標(biāo)題: Titlebook: Reviews on New Drug Targets in Age-Related Disorders; Part II Paul C. Guest Book 2021 The Editor(s) (if applicable) and The Author(s), unde [打印本頁] 作者: Flexible 時(shí)間: 2025-3-21 18:55
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書目名稱Reviews on New Drug Targets in Age-Related Disorders讀者反饋
書目名稱Reviews on New Drug Targets in Age-Related Disorders讀者反饋學(xué)科排名
作者: Ascribe 時(shí)間: 2025-3-21 23:51
Targeting Cancer Metabolism and Current Anti-Cancer Drugs,i-cancer drugs. It has become apparent that metabolic flexibility allows cancer cells to survive during high anabolic demand or the depletion of nutrients and oxygen. Cancers can reprogram their metabolism to the microenvironments by increasing aerobic glycolysis to maximize ATP production, increasi作者: cogent 時(shí)間: 2025-3-22 04:05 作者: 凹室 時(shí)間: 2025-3-22 05:00
,Parkinson’s Disease and Impairment in Mitochondrial Metabolism: A Pathognomic Signature,ain complexes and other assisting proteins, accumulation of intracellular reactive oxygen species, an imbalance in cellular calcium transport, or the presence of organic pollutants, high fat-ketogenic diets or toxins, and advancing age can result in complex disorders, including cancer, metabolic dis作者: Petechiae 時(shí)間: 2025-3-22 10:17
Targeted Treatment of Age-Related Fibromyalgia with Supplemental Coenzyme Q10, implicated in the pathophysiology of this disorder. Treatment generally involves physiotherapy, anticonvulsants, and antidepressant therapy; however, the symptomatic relief conferred by these treatments can be very variable, and there is a need for additional therapeutic strategies. One such treatm作者: candle 時(shí)間: 2025-3-22 16:57 作者: 漂泊 時(shí)間: 2025-3-22 19:36
Multifaceted Roles of Long Non-coding RNAs in Head and Neck Cancer,like microRNAs (miRNAs), long ncRNAs (lncRNAs) are not confined to a single mechanism of action but have a large and diverse role in biological processes as they can function as transcription regulators, decoys, scaffolds, and enhancer RNAs. Currently, many lncRNA molecules are under investigation f作者: Anthrp 時(shí)間: 2025-3-22 22:53
A Systematic Review on the Genotoxic Effects of Selective Serotonin Reuptake Inhibitors,ated with several medical comorbidities often linked with aging, such as dementia, type II diabetes, cardiovascular and cerebrovascular diseases, as well as metabolic syndrome. There are a variety of medications available for depression treatment. Selective serotonin reuptake inhibitors (SSRIs) are 作者: gangrene 時(shí)間: 2025-3-23 02:34
Toward a New Era for the Management of Circulating Tumor Cells,s, and lead to the formation of metastases. The first description of CTCs dates back to 1869 when Thomas Ashworth recognized malignant cells similar to the ones of the primary tumor in the blood vessels of an autopsied patient with metastatic cancer. Currently, CTCs have been identified in various t作者: Parley 時(shí)間: 2025-3-23 08:16 作者: BLOT 時(shí)間: 2025-3-23 10:12
Aspirin as a Potential Geroprotector: Experimental Data and Clinical Evidence, physical function and higher risks of age-related diseases. The use of anti-aging drugs for disease prevention has become a high priority for science and is a new biomedicine trend. Geroprotectors are compounds which slow aging and increase lifespan of the organism in question. The common painkille作者: Locale 時(shí)間: 2025-3-23 16:17
Targeting Stem Cells in Chronic Inflammatory Diseases,flammation and oxidative stress-induced cellular senescence alter the immunomodulatory ability of MSCs and hamper their pro-regenerative function, which in turn leads to an increase in disease severity, maladaptive tissue damage and the development of comorbidities. Targeting stem/progenitor cells t作者: GOUGE 時(shí)間: 2025-3-23 20:38
