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標(biāo)題: Titlebook: Role of Proteases in Cellular Dysfunction; Naranjan S. Dhalla,Sajal Chakraborti Book 2014 Springer Science+Business Media New York 2014 an [打印本頁]

作者: 漠不關(guān)心    時(shí)間: 2025-3-21 18:26
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作者: 拱形面包    時(shí)間: 2025-3-21 22:47
Pushpak Bhattacharjee,Minakshi Mazumdar,Deblina Guha,Gaurisankar Sa
作者: 刪減    時(shí)間: 2025-3-22 04:09

作者: Rotator-Cuff    時(shí)間: 2025-3-22 05:12
Role of Calpain in Immunobiology of Neurodegenerative Diseasesof the CNS. Recently, there is a great interest in developing water-soluble and cell-permeable small molecule inhibitors of calpain for treatment of MS and other neurodegenerative diseases. Although exciting results are being reported showing efficacy of experimental calpain inhibitors in preclinica
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Matrix Metalloproteinase and Its Inhibitors in Cancer Progression 20 years, intensive drug discovery programs are carried out in many clinical trials of matrix metalloproteinase inhibitors (MMPIs) for cancer therapy. Number of MMP inhibitors (MMPIs) have been devolved for the cancer treatment. However, their efficacy and action have not been confirmed, and more d
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作者: refine    時(shí)間: 2025-3-23 11:42
A Disintegrin and Metalloproteinase-12 as a New Target for Cancer Treatmentore, a statistical correlation between the urinary levels of ADAM-12 in breast and bladder cancer patients and cancer progression has been found. These results suggested that ADAM-12 could be used as a diagnostic marker. In addition to cancers, increase of ADAM-12 expression is linked to the pathoge
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作者: 獸皮    時(shí)間: 2025-3-23 20:11
Matrix Metalloproteinases and Hypertension kidney. MMP inhibition appears to be a relevant target for newer pharmacological intervention in hypertension. Doxycycline is the MMP inhibitor most widely used in cell cultures, animal studies on hypertension, and is a drug approved for commercial use for periodontal disease in the United States.
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作者: 大包裹    時(shí)間: 2025-3-24 06:26
Book 2014 three parts in specified topics based on current literatures for a better understanding for the readers with respect to their subject-wise interests. The first section of this book covers a brief idea about the neuronal disorders and the involvement of proteases such as calpains, caspases and matri
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作者: 空洞    時(shí)間: 2025-3-24 17:03
Nicole Trager,Azizul Haque,Swapan K. Ray,Arabinda Das,Naren L. Banikwas mehr Breitenwirkung, nicht zuletzt, damit eine" wesen-tliche" T?tigkeit der Banken - das Kreditgesch?ft, was ja nicht umsonst im Begriff "Kreditinstitute" zum Ausdruck kommt - einem gr??eren Verst?ndnis auch in der ?ffentlichkeit be- gegnen m?ge.
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作者: 結(jié)合    時(shí)間: 2025-3-25 02:29
Alakananda Goswami,Prosenjit Sen,Kuladip Jana,Sanghamitra Rahae den Schaden tr?gt, der der Bank daraus entstehen sollte, da? sie von einem eintretenden Mangel in der Gesch?ftsf?higkeit des Kunden oder seines Vertreters unverschuldet keine Kenntnis erlangt, bietet keinen vollst?ndigen Schutz für die Bank. Diese Bestimmung greift nach der Rechtsprechung nur dann
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作者: preeclampsia    時(shí)間: 2025-3-25 13:29
Avi Bar,Irit Shoval,Efrat Monsonego-Ornan,Dalit Sela-Donenfeld absolute Gew?hr für die vereinbarungsgem??e Zinszahlung und Tilgung des Kredits in Form einer Sicherheit im Rechtssinne hinzukommen, die für den Fall einer künftigen Zahlungsunf?higkeit oder auch nur Zahlungsunwilligkeit des Kreditnehmers die Erfüllung der schuldnerischen Verpflichtung gegenüber de
作者: 陰險(xiǎn)    時(shí)間: 2025-3-25 16:55
Schaden tr?gt, der der Bank daraus entstehen sollte, da? sie von einem eintretenden Mangel in der Gesch?ftsf?higkeit des Kunden oder seines Vertreters unverschuldet keine Kenntnis erlangt, bietet keinen vollst?ndigen Schutz für die Bank. Diese Bestimmung greift nach der Rechtsprechung nur dann ein,
作者: 躲債    時(shí)間: 2025-3-25 22:53

作者: LEVY    時(shí)間: 2025-3-26 01:33

作者: exophthalmos    時(shí)間: 2025-3-26 06:55
ettbewerbsf?higen Tagebaubetrieb zu erschlie?en. Die Umstellung auf den Tagebaubetrieb verschaffte der Braunkohlenindustrie einen ungeahnten Aufschwung; sie verlangte aber mit der Zeit eine immer weiter fortschreitende Vergr??erung und Vervollkommnung der Eimerkettenbagger, die heute in gr??tem Umfa
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作者: 枯萎將要    時(shí)間: 2025-3-26 14:17
Nicole Paland,Bianca Fuhrmann. Bei Betonbauten lassen sich die durch Güteprüfungen des Betons (s. § 279) gewonnenen Ergebnisse auch nicht ohne weiteres auf die Beanspruchungen im Bauwerk übertragen. Auch versagen oft wegen der Eigenart des Betonmaterials die üblichen Berechnungsverfahren, und alle diese Umst?nde dr?ngen dazu,
作者: faultfinder    時(shí)間: 2025-3-26 18:23

