標(biāo)題: Titlebook: Recent Advances In Retinal Degeneration; Robert E. Anderson,Matthew M. LaVail,Joe G. Hollyf Book 2008 The Editor(s) (if applicable) and Th [打印本頁(yè)] 作者: 適婚女孩 時(shí)間: 2025-3-21 18:29
書目名稱Recent Advances In Retinal Degeneration影響因子(影響力)
書目名稱Recent Advances In Retinal Degeneration影響因子(影響力)學(xué)科排名
書目名稱Recent Advances In Retinal Degeneration網(wǎng)絡(luò)公開度
書目名稱Recent Advances In Retinal Degeneration網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Recent Advances In Retinal Degeneration被引頻次
書目名稱Recent Advances In Retinal Degeneration被引頻次學(xué)科排名
書目名稱Recent Advances In Retinal Degeneration年度引用
書目名稱Recent Advances In Retinal Degeneration年度引用學(xué)科排名
書目名稱Recent Advances In Retinal Degeneration讀者反饋
書目名稱Recent Advances In Retinal Degeneration讀者反饋學(xué)科排名
作者: VEST 時(shí)間: 2025-3-21 21:35
https://doi.org/10.1007/978-0-387-74904-4development; diseases; endothelium; etiology; gene expression; genetics; hearing; inflammation; macular dege作者: entreat 時(shí)間: 2025-3-22 03:14 作者: insular 時(shí)間: 2025-3-22 04:55 作者: 預(yù)防注射 時(shí)間: 2025-3-22 10:43
Robert E. Anderson,Matthew M. LaVail,Joe G. HollyfSpecial focus on mechanism of photoreceptor degeneration and cell death.Includes supplementary material: 作者: brassy 時(shí)間: 2025-3-22 16:37 作者: organic-matrix 時(shí)間: 2025-3-22 19:29
Development of Viral Vectors with Optimal Transgene Expression for Ocular Gene Therapiesrapies using viral vectors are one of the promising technologies. For an ideal therapeutic effect, a variety of vector designs have been tested. Especially, selection of a promoter to drive a transgene is important to obtain adequate level of expression. In this brief chapter, reviewed are the promoters for viral vectors for ocular gene therapies.作者: overbearing 時(shí)間: 2025-3-22 22:23
Curing Blindness with Stem Cells: Hope, Reality, and Challengesta, 2001; Hatakeyama and Kageyama, 2004; Jean et al., 1998; Livesey and Cepko, 2001; Lupo et al., 2000; Malicki, 2004; Marquardt and Gruss, 2002; Rapaport et al., 2004; Vetter and Brown, 2001; Zhang et al., 2002).作者: 教唆 時(shí)間: 2025-3-23 03:00
Nanoceria Particles Prevent ROI-Induced Blindnesside, hypochlorite ions, hydroxyl radicals, hydroxyl ions and superoxide anions (Beatty et al., 2000), react with almost any nearby DNA, RNA, lipid, carbohydrate or protein. They are produced primarily by the normal oxidative metabolism that occurs in the mitochondrial respiratory chain.作者: Entreaty 時(shí)間: 2025-3-23 06:32 作者: Pituitary-Gland 時(shí)間: 2025-3-23 10:30 作者: Contend 時(shí)間: 2025-3-23 17:22 作者: Harness 時(shí)間: 2025-3-23 20:21
In vitro Analysis of Ribozyme-mediated Knockdown of an ADRP Associated Rhodopsin MutationSung et al., 1993; Sung et al., 1991), rhodopsin mutations that are similar to wild-type in terms of expression levels, folding and formation of functional photopigment are considered Class 1 mutations.作者: Condense 時(shí)間: 2025-3-24 00:21
Genetic Supplementation of RDS Alleviates a Loss-of-function Phenotype in C214S Model of Retinitis Phang, Garibaldi, Li, Green, & Zack, 2002). As a membrane glycoprotein located in the disc rim region in the OSs of rods and cones (Connell & Molday, 1990; Molday, Hicks, & Molday, 1987; Travis, Brennan, Danielson, Kozak, & Sutcliffe, 1989).作者: 鑲嵌細(xì)工 時(shí)間: 2025-3-24 05:05
of the Retina in the 4 Years Following rAAV-mediated Gene Transfer in the RPE65 Null Mutation Dog therapy to morphologic findings up to 4 years following the gene transfer. In addition, retinas of affected dogs were examined for histologic correlates of spots and color changes seen by ophthalmoscopy in both treated and untreated affected dogs.作者: 思鄉(xiāng)病 時(shí)間: 2025-3-24 08:43
0065-2598 t of The International Symposium on Retinal Degeneration which has become perhaps the most important research meeting in the field. The topics in this volume explore the etiology, cellular mechanisms, epidemiology, generics, models and potential therapeutic measures for the blinding diseases of reti作者: Gullible 時(shí)間: 2025-3-24 14:35