,Therapeutic Strategies and Nano-Drug Delivery Applications in Management of Aging Alzheimer’s Disealy suppress symptoms or delay further deterioration but do not address the cause of the disease. In spite of screening numerous drug candidates against various molecular targets of AD, only a few candidates, such as acetylcholinesterase inhibitors, are currently utilized as an effective clinical the作者: irreparable 時(shí)間: 2025-3-23 22:38
Psychometric Evaluation of Stress in 17,414 Critical Care Unit Nurses: Effects of Age, Gender, and ions that are often associated with their profession. The severity of stress can be influenced by a number of factors such as age, seniority gender, family status, and position in the wards. Thus, it is important to monitor signs of stress and other psychiatric symptoms in order to understand the me作者: Prosaic 時(shí)間: 2025-3-24 04:11 作者: 出沒 時(shí)間: 2025-3-24 08:15 作者: 摻假 時(shí)間: 2025-3-24 12:48 作者: Infuriate 時(shí)間: 2025-3-24 17:49 作者: Diskectomy 時(shí)間: 2025-3-24 19:52 作者: Cholesterol 時(shí)間: 2025-3-25 01:44 作者: Cabg318 時(shí)間: 2025-3-25 06:44 作者: 過分 時(shí)間: 2025-3-25 10:13 作者: 約會(huì) 時(shí)間: 2025-3-25 12:24 作者: 熱情的我 時(shí)間: 2025-3-25 16:45 作者: orthopedist 時(shí)間: 2025-3-25 21:31
Proteomics for Target Identification in Psychiatric and Neurodegenerative Disorders,l fluid (CSF) or blood of patients. These studies have identified possible therapeutic targets and disease biomarkers. Further studies including target validation, the use of large sample sizes, and the integration of omics findings with bioinformatics tools are required to provide a better comprehension of pharmacological targets.作者: gain631 時(shí)間: 2025-3-26 03:47 作者: 永久 時(shí)間: 2025-3-26 07:08 作者: 裂隙 時(shí)間: 2025-3-26 10:53
,Therapeutic Strategies and Nano-Drug Delivery Applications in Management of Aging Alzheimer’s Disearapy. Currently, nano-based therapies can make a difference, providing new therapeutic options by helping drugs to cross the blood-brain barrier and enter the brain more effectively. The main aim of this review was to highlight advances in research on the development of nano-based therapeutics for improved treatment of AD.作者: Truculent 時(shí)間: 2025-3-26 15:41 作者: 預(yù)感 時(shí)間: 2025-3-26 17:14
Paul C. GuestDescribes potential novel drug targets for age-related disorders.Reviews studies and current research on age-related disorders worldwide.Discusses developments for new therapeutic approaches to age-re作者: flourish 時(shí)間: 2025-3-26 21:08 作者: 稀釋前 時(shí)間: 2025-3-27 02:18 作者: Incorporate 時(shí)間: 2025-3-27 06:47 作者: graphy 時(shí)間: 2025-3-27 12:54
Reviews on New Drug Targets in Age-Related Disorders978-3-030-55035-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: cancellous-bone 時(shí)間: 2025-3-27 14:09
Witchuda Sukjoi,Jarunya Ngamkham,Paul V. Attwood,Sarawut Jitrapakdeee Czech Communist Party. At the Congress the KKE leader met Togliatti, Thorez and Dimitrov and discussed with them the situation in Greece. While the Italian and French communist leaders advised Zachariadis against an armed conflict,. Dimitrov seems to have supported a ‘gradual escalation of the arm作者: LEER 時(shí)間: 2025-3-27 21:41
Yunes Panahi,Amir Hossein Mohammadzadeh,Behzad Behnam,Hossein M. Orafai,Tannaz Jamialahmadi,Amirhosse Czech Communist Party. At the Congress the KKE leader met Togliatti, Thorez and Dimitrov and discussed with them the situation in Greece. While the Italian and French communist leaders advised Zachariadis against an armed conflict,. Dimitrov seems to have supported a ‘gradual escalation of the arm作者: spinal-stenosis 時(shí)間: 2025-3-27 23:24
Biswadeep Das,Sriya Priyadarshini Dash,Swabhiman Mohanty,Paritosh Patele Resistance and the Civil War. In so doing it has tried to avoid the obvious error, so common in Greek historiography of the Left, of ascribing primary responsibility for the engagement and the defeat of the KKE in the ‘December Events’ and the civil war to the ‘imperialist designs’ of the British 作者: 案發(fā)地點(diǎn) 時(shí)間: 2025-3-28 04:01
