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標(biāo)題: Titlebook: Role of Transcription Factors in Gastrointestinal Malignancies; Ganji Purnachandra Nagaraju,Pallaval Veera‘Bramhac Book 2017 Springer Natu [打印本頁(yè)]

作者: 兩邊在擴(kuò)散    時(shí)間: 2025-3-21 17:54
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作者: CURT    時(shí)間: 2025-3-21 22:01

作者: Keshan-disease    時(shí)間: 2025-3-22 03:54

作者: Alpha-Cells    時(shí)間: 2025-3-22 06:29

作者: follicular-unit    時(shí)間: 2025-3-22 11:38

作者: 詩(shī)集    時(shí)間: 2025-3-22 12:54

作者: SSRIS    時(shí)間: 2025-3-22 20:03
A. M. V. N. Prathyusha,Renuka Nawadkar,Pallaval Veera Bramhachari
作者: 描繪    時(shí)間: 2025-3-23 00:39

作者: adj憂郁的    時(shí)間: 2025-3-23 02:31

作者: faultfinder    時(shí)間: 2025-3-23 05:43
AP-1: Its Role in Gastrointestinal Malignancies,1 in cancer appear to rely on composition of AP-1 dimers and type, stage, and genetic basis of cancer. c-Jun protein, one of the subunits of AP-1 up on activation, is expressed primarily at invasive front in carcinomas leading to the proliferation of malignant cells. Thus, c-Jun mainly has oncogenic
作者: 全面    時(shí)間: 2025-3-23 12:33
A Potential Role of Hypoxia-Inducible Factor-1 (HIF-1) in Esophageal Cancer,er types. Considering all parameters, HIF-1 inhibitor could present a potential approach to cancer therapy. This chapter summarizes the potential roles of HIF-1. in cell cycle, proliferation, apoptosis, and metastasis and future perspectives in targeting esophageal cancer for developing novel antica
作者: 咽下    時(shí)間: 2025-3-23 15:18
Role of STAT3 in Gastric Cancer Initiation, Development, and Progression,rolling numerous physiological processes such as cell propagation, differentiation, apoptosis, and angiogenesis by controlling the expression of critical genes in the pathway. Abnormal activation of STAT3 plays a key role in inflammation and transformation in numerous cancers including gastric cance
作者: DOSE    時(shí)間: 2025-3-23 20:16
,Curcumin: Its Role in Regulation of HIF-1α in Gastric Cancer, by downregulating the levels of the oncogene c-Myc expression and thereby hindering the expression of the targeted gene. Curcumin also exhibits antitumor effects under hypoxic conditions by significantly decreasing levels of hypoxia-induced HIF-1α protein, in cancer cells. Furthermore, curcumin eli
作者: geriatrician    時(shí)間: 2025-3-24 02:02
,NF-κB: Its Role in Colorectal Cancer,d promote CRC malignant potential. These NF-κB target genes include those vital to cell cycle regulation, cell proliferation, metastasis, and cell survival. Additionally, activation of NF-κB in both cancerous cells and inflammatory cells and subsequent induction of cytokines/chemokines within the tu
作者: V洗浴    時(shí)間: 2025-3-24 03:42

作者: Respond    時(shí)間: 2025-3-24 06:47
several signaling pathways involved in tumor growth, making them ideal targets for gastrointestinal cancer therapy. In closing, the book provides comprehensive descriptions of the major challenges associated with gastrointestinal cancer therapy..978-981-13-3893-9978-981-10-6728-0
作者: murmur    時(shí)間: 2025-3-24 11:45
Tapan K. Barik,Surya N. Swainie Kapitel über die (Kristall-)Arthropathien leiten zu den degenerativen Gelenk- und Wirbels?ulenerkrankungen über, die einen wesentlichen und zunehmenden Stellenwert in der radiologischen Diagnostik einnehmen. Schlie?lich folgen noch ausführliche Kapitel zu Erkrankungen der Weichteile einschlie?lich ihrer Tumoren. .978-3-540-27612-8
作者: 僵硬    時(shí)間: 2025-3-24 15:16

作者: 淺灘    時(shí)間: 2025-3-24 20:02

作者: Albinism    時(shí)間: 2025-3-25 02:20

作者: Calculus    時(shí)間: 2025-3-25 05:52
Ganji Purnachandra Nagaraju,Subasini Pattnaikie Kapitel über die (Kristall-)Arthropathien leiten zu den degenerativen Gelenk- und Wirbels?ulenerkrankungen über, die einen wesentlichen und zunehmenden Stellenwert in der radiologischen Diagnostik einnehmen. Schlie?lich folgen noch ausführliche Kapitel zu Erkrankungen der Weichteile einschlie?lich ihrer Tumoren. .978-3-540-27612-8
作者: 平常    時(shí)間: 2025-3-25 08:23
Vajravathi Lakkim,Madhava C. Reddy,Durbaka V. R. Prasad,Dakshayani Lomadaie Kapitel über die (Kristall-)Arthropathien leiten zu den degenerativen Gelenk- und Wirbels?ulenerkrankungen über, die einen wesentlichen und zunehmenden Stellenwert in der radiologischen Diagnostik einnehmen. Schlie?lich folgen noch ausführliche Kapitel zu Erkrankungen der Weichteile einschlie?lich ihrer Tumoren. .978-3-540-27612-8
作者: 使堅(jiān)硬    時(shí)間: 2025-3-25 11:58

