標(biāo)題: Titlebook: RNA Interference and CRISPR Technologies; Technical Advances a Mouldy Sioud Book 2020 Springer Science+Business Media, LLC, part of Springe [打印本頁] 作者: 轉(zhuǎn)變 時(shí)間: 2025-3-21 17:14
書目名稱RNA Interference and CRISPR Technologies影響因子(影響力)
書目名稱RNA Interference and CRISPR Technologies影響因子(影響力)學(xué)科排名
書目名稱RNA Interference and CRISPR Technologies網(wǎng)絡(luò)公開度
書目名稱RNA Interference and CRISPR Technologies網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱RNA Interference and CRISPR Technologies被引頻次
書目名稱RNA Interference and CRISPR Technologies被引頻次學(xué)科排名
書目名稱RNA Interference and CRISPR Technologies年度引用
書目名稱RNA Interference and CRISPR Technologies年度引用學(xué)科排名
書目名稱RNA Interference and CRISPR Technologies讀者反饋
書目名稱RNA Interference and CRISPR Technologies讀者反饋學(xué)科排名
作者: Incise 時(shí)間: 2025-3-22 00:17
Chemical Modifications in RNA Interference and CRISPR/Cas Genome Editing Reagents,e. Relevant chemical modifications also include conjugated targeting ligands to assist ON delivery to specific cell types. Chemical modifications are most beneficial for therapeutically relevant ONs, as they serve to enhance target binding, increase drug longevity, facilitate cell-specific targeting作者: Diverticulitis 時(shí)間: 2025-3-22 01:43 作者: QUAIL 時(shí)間: 2025-3-22 05:50
Cancer Immunotherapy: Targeting Tumor-Associated Macrophages by Gene Silencing,ology and current strategies for the targeting of TAMs using small interfering RNA (siRNA)-based drugs. In the past few years, advances in the field of nanomedicine pave the way for the development of siRNA-based drugs as an additional class of personalized cancer immuno-nanomedicines. Fundamental c作者: creatine-kinase 時(shí)間: 2025-3-22 11:34
Book 2020 resource for any scientist, teachers, graduate student, postdoc,and clinician interested in this field. This book also benefits anyone in research and development in biotech and pharmaceutical companies who want to understand more about these technologies, and their applications in biology and medi作者: 窒息 時(shí)間: 2025-3-22 13:39
he need for future research on digitalized co-production with an explicit focus on the ICT artifact and its co-creation artifact as catalysts for change. In relation to this, this study confirms previous research arguing for the merging of policy science and information systems research in an era of作者: corpuscle 時(shí)間: 2025-3-22 20:28
Mouldy Sioud to consider different approaches based on citizens’ roles when organizing open data hackathons. This paper contributes to the literature by providing insight in the motivations of citizens engaging in open agriculture data hackathons in comparison with hackathons in other sectors, and by mapping ci作者: 門窗的側(cè)柱 時(shí)間: 2025-3-23 01:14
Kim A. Lennox,Mark A. Behlke can explain the adoption of certain social media platforms. The results show that, indeed, demographic characteristics and administrative capacity are important factors for the adoption of less popular social media. Surprisingly, we also observe a geographical difference in municipalities’ social m作者: critic 時(shí)間: 2025-3-23 02:33 作者: 密碼 時(shí)間: 2025-3-23 07:08
Seung Koo Lee,Benedict Law,Ching-Hsuan Tung to consider different approaches based on citizens’ roles when organizing open data hackathons. This paper contributes to the literature by providing insight in the motivations of citizens engaging in open agriculture data hackathons in comparison with hackathons in other sectors, and by mapping ci作者: monogamy 時(shí)間: 2025-3-23 11:27 作者: Epithelium 時(shí)間: 2025-3-23 16:41 作者: 魅力 時(shí)間: 2025-3-23 18:02 作者: 有毒 時(shí)間: 2025-3-23 22:26
Lijia Yu,Duanwei Liang,Nannan Jing,Changmai Chen,Xinjing Tang, content-generation and the development of loosely-coupled communities. They provide the forum for much discussion and interaction. In this respect social networking could contribute to solve some of the problems of engaging their users that eParticipation services often struggle with. This paper i作者: 溫和女人 時(shí)間: 2025-3-24 05:00 作者: Biguanides 時(shí)間: 2025-3-24 09:20
Njabulo Mnyandu,Patrick Arbuthnot,Mohube Betty Maepascript. We also developed a prototype debate support system called citispe@k that uses SOCIA to help citizens share their concerns. Users can submit agendas, ideas, questions, and answers by referencing the structured regional information in SOCIA. Moreover, they can annotate SOCIA data with tags re作者: osteopath 時(shí)間: 2025-3-24 13:29 作者: Fester 時(shí)間: 2025-3-24 18:26