Iain P. Hargreaves,David Mantle establishment to provide aid to Greece and intervene there, because the ‘fall of Greece will contaminate the whole of Europe and the Middle East’ benefitting the Eastern Soviet enemy. Today, Greece’s fall is also imminent challenging the survival of the entire European architecture whereas the enti作者: anaerobic 時(shí)間: 2025-3-28 07:11
Hadi Atabati,Esmaeil Yazdanpanah,Hamed Mortazavi,Saeed Gharibian bajestani,Amir Raoofi,Seyed-Alirezaty/overproduction’ caused, among others, by ‘uneven development’. Laggards, such as West Germany and Japan whose economies had been destroyed by World War II, managed not only to catch-up with the USA but also to out-compete it, the result being a fall in profitability from which the heartland has n作者: 努力趕上 時(shí)間: 2025-3-28 11:00 作者: Mast-Cell 時(shí)間: 2025-3-28 15:53 作者: 古董 時(shí)間: 2025-3-28 20:44
Marisol Miranda Galvis,Celeste Sánchez Romero,Thiago Oliveira Bueno,Yong Tengof a preaccession period and instructed it to prepare the way, together with COREPER, for the opening of negotiations as soon as possible. The formal opening of talks took place on 27 July 1976, nearly six months later. The main reasons for the Community’s procrastination arose from internal Communi作者: 細(xì)胞 時(shí)間: 2025-3-29 01:40 作者: appall 時(shí)間: 2025-3-29 04:22 作者: 寬大 時(shí)間: 2025-3-29 09:44
Mari van de Vyver,Yigael S. L. Powrie,Carine Smithne of this corresponds to reality. On the contrary, the Greek crisis results from a convergence of two factors. On the one hand, the growth model that had been in application up to that point (relatively low wages, strong ship-owning capital, a developed banking sector, tourism, European subsidies) 作者: Petechiae 時(shí)間: 2025-3-29 15:00 作者: MOAT 時(shí)間: 2025-3-29 18:03
Mohammad Asghari Jafarabadi,Amir Vahedian-Azimi,Farshid Rahimibashar,Paul C. Guest,Leila Karimi,Amir system. This was largely inevitable given the immediate postwar circumstances. Bank assets were depleted, no new savings were flowing in, and hyperinflation remained persistent until 1951. Greece had been left in ruins, and reconstruction required new investment (frozen for nearly a decade), extens作者: gain631 時(shí)間: 2025-3-29 22:49
Umut Cagin1974. The improvement of Turkish-Soviet relations since the mid-1960s and the dramatic deterioration of the Greek-Turkish relations, while Greece was not a member of the NATO military structure, were the main drivers of the new foreign policy course. Greece’s withdrawal from the NATO integrated mili作者: 埋葬 時(shí)間: 2025-3-30 00:30 作者: Venules 時(shí)間: 2025-3-30 06:36
André S. L. M. Antunes,Valéria de Almeida,Fernanda Crunfli,Victor C. Carregari,Daniel Martins-de-Soun exacerbation with some of the more dogmatic proponents of the free market economy. During the 1980s, Reaganomics in the United States and Thatcherism in the United Kingdom not only celebrated greed and individualism, it told us that it was through greed that the economy worked best. We were told t作者: idiopathic 時(shí)間: 2025-3-30 09:34 作者: 冷漠 時(shí)間: 2025-3-30 14:29
Immunoregulatory Effects of Tolerogenic Probiotics in Multiple Sclerosis,s, through induction of regulatory T cells and increase of anti-inflammatory cytokines, play a crucial role in controlling inflammation and maintaining tolerance and hemostasis. Therefore, probiotics can be considered as a preventive or therapeutic tool in MS. In the present review, we focus on the 作者: 金哥占卜者 時(shí)間: 2025-3-30 19:09
A Systematic Review on the Genotoxic Effects of Selective Serotonin Reuptake Inhibitors,bMed, Scopus, Embase, and Web of Science to find the published documents on SSRIs and their genotoxic effects from January 1990 to November 2019. After the removal of 203 duplicate articles, 385 articles were screened and 167 articles met the inclusion criteria and qualified for evaluation of their 作者: Omnipotent 時(shí)間: 2025-3-30 22:47
