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標(biāo)題: Titlebook: Regulation of the Contractile Cycle in Smooth Muscle; Takeshi Nakano (Professor),David J. Hartshorne (Pr Conference proceedings 1995 Sprin [打印本頁]

作者: crusade    時(shí)間: 2025-3-21 18:42
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作者: Pert敏捷    時(shí)間: 2025-3-21 22:10
Kenji Kitamura,Hirosi Kuriyamaners, and medical examiners.Includes general topics not typi.Forensic Pathology for Police, Death Investigators, Attorneys, and Forensic Scientists is a forensic pathology book specifically written for professionals who interact with forensic pathologists. The book includes sections that address var
作者: Terrace    時(shí)間: 2025-3-22 02:51
Hideaki Karakit chest and abdominal injuries, followed by falls. While mostly seen following accidents, blunt abdominal injuries are, after head injury, the most common cause of homicide in the younger child..Isolated thoracic or abdominal injuries are less common than combined injuries in both anatomical areas.
作者: inclusive    時(shí)間: 2025-3-22 08:30
Hideo KanaideKnowledge of the cause of death contributes to the determination of the manner of death by medical examiners and coroners, who are occasionally assisted by law enforcement officers. In the process of establishing the cause and manner of death, representatives of various investigative bodies have sev
作者: 裂口    時(shí)間: 2025-3-22 09:49

作者: 冒失    時(shí)間: 2025-3-22 15:05
Takeo Itoh,Yoshimasa Watanabe,Makoto Yoshida,Akito Suzukincludes supplementary material: The human foot is a complex body part composed of fifty-two bones, which is twenty-five percent of all the bones in the body. Nonetheless, the foot is often viewed by the public and doctors as a “minor” body part. Similarly, the importance of pedal evidence in crime i
作者: OREX    時(shí)間: 2025-3-22 19:53

作者: 專橫    時(shí)間: 2025-3-22 22:22

作者: Galactogogue    時(shí)間: 2025-3-23 02:45
Satoshi Matsushima,Masaaki Ito,David J. Hartshorne,Vince Guerriero Jr. often viewed by the public and doctors as a “minor” body part. Similarly, the importance of pedal evidence in crime investigation has also long been undervalued, but as footwear evidence has become more commonly used in forensic situations, so has pedal evidence, which is why this seminal work is s
作者: Fulminate    時(shí)間: 2025-3-23 06:45
Kristine E. Kamm,Katherine Luby-Phelps,Malu G. Tansey,Patricia J. Gallagher,James T. Stull often viewed by the public and doctors as a “minor” body part. Similarly, the importance of pedal evidence in crime investigation has also long been undervalued, but as footwear evidence has become more commonly used in forensic situations, so has pedal evidence, which is why this seminal work is s
作者: 閹割    時(shí)間: 2025-3-23 10:48
Li-Hong Ye,Kohichi Hayakawa,Tsuyoshi Okagaki,Kazuhiro Kohama often viewed by the public and doctors as a “minor” body part. Similarly, the importance of pedal evidence in crime investigation has also long been undervalued, but as footwear evidence has become more commonly used in forensic situations, so has pedal evidence, which is why this seminal work is s
作者: 樣式    時(shí)間: 2025-3-23 15:12
A. P. Somlyo,M. Gong,K. Iizuka,T. Haystead,A. V. Somlyo often viewed by the public and doctors as a “minor” body part. Similarly, the importance of pedal evidence in crime investigation has also long been undervalued, but as footwear evidence has become more commonly used in forensic situations, so has pedal evidence, which is why this seminal work is s
作者: inspired    時(shí)間: 2025-3-23 21:30
Masaaki Ito,Hiroyuki Shimizu,Masatoshi Miyahara,Jian-Hua Feng,Setsuya Okubo,Kazuhito Ichikawa,Tokuji often viewed by the public and doctors as a “minor” body part. Similarly, the importance of pedal evidence in crime investigation has also long been undervalued, but as footwear evidence has become more commonly used in forensic situations, so has pedal evidence, which is why this seminal work is s
作者: QUAIL    時(shí)間: 2025-3-23 22:45

作者: heckle    時(shí)間: 2025-3-24 02:27
Toshio Tanaka,Michiko Naka,Terumasa Mino,Uhito Yuasa,Fumiaki Nakamura,Junichi Yamamoto,Satoshi Matsu often viewed by the public and doctors as a “minor” body part. Similarly, the importance of pedal evidence in crime investigation has also long been undervalued, but as footwear evidence has become more commonly used in forensic situations, so has pedal evidence, which is why this seminal work is s
作者: 頂點(diǎn)    時(shí)間: 2025-3-24 08:19

