標(biāo)題: Titlebook: RNA Technologies in Cardiovascular Medicine and Research; Volker A. Erdmann,Wolfgang Poller,Jan Barciszewski Book 2008 Springer-Verlag Ber [打印本頁(yè)] 作者: 不能平庸 時(shí)間: 2025-3-21 16:19
書(shū)目名稱(chēng)RNA Technologies in Cardiovascular Medicine and Research影響因子(影響力)
書(shū)目名稱(chēng)RNA Technologies in Cardiovascular Medicine and Research影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)RNA Technologies in Cardiovascular Medicine and Research網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱(chēng)RNA Technologies in Cardiovascular Medicine and Research網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱(chēng)RNA Technologies in Cardiovascular Medicine and Research被引頻次
書(shū)目名稱(chēng)RNA Technologies in Cardiovascular Medicine and Research被引頻次學(xué)科排名
書(shū)目名稱(chēng)RNA Technologies in Cardiovascular Medicine and Research年度引用
書(shū)目名稱(chēng)RNA Technologies in Cardiovascular Medicine and Research年度引用學(xué)科排名
書(shū)目名稱(chēng)RNA Technologies in Cardiovascular Medicine and Research讀者反饋
書(shū)目名稱(chēng)RNA Technologies in Cardiovascular Medicine and Research讀者反饋學(xué)科排名
作者: 飲料 時(shí)間: 2025-3-21 20:28 作者: amphibian 時(shí)間: 2025-3-22 01:16
Targeting Viral Heart Disease by RNA Interference successfully targeted by RNA interference, thus leading to increased cell viability and even prolongation of survival in vivo. However, considerable limitations have to be solved before this novel therapeutic approach may enter the clinical trials arena.作者: 戲服 時(shí)間: 2025-3-22 08:38 作者: 同謀 時(shí)間: 2025-3-22 09:22 作者: infarct 時(shí)間: 2025-3-22 14:35 作者: Exclaim 時(shí)間: 2025-3-22 20:53 作者: 蘆筍 時(shí)間: 2025-3-23 00:21 作者: ICLE 時(shí)間: 2025-3-23 01:39
Noncoding RNAs in Human Diseasesading frames translated into proteins. There is a growing number of genes which yield noncoding RNAs (ncRNA) playing multiple functions in regulation of gene expression. Many of the ncRNAs have been shown to be associated with certain human diseases including neurobehavioral, developmental disorders and cancer.作者: Adj異類(lèi)的 時(shí)間: 2025-3-23 09:28 作者: 神圣在玷污 時(shí)間: 2025-3-23 10:28 作者: Explosive 時(shí)間: 2025-3-23 15:13
miRNAs and Their Emerging Role in Cardiac Hypertrophyf targeted messenger RNAs (mRNAs). More than one-third of human protein-coding mRNAs are predicted as being regulated by miRNAs, which have been implicated in processes as diverse as cancer and muscle biology. Now, recent studies demonstrate that the expression profiles of many miRNAs change during 作者: Expostulate 時(shí)間: 2025-3-23 18:49
MicroRNAs and the Control of Heart Pathophysiologynt class of gene regulatory molecules in multicellular organisms, and are being implicated in an increasing number of biological processes. Many miRNAs are expressed in a tissue-specific manner during development and take part in the regulation of cell-lineage decisions and morphogenesis. Moreover, 作者: 蚊帳 時(shí)間: 2025-3-24 00:40
MicroRNA Systems Biologytrast, RNAs have been thought as molecules which are only transferring genetic information for protein production. Recently, microRNAs (miRNAs) have emerged as another layer of gene regulation. They regulate many key biological processes, including cell growth, death, development and differentiation作者: Lethargic 時(shí)間: 2025-3-24 05:09
Targeting Viral Heart Disease by RNA Interferenced an important cause for VHD in both populations. VHD may lead to dilated cardiomyopathy and heart failure which can ultimately require heart transplantation. However, no specific treatment modality is so far available. We and others have shown that coxsackieviral replication and cytotoxicity can be作者: Arthritis 時(shí)間: 2025-3-24 09:05 作者: 改變立場(chǎng) 時(shí)間: 2025-3-24 11:18 作者: 奇思怪想 時(shí)間: 2025-3-24 15:23
Cardiac Delivery of Nucleic Acids by Transcriptional and Transductional Targeting of Adeno-Associateficiency of cardiac transfer. Efficient and sustained cardiac delivery in large animal models and finally clinical trials requires transfer of vectorized shRNA with suitable application systems. Packaging shRNA constructs in targeted adeno-associated viral (AAV) vectors may be versatile for systemic作者: 激勵(lì) 時(shí)間: 2025-3-24 23:05
Characterization of Hammerhead Ribozymes Potentially Suitable for the Treatment of Hyper-Proliferatirhead ribozymes were the first type of nucleic acid based drugs to be extensively studied and predicted to be of potential practical utility. These are catalytic RNA molecules capable of inducing the site-specific cleavage of a phosphodiester bond within an RNA molecule. Thus, they can be used to re作者: DALLY 時(shí)間: 2025-3-24 23:30 作者: 觀點(diǎn) 時(shí)間: 2025-3-25 04:09
