標(biāo)題: Titlebook: Research in Computational Molecular Biology; 17th Annual Internat Minghua Deng,Rui Jiang,Xuegong Zhang Conference proceedings 2013 Springer [打印本頁] 作者: cessation 時(shí)間: 2025-3-21 20:09
書目名稱Research in Computational Molecular Biology影響因子(影響力)
書目名稱Research in Computational Molecular Biology影響因子(影響力)學(xué)科排名
書目名稱Research in Computational Molecular Biology網(wǎng)絡(luò)公開度
書目名稱Research in Computational Molecular Biology網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Research in Computational Molecular Biology被引頻次
書目名稱Research in Computational Molecular Biology被引頻次學(xué)科排名
書目名稱Research in Computational Molecular Biology年度引用
書目名稱Research in Computational Molecular Biology年度引用學(xué)科排名
書目名稱Research in Computational Molecular Biology讀者反饋
書目名稱Research in Computational Molecular Biology讀者反饋學(xué)科排名
作者: FLEET 時(shí)間: 2025-3-21 22:07
Research in Computational Molecular Biology978-3-642-37195-0Series ISSN 0302-9743 Series E-ISSN 1611-3349 作者: 有偏見 時(shí)間: 2025-3-22 01:55
Lecture Notes in Computer Sciencehttp://image.papertrans.cn/r/image/827958.jpg作者: RECUR 時(shí)間: 2025-3-22 05:06 作者: CRANK 時(shí)間: 2025-3-22 11:07
An Optimal Algorithm for Building the Majority Rule Consensus Tree,abels is presented. Its worst-case running time is .(..), where .?is the size of the leaf label set and .?is the number of input phylogenetic trees. This is optimal since the input size is Ω(..). Experimental results show that the algorithm is fast in practice.作者: heckle 時(shí)間: 2025-3-22 15:58
Minghua Deng,Rui Jiang,Xuegong ZhangUp to date results.Fast track conference proceedings.State of the art research作者: gonioscopy 時(shí)間: 2025-3-22 19:43
Conference proceedings 2013, held in Beijing, China, in April 2013. The 32 revised full papers were carefully reviewed and selected from 167 submissions. The papers cover a wide range of topics including molecular sequence analysis; genes and regulatory elements; molecular evolution; gene expression; biological networks; sequ作者: 愛了嗎 時(shí)間: 2025-3-22 22:10 作者: CAB 時(shí)間: 2025-3-23 04:47 作者: LOPE 時(shí)間: 2025-3-23 08:02
SEME: A Fast Mapper of Illumina Sequencing Reads with Statistical Evaluation,the sequencing reads of the Illumina platform get longer and their quality scores get higher. According to our calculation, this allows perfect .-mer seed match for almost all reads when a close reference genome is available subject to reasonable specificity. Our another observation is that the majo作者: CANT 時(shí)間: 2025-3-23 13:22 作者: 可卡 時(shí)間: 2025-3-23 16:32 作者: 送秋波 時(shí)間: 2025-3-23 19:24
Analysis of Metabolic Evolution in Bacteria Using Whole-Genome Metabolic Models, complements) for multiple bacterial species. These reaction complements can be considered as trait representations and can be used for ancestral state reconstruction, to infer the most likely metabolic complements of common ancestors of all bacteria with generated metabolic models. We present here 作者: 推遲 時(shí)間: 2025-3-23 23:21 作者: Arthr- 時(shí)間: 2025-3-24 04:24
IPED: Inheritance Path Based Pedigree Reconstruction Algorithm Using Genotype Data, have been proposed to automate the process of pedigree reconstruction given the genotypes or haplotypes of a set of individuals. Current methods, unfortunately, are very time consuming and inaccurate for complicated pedigrees such as pedigrees with inbreeding. In this work, we propose an efficient 作者: custody 時(shí)間: 2025-3-24 07:53 作者: 愚笨 時(shí)間: 2025-3-24 11:38 作者: incontinence 時(shí)間: 2025-3-24 18:24 作者: figment 時(shí)間: 2025-3-24 19:03 作者: 拘留 時(shí)間: 2025-3-25 02:05 作者: paltry 時(shí)間: 2025-3-25 03:45
Assembling Genomes and Mini-metagenomes from Highly Chimeric Reads,bacteria. However, single-cell assembly projects are challenging due to (i) the highly non-uniform read coverage, and (ii) a greatly elevated number of chimeric reads and read pairs. While recently developed single-cell assemblers have addressed the former challenge, methods for assembling highly ch作者: Essential 時(shí)間: 2025-3-25 07:38