作者: 驕傲    時(shí)間: 2025-3-24 11:25

作者: QUAIL    時(shí)間: 2025-3-24 17:47

作者: Mirage    時(shí)間: 2025-3-24 21:35

作者: 空中    時(shí)間: 2025-3-25 01:09

作者: 有偏見    時(shí)間: 2025-3-25 06:30

作者: inspired    時(shí)間: 2025-3-25 08:59
Cytosolic Calcium Concentration-Force Relation in Vascular Smooth Muscle,e relation during contraction and relaxation. During both high external K.- and stable thromboxane A. analog (U-46619)-induced contractions the actively developed force was much greater at a high resting load, although the [Ca.]. transients were not affected by changes in the resting load. The basic
作者: 流浪    時(shí)間: 2025-3-25 13:15

作者: promote    時(shí)間: 2025-3-25 17:46

作者: 性行為放縱者    時(shí)間: 2025-3-25 23:31
Regulation of Ca2+-Dependent Phosphorylation of 20-kDa Myosin Light Chain by the Small Molecular Weion of 20-kDa myosin light chain (MLC.) in skinned smooth muscle preparations. In β-escin-permeabilized cultured aortic smooth muscle cells, GTPγS enhances Ca.-induced phosphorylation of MLC. in a concentration-dependent manner, which is inhibited by the nonhydrolyzable GDP analog guanosine 5′-O-(β-
作者: 否認(rèn)    時(shí)間: 2025-3-26 04:11

作者: 整潔漂亮    時(shí)間: 2025-3-26 05:07

作者: TIA742    時(shí)間: 2025-3-26 11:20
Regulation of Myosin Light Chain Kinase Activity in Smooth Muscle,tractility. The quantitative relation between intracellular Ca. concentrations and light chain phosphorylation is not fixed but modulated dynamically by various regulatory processes. Most of the calmodulin in smooth muscle cells is tightly bound to cellular elements even in the absence of Ca.. Surpr
作者: 柔美流暢    時(shí)間: 2025-3-26 12:57
Actin-Binding Property of Myosin Light Chain Kinase and Its Role in Regulating Actin-Myosin Interacto the kinase activity innate in MLCK. We have found that this property exerts an inhibitory effect on the ATP-dependent interaction between actin and myosin. The N-terminal, actin-binding fragment was responsible for the inhibition. Calmodulin in the presence of Ca. (Ca./CaM) efficiently relieved t
作者: GLOSS    時(shí)間: 2025-3-26 18:05
Pharmacomechanical Coupling Through Regulation of Myosin Light Chain Phosphatase,ibed. Desensitization of phasic smooth muscles to Ca. is demonstrated through time-dependent divergence, during relaxation, between the level of Ca. and the decline in MLC. phosphorylation and force. Possible mechanisms of desensitization include down-regulation of myosin light chain kinase and up-r
作者: 主動    時(shí)間: 2025-3-26 21:34
Smooth Muscle Myosin Phosphatase,e was active with both isolated myosin light chain and intact myosin that had been phosphorylated by myosin light chain kinase as substrates, suggesting that phosphorylated myosin might be a substrate in situ. The 38-kDa subunit was identified as a catalytic subunit of a type lδ protein phosphatase
作者: Tailor    時(shí)間: 2025-3-27 04:46
Structure and Expression of Vascular Smooth Muscle Calponin,(SMCs). The NH.-terminal region of calponin shares homology with a putative negative regulatory domain of the GDP-GTP exchanger for Rho-like GTP-binding proteins. Expression of calponin is down-modulated in proliferating SMCs of atherosclerotic neointima and injured arterial media. Direct transfer o
作者: Electrolysis    時(shí)間: 2025-3-27 07:49

作者: frenzy    時(shí)間: 2025-3-27 11:29
Smooth Muscle Cell Differentiation and Its Abnormality in Vascular Diseases,h muscles contain at least three MHC isoforms: SM1 (204 kDa), SM2 (200 kDa), and SMemb (200 kDa). SM1 and SM2 are specific to smooth muscles. SM1 is expressed from the early stage of fetal life into adulthood, but SM2 appears after birth. SMemb is a nonmuscle-type MHC abundantly expressed in the emb
作者: 敲詐    時(shí)間: 2025-3-27 16:07