作者: TOM    時(shí)間: 2025-3-25 17:18
YY1 and KLF4: Their Role in Gastrointestinal Malignancies, and YY1 occupy a central niche and can influence the process of oncogenesis of the various tissues of the GI tract in a major way by being closely associated with several cellular processes such as cell proliferation, differentiation, DNA repair, epigenetic modifications, and apoptosis. Although ev
作者: 乳白光    時(shí)間: 2025-3-25 22:37

作者: 中古    時(shí)間: 2025-3-26 01:51

作者: 綠州    時(shí)間: 2025-3-26 08:09

作者: cylinder    時(shí)間: 2025-3-26 12:04

作者: Callus    時(shí)間: 2025-3-26 16:27
A Potential Role of Hypoxia-Inducible Factor-1 (HIF-1) in Esophageal Cancer,tration in cells and tissues. The protein is a heterodimer which consists of subunit HIF-α and HIF-β. It is an important transcription factor involved in the transcriptional regulation of many genes related to embryonic development, metabolism, cell proliferation, angiogenesis, metastasis, and respo
作者: 毀壞    時(shí)間: 2025-3-26 20:18
Genistein and Its Role in Regulation of AP-1 in Colorectal Cancer,scription factor that regulates many oncogenic transduction pathways. In the current chapter, we discuss the importance of AP-1 on CRC growth and metastasis. Additionally, we discuss the mechanism of genistein, a tyrosine kinase inhibitor, and its effect on CRC treatment.
作者: 無(wú)法破譯    時(shí)間: 2025-3-27 00:03
Role and Regulation of Transcriptional Factors in Gastric Cancer, species induce, amplify, and sustain inflammation (in the lining of the stomach) in the host. Signalling pathways like β-catenin, NF-κB, etc. bring about changes in the genetic material leading to diversification of genetic material. Genetic diversification in oncogenes and tumour suppressor genes
作者: Recessive    時(shí)間: 2025-3-27 04:37
Role of Hypoxia-Inducible Factor (HIF) in the Initiation of Cancer and Its Therapeutic Inhibitors,or (HIF) facilitates the cellular response to hypoxia. HIF, a heterodimer composed of two subunits, the subunit α and subunit β, is involved in several signaling pathways which involves both survival and death pathways, their activation and regulation. HIF is believed to be the best molecular target
作者: 艱苦地移動(dòng)    時(shí)間: 2025-3-27 08:52
Activation of STAT3 in Gastric Cancer Development,and cytokines regulate homeostasis of both epithelial and stromal cells. Deregulation of STAT3 activation is important in the initiation of transformation of various cancers that are epithelial in origin. This chapter mainly focuses on STAT3 activation in gastric cancer and its progression with the
作者: Painstaking    時(shí)間: 2025-3-27 10:38
Role of STAT3 in Gastric Cancer Initiation, Development, and Progression,in terms of manifestation. Annual gastric cancer manifestations are reaching several millions of deaths along with millions of new cases. Gastric cancer which is not detected in the early stages has very poor prognosis, and the 5-year survival rate is only around 20%. Gastric cancer development incl
作者: 合并    時(shí)間: 2025-3-27 15:28

作者: Yag-Capsulotomy    時(shí)間: 2025-3-27 18:35
,Curcumin: Its Role in Regulation of HIF-1α in Gastric Cancer,ic cancer, associated with tumor invasion and metastasis. Under hypoxic conditions, cancer cells start their own adaptive pathways to have a facilitated oxygen and energy supply for survival. In this condition, hypoxia-inducible factors (HIF) such as HIF-1α have a vital role particularly in cellular
作者: institute    時(shí)間: 2025-3-28 01:11

作者: 排他    時(shí)間: 2025-3-28 04:42
Activator Protein-1 Transcription Factors in Pathological Cancers,iption factors driving the progression of cancer, there is still a knowledge gap in the process of better understanding the molecular mechanisms controlled by AP-1 transcription factors during cancer advancement. ., we have evaluated the role of transcription factors which provides new insights into
作者: 發(fā)展    時(shí)間: 2025-3-28 10:01