Noncoding RNAs in Human Diseasession of genetic information. Discoveries of new classes of RNA without protein coding potential and large scale cDNA sequencing projects demonstrated that, contrary to the original view, the cellular functions and the processes associated with growth and development of organisms do not depend solely作者: 外表讀作 時(shí)間: 2025-3-25 07:29 作者: TATE 時(shí)間: 2025-3-25 14:27
Nucleic Acid Aptamers for Cardiovascular Therapeuticsin target with high specificity and affinity. Aptamers can be generated in a controlled and entirely in vitro process known as SELEX. Advances in aptamer technology have made possible the application of this therapeutic modality to many therapeutic areas including cardiovascular indications. To that作者: REP 時(shí)間: 2025-3-25 16:08
NFκB Decoy Oligodeoxynucleotide-Based Therapy in Cardiovascular Diseasesthe regulation of powerful transcriptional factors which could be mainly involved in the process of atherosclerosis, myocardial infarction, and vascular remodeling, etc. The transcription factor nuclear factor-kappa B (NF-κB) plays a pivotal role in the coordinated transactivation of cytokine and ad作者: SEEK 時(shí)間: 2025-3-25 20:47
Antisense Therapy for Restenosis Following Percutaneous Coronary Interventionsg responses that can lead to vessel obstruction or restenosis following injury..Recent studies have focused on the use of antisense compounds to prevent recurrent vessel obstruction or restenosis following PTCA. Some antisense compounds can inhibit the cell cycle response to injury in the G-1 by blo作者: 即席 時(shí)間: 2025-3-26 02:38
Toxic RNA in Pathogenesis of Human Neuromuscular Disordersof these diseases, such as myotonic dystrophy, fragile X-associated tremor/ataxia syndrome, spinocerebellar ataxias 8, 10, 12 and Huntington’s disease-like 2, are caused by an increased number of tri-, tetra- or pentanucleotide repeats in noncoding regions of the mutated genes. An RNA gain-of-functi作者: Relinquish 時(shí)間: 2025-3-26 04:32 作者: 種類(lèi) 時(shí)間: 2025-3-26 09:08 作者: 紳士 時(shí)間: 2025-3-26 13:49
RNA Technologies in Cardiovascular Medicine and Research978-3-540-78709-9作者: GRIPE 時(shí)間: 2025-3-26 20:21 作者: Lumbar-Stenosis 時(shí)間: 2025-3-26 23:50 作者: heckle 時(shí)間: 2025-3-27 02:14 作者: 佛刊 時(shí)間: 2025-3-27 08:26
Design of siRNAs and shRNAs for RNA Interference: Possible Clinical Applications(U6, H1, 7SK), which were in cells processed into active siRNAs..In parallel with the study of RNAi, progress in understanding the cellular processing and function of microRNAs (miRNAs) was achieved. RNAi and miRNA systems share most if not all components of the silencing pathway. A direct consequen作者: 小卒 時(shí)間: 2025-3-27 12:23 作者: MENT 時(shí)間: 2025-3-27 13:59 作者: 敵意 時(shí)間: 2025-3-27 20:36 作者: Vasoconstrictor 時(shí)間: 2025-3-27 23:59 作者: 感染 時(shí)間: 2025-3-28 05:49 作者: Ambulatory 時(shí)間: 2025-3-28 09:36
T. E. Callis,M. Tatsuguchi,D. Z. Wangch and describes advanced analytical tools. Both basic and clinical investigators in this field should find the reviews and interpretations provided clear and informative. Clinicians will find this volume easy to assimilate. While direct clinical applications may be down the road, the insights provi作者: 防銹 時(shí)間: 2025-3-28 14:26
D. Catalucci,M. V. G. Latronico,G. Condorelli this subgroup. Finally, a slow individual alpha peak frequency is an endophenotype associated with treatment resistance in ADHD and depression. Future studies should incorporate this endophenotype in clinical trials to investigate further the efficacy of new treatments in this substantial subgroup 作者: 得意牛 時(shí)間: 2025-3-28 17:58 作者: 跳動(dòng) 時(shí)間: 2025-3-28 18:56
S. Merl,R. Wesselythe flow of ions and molecules in the resting state. Combined with structural data, electrophysiological studies have allowed the discovery of structure-function relationships that shed light on functional mechanisms. In some cases, the channel properties have been investigated in the presence of na作者: Ligament 時(shí)間: 2025-3-29 00:25
V. Pekarikg by electrical field, medium pH, and membrane lipid composition. The second part of this review addresses the novel mechanism of VDAC regulation by dimeric tubulin, an abundant cytosolic protein, and the physiological implications of the uncovered VDAC-tubulin interaction. One of the intriguing con作者: ARK 時(shí)間: 2025-3-29 06:39