Inferring Intra-tumor Heterogeneity from High-Throughput DNA Sequencing Data,ncerous cells in a tumor are descended from a single founder cell and that descendants of this cell acquired multiple mutations beneficial for tumor growth through rounds of selection and . expansion. A tumor is thus a heterogeneous population of cells, with different subpopulations of cells contain作者: incisive 時(shí)間: 2025-3-25 12:43
NP-MuScL: Unsupervised Global Prediction of Interaction Networks from Multiple Data Sources,urce. However, in many real world applications, multiple data sources, such as microarray and ISH measurements of mRNA abundances, are available to offer multi-view information about the same set of genes. We propose NP-MuScL (nonparanormal multi-source learning) to estimate a gene interaction netwo作者: Ingrained 時(shí)間: 2025-3-25 17:21 作者: 效果 時(shí)間: 2025-3-25 21:50 作者: Diuretic 時(shí)間: 2025-3-26 00:18
An Accurate Method for Inferring Relatedness in Large Datasets of Unphased Genotypes via an Embedde For example, in genome-wide association studies, the cohort members are assumed to be unrelated to one another. Investigators can correct for individuals in a cohort with previously-unknown shared familial descent by detecting genomic segments that are shared between them, which are considered to b作者: 躲債 時(shí)間: 2025-3-26 07:42 作者: MARS 時(shí)間: 2025-3-26 10:54 作者: 小官 時(shí)間: 2025-3-26 12:48
Reconciliation Revisited: Handling Multiple Optima When Reconciling with Duplication, Transfer, andfficiently sample the space of optimal reconciliations uniformly at random in .(..) time, where . and . denote the number of genes and species, respectively. We use these samples to understand how different optimal reconciliations vary in their node mapping and event assignments, and to investigate the impact of varying event costs.作者: 存心 時(shí)間: 2025-3-26 17:18
Dissecting Cancer Heterogeneity with a Probabilistic Genotype-Phenotype Model, of the subtypes that best explain the patient similarity network. Our approach does not assume predefined subtypes nor does it assume that such subtypes have to be uniquely defined. That is, we do not assume that there exist “the” disease subtype model but rather we consider a distribution of such models providing a probabilistic context.作者: Admonish 時(shí)間: 2025-3-27 00:49
Identification of Ultramodified Proteins Using Top-Down Spectra,fy complex PTM patterns. We propose a new algorithm, MS-Align-E, that identifies both expected and unexpected PTMs in ultramodified proteins. We demonstrate that MS-Align-E identifies many protein forms of histone H4 and benchmark it against the currently accepted software tools.作者: 共棲 時(shí)間: 2025-3-27 03:39
Distinguishing between Genomic Regions Bound by Paralogous Transcription Factors,yc versus Mad2, using features that reflect the DNA binding specificities of putative co-factors. When applied to c-Myc/Mad2 DNA binding data, our algorithm can distinguish between genomic regions bound uniquely by c-Myc versus Mad2 with 87% accuracy.作者: Concomitant 時(shí)間: 2025-3-27 07:55 作者: Scleroderma 時(shí)間: 2025-3-27 10:27 作者: 戲法 時(shí)間: 2025-3-27 16:15
A Linear Inside-Outside Algorithm for Correcting Sequencing Errors in Structured RNAs,ce alignment with a consensus structure. We develop a scoring scheme combining classical stacking base pair energies to novel isostericity scales, and apply our techniques to correct point-wise errors in 5s rRNA sequences. Our results suggest that . is a promising algorithm to complement existing tools in the NGS error-correction pipeline.作者: 重畫只能放棄 時(shí)間: 2025-3-27 21:08 作者: outer-ear 時(shí)間: 2025-3-28 01:09 作者: 賠償 時(shí)間: 2025-3-28 05:15 作者: Noctambulant 時(shí)間: 2025-3-28 10:17
