標(biāo)題: Titlebook: Receptor-Receptor Interactions in the Central Nervous System; KJELL FUXE,Dasiel O. Borroto-Escuela Book 2018 Springer Science+Business Med [打印本頁(yè)] 作者: indulge 時(shí)間: 2025-3-21 17:51
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作者: Merited 時(shí)間: 2025-3-21 20:57 作者: Asperity 時(shí)間: 2025-3-22 04:16 作者: facilitate 時(shí)間: 2025-3-22 08:30 作者: bronchodilator 時(shí)間: 2025-3-22 11:01 作者: 鎮(zhèn)壓 時(shí)間: 2025-3-22 14:10 作者: FUSC 時(shí)間: 2025-3-22 18:56
Davide Lattanzi,David Savelli,Michael Di Palma,Stefano Sartini,Silvia Eusebi,Dasiel O. Borroto-Escuegle instance predictions with XAI.Includes best practices foUnderstand how to use Explainable AI (XAI) libraries and build trust in AI and machine learning models. This book utilizes a problem-solution approach to explaining machine learning models and their algorithms.?.The book starts with model i作者: 翅膀拍動(dòng) 時(shí)間: 2025-3-23 00:59
Sergio Tanganelli,Tiziana Antonelli,Sarah Beggiato,Maria Cristina Tomasini,Kjell Fuxe,Dasiel O. Borr question answering, legal texts or news summarization, and headline generation systems. The explosion in the amount of text data from various sources in the context of the big data and 4.0 industrial revolution era demands innovative automatic text summarization techniques, formerly thought unattai作者: 愛(ài)哭 時(shí)間: 2025-3-23 02:58 作者: 極為憤怒 時(shí)間: 2025-3-23 07:10 作者: LINES 時(shí)間: 2025-3-23 10:41 作者: cataract 時(shí)間: 2025-3-23 16:11
Ping Su,Frankie H. F. Lee,Fang Liu intelligence (AI) techniques that do not explain their reco.This book focuses on an overview of the AI techniques, their foundations, their applications, and remaining challenges and open problems. Many artificial intelligence (AI) techniques do not explain their recommendations. Providing natural-作者: RAGE 時(shí)間: 2025-3-23 22:01 作者: 鉤針織物 時(shí)間: 2025-3-23 22:45 作者: 招募 時(shí)間: 2025-3-24 02:56 作者: gait-cycle 時(shí)間: 2025-3-24 06:50 作者: Mechanics 時(shí)間: 2025-3-24 12:13
Maxwell S. DeNies,Luciana K. Rosselli-Murai,Victoria L. Murray,Elisabeth M. Steel,Allen P. Liu, ., 71(12):3308–3321, 2022; Pan and Mishra, ., pages 24–34. IEEE, 2021; Pan and Mishra, Hardware trojan detection using Shapley ensemble boosting, pages 1127–1130, 2021; Pan and Mishra, ., 10:49508–49527, 2022). However, DNNs are usually not suitable for safety-critical applications since DNNs can 作者: 凝結(jié)劑 時(shí)間: 2025-3-24 16:13
Pavel Powlowski,Kyla Bourque,Jace Jones-Tabah,Rory Sleno,Dominic Devost,Terence E. Hébertetection approaches are promising in various domains due to their scalability as well as detection accuracy Arp et al. (Effective and efficient malware detection at the end host. In: 18th USENIX. Montreal, Quebec, 2009); Dahl et al. (Large-scale malware classification using random projections and ne作者: 有抱負(fù)者 時(shí)間: 2025-3-24 20:04
Ismel Brito,Manuel Narvaez,David Savelli,Kirill Shumilov,Michael Di Palma,Stefano Sartini,Kamila Ski, ., 71(12):3308–3321, 2022; Pan and Mishra, ., pages 24–34. IEEE, 2021; Pan and Mishra, Hardware trojan detection using Shapley ensemble boosting, pages 1127–1130, 2021; Pan and Mishra, ., 10:49508–49527, 2022). However, DNNs are usually not suitable for safety-critical applications since DNNs can 作者: Tidious 時(shí)間: 2025-3-25 02:37
Dasiel O. Borroto-Escuela,Manuel Narvaez,Ismael Valladolid-Acebes,Kirill Shumilov,Michael Di Palma,K, ., 71(12):3308–3321, 2022; Pan and Mishra, ., pages 24–34. IEEE, 2021; Pan and Mishra, Hardware trojan detection using Shapley ensemble boosting, pages 1127–1130, 2021; Pan and Mishra, ., 10:49508–49527, 2022). However, DNNs are usually not suitable for safety-critical applications since DNNs can 作者: JAUNT 時(shí)間: 2025-3-25 06:39 作者: 表被動(dòng) 時(shí)間: 2025-3-25 11:29 作者: 我邪惡 時(shí)間: 2025-3-25 12:46
