標(biāo)題: Titlebook: Recombinant Technology in Hemostasis and Thrombosis; Leon W. Hoyer,William N. Drohan Book 1991 Springer Science+Business Media New York 19 [打印本頁] 作者: TEMPO 時(shí)間: 2025-3-21 18:49
書目名稱Recombinant Technology in Hemostasis and Thrombosis影響因子(影響力)
書目名稱Recombinant Technology in Hemostasis and Thrombosis影響因子(影響力)學(xué)科排名
書目名稱Recombinant Technology in Hemostasis and Thrombosis網(wǎng)絡(luò)公開度
書目名稱Recombinant Technology in Hemostasis and Thrombosis網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Recombinant Technology in Hemostasis and Thrombosis被引頻次
書目名稱Recombinant Technology in Hemostasis and Thrombosis被引頻次學(xué)科排名
書目名稱Recombinant Technology in Hemostasis and Thrombosis年度引用
書目名稱Recombinant Technology in Hemostasis and Thrombosis年度引用學(xué)科排名
書目名稱Recombinant Technology in Hemostasis and Thrombosis讀者反饋
書目名稱Recombinant Technology in Hemostasis and Thrombosis讀者反饋學(xué)科排名
作者: 小溪 時(shí)間: 2025-3-21 21:42
Molecular Defects in Hemophilia Brm whereas factor VIII is consumed. Marked genetic heterogeneity among different families with hemophilia B was suggested from comparison of factor IX antigen levels with clotting activities. In patients from different families, specific activities were usually distinctly different..作者: Myosin 時(shí)間: 2025-3-22 02:09 作者: Foam-Cells 時(shí)間: 2025-3-22 04:50
Factor IX: Gene Structure and Protein Synthesis of the human factor IX gene, and discuss the various approaches to producing recombinant factor IX as a pharmaceutical. The molecular genetics of factor IX deficiency (hemophilia B) are discussed elsewhere in this book. The molecular biology and molecular genetics of blood coagulation have been reviewed recently..作者: 沖突 時(shí)間: 2025-3-22 11:47
Antithrombin III Genetics, Structure and Functionchiometric ATIII-enzyme complexes form as a result of interactions between the reactive site of ATIII and the active site of the protease target.. The rate of complex formation increases substantially in the presence of heparan sulfate proteoglycans on the surface of the vascular endothelium .,. or after addition of heparin . or pharmaceutically..作者: Herd-Immunity 時(shí)間: 2025-3-22 15:56 作者: 出沒 時(shí)間: 2025-3-22 17:37
thrombosis. The goal of the XXI Annual Scientific Symposium of the American Red Cross was to provide a forum to explore and document the impact of recombinant DNA technology in this field. The speakers described the essential features of the genes responsible for key plasma proteins important in he作者: 彈藥 時(shí)間: 2025-3-22 21:54
Biosynthesis and Assembly of the Factor VIII-Von Willebrand Factor Complexcofactor in the intrinsic coagulation pathway (1, 2) whereas vWF is hemostatically important in the mediation of platelet-vessel wall interactions at sites of vascular injury (3, 4). In blood, factor VIII and vWF are not present as distinct proteins but rather circulate as a linked complex. Several 作者: 饑荒 時(shí)間: 2025-3-23 03:38
Factor IX: Gene Structure and Protein Synthesisques, DNA fragments can be cloned and characterized at the molecular level. This in turn led to the discovery of intervening sequences in some eukaryotic genes, the identification of promoter elements, and to the production of recombinant proteins. As with many other fields, the field of thrombosis 作者: 提名 時(shí)間: 2025-3-23 08:52 作者: 得罪 時(shí)間: 2025-3-23 11:00
Interactions Between The Functional Domains of Antithrombin III occurs following cleavage of the Arg.-Ser. peptide bond and formation of a stable complex between this reactive site arginine of antithrombin III and the active site serine of the protease.. Antithrombin III is a member of a superfamily of protease inhibitors. designated as serine protease inhibito作者: extinguish 時(shí)間: 2025-3-23 14:49