Shijian Chen,Anqi Wang,Lei M. Li in the. gene and in the regulation of genes of the retinoblastoma pathway such as . or cyclin .1 occur in a large percentage of tumors and have been well studied. Reintroduction or overexpression of genes suppressing proliferation or promoting apoptosis offers a potential for selective suicide of t作者: 把手 時(shí)間: 2025-3-28 14:27
Dong-Yeon Cho,Teresa M. Przytyckas human diseases, scientists have been fas- nated with the possibility of treating certain diseases by transducing foreign DNA into the affected cells. Initially, it was proposed that the foreign DNA could either replace defective nonfunctional genes, or code for therapeutic proteins. This concept h作者: Tartar 時(shí)間: 2025-3-28 16:04
Itamar Eskin,Farhad Hormozdiari,Lucia Conde,Jacques Riby,Chris Skibola,Eleazar Eskin,Eran Halperinresponses. This strategy, now known as genetic or DNA immunization, was first described by Johnston et al. in 1992. They reported that bombardment of murine skin with an expression plasmid encoding human growth hormone coated onto microscopic gold particles using a gene gun resulted not only in the 作者: 偏離 時(shí)間: 2025-3-28 21:08
Ali A. Faruqi,William A. Bryant,John W. Pinneythese approaches using an IGF-I antisense RNA strategy of treatment. Insulin-like growth factor I (IGF-I) and IGF-II have pivotal roles in cell proliferation and development (for review see 1–4). The preponderance of peptide synthesis and activity occur during fetal development. Protein synthesis is作者: dry-eye 時(shí)間: 2025-3-29 01:25 作者: Gullible 時(shí)間: 2025-3-29 05:16 作者: Harpoon 時(shí)間: 2025-3-29 07:17
Jesper Jansson,Chuanqi Shen,Wing-Kin Sung(herceptin) for breast cancer or Iressa (gefitinib) for non-small cell lung cancer among others are limited by lack of efficacy, cellular resistance, and toxicity. Dose escalation and combination therapies designed to overcome resistance and increase efficacy are limited by a narrow therapeutic inde作者: Expurgate 時(shí)間: 2025-3-29 13:57
Kyowon Jeong,Sangtae Kim,Pavel A. Pevzneris book chapter we describe the selection and characterization of DNA aptamers specific to the human epidermal growth factor receptor 2 (ERBB2/HER2), an oncogenic tyrosine kinase. First, a DNA aptamer library is applied and ERBB2-specific aptamers are selected using SELEX. Binders are subcloned into作者: 使成波狀 時(shí)間: 2025-3-29 18:48 作者: 命令變成大炮 時(shí)間: 2025-3-29 23:22
Xiaowen Liu,Shawna Hengel,Si Wu,Nikola Toli?,Ljiljana Pasa-Toli?,Pavel A. Pevzner is raising new prospects on the outcome of an effective anticancer treatment. It is well known that the success of gene transfer to cells and subsequent expression is strictly affected by the vector manufacturing process. Therefore, several downstream methods have been proposed to achieve high quan作者: Microgram 時(shí)間: 2025-3-30 00:23
Alina Munteanu,Raluca Gordanion relationships. Though success with DNA transfer was reported as early as 1962 (Szybalska and Szybalski, 1962), widespread use of this method had to await later developments. On the basis of a method developed by Graham and van der Eb (1973), Wigler .. (1977) and Maitland and McDougall (1977) suc作者: 無孔 時(shí)間: 2025-3-30 07:05
Sergey Nurk,Anton Bankevich,Dmitry Antipov,Alexey Gurevich,Anton Korobeynikov,Alla Lapidus,Andrey Prduring their sexual reproductive phase, cell-to-cell transfer of single-stranded DNA has been demonstrated (Lederberg, 1947; Wollman .., 1956). In addition, DNA isolated from one genotype could stably change the phenotype of another bacterium (Avery .., 1944). Similarly, the infection of bacteria by作者: 怪物 時(shí)間: 2025-3-30 11:31
Roy Ronen,Nitin Udpa,Eran Halperin,Vineet Bafnaby the fusion of the appropriate DNA regulatory sequences to reporter genes have led to the identification of a great number of DNA control elements that constitute eukaryotic promoters. Recently, transcription factors that interact with specific DNA control elements have been purified and the cDNAs作者: sultry 時(shí)間: 2025-3-30 15:18 作者: Ascendancy 時(shí)間: 2025-3-30 20:26
