標(biāo)題: Titlebook: Research in Computational Molecular Biology; 13th Annual Internat Serafim Batzoglou Conference proceedings 2009 Springer-Verlag Berlin Heid [打印本頁] 作者: detumescence 時間: 2025-3-21 17:38
書目名稱Research in Computational Molecular Biology影響因子(影響力)
書目名稱Research in Computational Molecular Biology影響因子(影響力)學(xué)科排名
書目名稱Research in Computational Molecular Biology網(wǎng)絡(luò)公開度
書目名稱Research in Computational Molecular Biology網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Research in Computational Molecular Biology被引頻次
書目名稱Research in Computational Molecular Biology被引頻次學(xué)科排名
書目名稱Research in Computational Molecular Biology年度引用
書目名稱Research in Computational Molecular Biology年度引用學(xué)科排名
書目名稱Research in Computational Molecular Biology讀者反饋
書目名稱Research in Computational Molecular Biology讀者反饋學(xué)科排名
作者: 磨碎 時間: 2025-3-21 21:54
Tetsuo Shibuya short- and long-term expression of foreign genes on neurons in the peripheral and central nervous systems. Examples will be given here for gene delivery to the adult rat nervous system using vectors which lack viral thymidine kinase activity and cannot replicate in neurons, focusing on the use of t作者: 粘土 時間: 2025-3-22 03:32 作者: cleaver 時間: 2025-3-22 06:57 作者: superfluous 時間: 2025-3-22 11:47
Cedric Chauve,Nadia El-Mabrouknant molecules to the brain, thymus, and hematopoietic system have appeared [reviewed in 2–5]. Ex-vivo gene therapy has also been used to treat a patient with familial hypercholesterolaemia. In this case, autologous hepatocytes were used to target expression of a recombinant LDL receptor, resulting 作者: Instinctive 時間: 2025-3-22 14:00
Feng Zhao,Jian Peng,Joe DeBartolo,Karl F. Freed,Tobin R. Sosnick,Jinbo Xuman restenotic lesions obtained using directional atherectomy demonstrated opposite conclusions. Pickering and colleagues [11] found peak cellular proliferation rates of about 20%, while in a similar study, O’Brien [12] reported a proliferation rate of less than 1%. Much debate has surfaced about th作者: 信條 時間: 2025-3-22 20:32
Sharon Bruckner,Falk Hüffner,Richard M. Karp,Ron Shamir,Roded Sharannant molecules to the brain, thymus, and hematopoietic system have appeared [reviewed in 2–5]. Ex-vivo gene therapy has also been used to treat a patient with familial hypercholesterolaemia. In this case, autologous hepatocytes were used to target expression of a recombinant LDL receptor, resulting 作者: interlude 時間: 2025-3-23 00:52
Rami Jaschek,Amos Tanayison. Having in mind to use . as a containment system for the release of recombinant DNA in the environment, this bacteria was also used as a recipient in a study to establish a model system assaying the intergeneric transmission and expression of cloned genes in soil samples (Top et al. 1990).作者: Resistance 時間: 2025-3-23 04:52
Nicholas D. Pattengale,Masoud Alipour,Olaf R. P. Bininda-Emonds,Bernard M. E. Moret,Alexandros Stamaterial to the recipient). However, recent reports have documented that transduction can be a fertile gene exchange system in natural ecosystems (Kokjohn 1989, Kokjohn and Miller 1992). We are using . as a model organism to study virus-mediated gene transfer in freshwater microbial populations (Morri作者: inflame 時間: 2025-3-23 08:35 作者: Offset 時間: 2025-3-23 11:05 作者: 舞蹈編排 時間: 2025-3-23 16:35 作者: 吸引人的花招 時間: 2025-3-23 21:05 作者: HERE 時間: 2025-3-23 22:10 作者: A簡潔的 時間: 2025-3-24 06:19
Xiang Zhang,Feng Pan,Yuying Xie,Fei Zou,Wei Wanggs or regulatory proteins, and in only a fraction of patients, and there is wide variation in individual response to these drugs or transcription factors. These studies highlight the importance for understanding the molecular mechanisms underlying hemoglobin switching so that future studies can be d作者: 沐浴 時間: 2025-3-24 08:41
Searching Protein 3-D Structures in Linear Time,se a series of preprocessing algorithms that enable faster queries. We checked the performance of our linear-expected-time algorithm through computational experiments over the whole PDB database. According to the experiments, our algorithm is 3.6 to 28 times faster than previously known algorithms f作者: 配偶 時間: 2025-3-24 14:11
