標(biāo)題: Titlebook: RNA Interference; Challenges and Thera Mouldy Sioud Book 2015 Springer Science+Business Media New York 2015 Cancer research.Extracellular m [打印本頁] 作者: Sentry 時(shí)間: 2025-3-21 16:59
書目名稱RNA Interference影響因子(影響力)
書目名稱RNA Interference影響因子(影響力)學(xué)科排名
書目名稱RNA Interference網(wǎng)絡(luò)公開度
書目名稱RNA Interference網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱RNA Interference被引頻次
書目名稱RNA Interference被引頻次學(xué)科排名
書目名稱RNA Interference年度引用
書目名稱RNA Interference年度引用學(xué)科排名
書目名稱RNA Interference讀者反饋
書目名稱RNA Interference讀者反饋學(xué)科排名
作者: OGLE 時(shí)間: 2025-3-21 23:44
Mouldy Sioudf accuracy. The Delphi method, in particular, has been critized, rightly in my view, for merely amplifying the prejudices and wish-fulfillment of a narrow group of experts. But trying to make long term forecasts of the likely development of transmission technologies and their impact upon the media i作者: 幼稚 時(shí)間: 2025-3-22 00:51
Yuko Nakashima,Naoko Abe,Yoshihiro Ito,Hiroshi Abef accuracy. The Delphi method, in particular, has been critized, rightly in my view, for merely amplifying the prejudices and wish-fulfillment of a narrow group of experts. But trying to make long term forecasts of the likely development of transmission technologies and their impact upon the media i作者: 惡臭 時(shí)間: 2025-3-22 05:27 作者: antidote 時(shí)間: 2025-3-22 12:17
Giuseppe De Rosa Ph.D.,Giuseppina Salzanoe wants a material with as low a coercivity as possible, so that hysteresis losses are minimized, or writing times are reduced, such as in transformers, inductors or recording media (though there are special requirements here). Having shown that the source of coercivity is aniso-tropy in magnetic pr作者: IOTA 時(shí)間: 2025-3-22 15:38 作者: Anal-Canal 時(shí)間: 2025-3-22 19:08 作者: CRAFT 時(shí)間: 2025-3-22 21:52
Omar Ahmed,Andrea Krühn,Hermann Lageture of matter at the atomic level. The direct outcome of this understanding is the ability to design and fabricate new materials whose properties are tailored to a given device ap- plication. Although applications of materials science can range from low weight, high strength composites for the auto作者: Desert 時(shí)間: 2025-3-23 03:26 作者: 執(zhí) 時(shí)間: 2025-3-23 08:34
Karin Zins,Mouldy Sioud,Seyedhossein Aharinejad,Trevor Lucas,Dietmar Abrahamin recent years a large part of the research on the theory of condensed matter [5.1,2] has been concentrated in areas formerly considered the domain of materials science. This trend has been aided by the development of methods capable of addressing problems related to the properties of real material作者: 津貼 時(shí)間: 2025-3-23 12:41
Magdolna G. Sebestyén,So C. Wong,Vladimir Trubetskoy,David L. Lewis,Christine I. Wooddellject of this book, is the measurement of electronic quantities like voltage, current, resistance, inductance, and capacitance, to name a few.This book provides practical information concerning the techniques in electronic measurements and knowledge on how to use the electronic measuring instruments 作者: ostrish 時(shí)間: 2025-3-23 15:44
William H. Thiel,Kristina W. Thiel,Katie S. Flenker,Tom Bair,Adam J. Dupuy,James O. McNamara II,Franis book, is the measurement of electronic quantities like voltage, current, resistance, inductance, and capacitance, to name a few.This book provides practical information concerning the techniques in electronic measurements and knowledge on how to use the electronic measuring instruments appropriat作者: Oratory 時(shí)間: 2025-3-23 18:20 作者: URN 時(shí)間: 2025-3-24 01:38
Maximilian C. R. Buff,Stefan Bernhardt,Musa D. Marimani,Abdullah Ely,Joachim W. Engels,Patrick Arbutis book, is the measurement of electronic quantities like voltage, current, resistance, inductance, and capacitance, to name a few.This book provides practical information concerning the techniques in electronic measurements and knowledge on how to use the electronic measuring instruments appropriat作者: inventory 時(shí)間: 2025-3-24 04:24 作者: Confidential 時(shí)間: 2025-3-24 08:31