作者: modish    時(shí)間: 2025-3-27 20:08

作者: 性別    時(shí)間: 2025-3-27 22:33

作者: conflate    時(shí)間: 2025-3-28 03:27

作者: 縫紉    時(shí)間: 2025-3-28 09:02

作者: Horizon    時(shí)間: 2025-3-28 11:15

作者: Conscientious    時(shí)間: 2025-3-28 16:29

作者: d-limonene    時(shí)間: 2025-3-28 19:55
Cross-Bridge Cycle in Phasic and Tonic Smooth Muscle,the cross-bridge cycle is presented. (5) The affinity of cross-bridges for MgADP is much higher in tonic than in phasic smooth muscles. (6) Creatine phosphate (CP) accelerates relaxation induced by flash photolysis of Diazo-2 in isometrically contracted, permeabilized smooth muscle. We suggest that
作者: 煉油廠    時(shí)間: 2025-3-28 22:58

作者: 巧辦法    時(shí)間: 2025-3-29 06:28
Regulation of Ca2+-Dependent Phosphorylation of 20-kDa Myosin Light Chain by the Small Molecular Wethe botulinum exoenzyme C., which specifically ADP-ribosylates and inactivates the rho family proteins, completely abolishes GTPγS-induced enhancement of Ca.-dependent MLC. phosphorylation. Under the same condition C. completely ADP-ribosylates cellular proteins with a relative molecular weight of 2
作者: sultry    時(shí)間: 2025-3-29 10:37
Molecular Dissection of Regulatory Light Chain Function in Vertebrate Smooth Muscle Myosins,emonstrate that the origin of the third subdomain specifies the regulatory capability of the RLC. A series of smooth muscle myosin RLC mutants with deletions in the fourth subdomain show that the C-terminal helix in this subdomain is essential for regulation. Although the skeletal and scallop RLCs n
作者: champaign    時(shí)間: 2025-3-29 12:13
Autoinhibition of Myosin Light Chain Kinase,bition. These results required reevaluation of the pseudosubstrate hypothesis. Based on a model showing the interaction of the pseudosubstrate sequence with the catalytic core, Y. interacts with a hydrophobic pocket in the catalytic core. We propose that this interaction is enough to inhibit the enz
作者: 類人猿    時(shí)間: 2025-3-29 19:09
Regulation of Myosin Light Chain Kinase Activity in Smooth Muscle,us of the calmodulin-binding domain. This phosphorylation increases the concentration of Ca./calmodulin required for activation and hence physiologically increases the Ca z concentration required for light chain phosphorylation. However, in smooth muscle cells the concentration of Ca. necessary for
作者: 公理    時(shí)間: 2025-3-29 22:12
Pharmacomechanical Coupling Through Regulation of Myosin Light Chain Phosphatase,osin light chain phosphatase, through dissociation of the catalytic from the targeting subunits, are illustrated, and studies showing the inhibition of voltage-gated Ca“ current by arachidonic acid are summarized. It is suggested that G protein-coupled protein phosphatase inhibition plays a signific
作者: nullify    時(shí)間: 2025-3-30 00:51
Smooth Muscle Myosin Phosphatase,er and skeletal muscle, and higher concentrations of the 130-kDa component were found in samples of smooth muscle. Intact myosin phosphatase was purified from chicken gizzard with the MoAb as probe. The purified holoenzyme was a heterotrimer that consisted of PP1bc (38kDa) and regulatory subunits of
作者: 橫截,橫斷    時(shí)間: 2025-3-30 04:56
Modulation of Vascular Smooth Muscle Contraction by Calponin Phosphorylation, of .P incorporation into the calponin in association with the development of force. These results suggest that calponin phosphorylation by protein kinase C plays a potential role in the modulation of smooth muscle contraction by agonists.
作者: endure    時(shí)間: 2025-3-30 11:52

作者: 填滿    時(shí)間: 2025-3-30 12:41

作者: frivolous    時(shí)間: 2025-3-30 19:31
he approach is broad and presents contemporary opinions in pharmacology, physiology, and biochemistry as they relate to smooth muscle function. The book will appeal not only to those working in these disciplines, but to vascular clinicians, obstetric-gynecological physicians, and gastroenterologists as well.978-4-431-65882-5978-4-431-65880-1
作者: eucalyptus    時(shí)間: 2025-3-30 20:42
tification, postmortem changes, and the entire range of case types, ranging from natural deaths to drug-related deaths to various types of violent death. The text is written in easy-to-understand language, and is complemented by hundreds of high-quality photographs..978-1-62703-818-8978-1-59745-404-9




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