Protein C: Gene Structure and Protein Synthesisa feedback down-regulator of the coagulation cascade by specifically degrading the protein cofactors VIIIa and Va (Figure 1). The biological role of protein C and the vascular endothelium has been recently reviewed in a succinct fashion.. Protein C in a less understood manner also enhances the proce作者: Fierce 時(shí)間: 2025-3-23 20:51 作者: 走調(diào) 時(shí)間: 2025-3-24 01:37
Molecular Defects in Hemophilia A, and when characterized by procoagulant or immunologic assays, it is a heterogeneous disorder. However, disease severity usually corresponds to the extent of factor VIII deficiency.. Severe hemophilia with recurrent hemarthroses usually means that there is no detectable plasma factor VIII (< 1% of 作者: 孤僻 時(shí)間: 2025-3-24 04:58 作者: 厚臉皮 時(shí)間: 2025-3-24 08:37 作者: 一大群 時(shí)間: 2025-3-24 12:11 作者: 牽連 時(shí)間: 2025-3-24 18:23 作者: 600 時(shí)間: 2025-3-24 20:32
Synthesis of Biologically Active Vitamin K-Dependent Coagulation Factors thrombosis. In particular, there has been interest in producing recombinant factor IX for treatment of hemophilia B, factor VII for treatment of hemophilia A patients with inhibitors and recombinant protein C for treatment of thrombotic disorders. Since these proteins undergo a unique posttranslati作者: 聯(lián)想 時(shí)間: 2025-3-25 02:33
The Expression of Therapeutic Proteins in Transgenic Animals, albumin, immunoglobulins, fibrinogen and protein C are routinely isolated from human plasma. Improved protein isolation and viral inactivation techniques have led to the production of purer and safer plasma derivatives, although in some cases in quantities insufficient to meet patient needs.作者: Lament 時(shí)間: 2025-3-25 05:52
The Use of Animal Models to Evaluate Proteins Produced by Recombinant Technology testing of new therapies in animals is required by many regulatory jurisdictions to provide both the justification for human study and information upon which the design of these studies will be based. Moreover, in more traditional pharmaceuticals, In vivo evaluations in appropriate animal models ha作者: ATOPY 時(shí)間: 2025-3-25 07:31 作者: TIGER 時(shí)間: 2025-3-25 12:34
978-1-4613-6644-7Springer Science+Business Media New York 1991作者: Ovulation 時(shí)間: 2025-3-25 15:56 作者: 無價(jià)值 時(shí)間: 2025-3-25 23:43
http://image.papertrans.cn/r/image/824108.jpg作者: 沖突 時(shí)間: 2025-3-26 02:13
https://doi.org/10.1007/978-1-4615-3698-7DNA; biology; genes; molecular biology; mutation; plasma; protein; proteins; thrombosis作者: 去才蔑視 時(shí)間: 2025-3-26 04:39
e. The long university training of physicians in the sciences, as well as contemporary technological visions of modern medical practices, provided important symbolic resources for physicians who wanted to convince the lay public of their competence as modern experts. However, such modern images of m作者: Decimate 時(shí)間: 2025-3-26 11:18
ourse, on the one hand, and the positions and strategies of experts, on the other. For the comparative case study presented here, I have argued that there are specific linkages between field and actor in the American and German family debates that are related to the adversarial and inquisitorial mod作者: Corporeal 時(shí)間: 2025-3-26 14:17
Jan A. van Mourik,Anja Leyte,Harm B. van Schijndel,Martin Ph. Verbeet,Jan Voorberg,Ruud D. Fonteijn,e. The long university training of physicians in the sciences, as well as contemporary technological visions of modern medical practices, provided important symbolic resources for physicians who wanted to convince the lay public of their competence as modern experts. However, such modern images of m作者: 吼叫 時(shí)間: 2025-3-26 18:01