Per Ole Iversen,Mouldy Sioudject of this book, is the measurement of electronic quantities like voltage, current, resistance, inductance, and capacitance, to name a few.This book provides practical information concerning the techniques in electronic measurements and knowledge on how to use the electronic measuring instruments 作者: ADORN 時(shí)間: 2025-3-24 13:25
Mouldy Sioud,Anne Mobergslien,Stein S?b?e-Larssenject of this book, is the measurement of electronic quantities like voltage, current, resistance, inductance, and capacitance, to name a few.This book provides practical information concerning the techniques in electronic measurements and knowledge on how to use the electronic measuring instruments 作者: 密切關(guān)系 時(shí)間: 2025-3-24 15:38
Michael Koldehoff M.D., Ph.D.ient care, to provide the data needed for more effective population management and quality assurance of both an individual practice’s patients and well as patients of large health care systems, and the potential to create efficiencies that allow physicians to provide this improved care at a far lowe作者: 承認(rèn) 時(shí)間: 2025-3-24 19:01
Anne Mobergslien,Mouldy Sioudre setting.Offers invaluable insights from other primary carPhysician adoption of electronic medical records (EMRs) has become a national priority. It is said that EMRs have the potential to greatly improve patient care, to provide the data needed for more effective population management and quality作者: Biofeedback 時(shí)間: 2025-3-25 02:36 作者: 銀版照相 時(shí)間: 2025-3-25 04:31 作者: 解開 時(shí)間: 2025-3-25 09:57 作者: accordance 時(shí)間: 2025-3-25 13:20
Methods in Molecular Biologyhttp://image.papertrans.cn/r/image/820166.jpg作者: 冒煙 時(shí)間: 2025-3-25 17:19
https://doi.org/10.1007/978-1-4939-1538-5Cancer research; Extracellular miRNAs; Off-target effects; RNAi gene silencing; Small RNA transcriptomes作者: FOLD 時(shí)間: 2025-3-25 20:20
Nanostructured RNAs for RNA Interference,d RNAs. All three nanostructured RNAs were transformed into double-stranded RNA of approximately 20 base pairs when they were treated with nuclease enzymes such as Dicer. These dsRNA species induced gene silencing when they are were introduced into mammalian cells.作者: Galactogogue 時(shí)間: 2025-3-26 01:37
Mouldy SioudIncludes cutting-edge techniques in using RNA interference for therapeutic purposes.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from th作者: 昏迷狀態(tài) 時(shí)間: 2025-3-26 07:16 作者: Immobilize 時(shí)間: 2025-3-26 08:29 作者: cluster 時(shí)間: 2025-3-26 12:53 作者: 做方舟 時(shí)間: 2025-3-26 17:22 作者: GRUEL 時(shí)間: 2025-3-26 21:40
Overcoming the Challenges of siRNA Activation of Innate Immunity: Design Better Therapeutic siRNAs, siRNAs in functional genomics and human therapies depends on the development of strategies to overcome siRNA unwanted effects. This chapter highlights some efficient strategies aimed at separating gene silencing from immunostimulation and improving siRNA gene silencing specificity.作者: Intervention 時(shí)間: 2025-3-27 01:45 作者: 前奏曲 時(shí)間: 2025-3-27 07:52 作者: 廢墟 時(shí)間: 2025-3-27 10:35
Strategies for siRNA Navigation to Desired Cells,s now enabled efficient gene silencing in the desired cell populations/tissues in vitro and in vivo. The present review summarizes these current innovations, which are important for the design of safe therapeutic siRNAs.作者: enumaerate 時(shí)間: 2025-3-27 14:44
Use of Guanidinopropyl-Modified siRNAs to Silence Gene Expression, in vivo models of hepatitis B virus replication. Here we describe the synthesis of GP-modified siRNAs and use of 5′ rapid amplification of cDNA ends (5′ RACE) to verify an RNAi-mediated mechanism of action of these novel chemically modified siRNAs.作者: 遠(yuǎn)足 時(shí)間: 2025-3-27 17:47 作者: Diverticulitis 時(shí)間: 2025-3-27 23:56 作者: 依法逮捕 時(shí)間: 2025-3-28 04:43 作者: Mitigate 時(shí)間: 2025-3-28 07:14 作者: 肥料 時(shí)間: 2025-3-28 12:44 作者: 吵鬧 時(shí)間: 2025-3-28 18:32