Manuel Narvaez,Fidel Corrales,Ismel Brito,Ismael Valladolid-Acebes,Kjell Fuxe,Dasiel O. Borroto-Escut narrative of politicisation is shown to be a byproduct of this entanglement, analysed through tropes of ‘feedback loops’ and nostalgia. This encounter sets the scene for experts’ conditions of possibility within the World Heritage regime as they navigate their role in relation to both protection a作者: ostrish 時(shí)間: 2025-3-25 19:52
Alicia Rivera,Alejandra Valderrama-Carvajal,Diana Suárez-Boomgaard,Kirill Shumilov,M. ángeles Real,K that can tell us about the role of the expert today will be of interest to students and scholars across the history of science, the sociology of knowledge, future studies, the history of the Cold War, social science methodology, and social policy.?.978-3-030-32783-5978-3-030-32781-1Series ISSN 2946-4919 Series E-ISSN 2946-4927 作者: harbinger 時(shí)間: 2025-3-25 20:45
Sarah Beggiato,Sergio Tanganelli,Tiziana Antonelli,Maria Cristina Tomasini,Kjell Fuxe,Dasiel O. Borr that can tell us about the role of the expert today will be of interest to students and scholars across the history of science, the sociology of knowledge, future studies, the history of the Cold War, social science methodology, and social policy.?.978-3-030-32783-5978-3-030-32781-1Series ISSN 2946-4919 Series E-ISSN 2946-4927 作者: obsession 時(shí)間: 2025-3-26 04:13 作者: mendacity 時(shí)間: 2025-3-26 05:12
Miguel Pérez de la Mora,José del Carmen Rejón-Orantes,Minerva Crespo-Ramírez,Dasiel O. Borroto-Escuenerated summaries. Conducted experiments show that our approach’s scores are highly positively correlated to the state-of-the-art ROUGE ones. This research’s salient outcome is that it proposes a cognitive and explainable model of AGSE, and it pushes toward cognitive natural language processing. It 作者: Boycott 時(shí)間: 2025-3-26 10:18 作者: falsehood 時(shí)間: 2025-3-26 14:31 作者: nautical 時(shí)間: 2025-3-26 17:11 作者: 慢跑鞋 時(shí)間: 2025-3-26 21:23
Irene Reyes-Resina,Eva Martínez-Pinilla,Dasiel O. Borroto-Escuela,Kjell Fuxe,Gemma Navarro,Rafael Frn technique for spectral normalization based on Fourier transform and layer separation. The proposed method provides DNNs with promising security protection while maintaining minimized time cost, which turns SN from a theoretically feasible approach to a practically useful framework. Experimental ev作者: 娘娘腔 時(shí)間: 2025-3-27 04:39 作者: 感情 時(shí)間: 2025-3-27 08:34 作者: WATER 時(shí)間: 2025-3-27 11:34
Elise Wouters,Lakshmi Vasudevan,Francisco Ciruela,Deepak K. Saini,Christophe Stove,Kathleen Van Craen technique for spectral normalization based on Fourier transform and layer separation. The proposed method provides DNNs with promising security protection while maintaining minimized time cost, which turns SN from a theoretically feasible approach to a practically useful framework. Experimental ev作者: 蒸發(fā) 時(shí)間: 2025-3-27 14:00
Maxwell S. DeNies,Luciana K. Rosselli-Murai,Victoria L. Murray,Elisabeth M. Steel,Allen P. Liun technique for spectral normalization based on Fourier transform and layer separation. The proposed method provides DNNs with promising security protection while maintaining minimized time cost, which turns SN from a theoretically feasible approach to a practically useful framework. Experimental ev作者: Sleep-Paralysis 時(shí)間: 2025-3-27 20:55 作者: 衰弱的心 時(shí)間: 2025-3-27 23:24 作者: SLUMP 時(shí)間: 2025-3-28 03:00
