標(biāo)題: Titlebook: Research in Computational Molecular Biology; 23rd Annual Internat Lenore J. Cowen Conference proceedings 2019 Springer Nature Switzerland A [打印本頁] 作者: damped 時(shí)間: 2025-3-21 17:54
書目名稱Research in Computational Molecular Biology影響因子(影響力)
書目名稱Research in Computational Molecular Biology影響因子(影響力)學(xué)科排名
書目名稱Research in Computational Molecular Biology網(wǎng)絡(luò)公開度
書目名稱Research in Computational Molecular Biology網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Research in Computational Molecular Biology被引頻次
書目名稱Research in Computational Molecular Biology被引頻次學(xué)科排名
書目名稱Research in Computational Molecular Biology年度引用
書目名稱Research in Computational Molecular Biology年度引用學(xué)科排名
書目名稱Research in Computational Molecular Biology讀者反饋
書目名稱Research in Computational Molecular Biology讀者反饋學(xué)科排名
作者: Oration 時(shí)間: 2025-3-21 21:06
https://doi.org/10.1007/978-3-030-17083-7algorithms; artificial intelligence; biological networks; data mining; genetics and association studies; 作者: 占卜者 時(shí)間: 2025-3-22 01:33
Conference proceedings 2019, DC, USA, in April 2019...The 17?extended and 20 short abstracts?presented were carefully reviewed?and selected from 175 submissions. The short abstracts are included in?the back matter of the volume. The papers report on original research in all?areas of computational molecular biology and bioinformatics..作者: headlong 時(shí)間: 2025-3-22 07:55
978-3-030-17082-0Springer Nature Switzerland AG 2019作者: 費(fèi)解 時(shí)間: 2025-3-22 10:15
Research in Computational Molecular Biology978-3-030-17083-7Series ISSN 0302-9743 Series E-ISSN 1611-3349 作者: nullify 時(shí)間: 2025-3-22 15:33 作者: perimenopause 時(shí)間: 2025-3-22 20:55 作者: 團(tuán)結(jié) 時(shí)間: 2025-3-23 01:09
Clustering of Long-Read Transcriptome Data Using a Greedy, Quality-Value Based Algorithm,es, and read depths. Our results demonstrate that isONclust is a substantial improvement over previous approaches, both in terms of overall accuracy and/or scalability to large datasets. Our tool is available at ..作者: elucidate 時(shí)間: 2025-3-23 01:34
A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer,dent-mutation models or strand oblivous models, achieving substantially higher likelihood on held-out data. We apply this model to characterize the processivity of mutagenic processes across multiple types of cancer in terms of replication and transcriptional strand-coordination.作者: exigent 時(shí)間: 2025-3-23 07:28
An Efficient, Scalable and Exact Representation of High-Dimensional Color Information Enabled via dation-level variation detection in metagenomic samples, large scale sequence search, and cdbg-based reference sequence indices. As samples or genomes are added to the cdbg, the color information comes to dominate the space required to represent this data structure..In this paper, we show how to repr作者: 誘騙 時(shí)間: 2025-3-23 13:28
Identifying Clinical Terms in Free-Text Notes Using Ontology-Guided Machine Learning,has a large impact on electronic health record analysis. The mining of such terms is complicated by the broad use of synonyms and non-standard terms in medical documents. Here we presented a machine learning model for concept recognition in large unstructured text which optimizes the use of ontologi作者: 不利 時(shí)間: 2025-3-23 15:36 作者: Polydipsia 時(shí)間: 2025-3-23 21:45 作者: 最高峰 時(shí)間: 2025-3-24 01:44
: Differentially Methylated Region Detection with Change Point Models,that are differentially methylated (DMRs) between different conditions. Many methods have been developed, which focus primarily on the setting of two-group comparison. We develop a DMR detecting method . for WGBS data, which is applicable for a wide range of experimental designs beyond the two-group作者: Nomadic 時(shí)間: 2025-3-24 06:13
On the Complexity of Sequence to Graph Alignment,ntations. Aligning sequences to graphs is a fundamental operation on several types of sequence graphs (variation graphs, assembly graphs, pan-genomes, etc.) and their biological applications. Though research on sequence to graph alignments is nascent, it can draw from related work on pattern matchin作者: judiciousness 時(shí)間: 2025-3-24 10:32