Magnetic Nanoparticle and Magnetic Field Assisted siRNA Delivery In Vitro,on using self-assembled complexes of small interfering RNA (siRNA) and cationic lipids or polymers that are associated with magnetic nanoparticles (MNPs). These magnetic complexes are targeted to the cell surface by the application of a gradient magnetic field. A further development of the magnetic 作者: Culmination 時(shí)間: 2025-3-28 22:49
Cytoplasmic Delivery of siRNAs to Monocytes and Dendritic Cells via Electroporation,lence disease genes. However, the therapeutic use of siRNA faces the in vivo delivery challenge. An alternative method that could potentially be used for siRNA delivery into primary immune cells for therapeutic purposes is an ex vivo route, whereby immune cells could be isolated from a patient, repr作者: Stress 時(shí)間: 2025-3-28 23:17
Delivery of siRNAs to Cancer Cells via Bacteria,tacle for the development of RNAi-based therapeutic approaches is the delivery of the RNAi effector molecules to target cells. One promising strategy to surmount this challenge is the application of nonpathogenic bacteria as a delivery vector to target cells. In this chapter, the design of invasive 作者: 貪心 時(shí)間: 2025-3-29 04:55 作者: Negligible 時(shí)間: 2025-3-29 09:41 作者: nugatory 時(shí)間: 2025-3-29 15:20
Targeted In Vivo Delivery of siRNA and an Endosome-Releasing Agent to Hepatocytes,way: by co-opting a natural process to inhibit gene expression at the mRNA level. Given that siRNAs must interact with the cells’ natural RNAi machinery in order to exert their silencing effect, one of the most fundamental requirements for their use is efficient delivery to the desired cell type and作者: 顧客 時(shí)間: 2025-3-29 15:43
Cell-Internalization SELEX: Method for Identifying Cell-Internalizing RNA Aptamers for Delivering sut RNAi-based drugs. Phase I and II studies have shown safe, strong, and durable-gene knockdown (80–90 %, lasting for a month after a single injection) and/or clinical benefit in treating several liver pathologies. Although promising, these studies have also highlighted the need for robust . techniq作者: Vital-Signs 時(shí)間: 2025-3-29 20:13
Strategies for siRNA Navigation to Desired Cells,he most serious obstacle to siRNA drug development. As the most used delivery agents can enter all cell types, specificity must be built into the delivery agents or directly attached to the siRNA molecules. The use of antibodies, peptides, Peptide-Fc fusions, aptamers, and other targeting ligands ha作者: 爭吵 時(shí)間: 2025-3-30 01:48
Use of Guanidinopropyl-Modified siRNAs to Silence Gene Expression, therapeutic application. To augment silencing efficacy of siRNAs, chemical modification has been employed to improve stability, target specificity, and delivery to target tissues. siRNAs incorporating guanidinopropyl (GP) moieties have demonstrated enhanced target gene silencing in cell culture and作者: 思想靈活 時(shí)間: 2025-3-30 06:02 作者: 粗鄙的人 時(shí)間: 2025-3-30 09:50 作者: 知識分子 時(shí)間: 2025-3-30 16:25 作者: 隱語 時(shí)間: 2025-3-30 18:38 作者: AMPLE 時(shí)間: 2025-3-30 22:04
A Facile Method for Interfering with Off-Target Silencing Mediated by the Sense Strand,ng can limit their therapeutic use. Off-targeting can be identified for both the sense and antisense siRNA strands. Some avenues of obstructing the incorporation of the sense strand into the RNA-induced silencing complex (RISC) are currently being pursued. Herein, a biotin group at the 5′-end of the作者: 吹牛需要藝術(shù) 時(shí)間: 2025-3-31 03:29
Overcoming the Challenges of siRNA Activation of Innate Immunity: Design Better Therapeutic siRNAs, exogenously double-stranded RNA as small interfering (si) RNAs. To date, the use of siRNA (21-nt) has become a standard laboratory tool to silence gene expression in mammalian cells in-vitro and in-vivo. The methodology also holds promise for treating a diversity of human diseases. However, one of 作者: choleretic 時(shí)間: 2025-3-31 05:28 作者: 追蹤 時(shí)間: 2025-3-31 11:08 作者: 巫婆 時(shí)間: 2025-3-31 13:21 作者: 拾落穗 時(shí)間: 2025-3-31 21:14