作者: GUISE    時(shí)間: 2025-3-28 10:51

作者: 鉆孔    時(shí)間: 2025-3-28 15:44

作者: Talkative    時(shí)間: 2025-3-28 20:13
Book 2017mechanism and target definition in drug discovery. Further, it describes the complex issues associated with cancer cell growth and metastasis. The respective chapters provide detailed information on the various types of transcription factors (NF-kB, HIF-1, STAT-3, E2F1, and Sp1) and gastric-associat
作者: 緊張過(guò)度    時(shí)間: 2025-3-28 22:54
YY1 and KLF4: Their Role in Gastrointestinal Malignancies,idence over the years has implicated KLF4 and YY1 in the process of tumorigenesis, significant loopholes still remain. This review is an attempt to evaluate the relative contributions of KLF4 and YY1 to various aspects of GI malignancies.
作者: 參考書目    時(shí)間: 2025-3-29 06:06
,NF-κB Role and Potential Drug Targets in Gastrointestinal Cancer, in several diseases. NF-κB is actively expressed in many cancers and helps in initiations, cell proliferations, and metastasis of different cancers. The present chapter discusses the role of NF-κB in cancer promotion and different drug targets, targeting NF-κB pathway for the treatment of cancers.
作者: 聯(lián)想記憶    時(shí)間: 2025-3-29 10:49
Role and Regulation of Transcriptional Factors in Gastric Cancer,leads to gastric cancer. Transcriptional factors’ role in apoptosis, cell cycle, cell proliferation, and metastasis (adhesion, invasion, migration, angiogenesis) is well known and established. The role and regulation of transcriptional factors in relation to gastric cancer was reviewed.
作者: 古代    時(shí)間: 2025-3-29 13:20
Role of Hypoxia-Inducible Factor (HIF) in the Initiation of Cancer and Its Therapeutic Inhibitors, in the treatment of cancer, and also numerous inhibitors for HIF-1α are available today. This chapter explains the HIF-1α role in cancer and its therapeutic applications that potentially target HIF pathway.
作者: HPA533    時(shí)間: 2025-3-29 17:52
Book 2017, migration, invasion and apoptosis. These transcription factors control the expression of several signaling pathways involved in tumor growth, making them ideal targets for gastrointestinal cancer therapy. In closing, the book provides comprehensive descriptions of the major challenges associated with gastrointestinal cancer therapy..
作者: 魅力    時(shí)間: 2025-3-29 19:53

作者: figure    時(shí)間: 2025-3-30 02:54
Transcription Factors in Gastrointestinal Malignancies,re, targeting these transcriptional factors is an important therapeutic strategy against cancer. In this book, we will discuss some of the important transcriptional factors in depth and further evaluate their role in Gastrointestinal malignancies.
作者: harangue    時(shí)間: 2025-3-30 06:35
Activator Protein-1 Transcription Factors in Pathological Cancers,olled by AP-1 transcription factors during cancer advancement. ., we have evaluated the role of transcription factors which provides new insights into mechanisms of regulation of colorectal cancer by AP-1 family transcription factors.
作者: exercise    時(shí)間: 2025-3-30 08:32
,HIF-1α: Its Role in Metastasis of Oesophageal Malignancy,tumors to hypoxia. Therefore, HIF-1α acts as a promising target in advancement of new therapeutics for oesophagus cancer therapy. Recent developments in regulation of HIF-1α and functional involvement in tumor growth, migration, stemness and drugs affecting HIF-1α expression will be discussed in this review.
作者: Catheter    時(shí)間: 2025-3-30 12:31

作者: EXALT    時(shí)間: 2025-3-30 19:04

作者: Missile    時(shí)間: 2025-3-30 21:25
Transcription Factors and Colorectal Cancer: An Overview,involved in various CRC pathogenesis will be useful in designing novel therapeutic strategies specifically targeting the dysregulated transcription factors. This chapter emphasizes the role of major transcription factors and their dysregulation in CRC.
作者: 拋射物    時(shí)間: 2025-3-31 04:44

作者: liaison    時(shí)間: 2025-3-31 08:58
Genistein and Its Role in Regulation of AP-1 in Colorectal Cancer,scription factor that regulates many oncogenic transduction pathways. In the current chapter, we discuss the importance of AP-1 on CRC growth and metastasis. Additionally, we discuss the mechanism of genistein, a tyrosine kinase inhibitor, and its effect on CRC treatment.
作者: Medicare    時(shí)間: 2025-3-31 11:55
,Curcumin Suppresses Colorectal Cancer Growth and Metastasis by Inhibiting NF-κB Activity,ncer’s ability to activate major transcription factors such as NF-κB. Curcumin, a phytochemical, is known to downregulate NF-κB signaling in CRC cell lines and to exhibit anticarcinogenic properties. Therefore, curcumin and its analogues are novel therapeutic agents that could be used in the treatment of CRC growth and metastasis.
作者: 轉(zhuǎn)換    時(shí)間: 2025-3-31 16:31
978-981-13-3893-9Springer Nature Singapore Pte Ltd 2017
作者: entreat    時(shí)間: 2025-3-31 18:05





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