Curing Blindness with Stem Cells: Hope, Reality, and Challenges which the author presented his personal views of the contributions that the study of retinal cell differentiation during normal embryonic development can make towards overcoming the limitations that have so far prevented curing blindness through stem cell transplantation. The talk was illustratedma作者: 細(xì)節(jié) 時(shí)間: 2025-3-24 16:05
Retinal Degenerations: Planning for the Future95; Attebo et al., 1996; Klaver et al., 1998; Novak-Laus et al., 2002). In the United States an estimated 6 million people have age-related macular degeneration with a decrease in central vision after age 60. About 100,000 people have retinitis pigmentosa or a related disease with loss of side and n作者: ALE 時(shí)間: 2025-3-24 19:44 作者: aspersion 時(shí)間: 2025-3-25 01:36
On the Role of CNTF as a Pontential Therapy for Retinal Degeneration: Dr. Jekyll or Mr. Hyde?. CNTF was initially isolated from the chick eye as a soluble factor that promotes the survival of dissociated ciliary ganglionic neurons of 12-day chick embryos (Adler et al., 1979). Its use as a neuroprotective agent for the retina was first tested in rats 15 years ago in a light-damage model of r作者: canvass 時(shí)間: 2025-3-25 05:33 作者: Tonometry 時(shí)間: 2025-3-25 10:55 作者: MEEK 時(shí)間: 2025-3-25 15:05 作者: 四目在模仿 時(shí)間: 2025-3-25 16:19 作者: stroke 時(shí)間: 2025-3-25 22:34 作者: 領(lǐng)巾 時(shí)間: 2025-3-26 00:24
In vitro Analysis of Ribozyme-mediated Knockdown of an ADRP Associated Rhodopsin Mutationsub divided into 3 classes, autosomal dominant, autosomal recessive, and X- linked RP, where the mutant gene exists on the sex chromosome (X) (Hartong et al., 2006; Wang et al., 2005). Mutations in rhodopsin are the most common cause of the autosomaldominant form of RP (ADRP). More than 100 mutation作者: murmur 時(shí)間: 2025-3-26 08:10 作者: Slit-Lamp 時(shí)間: 2025-3-26 12:12
Development of Viral Vectors with Optimal Transgene Expression for Ocular Gene Therapiesrapies using viral vectors are one of the promising technologies. For an ideal therapeutic effect, a variety of vector designs have been tested. Especially, selection of a promoter to drive a transgene is important to obtain adequate level of expression. In this brief chapter, reviewed are the promo作者: enflame 時(shí)間: 2025-3-26 13:14
Adeno-Associated Viral Vectors and the RetinaThe retina is a prime location for gene therapy because of its accessibility, immune privileged status (Caspi, 2006), and susceptible cell types. Several strategies have been attempted to rescue retinal disease, including gene replacement (Acland et al., 2001), gene knockdown with both ribozymes (Go作者: hieroglyphic 時(shí)間: 2025-3-26 17:26 作者: 紡織品 時(shí)間: 2025-3-26 22:30
of the Retina in the 4 Years Following rAAV-mediated Gene Transfer in the RPE65 Null Mutation Dogvement following a single unilateral subretinal injection of a recombinant adeno-associated virus vector, serotype 2, rAAV2/2, cDNA for dog RPE65 with a cytomegalo virus (CMV) promoter (Narfstr?m et al., 2003a,b, 2005; Ford et al., 2003). The purpose of the present investigation was to further asses作者: meditation 時(shí)間: 2025-3-27 02:51
Virus-mediated Gene Delivery to Neuronal Progenitorsredsson et al., 2006). Degenerations due to recessive mutations can be slowed or prevented by gene augmentation in which the wild-type form of the transgene of interest is packaged into a recombinant virus. Neurotrophic or neuroprotective factors can be delivered to tissues of interest by transducti作者: SYN 時(shí)間: 2025-3-27 05:17