Minimization-Aware Recursive , (,): A Novel, Provable Algorithm that Accelerates Ensemble-Based Pro. The previous state of the art, iMinDEE-.-., computes provable .-approximations to partition functions of protein states (e.g., bound vs. unbound) by computing provable, admissible pairwise-minimized energy lower bounds on protein conformations and using the . enumeration algorithm to return a gap-作者: 描述 時(shí)間: 2025-3-24 13:32
Sparse Binary Relation Representations for Genome Graph Annotation,mand. In recent research, several graph data structures have been proposed to represent large sets of sequencing data and to allow for efficient querying of sequences. In particular, the concept of labeled de Bruijn graphs has been explored by several groups. While there has been good progress towar作者: 飛來飛去真休 時(shí)間: 2025-3-24 17:10 作者: 思想上升 時(shí)間: 2025-3-24 20:28
Efficient Construction of a Complete Index for Pan-Genomics Read Alignment,ng databases containing thousands of genomes. To understand why, it helps to examine the main components of the FM-index in more detail, which is a rank data structure over the Burrows-Wheeler Transform (.) of the string that will allow us to find the interval in the string’s suffix array (.) contai作者: 思鄉(xiāng)病 時(shí)間: 2025-3-25 01:06 作者: 耕種 時(shí)間: 2025-3-25 05:15 作者: Motilin 時(shí)間: 2025-3-25 10:21
Fast Approximation of Frequent ,-mers and Applications to Metagenomics, analysis. While several methods have been designed for the exact or approximate solution of this problem, they all require to process the entire dataset, that can be extremely expensive for high-throughput sequencing datasets. While in some applications it is crucial to estimate all .-mers and thei作者: Nutrient 時(shí)間: 2025-3-25 15:02 作者: 船員 時(shí)間: 2025-3-25 19:10
A Sticky Multinomial Mixture Model of Strand-Coordinated Mutational Processes in Cancer,given cancer genome are independent of one another. Recently, it was discovered that certain segments of mutations, termed processive groups, occur on the same DNA strand and are generated by a single process or signature. Here we provide a first probabilistic model of mutational signatures that acc作者: 等級(jí)的上升 時(shí)間: 2025-3-25 23:57
Disentangled Representations of Cellular Identity,ic basis vectors that are then decoded into gene expression levels. The basis vectors are learned with a deep autoencoder model from single-cell RNA-seq data. Linear arithmetic in the disentangled representation successfully predicts nonlinear gene expression interactions between biological pathways作者: attenuate 時(shí)間: 2025-3-26 02:30
RENET: A Deep Learning Approach for Extracting Gene-Disease Associations from Literature,ct knowledge from these articles to support research and genetic testing. In particular, the extraction of gene-disease associations is mostly studied. However, existing text-mining tools for extracting gene-disease associations have limited capacity, as each sentence is considered separately. Our e作者: gene-therapy 時(shí)間: 2025-3-26 07:46 作者: 微塵 時(shí)間: 2025-3-26 08:51 作者: fabricate 時(shí)間: 2025-3-26 15:11 作者: antedate 時(shí)間: 2025-3-26 18:33
0302-9743 hort abstracts are included in?the back matter of the volume. The papers report on original research in all?areas of computational molecular biology and bioinformatics..978-3-030-17082-0978-3-030-17083-7Series ISSN 0302-9743 Series E-ISSN 1611-3349 作者: GROSS 時(shí)間: 2025-3-26 22:15
ents in novel receptor/liposome-based transfection systems have made nonviral gene therapy a real possibility. Described here is a novel, high-efficiency, nonviral protocol for delivery of genes into permeabilized primary cultured cells forming a first step toward ex vivo gene therapy for the repair作者: 神圣將軍 時(shí)間: 2025-3-27 01:28
Fatemeh Almodaresi,Prashant Pandey,Michael Ferdman,Rob Johnson,Rob Patro Injury to the alveolar-capillary barrier and lung inflammation lead to intrapulmonary shunting of blood, surfactant depletion, and pulmonary vascular obstruction. Although the exact incidence of ARDS is unknown, there is little doubt that tens of thousands of patients develop this syndrome annually作者: 變量 時(shí)間: 2025-3-27 09:16
Aryan Arbabi,David R. Adams,Sanja Fidler,Michael Brudnoyriad of endovascular or inhaled toxins, a series of temporally and spatially overlapping injury and repair events all too often result in a dysfunctional fibrotic lung. The fibroproliferative phase of acute lung injury is characterized by progressive accumulation of interstitial and alveolar myofib作者: Kernel 時(shí)間: 2025-3-27 11:31 作者: 小樣他閑聊 時(shí)間: 2025-3-27 17:24 作者: Anthology 時(shí)間: 2025-3-27 19:40 作者: LIEN 時(shí)間: 2025-3-28 01:12
