標(biāo)題: Titlebook: Retroviral Proteases; Control of maturatio Laurence H. Pearl Textbook 1990Latest edition Macmillan Publishers Limited 1990 AIDS.biology.evo [打印本頁] 作者: 他剪短 時(shí)間: 2025-3-21 19:41
書目名稱Retroviral Proteases影響因子(影響力)
書目名稱Retroviral Proteases影響因子(影響力)學(xué)科排名
書目名稱Retroviral Proteases網(wǎng)絡(luò)公開度
書目名稱Retroviral Proteases網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Retroviral Proteases被引頻次
書目名稱Retroviral Proteases被引頻次學(xué)科排名
書目名稱Retroviral Proteases年度引用
書目名稱Retroviral Proteases年度引用學(xué)科排名
書目名稱Retroviral Proteases讀者反饋
書目名稱Retroviral Proteases讀者反饋學(xué)科排名
作者: 潔凈 時(shí)間: 2025-3-21 22:57
Characterisation and Inhibition of the Retroviral HIV-Protease,particles (Kohl, ., 1988). Retroviral proteases appear to have a highly specific relation to their virus encoded substrate (Dittmar and Moelling, 1978; Khan and Stephenson, 1979; Yoshinaka ., 1985; Kr?usslich and von der Helm, 1987). Examination of the amino acid sequences of retroviral proteases in作者: 巨碩 時(shí)間: 2025-3-22 02:58
Cleavage of RT/RNase H by HIV-1 Protease and Analysis of Substrate Cleavage Sites ,ge of denatured ovalbumin, of the MS2. fusion protein or synthetic peptides. Several synthetic peptides representing various poten tial protease cleavage sites and modifications thereof were analyzed . . for their efficiency of cleavage by the protease. One synthetic peptide representing the natural作者: 咽下 時(shí)間: 2025-3-22 05:58 作者: Brocas-Area 時(shí)間: 2025-3-22 11:38
Functional Characterisation of HIV-1 , Fusion Protein,ypeptide composed of a C-terminal-truncated . peptide and the entire . peptide. The second stage involves the proteolytic processing of this fusion protein to generate mature structural and functional viral components (Debouck ., 1987; Lillehoj ., 1988). An HIV-specific protease cleaves the fusion p作者: 捐助 時(shí)間: 2025-3-22 13:50
Biosynthesis and Processing of the , and , Polyproteins of Human Immunodeficiency Virus Type 1 in , (Farmerie ., 1987; Graves ., 1988). There are at least seven protease cleavage sites in the . and . polyprotein precursors (Darke ., 1988), as depicted in Figure 1. The numbering of amino acid residues at the cleavage sites is based on the amino acid sequence predicted from the nucleotide sequence 作者: 釘牢 時(shí)間: 2025-3-22 18:21 作者: Concerto 時(shí)間: 2025-3-23 00:52
Expression of HIV-1 , and , Gene Products using Recombinant Baculoviruses,oduce some ten different recombinant baculoviruses expressing various gene products encoded by both HIV-1 and HIV-2. Here we describe four of these recombinant viruses that produce products encoded by the gag and . genes of HIV-1. We show that a feature of gag and . translation in HIV-1 infected cel作者: abreast 時(shí)間: 2025-3-23 03:01 作者: 閃光你我 時(shí)間: 2025-3-23 06:36
Mei-Huei T. Lai,Albert G. Dee,Peter H. Zervos,William F. Heath Jr,Maurice E. Scheetz作者: DNR215 時(shí)間: 2025-3-23 11:02
Andrew Wilderspin,Duncan Gaskin,Risto Lapatto,Tom Blundell,Andrew Hemmings,John Overington,Jim Pitts作者: oxidize 時(shí)間: 2025-3-23 15:12
conomies share with other types of developing countries, differ by degree between the different types of developing countries. What sets small developing economies apart and defines them as a distinct genre of developing country is the combination of characteristics and the degree or extent to which作者: 占卜者 時(shí)間: 2025-3-23 21:24 作者: 大猩猩 時(shí)間: 2025-3-24 01:10
Christine Debouck,Ingrid C. Deckman,Stephan K. Grant,Robert J. Craig,Michael L. Moorehe Jamaican-born Hopkinson has lived since 1977), a cityscape abandoned by governmental authority and private interest alike. The Burn, as this lawless core is called, is overseen by the gangster Rudy, whose authoritarian capacity for violence is achieved through the evil misuse of Afro-Caribbean Ob作者: Ancillary 時(shí)間: 2025-3-24 05:02 作者: contradict 時(shí)間: 2025-3-24 06:39