Optimization-Based Peptide Mass Fingerprinting for Protein Mixture Identification,lation study, we identify a set of limiting factors that hinder the performance of PMF-based protein mixture identification. We argue that it is feasible to remove these limitations and PMF can be a powerful tool in the analysis of protein mixtures, especially in the identification of low-abundance 作者: hypnogram 時間: 2025-3-24 16:02 作者: Synapse 時間: 2025-3-24 21:01
New Perspectives on Gene Family Evolution: Losses in Reconciliation and a Link with Supertrees,the problem of computing a species tree that minimizes the number of gene duplications, given a set of gene trees, is in fact a slight variant of a supertree problem; (3) We show that deciding if a set of gene trees can be explained using only apparent duplications can be done efficiently, as well a作者: harpsichord 時間: 2025-3-24 23:55
Topology-Free Querying of Protein Interaction Networks,d approach, and with queries from less studied species, where only topology-free algorithms apply. . detects many more matches than QNet, while in both cases giving results that are highly functionally coherent.作者: LEVY 時間: 2025-3-25 03:46 作者: fulmination 時間: 2025-3-25 10:27 作者: Comedienne 時間: 2025-3-25 15:43 作者: Brittle 時間: 2025-3-25 17:49 作者: 臨時抱佛腳 時間: 2025-3-25 21:20
How Many Bootstrap Replicates Are Necessary?,computed at runtime to determine when enough replicates have been generated, and report on the first large-scale experimental study to assess the effect of the number of replicates on the quality of support values, including the performance of our proposed criteria. We run our tests on 17 diverse re作者: LINES 時間: 2025-3-26 01:55 作者: 玉米 時間: 2025-3-26 05:26 作者: 輕觸 時間: 2025-3-26 11:51
Combinatorial Algorithms for Structural Variation Detection in High Throughput Sequenced Genomes,y, the few existing algorithms for identifying structural variation among individuals using paired-end reads have not been designed to handle the short read lengths and the errors implied by these platforms. Here, we describe, for the first time, algorithms for identifying various forms of structura作者: HAVOC 時間: 2025-3-26 15:53 作者: novelty 時間: 2025-3-26 20:13 作者: prediabetes 時間: 2025-3-27 00:19
COE: A General Approach for Efficient Genome-Wide Two-Locus Epistasis Test in Disease Association S indexing structure, we can prune most of the SNP-pairs without compromising the optimality of the result. Our approach is especially efficient for large permutation test. Extensive experiments demonstrate that our approach provides orders of magnitude performance improvement over the brute force ap作者: mighty 時間: 2025-3-27 05:09 作者: insightful 時間: 2025-3-27 05:28
Bonnie Kirkpatrick,Javier Rosa,Eran Halperin,Richard M. Karp作者: Favorable 時間: 2025-3-27 12:57
Veli M?kinen,Gonzalo Navarro,Jouni Sirén,Niko V?lim?ki作者: 陰謀小團(tuán)體 時間: 2025-3-27 16:38 作者: 強(qiáng)制令 時間: 2025-3-27 21:13
Alexandre Donzé,Gilles Clermont,Axel Legay,Christopher J. Langmead作者: deface 時間: 2025-3-28 00:12 作者: Amorous 時間: 2025-3-28 03:56
Conference proceedings 2009as molecular sequence analysis, recognition of genes and regulatory elements, molecular evolution, protein structure, structural genomics, gene expression, gene networks, drug design, combinatorial libraries, computational proteomics, as well as structural and functional genomics.作者: Wallow 時間: 2025-3-28 09:22
Conference proceedings 2009, held in Tucson, Arisona, USA in May 2009. The 37 revised full papers presented were carefully reviewed and selected from 166 submissions. As the top conference in computational molecular biology, RECOMB addresses all current issues in algorithmic, theoretical, and experimental bioinformatics such 作者: Observe 時間: 2025-3-28 13:27 作者: filicide 時間: 2025-3-28 15:01 作者: 最高峰 時間: 2025-3-28 20:41
Parameter Synthesis in Nonlinear Dynamical Systems: Application to Systems Biology, scales to high-dimensional models and is exact if the given model is affine. We demonstrate our method on a model of the acute inflammatory response to bacterial infection, and identify initial conditions consistent with 3 biologically relevant outcomes.作者: oxidize 時間: 2025-3-29 01:10 作者: 小臼 時間: 2025-3-29 04:44