Shi-Lung Lin,Jack S. Chen,Shao-Yao Yingvic issues and concerns. In this paper we report findings from a 2012 survey of residents in the geographic community of Blacksburg, Virginia and environs. The main implication of our findings is that social media use for civic purposes is less strongly associated with and predicted by education and作者: 角斗士 時(shí)間: 2025-3-24 22:40
Jaroslav Juracek,Ondrej Slabyl City Authority use to disclose information on its operations? What is the mix of offline- and online channels (blended participation) do local political representatives use to connect with electorates? Is this more for planning or for monitoring purposes. To answer these questions, both quantitati作者: 漂亮才會(huì)豪華 時(shí)間: 2025-3-24 23:44 作者: 去才蔑視 時(shí)間: 2025-3-25 05:34 作者: 支柱 時(shí)間: 2025-3-25 11:22 作者: 警告 時(shí)間: 2025-3-25 13:41
Karin Zins,Dietmar Abrahaml City Authority use to disclose information on its operations? What is the mix of offline- and online channels (blended participation) do local political representatives use to connect with electorates? Is this more for planning or for monitoring purposes. To answer these questions, both quantitati作者: COST 時(shí)間: 2025-3-25 16:31
Nicholas Paul Casey,Jon Amund Kyte,Hiroshi Fujiwaral City Authority use to disclose information on its operations? What is the mix of offline- and online channels (blended participation) do local political representatives use to connect with electorates? Is this more for planning or for monitoring purposes. To answer these questions, both quantitati作者: 忍耐 時(shí)間: 2025-3-25 22:05 作者: 金桌活畫面 時(shí)間: 2025-3-26 00:26 作者: ULCER 時(shí)間: 2025-3-26 04:47
978-1-0716-0292-8Springer Science+Business Media, LLC, part of Springer Nature 2020作者: 大包裹 時(shí)間: 2025-3-26 11:27 作者: 痛得哭了 時(shí)間: 2025-3-26 14:03 作者: 時(shí)間等 時(shí)間: 2025-3-26 17:49 作者: 驕傲 時(shí)間: 2025-3-26 23:43 作者: Torrid 時(shí)間: 2025-3-27 01:31 作者: 賠償 時(shí)間: 2025-3-27 09:22 作者: JECT 時(shí)間: 2025-3-27 10:25
Kim A. Lennox,Mark A. Behlkeg the 308 municipalities in Portugal. Extending previous analyses of Facebook and/or Twitter usage levels, we examine why local governments adopt a particular social media platform. More concretely, we explore, with statistical analyses, the determinants of the adoption of different types of social 作者: BALE 時(shí)間: 2025-3-27 16:25
Ivan V. Chernikov,Mariya I. Meschaninova,Elena L. Chernolovskayay. Participatory budgeting (PB), in particular, is generally rooted in online platforms, but as our case study on the City of Helsinki PB trial suggests, face-to-face events are necessary to engage targeted and often less resourceful actors in the process. Based on a longer-term participant observat作者: 搜尋 時(shí)間: 2025-3-27 20:35
Seung Koo Lee,Benedict Law,Ching-Hsuan Tungplore the motivations of citizens who engage in open agriculture data hackathons. We conducted a case study and analyzed data collected from 161 participants of 11 farming hackathons held between 2016 and 2018 in the Netherlands. We found that participants of open agriculture data hackathons have di作者: LUT 時(shí)間: 2025-3-27 22:39
Shiva Kheiriabad,Maryam Ghaffari,Jafar Ezzati Nazhad Dolatabadi,Michael R. Hamblincitizens as users of said services. This paper sets out to explore the possible variations in which the citizen as a user of digital public services is conceptualized within the e-government literature. Through a qualitative and interpretive approach, we have analysed literature from different field作者: habile 時(shí)間: 2025-3-28 05:57 作者: sacrum 時(shí)間: 2025-3-28 09:21 作者: 確認(rèn) 時(shí)間: 2025-3-28 12:38
Lijia Yu,Duanwei Liang,Nannan Jing,Changmai Chen,Xinjing Tang-services are provided for them. Most forms of eParticipation in democratic contexts are, however, dependent on citizen engagement, interaction and social networking because democratic systems favour the interests of larger groups of citizens – the more voices behind a political proposition, the gre作者: Femine 時(shí)間: 2025-3-28 17:31 作者: faultfinder 時(shí)間: 2025-3-28 20:09
Njabulo Mnyandu,Patrick Arbuthnot,Mohube Betty Maepablic participation, we aim to utilize web contents related to target regions for sharing public concerns among citizens, government officials, and experts. We have designed a Linked Open Data set called SOCIA (Social Opinions and Concerns for Ideal Argumentation) to structure regional web contents (作者: 較早 時(shí)間: 2025-3-29 02:13
