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標(biāo)題: Titlebook: Rational Design of Stable Protein Formulations; Theory and Practice John F. Carpenter,Mark C. Manning Book 2002 Springer Science+Business M [打印本頁(yè)]

作者: 貪污    時(shí)間: 2025-3-21 18:04
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作者: 背帶    時(shí)間: 2025-3-21 20:55
Brent S. Kendrick,Tiansheng Li,Byeong S. Changve been shown to be misleading. Current work in neurobiology has demonstrated evidence of discrete neurotransmitter systems having quite specific information processing functions, and central roles in the regulation of behaviour. Even the venerable curvilinear relationship between motivation and per
作者: VOC    時(shí)間: 2025-3-22 01:37
Jeffrey D. Meyer,Bert Ho,Mark C. Manning1) the relative time spent moving versus scanning and (2) the angle of directional change between successive bouts of movement. Both of these vary with visual scope, visibility and other environmental factors in ways that maximize the area scanned, yet minimize overlap of successive areas searched.
作者: aptitude    時(shí)間: 2025-3-22 05:51
John F. Carpenter,Beyong S. Chang,William Garzon-Rodriguez,Theodore W. Randolph1) the relative time spent moving versus scanning and (2) the angle of directional change between successive bouts of movement. Both of these vary with visual scope, visibility and other environmental factors in ways that maximize the area scanned, yet minimize overlap of successive areas searched.
作者: 內(nèi)部    時(shí)間: 2025-3-22 08:50
Geoffrey Leedition, primary or transient creep will be seen as partly a nonrecoverable change of structure and only partly as a damped recoverable change. It seems that the inclusion of structure factors could make the constitutive equations for rocks correspond more closely to the phenomena they attempt to des
作者: excursion    時(shí)間: 2025-3-22 14:40

作者: 婚姻生活    時(shí)間: 2025-3-22 20:04

作者: 溺愛(ài)    時(shí)間: 2025-3-22 23:17
ed to the formulation of the general equation of the energetics of muscular exercise. The general equation was analytically discussed by di Prampero in 1981. That review was the last systematic overview of the energetics of muscular exercise. Several important reviews came afterwards, but only on sp
作者: Duodenitis    時(shí)間: 2025-3-23 04:41
cific information processing functions, and central roles in the regulation of behaviour. Even the venerable curvilinear relationship between motivation and per978-94-010-8479-6978-94-009-4448-0Series ISSN 0258-123X
作者: 烤架    時(shí)間: 2025-3-23 08:33
Tsutomu Arakawa,Tiansheng Li,Linda O. Narhicific information processing functions, and central roles in the regulation of behaviour. Even the venerable curvilinear relationship between motivation and per978-94-010-8479-6978-94-009-4448-0Series ISSN 0258-123X
作者: 積云    時(shí)間: 2025-3-23 12:14

作者: 平躺    時(shí)間: 2025-3-23 16:12

作者: 爭(zhēng)吵加    時(shí)間: 2025-3-23 18:05
High Throughput Formulation: Strategies for Rapid Development of Stable Protein Products,andidates at a much faster rate than was possible during the early years of the biotechnology industry. Couple these changes with the impending publication of the complete sequence of the human genome by 2001 and there is a potential for an additional 15,000 protein drugs from the predicted 150,000
作者: Anterior    時(shí)間: 2025-3-23 22:57

作者: 裝入膠囊    時(shí)間: 2025-3-24 03:50
https://doi.org/10.1007/978-1-4615-0557-0Glycin; Oxidation; Polypeptide; biotechnology; databases; preparation; primary structure; protein; proteins
作者: ARM    時(shí)間: 2025-3-24 08:01

作者: PATHY    時(shí)間: 2025-3-24 11:47
Rational Design of Stable Protein Formulations978-1-4615-0557-0Series ISSN 1078-0467
作者: 吼叫    時(shí)間: 2025-3-24 18:12
Practical Approaches to Protein Formulation Development,lopment of stable protein formulations may require even more resources and effort than conventional small molecule pharmaceuticals. Proteins typically have more stability issues as a result of their complexity and delicate structural stability. Fortunately, a great deal of research regarding protein
作者: fiscal    時(shí)間: 2025-3-24 20:48