Optimization-Based Peptide Mass Fingerprinting for Protein Mixture Identification,ed on tandem Mass Spectrometry (MS/MS) data. The disadvantage is that MS/MS data only sequences a limited number of peptides and leaves many more peptides uncovered..Peptide Mass Fingerprinting (PMF) has been widely used to identify single purified proteins from single-stage MS data. Unfortunately, 作者: OWL 時間: 2025-3-29 09:44
Boosting Protein Threading Accuracy,ombining sequence and structure features to measure the quality of a sequence-template alignment so that a dynamic programming algorithm can be used to optimize the scoring function. However, a linear scoring function cannot fully exploit interdependency among features and thus, limits alignment acc作者: 細(xì)頸瓶 時間: 2025-3-29 13:05 作者: 延期 時間: 2025-3-29 15:48 作者: commensurate 時間: 2025-3-29 21:22 作者: appall 時間: 2025-3-30 02:31
Cross Species Expression Analysis of Innate Immune Response,n activate different sets of genes. Microarray studies of human and mouse cells infected with various pathogens identified hundreds of differentially expressed genes. However, combining these datasets to identify common and unique response patterns remained a challenge. We developed methods based on作者: 巨大沒有 時間: 2025-3-30 08:05 作者: 共棲 時間: 2025-3-30 08:14
Storage and Retrieval of Individual Genomes, length .. Examples of such collections are version control data and genome sequences of individuals, where the differences can be expressed by lists of basic edit operations. Flexible and efficient data analysis on a such typically huge collection is plausible using suffix trees. However, suffix tr作者: 難聽的聲音 時間: 2025-3-30 14:37 作者: 灌溉 時間: 2025-3-30 20:28
Parameter Synthesis in Nonlinear Dynamical Systems: Application to Systems Biology,r ODEs is that seemingly minor changes in initial conditions or parameters can lead to radically different behaviors. This is problematic because in general it is never possible to know/measure the precise state of any biological system due to measurement errors. The parameter synthesis problem is t作者: NOT 時間: 2025-3-30 23:40
Spatial Clustering of Multivariate Genomic and Epigenomic Information,ry and epigenetics marks on a global scale. This new experimental methodology was recently applied to map multiple histone marks and genomic factors, characterizing patterns of genome organization and discovering interactions among processes of epigenetic reprogramming during cellular differentiatio作者: 充滿裝飾 時間: 2025-3-31 03:56 作者: 蕁麻 時間: 2025-3-31 08:08
A Robust Bayesian Two-Sample Test for Detecting Intervals of Differential Gene Expression in Microa biology. A first and important step towards this goal is to detect genes whose expression levels are affected by altered external conditions. A range of methods to test for differential gene expression, both in static as well as in time-course experiments, have been proposed. While these tests answ作者: Infinitesimal 時間: 2025-3-31 11:37 作者: Malaise 時間: 2025-3-31 16:56
Combinatorial Algorithms for Structural Variation Detection in High Throughput Sequenced Genomes,These studies have typically been based high-cost library generation and Sanger sequencing; however, recent introduction of next-generation sequencing (NGS) technologies is changing how research in this area is conducted in a significant way. Highthroughput sequencing technologies such as 454, Illum作者: overture 時間: 2025-3-31 19:56
Optimizing PCR Assays for DNA Based Cancer Diagnostics,umor cells are frequently admixed with normal cells, particularly in early stage tumor samples, and thus the samples contain a high background of normal DNA. Detection is further confounded by the fact that the rearrangement boundaries are not conserved across individuals, and might vary over hundre作者: PANEL 時間: 2025-4-1 00:47
The Multi-State Perfect Phylogeny Problem with Missing and Removable Data: Solutions via Integer-Prs that extend the utility of the multi-state perfect phylogeny model: . where some entries in the input are missing and the question is whether (bounded) values for the missing data can be imputed so that the resulting data has a multi-state perfect phylogeny; . where we want to minimize the number 作者: alcoholism 時間: 2025-4-1 02:27 作者: 山崩 時間: 2025-4-1 09:40 作者: 不確定 時間: 2025-4-1 12:01 作者: Eulogy 時間: 2025-4-1 15:42 作者: 嬉耍 時間: 2025-4-1 21:54 作者: CURT 時間: 2025-4-1 23:05 作者: 傷心 時間: 2025-4-2 05:14