Yoshiyuki Yoshinaka,Iyoko Katoh,Kohei Odany as 60,000 dead or ‘disappeared’, In addition, the south also suffered constant spillover effects of the war in the north-east and was subject to a regular stream of devastating bomb explosions, suicide attacks, and assassinations that maintained a constant atmosphere of tension and fear.作者: 跟隨 時(shí)間: 2025-3-24 14:02
Alan J. Kingsman,Wilma Wilson,Susan M. Kingsmanny as 60,000 dead or ‘disappeared’, In addition, the south also suffered constant spillover effects of the war in the north-east and was subject to a regular stream of devastating bomb explosions, suicide attacks, and assassinations that maintained a constant atmosphere of tension and fear.作者: VOK 時(shí)間: 2025-3-24 18:56 作者: ovation 時(shí)間: 2025-3-24 22:30 作者: GLARE 時(shí)間: 2025-3-25 00:35 作者: 解開 時(shí)間: 2025-3-25 06:39
M. M. Roberts,S. Oroszlanstatus markers in the interplay between critical attention and production commentary, it shows a near-complete convergence of these status markers in its non-verbalized production imagery. This allows wider insights in how status is communicated in open and veiled manners.作者: 護(hù)航艦 時(shí)間: 2025-3-25 09:00 作者: arbiter 時(shí)間: 2025-3-25 12:47 作者: 清楚說話 時(shí)間: 2025-3-25 19:03
he choice for expanding the EU instead of first deepening cooperation before expanding, so creating an institutional trap. All these discussions were taking place in the context of a mood of victory — that is the victory of ‘markets’ over the ‘state’. Market fundamentalism spread quickly after the d作者: obsolete 時(shí)間: 2025-3-25 22:46
Macmillan Publishers Limited 1990作者: 仲裁者 時(shí)間: 2025-3-26 01:23
http://image.papertrans.cn/r/image/829284.jpg作者: 信條 時(shí)間: 2025-3-26 05:23 作者: 粉筆 時(shí)間: 2025-3-26 10:55 作者: angiography 時(shí)間: 2025-3-26 15:01 作者: 糾纏,纏繞 時(shí)間: 2025-3-26 19:35
Laurence H. Pearlore the issue for ever country is how to mediate the encounter with globalization in a manner that can benefit their economic growth and promote their economic development. Globalization poses both challenges and opportunities for all countries, large and small, developed and developing. To seize th作者: Locale 時(shí)間: 2025-3-26 21:04
Christine Debouck,Ingrid C. Deckman,Stephan K. Grant,Robert J. Craig,Michael L. Moores, from the millennial vantage of the system’s quarter-century maturation, a critical schematization more directly rooted in a lived experience of place. Notable for its novel injection of Afro-Caribbean mythology into science fiction (SF), Hopkinson’s work is motivated by a dialectical formal logic作者: 到婚嫁年齡 時(shí)間: 2025-3-27 04:12 作者: transplantation 時(shí)間: 2025-3-27 05:46
Yoshiyuki Yoshinaka,Iyoko Katoh,Kohei Odaotagonists.. Over this period, the war claimed over 65,000 lives, and had a particularly devastating effect on the civilian population of the north-east, most of whom lived through extended periods of acute physical and economic insecurity, and suffered repeated episodes of dislocation. At its peak 作者: 形上升才刺激 時(shí)間: 2025-3-27 12:40
Alan J. Kingsman,Wilma Wilson,Susan M. Kingsmanotagonists.. Over this period, the war claimed over 65,000 lives, and had a particularly devastating effect on the civilian population of the north-east, most of whom lived through extended periods of acute physical and economic insecurity, and suffered repeated episodes of dislocation. At its peak 作者: jocular 時(shí)間: 2025-3-27 15:34 作者: vascular 時(shí)間: 2025-3-27 19:07
