 09:46
Sirtuins978-94-024-0962-8Series ISSN 1567-2530 Series E-ISSN 2542-9973 作者: HAIL 時(shí)間: 2025-3-22 15:29
Peter Chhoy,Kristin A. Anderson,Kathleen A. Hershberger,Frank K. Huynh,Angelical S. Martin,Eoin McDo作者: TAG 時(shí)間: 2025-3-22 19:06 作者: Ingenuity 時(shí)間: 2025-3-22 23:42
Jaewon J. Lee,Karina N. Gonzalez Herrera,Marcia C. Haigis作者: altruism 時(shí)間: 2025-3-23 04:53 作者: 太空 時(shí)間: 2025-3-23 06:06
Selma Masri,Marina Maria Bellet,Paolo Sassone-Corsi作者: Phenothiazines 時(shí)間: 2025-3-23 13:26
Biochemistry and Enzymology of Sirtuins,ies of these enzymes and how they are regulated in cells. In particular, emphasis is given to mechanisms that alter sirtuin levels and activities in mammalian cells. Several sirtuin assays are also discussed. This chapter provides a broad overview of the enzymology and biological properties of this 作者: analogous 時(shí)間: 2025-3-23 14:27 作者: 幻想 時(shí)間: 2025-3-23 21:04
Sirtuins and the Circadian Clock: Epigenetic and Metabolic Crosstalk,abolism and epigenetics are closely linked opens new directions that need to be explored in terms of circadian metabolic regulation and how this modulates a host of epigenetic modifying enzymes and chromatin remodelers.作者: DAUNT 時(shí)間: 2025-3-24 01:15
Sirtuin Activation by Small Molecules,IRT1720 and SIRT2104, have now been reported to extend lifespan in mice fed a standard diet (Mercken et al, 2014; Mitchell et al, 2014) making SIRT1 an attractive target for therapeutic interventions for a variety of age related diseases. This review will address recent progress, controversies and c作者: 圖表證明 時(shí)間: 2025-3-24 03:58
NAD+ as a Pharmacological Tool to Boost Sirtuin Activity,bolic diseases. In this chapter, I will discuss the NAD. synthesis and breakdown pathways as their combined action determines NAD. levels. Furthermore, I will outline the pharmacological ways to boost NAD. levels and treat inherited and acquired metabolic diseases.作者: 露天歷史劇 時(shí)間: 2025-3-24 09:47
SIRT1 in Metabolic Health and Disease,le against neurodegenerative diseases and cancer, among others. Here, we aim to review our current knowledge on SIRT1 actions, with special emphasis on what mammalian animal models have taught us on the possibility of targeting complex diseases through SIRT1 activation.作者: GRACE 時(shí)間: 2025-3-24 11:59
Book 2016sm, but also aging and lifespan regulation. As such, sirtuins are strong targets for the treatment of age-related metabolic diseases, including obesity, diabetes, and cancer. Indeed, many research groups as well as pharmaceutical companies discovered food components and/or drugs that target the sirt作者: GOAT 時(shí)間: 2025-3-24 16:51
Biochemistry and Enzymology of Sirtuins,on characterized for these enzymes is protein lysine N-(epsilon)-deacetylation, which also produces nicotinamide and a novel compound called 2′-.-acetyl-ADPR as co-products. This reaction is catalyzed by an active site that is highly conserved across evolutionary time, and this reaction has been obs作者: 價(jià)值在貶值 時(shí)間: 2025-3-24 20:01 作者: fulcrum 時(shí)間: 2025-3-25 02:11 作者: 牢騷 時(shí)間: 2025-3-25 03:45
SIRT1 in Metabolic Health and Disease,s rapidly envisioned. More than a decade later, SIRT1 has been demonstrated to be at the pinnacle of metabolic control and metabolic adaptation in diverse organisms, including mammals. The activation of SIRT1 has been shown to be protective against metabolic damage and also holds promise in the batt作者: 尖叫 時(shí)間: 2025-3-25 09:08
Deacetylation by SIRT3 Relieves Inhibition of Mitochondrial Protein Function,n acetylation is regulated by the sirtuin SIRT3, which has been reported to control several metabolic pathways. While the functional relevance of protein acetylation is likely specific for proteins in different pathways, a picture is emerging for mitochondrial protein acetylation to be an important 作者: Organization 時(shí)間: 2025-3-25 14:28 作者: allergen 時(shí)間: 2025-3-25 17:51 作者: tendinitis 時(shí)間: 2025-3-25 22:11 作者: 噴出 時(shí)間: 2025-3-26 03:02 作者: conduct 時(shí)間: 2025-3-26 05:14
Sirtuins and Aging,a molecular level, these diseases are associated with a plethora of pathophysiological mechanisms, including deficiency in nutrient sensing, proteostasis, and mitochondrial function. Sirtuins have been implicated in the age-related malfunctioning of these pathways and are thought to be involved in t作者: 捕鯨魚叉 時(shí)間: 2025-3-26 08:58
Sirtuins and the Circadian Clock: Epigenetic and Metabolic Crosstalk,lso deacetylates specific elements of the clock machinery and modifies histones to regulate gene expression. In this chapter, we review the current understanding of the field on the interrelationship between SIRT1 and the circadian clock machinery, how this regulation occurs, and what other possible作者: Foreshadow 時(shí)間: 2025-3-26 13:35 作者: 跳脫衣舞的人 時(shí)間: 2025-3-26 19:24
Sirtuins: A Future Perspective, as well as chronic disease states and metabolism. Interventions targeting human aging and disease are in or on their way to the clinic. Perhaps the most surprising aspect of this is that it all started with yeast aging. Where will it end? One thing seems clear. Our knowledge of mammalian biology ha作者: folliculitis 時(shí)間: 2025-3-26 22:17