Chirag Jain,Haowen Zhang,Yu Gao,Srinivas Aluru the target cancer cells and high transduction of nontarget normal organs. To address these issues, we have been working on “retargeting” of Ad vectors via transductional or transcriptional targeting. Transductional targeting has been achieved with application of various bridging moieties, genetical作者: 埋葬 時(shí)間: 2025-3-28 03:30 作者: Harness 時(shí)間: 2025-3-28 06:32
Mikhail Karasikov,Harun Mustafa,Amir Joudaki,Sara Javadzadeh-No,Gunnar R?tsch,André Kahlesled to identify a suitable virus, which though unable to cause disease, retained the capability to replicate in cancer cells. In principal, the productive growth of the virus would kill or lyse malignant cells and the newly minted viral progeny would spread the infection, resulting ultimately in the作者: 極端的正確性 時(shí)間: 2025-3-28 12:27 作者: Freeze 時(shí)間: 2025-3-28 17:47 作者: 受人支配 時(shí)間: 2025-3-28 22:43
Haoyun Lei,Bochuan Lyu,E. Michael Gertz,Alejandro A. Sch?ffer,Xulian Shi,Kui Wu,Guibo Li,Liqin Xu,Yole functional cure for HIV.Comprises a thorough and methodic.This Brief describes the concept and realization of gene therapy for HIV from the unique historic perspective and insight of two pioneers of the clinical applications of stem cell gene therapy for HIV..Gerhard Bauer applied ribozyme-anti-H作者: CLOWN 時(shí)間: 2025-3-29 00:00 作者: 錢財(cái) 時(shí)間: 2025-3-29 06:53 作者: 大漩渦 時(shí)間: 2025-3-29 09:12 作者: 過時(shí) 時(shí)間: 2025-3-29 15:25 作者: Aprope 時(shí)間: 2025-3-29 16:28 作者: deciduous 時(shí)間: 2025-3-29 21:01
Ye Wu,Ruibang Luo,Henry C. M. Leung,Hing-Fung Ting,Tak-Wah Lamsing gene and mutated gene or downregulate a causal gene. Despite the versatility of gene therapy, one of the main limitations lies in the irreversibility of the process: once delivered to target cells, the gene of interest is constitutively expressed and cannot be removed. Therefore, efficient, saf作者: 盡忠 時(shí)間: 2025-3-30 02:07
ers in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; Wh作者: decode 時(shí)間: 2025-3-30 06:56 作者: Gene408 時(shí)間: 2025-3-30 09:12
Younhun Kim,Frederic Koehler,Ankur Moitra,Elchanan Mossel,Govind RamnarayanMBE) and a member of the Tissue Engineering International & Regenerative Medicine Society (TERMIS)-Asia Pacific Council.978-3-642-53922-0978-3-642-53923-7Series ISSN 2193-097X Series E-ISSN 2193-0988 作者: 無能力 時(shí)間: 2025-3-30 13:16 作者: 新鮮 時(shí)間: 2025-3-30 18:33 作者: backdrop 時(shí)間: 2025-3-30 22:26
An Efficient, Scalable and Exact Representation of High-Dimensional Color Information Enabled via ddbg itself can be used as an efficient mechanism to search for approximate nearest neighbors in this space. While our approach reduces the encoding size of the color information even for relatively small cdbgs (hundreds of experiments), the gains are particularly consequential as the number of poten作者: 跳脫衣舞的人 時(shí)間: 2025-3-31 04:43
Identifying Clinical Terms in Free-Text Notes Using Ontology-Guided Machine Learning,izes the biomedical ontology structure to optimize the embedding of various terms and has fewer training constraints than previous methods. We train our model on two biomedical ontologies, the Human Phenotype Ontology (HPO) and SNOMED-CT.. We tested our model trained on HPO on two different data set作者: 劇毒 時(shí)間: 2025-3-31 05:50
Learning Robust Multi-label Sample Specific Distances for Identifying HIV-1 Drug Resistance,on. In this paper, we propose a novel multi-label Robust Sample Specific Distance (RSSD) method to identify multi-class HIV drug resistance. Our method is novel in that it can illustrate the relative strength of the drug resistance of a reverse transcriptase sequence against a given drug nucleoside 作者: 宇宙你 時(shí)間: 2025-3-31 09:45 作者: jarring 時(shí)間: 2025-3-31 15:22
On the Complexity of Sequence to Graph Alignment,edit distance models for alphabets of size .. For the case where only changes to the sequence are permitted, we present an . time algorithm, where . denotes the query size, and . and . denote the vertex and edge sets of the graph, respectively. Our result is generalizable to both linear and affine g作者: Occupation 時(shí)間: 2025-3-31 17:33