Dasiel O. Borroto-Escuela,Manuel Narvaez,Ismael Valladolid-Acebes,Kirill Shumilov,Michael Di Palma,Kn technique for spectral normalization based on Fourier transform and layer separation. The proposed method provides DNNs with promising security protection while maintaining minimized time cost, which turns SN from a theoretically feasible approach to a practically useful framework. Experimental ev作者: Tremor 時(shí)間: 2025-3-28 09:18 作者: Initial 時(shí)間: 2025-3-28 13:28
Valentina Di Liberto,Giuseppa Mudó,Dasiel O. Borroto-Escuela,Kjell Fuxe,Natale Belluardoation attribution.? ?.After reading this book, you will understand AI and machine learning models and be able to put that knowledge into practice to bring more accuracy and transparency to your analyses..What Y978-1-4842-9028-6978-1-4842-9029-3作者: NATAL 時(shí)間: 2025-3-28 17:36 作者: 純樸 時(shí)間: 2025-3-28 20:29
,Analysis and Quantification of GPCR Allosteric Receptor–Receptor Interactions Using Radioligand Bining site. In view of the complex nature of allosteric mechanisms, the detection, analysis, and quantification of the effects of this phenomenon rely on the use of competition radioligand binding assays to ensure proper demonstration of the high and low affinity D2R agonist binding sites. Outlined in作者: 變形 時(shí)間: 2025-3-29 02:57 作者: 脫離 時(shí)間: 2025-3-29 06:16
,Electrophysiological Approach to GPCR–RTK Interaction Study in Hippocampus of Adult Rats,–RTK interaction in hippocampus CA1 pyramidal neurons of adult rat, paying particular attention to highlight major problems that can occur using this technique and providing useful troubleshooting steps to achieve reliable results.作者: 說(shuō)不出 時(shí)間: 2025-3-29 08:03
Double Fluorescent Knock-In Mice to Investigate Endogenous Mu-Delta Opioid Heteromer Subcellular Di in which the MOP-DOP heteromers are expressed. Here, we describe a method to quantitatively and automatically analyze changes in the subcellular distribution of MOP-DOP heteromers in primary hippocampal culture from this mouse model. This approach provides a unique tool to address specificities of 作者: 極深 時(shí)間: 2025-3-29 12:15
Biochemical Characterization of Dopamine D2 Receptor-Associated Protein Complexes Using Co-ImmunoprDISC1 interactions and discussed their association in the pathophysiology of schizophrenia. This chapter aims to provide systemic guidelines for the standard biochemical techniques in identifying D2R-associated protein–protein interactions, and to investigate the roles of these interactions in the b作者: 剝削 時(shí)間: 2025-3-29 16:47 作者: 忙碌 時(shí)間: 2025-3-29 23:48
Bimolecular Fluorescence Complementation Methodology to Study G Protein-Coupled Receptor Dimerizatiy fusing the fragments to two interacting proteins. The advantage of BiFC over alternative resonance energy transfer techniques is a high signal-to-noise ratio due to its strong intrinsic fluorescence without exogenous fluorogenic or chromogenic agents required. Here we provide a detailed descriptio作者: FAST 時(shí)間: 2025-3-30 02:17 作者: interpose 時(shí)間: 2025-3-30 05:55
Assessing GPCR Dimerization in Living Cells: Comparison of the NanoBiT Assay with Related Bioluminells. Interestingly, most of the approaches employ noninvasive fluorescence- and luminescence-based assays. Here, we present an efficient strategy to study GPCR dimerization dynamics, namely a protein complementation assay (PCA) based on the reconstitution of a luminescent protein, the NanoLuciferase作者: chondromalacia 時(shí)間: 2025-3-30 11:38 作者: badinage 時(shí)間: 2025-3-30 14:43