Deacetylation by SIRT3 Relieves Inhibition of Mitochondrial Protein Function,s that acetylation suppresses enzymatic activity, and that SIRT3 serves to relieve the suppression. We discuss the possible mechanisms of suppression, and the future studies needed to fully understand the biological role of acetylation and its regulation by the sirtuins.作者: 忍耐 時(shí)間: 2025-3-27 04:35
Sirtuins as Metabolic Modulators of Muscle Plasticity,ment of sirtuin proteins, as metabolic sensors, to regulate these adaptations. Our review will therefore summarize the recent findings related to sirtuin-mediated responses to metabolic stress in skeletal muscle.作者: 歡騰 時(shí)間: 2025-3-27 08:03 作者: Gentry 時(shí)間: 2025-3-27 12:55
1567-2530 discovered food components and/or drugs that target the sirtuins and provide significant health benefits. This book focuses on various aspects of sirtuin biology, from basic biochemistry, via molecular function, to its role in (fighting) human disease.978-94-024-1450-9978-94-024-0962-8Series ISSN 1567-2530 Series E-ISSN 2542-9973 作者: Palpitation 時(shí)間: 2025-3-27 14:53
Diverse Roles for SIRT6 in Mammalian Healthspan and Longevity,glucose intolerance. SIRT6 overexpression results in extended lifespan in male mice, suggesting that SIRT6 may represent a true functional ortholog of yeast Sir2, and supporting an evolutionarily conserved role for sirtuins in longevity.作者: 不近人情 時(shí)間: 2025-3-27 20:51
,Sirtuins in Cancer – Emerging Role as Modulators of Metabolic Reprogramming,hetic pathways. Sirtuin proteins are critical nutrient sensors within the cell that modulate metabolism and have been found to play important roles in rewiring tumor metabolism. In this chapter, we will discuss the role of sirtuins in cancer, especially focusing on how they modulate cancer cell metabolism.作者: 安慰 時(shí)間: 2025-3-28 01:44 作者: 憤憤不平 時(shí)間: 2025-3-28 02:56 作者: 無(wú)脊椎 時(shí)間: 2025-3-28 07:00 作者: confide 時(shí)間: 2025-3-28 10:25 作者: Herd-Immunity 時(shí)間: 2025-3-28 14:54
Characteristics of Flowable Stabilised Earth Concreteo construct load-bearing walls. FEC will be convenient to build monolithic walls with minimum compaction energy. The results on characteristics of FEC such as workability and compressive strength are discussed. The variables considered include clay content of the mix and cement content. The results 作者: 表示向下 時(shí)間: 2025-3-28 19:33
Cable Anti-Gravitator, Electrostatic Levitation and Artificial Gravity,i-gravitator provides a repel (opposed to gravity) force between two bodies by a rotational closed-loop cable. Electrostatic levitation allows people, cars, and tracks to fly over the Earth’s surface. Artificial gravity allows astronauts to work near space ship without leash. Multiple related macro-作者: 故意 時(shí)間: 2025-3-29 02:27 作者: 輕信 時(shí)間: 2025-3-29 03:39
Die schnelle Fourier-Transformation,Algorithmen an. Computer k?nnen mit Hilfe ausgeklügelter Algorithmen Rechnungen bew?ltigen, die sonst endlos lange dauern würden. Auch die schnelle Fourier-Transformation (abgekürzt nach dem englischen FFT = Fast Fourier Transform) ist ein moderner Algorithmus, ja vielleicht sogar der, der die gr??t作者: neutrophils 時(shí)間: 2025-3-29 09:35
Gaining the Edge Through Product-Delivery Services, satisfaction that goes beyond the functionality of their products to include services. This stems from the fact that neither better-built products nor physical production and distribution channels can in themselves create sustainable competitive advantage—they are too easily duplicated, reversed-engineered, and cloned or produced offshore.作者: 小步走路 時(shí)間: 2025-3-29 13:10 作者: ectropion 時(shí)間: 2025-3-29 18:14
Book 2006Latest editionmunity, SECI was a prelude to a broader instrument - the Stability Pact for South Eastern Europe, launched in 1999. The approach was a success! This compendium of documents, agreements, analyses and essays gives a glimpse into decision-making processes and results achieved. .作者: Mundane 時(shí)間: 2025-3-29 21:11 作者: vascular 時(shí)間: 2025-3-30 03:52
n of the RNA over a limited range of concentrations of tamoxifen. The pNR—2 mRNA was measured in breast tumors. The pNR—2 expression was only detected in tumors expressing estrogen receptor mRNA, and pNR—2 expression was associated with response to tamoxifen in a group of patients receiving primary 作者: enterprise 時(shí)間: 2025-3-30 06:17 作者: GENUS 時(shí)間: 2025-3-30 11:38 作者: 釘牢 時(shí)間: 2025-3-30 13:35
https://doi.org/10.1007/978-3-642-92344-9Chemie; Diffusion; Dissoziation; Elektrolyte; Hydrolyse; Kolloide; L?slichkeit; L?sungen; Mikroskopie; Mische作者: 可觸知 時(shí)間: 2025-3-30 20:28
Wafer Temperature Measurement in RTP,stem and derives the missing condition(s) of the leading order system of equations, if any, from the compatibility condition(s) on the next order. Special emphasis is placed on the importance of formulating the correct mathematical model relevant to the physical insight and the understanding of the physical implications.作者: 調(diào)色板 時(shí)間: 2025-3-30 22:59