Fiona T. van den Berg,Abdullah Ely,Patrick Arbuthnotnformed choices in their personal lives as citizens, and to contribute to policy drafting as an instrument to strengthen the quality of decision-makers’ actions. Although a growing body of literature has been devoted to the main benefits and opportunities that ICT can offer in e-participation, littl作者: keloid 時(shí)間: 2025-3-29 05:07
Shi-Lung Lin,Jack S. Chen,Shao-Yao Ying) contexts in the US. Prior research suggests that the same ’more educated, extroverted, and activist’ type of individuals (i.e., similar to opinion leaders) continued to be more engaged in civic affairs regardless of offline or online context. That is, the advent of Internet access and use did not 作者: neutral-posture 時(shí)間: 2025-3-29 08:52
Jaroslav Juracek,Ondrej Slabys of participation. In other words, a mix of methods is utilised to complement representative participation and city administration. In Uganda, a number of local political representatives: Councilors, Lower level Mayors and Lord Mayor use online participatory instruments; social media platforms: Fac作者: cruise 時(shí)間: 2025-3-29 13:11 作者: 條約 時(shí)間: 2025-3-29 18:01 作者: bisphosphonate 時(shí)間: 2025-3-29 20:07 作者: ciliary-body 時(shí)間: 2025-3-30 02:03 作者: meritorious 時(shí)間: 2025-3-30 04:09 作者: 面包屑 時(shí)間: 2025-3-30 11:13
Kasidet Hiranniramol,Yuhao Chen,Xiaowei Wangs of participation. In other words, a mix of methods is utilised to complement representative participation and city administration. In Uganda, a number of local political representatives: Councilors, Lower level Mayors and Lord Mayor use online participatory instruments; social media platforms: Fac作者: Jejune 時(shí)間: 2025-3-30 15:58
Book 2020tions, design, chemical modifications, delivery, and preclinical/clinical applications. In addition to relevant backgrounds, the chapters in this book discuss simple and accurate protocols dealing with the latest advances in RNAi and CRISPR applications and look at how these methods differ from one 作者: Malleable 時(shí)間: 2025-3-30 19:00 作者: floodgate 時(shí)間: 2025-3-30 22:28 作者: 愛好 時(shí)間: 2025-3-31 02:04 作者: Gullible 時(shí)間: 2025-3-31 07:35 作者: Extricate 時(shí)間: 2025-3-31 13:06
Generating DNA Expression Cassettes Encoding Multimeric Artificial MicroRNA Precursors, protocol. Basic gene silencing function of pri-miRNA mimics in cell culture can then be assessed using a dual luciferase assay and appropriate minimal targets. The methods described here for the generation of effective pri-miRNA mimics targeting HBV can be applied in the silencing of other viral or endogenous genes.作者: PANIC 時(shí)間: 2025-3-31 13:45 作者: Prologue 時(shí)間: 2025-3-31 18:39 作者: 使人煩燥 時(shí)間: 2025-3-31 21:45 作者: Delectable 時(shí)間: 2025-4-1 02:12 作者: abolish 時(shí)間: 2025-4-1 07:34
Chemical Modifications in RNA Interference and CRISPR/Cas Genome Editing Reagents, as continual efforts are being made to optimize ON efficacy. Over the years, RNA interference (RNAi) has become one of the main tools used to inhibit RNA expression across a wide variety of species. Efforts have been made to improve the exogenous delivery of the double-stranded RNA components to th作者: allergy 時(shí)間: 2025-4-1 12:00
Preparation, Determination of Activity, and Biodistribution of Cholesterol-Containing Nuclease-Resiw molecular weight drugs. Despite significant progress in this area, the potential for therapeutic use of RNAi in humans is limited due to the lack of efficient delivery systems. Bioconjugation is one of the most promising methods for delivering siRNA to cells and tissues, since conjugation of siRNA作者: Forsake 時(shí)間: 2025-4-1 16:09
Multifunctional Nanodelivery Platform for Maximizing Nucleic Acids Combination Therapy,rating with other therapeutics; however, transporting siRNA and other active ingredients to the same location at the same time is challenging. Here, we report a novel multifunctional nanodelivery platform by sequentially layering several functional ingredients, such as siRNAs, microRNAs, peptides, a作者: 骨 時(shí)間: 2025-4-1 20:55 作者: CANDY 時(shí)間: 2025-4-1 23:06
Delivery of Functional Small RNAs via Extracellular Vesicles In Vitro and In Vivo,EVs have recently gained significant interest as a promising material for delivery of therapeutics. Small RNAs, including small interfering RNA (siRNA) and microRNA (miRNA), provide a great therapeutic strategy for treating human diseases. However, it remains a challenge to deliver unconjugated smal作者: JAUNT 時(shí)間: 2025-4-2 04:13