Searching the GPCR Heterodimer Network (GPCR-hetnet) Database for Information to Deduce the Receptoknet, and the ionnet. Other supporting datasets include information about receptors that are present in GPCR-hetnet such as literature citations. This chapter describes in a basic protocol how to use, navigate, and browse through the GPCR-hetnet database to identify the clusters in which a receptor 作者: evince 時(shí)間: 2025-3-30 19:11
Detection, Analysis, and Quantification of GPCR Homo- and Heteroreceptor Complexes in Specific Neurs. Therefore, the detection and visualization of GPCR homo- and heteroreceptor complexes in the brain remained largely unknown until recent years, when a well-characterized in situ proximity ligation assay (in situ PLA) was adapted to validate the receptor complexes in their native environment. The 作者: 苦惱 時(shí)間: 2025-3-31 00:38 作者: PATHY 時(shí)間: 2025-3-31 03:36 作者: Cirrhosis 時(shí)間: 2025-3-31 06:41 作者: Metastasis 時(shí)間: 2025-3-31 11:56
,In Vivo Microdialysis Technique Applications to Understand the Contribution of Receptor–Receptor Ins mainly focused on a general description of microdialysis technique in freely moving animals and on the application of one- or dual-probe(s) microdialysis to investigate the functional relevance of receptor–receptor interactions in rodent brain.作者: 公司 時(shí)間: 2025-3-31 14:10 作者: neologism 時(shí)間: 2025-3-31 19:04
Proximity Biotinylation for Studying G Protein-Coupled Receptor Dimerization,nt this new approach to study GPCR dimerization. Finally, we will compare and contrast the advantages and limitations of the proximity biotinylation assay with established methods to help researchers identify the best approach for their research application.作者: 死貓他燒焦 時(shí)間: 2025-3-31 23:00 作者: Proclaim 時(shí)間: 2025-4-1 03:27 作者: Ingrained 時(shí)間: 2025-4-1 07:51 作者: caldron 時(shí)間: 2025-4-1 12:24
Small Interference RNA Knockdown Rats in Behavioral Functions: GALR1/GALR2 Heteroreceptor in Anxietgenerated siRNA GALR1 and siRNA GALR2 rats to analyze the involvement of GALR1-GALR2 heteroreceptor complexes in the behavioral effects induced by GAL(1–15). In this chapter, we provide a protocol for using these animal models to investigate the role of heterodimers in vivo when a behavioral test is needed.作者: Heart-Rate 時(shí)間: 2025-4-1 16:30 作者: 水槽 時(shí)間: 2025-4-1 20:43 作者: overhaul 時(shí)間: 2025-4-2 00:17
,On the Study of D4R-MOR Receptor–Receptor Interaction in the Rat Caudate Putamen: Relevance on Morp as starting point: (1) quantitative receptor autoradiography (saturation assay); (2) agonist-stimulated [.S]GTPγS binding in autoradiography; and (3) immunohistochemistry. Together, they allow to explore functional changes in receptors signaling transduction, i.e., receptor recognition, G protein a作者: 致詞 時(shí)間: 2025-4-2 03:01
,Use of Superfused Synaptosomes to Understand the Role of Receptor–Receptor Interactions as Integrat been extensively used to study the mechanism of neurotransmitter release in vitro because they preserve the biochemical, morphological, and electrophysiological properties of the synapse. This allows an unequivocal interpretation of results obtained under accurately specified experimental condition作者: FLOAT 時(shí)間: 2025-4-2 07:28
Detection of Fibroblast Growth Factor Receptor 1 (FGFR1) Transactivation by Muscarinic Acetylcholinransactivate tyrosine kinase receptors and their downstream intracellular signaling in absence of specific ligands. Here we describe our protocol for dissociating and maintaining hippocampal primary neurons in high- and low-density culture, followed by a description of methods employed to evaluate n