Dong-Yeon Cho,Teresa M. Przytycka to tumors, the direct killing of tumor cells, and direct int- ference with tumor growth. In this context, gene transfer systems, tumor-specific expression vectors, and novel therapeutic genes 978-0-89603-843-1978-1-59259-086-5Series ISSN 1543-1894 Series E-ISSN 1940-6037 作者: 討好美人 時(shí)間: 2025-3-30 22:00
SEME: A Fast Mapper of Illumina Sequencing Reads with Statistical Evaluation, two parts corresponding to the seed and extension step, and the composite result provides an approximate overall reliability estimate of each mapping. We compare SEME with some existing mapping methods on several data sets, and SEME shows better performance in terms of both running time and mapping作者: abracadabra 時(shí)間: 2025-3-31 02:37
eALPS: Estimating Abundance Levels in Pooled Sequencing Using Available Genotyping Data,purious associations. Fortunately, it is often the case that the genotype data of at least some of the individuals in the pool is known. Here, we propose a method (eALPS) that uses the genotype data in conjunction with the pooled sequence data in order to accurately estimate the proportions of the s作者: Lipoma 時(shí)間: 2025-3-31 06:59
Analysis of Metabolic Evolution in Bacteria Using Whole-Genome Metabolic Models,o its current habitat in the human colon is also analysed. Our analysis shows that the capability to utilize N-Acetyl-neuraminic acid as a carbon source has been gained, rather than having been present in the . ancestor, as has the capability to synthesise phthiocerol dimycocerosate which could pote作者: 抱狗不敢前 時(shí)間: 2025-3-31 10:31
Detecting Protein Conformational Changes in Interactions via Scaling Known Structures,er methods for the same purpose. On 20 complexes, we obtained an average iRMSD of 1.55?, which compares favorably with the average iRMSD of 1.94??in the predictions from FiberDock. Compared with ZDOCK, our results are of 0.35??less in average iRMSD on the medium difficulty group, and 0.81??less on t作者: 收養(yǎng) 時(shí)間: 2025-3-31 15:10 作者: 談判 時(shí)間: 2025-3-31 19:34
UniNovo : A Universal Tool for , Peptide Sequencing,vo is superior to other tools for ETD spectra and superior or comparable to others for CID and HCD spectra. UniNovo also estimates the probability that each reported reconstruction is correct, using simple statistics that are readily obtained from a small training dataset. We demonstrate that the es作者: COKE 時(shí)間: 2025-4-1 01:32
Efficiently Identifying Significant Associations in Genome-Wide Association Studies, informative SNPs, or proxies, across the genome are tested. Based on their observed associations, our approach locates the regions which may contain significant SNPs and only tests additional SNPs from those regions. We show through simulations and analysis of real GWAS datasets that the proposed t作者: 樣式 時(shí)間: 2025-4-1 02:00 作者: Ordeal 時(shí)間: 2025-4-1 07:47
NP-MuScL: Unsupervised Global Prediction of Interaction Networks from Multiple Data Sources,sent an efficient algorithm to estimate such a model in the high dimensional scenario. Results are reported on synthetic data, where NP-MuScL outperforms baseline algorithms significantly, even in the presence of noisy data sources. Experiments are also run on two real-world scenarios: two yeast mic作者: 使迷醉 時(shí)間: 2025-4-1 10:17
An Accurate Method for Inferring Relatedness in Large Datasets of Unphased Genotypes via an Embeddeaccurate method to detect IBD segments is required..We present PARENTE, a novel method for detecting related pairs of individuals and shared haplotypic segments within these pairs. PARENTE is a computationally-efficient method based on an embedded likelihood ratio test. As demonstrated by the result作者: sultry 時(shí)間: 2025-4-1 18:15 作者: 騷擾 時(shí)間: 2025-4-1 21:51