D. B. C. Ritchie,D. L. Robertson,R. T. A. MacGillivraye. The long university training of physicians in the sciences, as well as contemporary technological visions of modern medical practices, provided important symbolic resources for physicians who wanted to convince the lay public of their competence as modern experts. However, such modern images of m作者: 溫室 時(shí)間: 2025-3-27 00:48 作者: reception 時(shí)間: 2025-3-27 01:32
Paula R. Boerger,Robert M. Wolcott,Morgan Lorio,Michael N. Blackburnourse, on the one hand, and the positions and strategies of experts, on the other. For the comparative case study presented here, I have argued that there are specific linkages between field and actor in the American and German family debates that are related to the adversarial and inquisitorial mod作者: Fermentation 時(shí)間: 2025-3-27 08:03
George L. Longourse, on the one hand, and the positions and strategies of experts, on the other. For the comparative case study presented here, I have argued that there are specific linkages between field and actor in the American and German family debates that are related to the adversarial and inquisitorial mod作者: 反叛者 時(shí)間: 2025-3-27 11:21 作者: 卡死偷電 時(shí)間: 2025-3-27 15:00 作者: 提煉 時(shí)間: 2025-3-27 19:36 作者: miracle 時(shí)間: 2025-3-28 01:01
Arthur R. Thompsone. The long university training of physicians in the sciences, as well as contemporary technological visions of modern medical practices, provided important symbolic resources for physicians who wanted to convince the lay public of their competence as modern experts. However, such modern images of m作者: 勤勞 時(shí)間: 2025-3-28 02:06 作者: 鞏固 時(shí)間: 2025-3-28 09:46 作者: chondromalacia 時(shí)間: 2025-3-28 10:52 作者: 空氣傳播 時(shí)間: 2025-3-28 16:14 作者: 榮幸 時(shí)間: 2025-3-28 21:12 作者: 頭腦冷靜 時(shí)間: 2025-3-29 02:19 作者: 假裝是我 時(shí)間: 2025-3-29 04:25 作者: 和諧 時(shí)間: 2025-3-29 09:29 作者: Obituary 時(shí)間: 2025-3-29 12:31 作者: Maximizer 時(shí)間: 2025-3-29 17:38
Interactions Between The Functional Domains of Antithrombin III different despite the fact that each of these enzymes displays selectivity for cleavage at arginine side chains. At present, it is not clear what structural features, in addition to the amino acid sequence at the p1 and p1’ positions, determine the kinetics of protease-inhibitor docking and the sta作者: 眉毛 時(shí)間: 2025-3-29 21:58
Structural and Functional Properties of Protein C treatment of prothrombin with thrombin could elicit an inhibitor of coagulation. This led to the inhibitor’s characterization and designation as autoprothrombin IIa (2). Marciniak (3) confirmed the observation and noted that the inhibitor was species specific. Some time later, Stenflo characterized作者: 斷斷續(xù)續(xù) 時(shí)間: 2025-3-30 01:24 作者: 陶瓷 時(shí)間: 2025-3-30 05:23 作者: 使尷尬 時(shí)間: 2025-3-30 08:35 作者: GUILE 時(shí)間: 2025-3-30 16:08 作者: endure 時(shí)間: 2025-3-30 19:41 作者: notification 時(shí)間: 2025-3-30 21:06 作者: 笨拙的你 時(shí)間: 2025-3-31 01:14
Book 1991 these advances have made it possible to better characterize hemostatic disorders. A large number of published studies have shown that the mutations affecting biological activity are clustered in areas that define functional domains. They have led to fundamental advances in our understanding of spec作者: thalamus 時(shí)間: 2025-3-31 06:06
same time, these advances have made it possible to better characterize hemostatic disorders. A large number of published studies have shown that the mutations affecting biological activity are clustered in areas that define functional domains. They have led to fundamental advances in our understanding of spec978-1-4613-6644-7978-1-4615-3698-7