Book 2008ng in the field. The topics in this volume explore the etiology, cellular mechanisms, epidemiology, generics, models and potential therapeutic measures for the blinding diseases of retinitis pigmentosa and age-related macular degeneration...Special focus is highlighted in the areas of Mechanisms of 作者: esthetician 時(shí)間: 2025-3-27 11:09
Virus-mediated Gene Delivery to Neuronal Progenitorson with an appropriate virus. And, in the case of dominant inherited degenerations, a recombinant virus carrying siRNA specific to the mutant transgene could be introduced to the cells of interest to result in decreased production of the dominant negative form of the protein.作者: 生存環(huán)境 時(shí)間: 2025-3-27 16:25
Retinal Degenerations: Planning for the Futuregeneration with a decrease in central vision after age 60. About 100,000 people have retinitis pigmentosa or a related disease with loss of side and night vision in adolescence; they often develop tunnel vision by age 40 and lose central vision by age 60.作者: Delirium 時(shí)間: 2025-3-27 19:07 作者: Little 時(shí)間: 2025-3-27 22:02
Gene Therapy for Mouse Models of ADRP RHO gene. Two strategies for . mRNA silencing have recently been proposed (Millington-Ward et al., 1997; Lewin and Hauswirth, 2001). They are based on the application of therapeutic molecules such as ribozymes (Rz) and small interfering RNA (siRNA) that inhibit . expression.作者: 團(tuán)結(jié) 時(shí)間: 2025-3-28 03:38
Adeno-Associated Viral Vectors and the Retinaral strategies have been attempted to rescue retinal disease, including gene replacement (Acland et al., 2001), gene knockdown with both ribozymes (Gorbatyuk et al., 2007) and siRNA (Kiang et al., 2005), and therapeutic gene supplementation (Deng et al., 2005).作者: Reclaim 時(shí)間: 2025-3-28 08:45
Alexis-Pierre Bemelmans,Corinne Kostic,Maité Cachafeiro,Sylvain V. Crippa,Dana Wanner,Meriem Tekaya,作者: 橫條 時(shí)間: 2025-3-28 14:10 作者: 歌劇等 時(shí)間: 2025-3-28 16:30
Kristina Narfstr? m,Mathias Seeliger,Chooi-May Lai,Vaegan,Martin Katz,Elizabeth P. Rakoczy,Charlotte作者: 混亂生活 時(shí)間: 2025-3-28 20:42 作者: 細(xì)微的差異 時(shí)間: 2025-3-29 02:37 作者: 笨重 時(shí)間: 2025-3-29 05:59 作者: BOOM 時(shí)間: 2025-3-29 08:20
eckt meiner Ansicht nach in dem Nietzsche-Zitat eine Wahrheit, die auch für uns zutreffend ist und die weniger heroisch ausgedrückt lauten k?nnte: ?Wer die Herausforderungen seines Lebens einigerma?en souver?n und unbeschadet bestehen will, darf sich dafür bei aller Ernsthaftigkeit auch einen spiele作者: 從屬 時(shí)間: 2025-3-29 12:31 作者: cutlery 時(shí)間: 2025-3-29 19:11 作者: poliosis 時(shí)間: 2025-3-29 20:01 作者: 獨(dú)輪車 時(shí)間: 2025-3-30 01:12
Yogita Kanan,Anne Kasus Jacobi,Kjell Sawyer,David S. Mannel,Joyce Tombran Tink,Muayyad R. Al-Ubaidieckt meiner Ansicht nach in dem Nietzsche-Zitat eine Wahrheit, die auch für uns zutreffend ist und die weniger heroisch ausgedrückt lauten k?nnte: ?Wer die Herausforderungen seines Lebens einigerma?en souver?n und unbeschadet bestehen will, darf sich dafür bei aller Ernsthaftigkeit auch einen spiele作者: faultfinder 時(shí)間: 2025-3-30 07:25
Yun-Zheng Le,Lixin Zheng,Yuwei Le,Edmund B. Rucker III,Robert E. Andersoneckt meiner Ansicht nach in dem Nietzsche-Zitat eine Wahrheit, die auch für uns zutreffend ist und die weniger heroisch ausgedrückt lauten k?nnte: ?Wer die Herausforderungen seines Lebens einigerma?en souver?n und unbeschadet bestehen will, darf sich dafür bei aller Ernsthaftigkeit auch einen spiele作者: 天氣 時(shí)間: 2025-3-30 10:56
Markus Thiersch,Wolfgang Raffelsberger,Enrico Frigg,Marijana Samardzija,Patricia Blank,Olivier Poch,rsit?ten Basel, Würzburg und Heidelberg Geh. Hofrat ein akademischer Festakt statt, zu dem über 150 deutsche und ausl?ndische Chirurgen sich versammelt hatten. Er wurde im Gartenpavillon, dem alten Theatrum Anatomicum des Julius- spitals abgehalten, einem akademisch traditions reichen Raume. Die Ehrung galt e978-3-642-49608-0978-3-642-49900-5作者: 不可磨滅 時(shí)間: 2025-3-30 16:05 作者: 易碎 時(shí)間: 2025-3-30 17:04 作者: 生氣地 時(shí)間: 2025-3-30 23:34