W. Poller,L. Suckau,S. Pinkert,H. Fechnerthe flow of ions and molecules in the resting state. Combined with structural data, electrophysiological studies have allowed the discovery of structure-function relationships that shed light on functional mechanisms. In some cases, the channel properties have been investigated in the presence of na作者: BRINK 時(shí)間: 2025-3-29 08:15
O. J. Müller,H. A. Katusf these non-enzymatic staphylococcal β-PFTs is the homoheptameric α-hemolysin (αHL) protein. Moreover, . has the ability to secrete up to four heteromeric, bi-component β-PFTs. Although the homomeric and heteromeric β-PFTs are related in sequence, homology, and structure, they demonstrate distinct b作者: 蒸發(fā) 時(shí)間: 2025-3-29 13:21 作者: cochlea 時(shí)間: 2025-3-29 18:21
E. -H. Yao,N. Fukudag by electrical field, medium pH, and membrane lipid composition. The second part of this review addresses the novel mechanism of VDAC regulation by dimeric tubulin, an abundant cytosolic protein, and the physiological implications of the uncovered VDAC-tubulin interaction. One of the intriguing con作者: osculate 時(shí)間: 2025-3-29 21:17
M. Szymański,J. Barciszewskinuous activity in neuronal firing patterns related complexly and in stochastic ways to sensory stimuli; and of brain substance organized in a series of tissue compartments, each contributing functionally to the whole, and carrying with them the keys to that most unique function of brain tissue, the 作者: 原告 時(shí)間: 2025-3-30 03:22
C. M. Blake,S. Oney,S. M. Nimjee,B. A. Sullenger progenitors and neurons in ferrets. Furthermore, multiple genes can be efficiently co-expressed in the same progenitors and neurons. Our method promises to be a powerful tool for investigating the mechanisms underlying the development, function, and pathophysiology of neuronal structures that are u作者: 縮影 時(shí)間: 2025-3-30 05:45 作者: Accord 時(shí)間: 2025-3-30 10:48
H. Nakagami,M. K. Osako,N. Tomita,R. Morishitahe large range of new specialized electrodes, developed also in the frame of the other electroporation-based treatments (electrochemotherapy). Indeed, electric pulses are now routinely applied for localized drug delivery in the treatment of solid tumors by electrochemotherapy. The mechanisms involve作者: 制定法律 時(shí)間: 2025-3-30 12:50
N. Kipshidzeerent sites. The addition of AuNPs during electroporation therefore benefits not only quicker recovery and better survival of cells but also more efficient uptake of the subjected probes. Such enhancement was successfully confirmed on a chronic myeloid leukemia cell line (i.e., K562 cells) in both a作者: FLEET 時(shí)間: 2025-3-30 17:15
D. Napierala,M. Napieralaroper setting of the electrical parameters and pulsing buffers. EP can be easily directly applied on animals. Preclinical studies showed that electropermeabilization brings a direct cytoplasmic distribution of siRNA and an efficient silencing of the targeted protein expression. EP appears as a promi作者: 條約 時(shí)間: 2025-3-30 23:36
he large range of new specialized electrodes, developed also in the frame of the other electroporation-based treatments (electrochemotherapy). Indeed, electric pulses are now routinely applied for localized drug delivery in the treatment of solid tumors by electrochemotherapy. The mechanisms involve作者: 縮短 時(shí)間: 2025-3-31 01:06
T. E. Callis,M. Tatsuguchi,D. Z. Wanghas in fact shed much light on some of the neural processes contributing to the development of psychiatric symptoms and/or their amelioration following treatment. In the first part of this volume, we have selected a number of conditions where psychophysiological investigations have recently provided作者: 輕而薄 時(shí)間: 2025-3-31 07:16 作者: 射手座 時(shí)間: 2025-3-31 10:58
E. Wangnel is responsible for most of the metabolite flux in and out of mitochondria. Small ions, adenine nucleotides such as ATP and ADP, and other water soluble mitochondrial respiratory substrates cross the MOM through VDAC. Therefore, any restriction to metabolite exchange through VDAC is able to lead 作者: cuticle 時(shí)間: 2025-3-31 14:12 作者: 灰姑娘 時(shí)間: 2025-3-31 18:09 作者: 斷斷續(xù)續(xù) 時(shí)間: 2025-4-1 00:26
W. Poller,L. Suckau,S. Pinkert,H. Fechnerria, they often constitute one of the components of molecular machines that participate in membrane biogenesis, assembly of surface exposed appendages, and the secretion of protein substrates across the cell envelope. Their pore-forming properties make them directly amenable to electrophysiology, ev作者: 古老 時(shí)間: 2025-4-1 03:36