Helen R. Mills,Hilary A. Overton,Ian M. Jonesints out in her opening chapter women make up about 70 percent of the poor globally, the aggregate number of maternal deaths has increased to around 600,000 annually, and women now constitute the majority of those infected by HIV. A recent overview of the intersections of gender, health, and equity 作者: POLYP 時(shí)間: 2025-3-28 01:32
Sung Rhee,Eric Hunter00 informants over ten years, I analyze how food, particularly seafood, is used to signify intersectarian divisions in Islam. I argue that?the local peoples’ understanding and interpretations of rules regarding lawful and forbidden seafood in Muslim society in southern Thailand may provide a lens in作者: effrontery 時(shí)間: 2025-3-28 03:46 作者: TRUST 時(shí)間: 2025-3-28 07:03
Ronald Luftig,Kazuyoshi Ikuta,Ming Bu,Peter Calkins00 informants over ten years, I analyze how food, particularly seafood, is used to signify intersectarian divisions in Islam. I argue that?the local peoples’ understanding and interpretations of rules regarding lawful and forbidden seafood in Muslim society in southern Thailand may provide a lens in作者: orient 時(shí)間: 2025-3-28 10:46
Stefan H?glund,Lars-G?ran ?fverstedt,?sa Nilsson,Muhsin ?zel,Thorsten Winkel,Ulf Skoglund,Hans Gelde00 informants over ten years, I analyze how food, particularly seafood, is used to signify intersectarian divisions in Islam. I argue that?the local peoples’ understanding and interpretations of rules regarding lawful and forbidden seafood in Muslim society in southern Thailand may provide a lens in作者: 前面 時(shí)間: 2025-3-28 15:32
Hans R. Gelderblom,Preston A. Marx,Muhsin ?zel,Dirk Gheysen,Robert J. Munn,Kenneth I. Joy,Georg Paulal mediazation impact on processes of negotiating contempora.This innovative volume explores the link between local and regional eating cultures and their mediatization via transnational TV cooking shows, glocal food advertising and social media transfer of recipes. Pursuing a global and interdiscip作者: BUOY 時(shí)間: 2025-3-28 21:17
is. In Maastricht (the Netherlands) the monetary union was agreed. The negotiations for the Maastricht Treaty took place during upheaval in Central and Eastern Europe when the divide between Eastern and Western Europe was suddenly lifted, and the EU was faced with the historic challenge of uniting E作者: GUEER 時(shí)間: 2025-3-28 23:58
Retroviral Protease: Substrate Specificity and Inhibitors, genomes encode proteinases. The enzymes work as a processing enzyme which cleaves viral polyprotein precursors into mature components. The precursor processing is essential for production of biologically active virus particles (Klausslich and Wimmer, 1988).作者: MURAL 時(shí)間: 2025-3-29 03:12
Morphogenesis of Retroviruses: A Complex Role for the Matrix (MA) Protein in Assembly, Stability anprotein core composed of genomic RNA and structural protein subunits (Nermut ., 1972; Marx ., 1988). The morphology of the core is somewhat virus specific and may be spherical (Rous sarcoma virus, RSV), rod-shaped (Mason-Pfizer monkey virus, M-PMV) or cone-shaped (human immunodeficiency virus, HIV) in electron micrographs.作者: 護(hù)身符 時(shí)間: 2025-3-29 07:26
Morphogenesis, Maturation and Fine Structure of Lentiviruses,ed proteins (Desrosiers ., 1989). Serological cross-reactivities localized mainly to the viral core, but also to the envelope, have been described for HIV and EIAV (Montagnier ., 1984; Montelaro ., 1988; Schneider ., 1986, 1987).作者: 卜聞 時(shí)間: 2025-3-29 12:42 作者: somnambulism 時(shí)間: 2025-3-29 15:54 作者: Respond 時(shí)間: 2025-3-29 20:24