作者: BILL    時(shí)間: 2025-3-25 00:04

作者: 責(zé)怪    時(shí)間: 2025-3-25 04:18
Effects of Conformation on the Chemical Stability of Pharmaceutically Relevant Polypeptides,on cannot be ignored. A large number of possible chemical reactions have been identified as leading to decomposition of polypeptides (.). However, a select few are of primary concern to pharmaceutical scientists. In particular, hydrolysis and oxidation reactions appear to be the most common source o
作者: 提名    時(shí)間: 2025-3-25 08:08

作者: largesse    時(shí)間: 2025-3-25 15:40
Spray-Drying of Proteins,y delivery. In addition, fine powders of proteins have application in other delivery systems (e.g., implantable pumps). If the correct formulation and spray-drying conditions can be identified, then a product can be obtained with a high yield and having a large fine-particle dose. Spray-drying is th
作者: CAGE    時(shí)間: 2025-3-25 18:04
Surfactant-Protein Interactions,ly stable, and thus relatively minor perturbing forces can disrupt protein structure, causing loss of biological activity, as well as formation of non-native protein aggregates. Such perturbations are commonly encountered as proteins are produced, stored, transported, and delivered to patients. For
作者: 挑剔為人    時(shí)間: 2025-3-25 23:21

作者: FADE    時(shí)間: 2025-3-26 02:54

作者: Insensate    時(shí)間: 2025-3-26 06:07
1078-0467 formulation of protein pharmaceuticals from a much more rational point of view...This book describes the current level of understanding of protein instability and the strategies for stabilizing proteins under a variety of stressful conditions. .978-1-4613-5131-3978-1-4615-0557-0Series ISSN 1078-0467
作者: 信條    時(shí)間: 2025-3-26 12:33

作者: Guileless    時(shí)間: 2025-3-26 15:43

作者: Flat-Feet    時(shí)間: 2025-3-26 18:51
Surfactant-Protein Interactions,ilization (.; .), nebulization (.) and spray-drying (.; .; .; .; .; .) proteins can suffer damage to their native conformation. Further, delivery of protein pharmaceuticals to patients may also provoke losses of conformational integrity via unfavorable interactions of proteins with surfaces (e.g., inner walls of catheter tubing or syringes (.)).
作者: DAMN    時(shí)間: 2025-3-26 21:22
Book 2002r the past few years, our fundamental understanding of how proteins degrade and how stabilizing agents work has made it possible to approach formulation of protein pharmaceuticals from a much more rational point of view...This book describes the current level of understanding of protein instability
作者: Deceit    時(shí)間: 2025-3-27 04:03

作者: Living-Will    時(shí)間: 2025-3-27 08:58

作者: 澄清    時(shí)間: 2025-3-27 12:02
Physical Stabilization of Proteins in Aqueous Solution,at-urations are often accompanied by covalent and non-covalent aggregates that not only can destroy the activity of the drug, but also cause adverse side effects (.; .). Without the ability to stabilize native protein structures, even the most efficacious protein therapeutics will fail to make viable drug products.
作者: lanugo    時(shí)間: 2025-3-27 14:08

作者: Coronation    時(shí)間: 2025-3-27 17:47

作者: labile    時(shí)間: 2025-3-27 22:12
Tsutomu Arakawa,Tiansheng Li,Linda O. Narhiatement of one of the classic problems of psychology - that of acc- ounting for motivational or intensive aspects of behaviour, as opposed to structural or directional aspects. The term "energetics" was first used in the 1930‘s by Freeman, Duffy and others, following Cannon‘s energy mobilization vie
作者: 善辯    時(shí)間: 2025-3-28 05:31

作者: 大方不好    時(shí)間: 2025-3-28 10:03
Jeffrey D. Meyer,Bert Ho,Mark C. Manningtary techniques variously have been termed ambush or sit-and-wait strategies; more mobile ones have been called cruise searching, widely ranging searching, active foraging or simply foraging. Some species may employ either type, depending on circumstances (Muma 1966; Cloudsley-Thompson 1991). Interm
作者: 太空    時(shí)間: 2025-3-28 12:24





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