作者: 存在主義    時(shí)間: 2025-3-26 23:59
Erin R. Mandel,Cassandra Uchida,Tara L. Haasn. Bei Betonbauten lassen sich die durch Güteprüfungen des Betons (s. § 279) gewonnenen Ergebnisse auch nicht ohne weiteres auf die Beanspruchungen im Bauwerk übertragen. Auch versagen oft wegen der Eigenart des Betonmaterials die üblichen Berechnungsverfahren, und alle diese Umst?nde dr?ngen dazu,
作者: JOT    時(shí)間: 2025-3-27 04:17

作者: 紳士    時(shí)間: 2025-3-27 06:54
978-1-4939-4634-1Springer Science+Business Media New York 2014
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作者: ELUC    時(shí)間: 2025-3-27 15:57

作者: 生命層    時(shí)間: 2025-3-27 19:38
Advances in Biochemistry in Health and Diseasehttp://image.papertrans.cn/r/image/831548.jpg
作者: congenial    時(shí)間: 2025-3-28 00:12
https://doi.org/10.1007/978-1-4614-9099-9antiproteases; cancer; cardiovascular diseases; cell dysfunction; diabetes; proteases; Proteomics; Receptor
作者: Feckless    時(shí)間: 2025-3-28 03:14

作者: 愉快么    時(shí)間: 2025-3-28 08:09

作者: abysmal    時(shí)間: 2025-3-28 11:06
Proteases and Cancer Developmentanges of these proteases affect various aspects of cancer development, including transformation, apoptosis, invasion, and metastasis of cancer cells. Targeting these proteases is becoming an important approach to cancer treatment.
作者: 痛得哭了    時(shí)間: 2025-3-28 18:02
Book 2014 a variety of biological functions ranging from digestion, fertilization, development to senescence and death. Under physiological conditions the ability of proteases is regulated by endogenous inhibitors. However, when the activity of proteases is not regulated appropriately, disease processes can
作者: squander    時(shí)間: 2025-3-28 22:35
2512-2142 nction, with strong emphasis on identifying proteases and th.It is now well known that proteases are found everywhere, in viruses and bacteria as well as in all human, animal and plant cells, and play a role in a variety of biological functions ranging from digestion, fertilization, development to s
作者: 不如樂死去    時(shí)間: 2025-3-29 01:32
Role of Calpain in Immunobiology of Neurodegenerative Diseases the central nervous system (CNS). Studies from our laboratory and other laboratories clearly indicate that calpain plays crucial roles in pro-inflammatory immune responses to perpetuate inflammation in multiple sclerosis (MS), which is a demyelinative and neurodegenerative disease of the CNS, and e
作者: 曲解    時(shí)間: 2025-3-29 04:04

作者: Assignment    時(shí)間: 2025-3-29 10:20

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作者: 有花    時(shí)間: 2025-3-29 20:43

作者: Confirm    時(shí)間: 2025-3-30 03:50
Proteases and Cancer Developmente development of cancer are discussed in this chapter. As mitochondrial proteases, HtrA2/Omi regulates inhibitors of apoptosis proteins, while Lon protease degrades misfolded proteins and maintains the stability of the mitochondrial genome. Caspases are closely interconnected with mitochondria in ap
作者: RODE    時(shí)間: 2025-3-30 07:46

作者: Pigeon    時(shí)間: 2025-3-30 09:07
Ubiquitin–Proteasome System in the Hallmarks of Cancercated in the regulation of various biological and pathological phenomena. Malignant cells utilize modified ubiquitination to augment or attenuate signaling pathways on the basis of whether the outcome of this signaling is conducive or not for tumor growth and survival. Hence, there lies a necessity
作者: ADAGE    時(shí)間: 2025-3-30 14:22

作者: 折磨    時(shí)間: 2025-3-30 19:38

作者: agitate    時(shí)間: 2025-3-31 00:27
Proteases and Their Role in Drug Development with an Emphasis in Cancertion by regulating the activities of growth factors/cytokines and signalling receptors, as well as the composition of the extracellular matrix, thereby suppressing cell death pathways and activating cell survival pathways. With strong evidence of protease involvement in cancer, proteases serve an im
作者: Blood-Clot    時(shí)間: 2025-3-31 01:00
Role of Matrix Metalloproteinases in Atherosclerosisinstability. Proposed roles for MMPs included matrix degradation but also regulation of the proliferation, migration and apoptosis of monocytes, macrophages and vascular smooth muscle cells. Accordingly, in vitro and in vivo studies have demonstrated that individual MMPs are utilised by distinct cel
作者: 館長    時(shí)間: 2025-3-31 08:30
The Importance of the Urokinase-Type Plasminogen Activator and Its Receptor for the Development and iated with several acute and chronic pathologic conditions. uPA mediates extracellular matrix (ECM) degradation and plays a pivotal role in cell adhesion, migration, and proliferation during tissue remodeling. On the cell surface, uPA binds with high affinity to its receptor, the uPAR, providing a s
作者: ALOFT    時(shí)間: 2025-3-31 10:21

作者: minimal    時(shí)間: 2025-3-31 15:38
Regulation of Proteolysis in Vascular Remodelingycans, and water. Matrix–cell adhesion provides essential cell survival cues and the matrix sequesters various growth factors that can regulate the behavior of adjacent cells. However, the matrix, and in particular, the basement membrane, presents a confining barrier that limits vascular cell moveme
作者: 比目魚    時(shí)間: 2025-3-31 18:09





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