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標(biāo)題: Titlebook: Receptor/Ligand Sorting Along the Endocytic Pathway; Jennifer J. Linderman,Douglas A. Lauffenburger Book 1989 Springer-Verlag Berlin Heide [打印本頁]

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書目名稱Receptor/Ligand Sorting Along the Endocytic Pathway影響因子(影響力)




書目名稱Receptor/Ligand Sorting Along the Endocytic Pathway影響因子(影響力)學(xué)科排名




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Book 1989 separated and routed along different intracellular pathways; this is a critical step in the process of receptor-mediated endocytosis. The development of an understanding of the basic mechanisms of this separation process is presented, with an emphasis on discovering the fundamental and measurable p
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Introduction and Overview,immediate release to the environment, packaged into vesicles for later release to the environment upon the receipt of an appropriate stimulus, incorporated into the cell membrane or into organelle membranes, delivered to lysosomes to function there as enzymes, or delivered to other organelles. Molec
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Simple Kinetic Models of Sorting,n experimentally observed in several systems. In addition, this scheme does not allow for a variety of outcomes of the sorting process, as suggested by experimental data discussed later in this text (Chapters 5 and 6). Furthermore, it is not known whether the kinetics of ligand and receptor movement
作者: ABHOR    時(shí)間: 2025-3-23 08:05
A Whole Cell Kinetic Model of the Endocytic Cycle: Focus on Sorting,e endosome. The most successful of these mechanisms, in terms of explaining the efficient recycling of receptors from the endosome back to the cell surface, suggested that receptors diffuse from the endosomal vesicles into tubules and are trapped there and that during this time ligand molecules equi
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A Kinetic Model of Sorting that Predicts Ligand Effects, sorting. Although this mechanism is successful in explaining the kinetics and efficiency of receptor recycling in many systems, the mechanism allowed for variations in the sorting outcome only as a result of variations in the values of the vesicle radius R, the tubule radius b, the distribution of
作者: 輕推    時(shí)間: 2025-3-23 16:06
Conclusions, targets molecules to their final destinations. By controlling the fraction of internalized receptors that recycle to the cell surface, the cell can regulate its ability to bind extracellular ligand and can thus modulate its response to a particular ligand. Similarly, a cell may choose to degrade li
作者: 縫紉    時(shí)間: 2025-3-23 21:32
A Kinetic Model of Sorting that Predicts Ligand Effects, for variations in the sorting outcome only as a result of variations in the values of the vesicle radius R, the tubule radius b, the distribution of volume between the endosome vesicle and tubules, the diffusion coefficient of the receptor D., the dimensionless current β, the partition coefficient κ, and the sorting time τ*.
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Jennifer J. Linderman,Douglas A. Lauffenburgereveloped; it recommends stocks that fit the strategy of investors, and its recommendations are explainable for investment advisers..978-3-030-75523-2978-3-030-75521-8Series ISSN 1860-949X Series E-ISSN 1860-9503
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Jennifer J. Linderman,Douglas A. Lauffenburgereveloped; it recommends stocks that fit the strategy of investors, and its recommendations are explainable for investment advisers..978-3-030-75523-2978-3-030-75521-8Series ISSN 1860-949X Series E-ISSN 1860-9503
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Jennifer J. Linderman,Douglas A. Lauffenburger is proposed for predicting misinformation spread by leveraging GraphSAGE with heterogeneous graph convolution. Secondly, we propose an explanation module that uses gradient-based and perturbation-based methods, to identify what makes misinformation spread by explaining the trained prediction module
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Jennifer J. Linderman,Douglas A. Lauffenburgeramples to illustrate the practical applications of XAI in manufacturing. It is a valuable resource for researchers, engineers, and practitioners working in the field of AI and manufacturing..978-3-031-27960-7978-3-031-27961-4Series ISSN 2191-530X Series E-ISSN 2191-5318
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Lecture Notes in Biomathematicshttp://image.papertrans.cn/r/image/823563.jpg
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An Equilibrium Model of the Sorting Process,eceptors may be recycled to the cell surface, while much of the ligand is routed to lysosomes. To explain the segregation of the receptor and ligand populations, we first consider a simple equilibrium mechanism based on the geometry of the endosome.
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when making the decisions. Online social networks have a problem with misinformation which is known to have negative effects. In this paper, we propose to utilize XAI techniques to study what factors lead to misinformation spreading by explaining a trained graph neural network that predicts misinfo
作者: 真實(shí)的你    時(shí)間: 2025-3-27 06:29
Jennifer J. Linderman,Douglas A. Lauffenburger when making the decisions. Online social networks have a problem with misinformation which is known to have negative effects. In this paper, we propose to utilize XAI techniques to study what factors lead to misinformation spreading by explaining a trained graph neural network that predicts misinfo
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Jennifer J. Linderman,Douglas A. Lauffenburgerusal structure learning algorithms. GCA generates an explanatory graph from high-level human-interpretable features, revealing how these features affect each other and the black-box output. We show how these high-level features do not always have to be human-annotated, but can also be computationall
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Jennifer J. Linderman,Douglas A. Lauffenburger the main idea of the explainable recommenders outlined with.The book proposes techniques, with an emphasis on the financial sector, which will make recommendation systems both accurate and explainable. The vast majority of AI models work like black box models. However, in many applications, e.g., m




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