The HIV-1 Aspartyl Protease: Maturation and Substrate Specificity, case of HIV-1 (Rey ., 1987; Jacks ., 1988). Experimental evidence strongly suggests that HIV-1 viral particles initially bud out of the host cell with an immature structure and composition, containing unprocessed PrSSgag and Pr160gag-Pol polyproteins (Hockley . ., 1988; Gottlinger ., 1989, Peng ., 作者: OUTRE 時(shí)間: 2025-3-30 02:39
Cleavage of RT/RNase H by HIV-1 Protease and Analysis of Substrate Cleavage Sites ,, the p32 endonuclease and the p9 protease. The partially purified protease generates . from the p66 molecule a p66/p51 heterodimer, typical of the normally observed RT/RNase H, and a p15 carboxyterminal fragment. A synthetic peptide AETF’YVD derived from the p51/p15 junction is cleaved by the prote作者: verdict 時(shí)間: 2025-3-30 04:30
Retroviral Protease: Substrate Specificity and Inhibitors,nthesized as polyprotein precursors and assembled to form immature particles. Those precursors are processed into functional components by proteinases. This type of assembly may be more accurate and economical than a system where particles are formed by assembling separate proteins with distinct pro作者: 貧窮地活 時(shí)間: 2025-3-30 09:28
HIV , Expression via a Ribosomal Frameshift,es is also strongly conserved (Figure 1) (Weiss ., 1982). The . and . genes are adjacent at the beginning of retroviral transcriptional unit and in most cases the 3′ end of . and the 5′ end of . overlap by up to a few hundred nucleotides with . in the ?1 translational phase with respect to .. Both g作者: 遍及 時(shí)間: 2025-3-30 14:57 作者: 領(lǐng)導(dǎo)權(quán) 時(shí)間: 2025-3-30 17:57
Biosynthesis and Processing of the , and , Polyproteins of Human Immunodeficiency Virus Type 1 in , encodes four group specific antigens, MA(p17), CA(p24), NC(p7) and p6, while the . gene codes for protease, reverse transcriptase/ribonuclease H (RT/RH, 66 kDa) and integrase (IN, 32 kDa) (Chassagne ..., 1986; Henderson ., 1988; Kramer ., 1986; Lightfoot ., 1986; Lillehoj ., 1988). The primary tran作者: 悠然 時(shí)間: 2025-3-30 20:46 作者: osteopath 時(shí)間: 2025-3-31 04:21
Three-dimensional Structure and Evolution of HIV-1 Protease, consequence the proteinase is an attractive target for prospective antiviral agents for the treatment of AIDS, and knowledge of its tertiary structure an important step in drug design. Following the observation (Toh . 1985) that retroviral proteinases shared a highly conserved sequence Asp-Thr/Ser-作者: 考古學(xué) 時(shí)間: 2025-3-31 06:10 作者: effrontery 時(shí)間: 2025-3-31 13:12
Expression of HIV-1 , and , Gene Products using Recombinant Baculoviruses,pression of heterologous gene products. Genes of interest are introduced into the genome of the . nuclear polyhedrosis virus (AcNPV) to give a helper independant recombinant virus that, upon infection of insect cells, produces the product encoded by the introduced gene in a regulated manner. Frequen作者: Legend 時(shí)間: 2025-3-31 16:32
Morphogenesis of Retroviruses: A Complex Role for the Matrix (MA) Protein in Assembly, Stability anne of an infected cell. They have common morphological features that reflect similar mechanisms of morphogenesis. The viral envelope is studded with glycoprotein knobbed-spikes, and in nascent particles surrounds an icosahedral capsid assembled mostly from internal structural proteins encoded by the作者: CRP743 時(shí)間: 2025-3-31 21:08 作者: CRP743 時(shí)間: 2025-3-31 23:56
Terminal Stages of Retrovirus Morphogenesis,ical and ultrastructural results of ours and other laboratories, over the past 15–20 years (Luftig and Kilham, 1971; Bolognesi, Luftig and Shaper, 1973; Yoshinaka and Luftig, 1977a,b; Jamjoom, Naso and Arlinghaus, 1976; Yoshinaka ., 1985; Katoh ., 1985; Traktman and Baltimore, 1982; Crawford and Gof
