標(biāo)題: Titlebook: RNA Design; Methods and Protocol Alexander Churkin,Danny Barash Book 2025 The Editor(s) (if applicable) and The Author(s), under exclusive [打印本頁] 作者: 自由才謹(jǐn)慎 時(shí)間: 2025-3-21 17:53
書目名稱RNA Design影響因子(影響力)
書目名稱RNA Design影響因子(影響力)學(xué)科排名
書目名稱RNA Design網(wǎng)絡(luò)公開度
書目名稱RNA Design網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱RNA Design被引頻次
書目名稱RNA Design被引頻次學(xué)科排名
書目名稱RNA Design年度引用
書目名稱RNA Design年度引用學(xué)科排名
書目名稱RNA Design讀者反饋
書目名稱RNA Design讀者反饋學(xué)科排名
作者: tolerance 時(shí)間: 2025-3-21 22:47
1064-3745 e laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls...?..Authoritative and cutting-edge,?.RNA Design: Methods and Protocols .aims to ensure successful results in the further study of this vital field..978-1-0716-4081-4978-1-0716-4079-1Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 災(zāi)禍 時(shí)間: 2025-3-22 04:05
Sequence Design Using RNAstructure, is that objective functions need to consider the folding ensemble of RNA molecules to avoid off target structures. In this chapter, we provide protocols for two software tools from the RNAstructure package: “Design” for structured RNA sequence design and “orega” for unstructured RNA sequence design.作者: 否認(rèn) 時(shí)間: 2025-3-22 04:52 作者: 不規(guī)則的跳動(dòng) 時(shí)間: 2025-3-22 11:46
SHAPE Probing to Screen Computationally Designed RNA,n addition, it necessitates the analysis and evaluation of many experimental results that may reveal to be very tedious. Here we propose an experimental and analytical workflow that eases the screening of thousands of designed RNA sequences at once. In particular, we have developed . a customized software suite available at ..作者: Merited 時(shí)間: 2025-3-22 15:54 作者: buoyant 時(shí)間: 2025-3-22 18:53
Datasets for Benchmarking RNA Design Algorithms,asets to assess these programs. Here, we present a large dataset of internal and multibranched loops extracted from PDB-deposited RNA structures that encompass a wide spectrum of design difficulties. Furthermore, we conducted benchmarking tests of widely utilized open-source RNA design algorithms employing this dataset.作者: calamity 時(shí)間: 2025-3-22 23:22
Machine Learning for RNA Design: LEARNA,ncepts of reinforcement learning and its extension, automated reinforcement learning, and outline how these concepts can be successfully applied to the design of RNAs. The chapter is structured to guide through the usage of the different programs with explicit examples, highlighting particular applications of the individual tools.作者: Soliloquy 時(shí)間: 2025-3-23 04:52
Simulated Annealing for RNA Design with SIMARD,oblem and approached with simple heuristics. The main focus of this paper is to describe an RNA design algorithm based on simulated annealing. Additionally, noteworthy features and results will be presented herein.作者: 弄污 時(shí)間: 2025-3-23 06:14 作者: 走調(diào) 時(shí)間: 2025-3-23 13:23
Sequence Design for RNA-RNA Interactions,gy and biomedicine. Most regulatory RNAs function by forming RNA-RNA interactions, e.g., in order to regulate mRNA expression. It is therefore natural to consider problems where a sequence is designed to form a desired RNA-RNA interaction and switch between structures upon binding. This contribution作者: nepotism 時(shí)間: 2025-3-23 14:34 作者: 誹謗 時(shí)間: 2025-3-23 18:04 作者: 禍害隱伏 時(shí)間: 2025-3-23 22:49
Complex In Silico RNA Design with MoiRNAiFold, be effective tools in practical contexts. Moreover, it is of utmost importance to develop and provide access to computational tools capable of designing such RNA constructs. Here we introduce one such novel diagnostics technology (Apta-SMART) and show how to design (using MoiRNAiFold) and implement作者: 決定性 時(shí)間: 2025-3-24 05:58
Machine Learning for RNA Design: LEARNA,arkable results. In this chapter, we describe machine learning approaches specifically developed for the design of RNAs, with a focus on the learna_tools Python package, a collection of automated deep reinforcement learning algorithms for secondary structure-based RNA design. We explain the basic co作者: invade 時(shí)間: 2025-3-24 07:27 作者: CANE 時(shí)間: 2025-3-24 12:13
RNA Design Using incaRNAfbinv Demonstrated with the Identification of Functional RNA Motifs in Hepantemporary RNA design techniques, in addition to improved efficiency, offer more precise control over the designed sequences. incaRNAfbinv (incaRNAtion with RNA fragment-based inverse) is one such extension that builds upon RNAinverse and includes coarse-graining manipulations. The idea is that an R作者: 顯示 時(shí)間: 2025-3-24 15:35
gRNAde: A Geometric Deep Learning Pipeline for 3D RNA Inverse Design,ariety of distinct 3D states. Currently, computational RNA design tasks are often posed as inverse problems, where sequences are designed based on adopting a single desired secondary structure without considering 3D geometry and conformational diversity. In this tutorial, we present ., a .eometric .作者: CAGE 時(shí)間: 2025-3-24 20:19
Toward Increasing the Credibility of RNA Design,ssible free energy and under certain constraints. The designed sequences have applications in synthetic biology and RNA-based nanotechnologies. There are also known cases of the successful use of inverse folding to discover previously unknown noncoding RNAs. Several computational methods have been d作者: 去世 時(shí)間: 2025-3-25 01:34
3D-Based RNA Function Prediction Tools in , in RNA design. However, building datasets of RNA 3D structures and making appropriate modeling choices remain time-consuming and lack standardization. In this chapter, we describe the use of ., to train supervised and unsupervised machine learning-based function prediction models on datasets of RNA作者: pacifist 時(shí)間: 2025-3-25 04:02 作者: Vaginismus 時(shí)間: 2025-3-25 10:57
SHAPE Probing to Screen Computationally Designed RNA,esign pipelines is based on trial and error strategies. The fast progression of such algorithms requires assaying the properties of many RNA sequences in a short time frame. High throughput RNA structure chemical probing technologies such as SHAPE-MaP allow for assaying RNA structure and interaction作者: Factual 時(shí)間: 2025-3-25 12:59
A Computational Approach for Designing Synthetic Riboswitches for Next-Generation RNA Therapeutics,erve as a molecular ‘switch’ that controls the RNA’s structure and function, typically influencing the synthesis of proteins. Riboswitches are unique because they directly interact with metabolites without the need for proteins, making them attractive tools in synthetic biology and RNA-based therape作者: HAWK 時(shí)間: 2025-3-25 17:41
Monte Carlo Inverse RNA Folding,out Policy Adaptation (GNRPA) is a Monte Carlo search algorithm for optimizing a sequence of choices. It learns a playout policy to intensify the search of the state space near the current best sequence. The algorithm uses a prior on the possible actions so as to perform non uniform playouts when le作者: 爵士樂 時(shí)間: 2025-3-25 21:13 作者: Uncultured 時(shí)間: 2025-3-26 03:07 作者: sterilization 時(shí)間: 2025-3-26 05:30
,The Evolution of Nucleic Acid–Based Diagnosis Methods from the (pre-)CRISPR to CRISPR era and the A, trace and genotype detection of pathogens and pathogenic variants, various types of NATs have been developed since the discovery of PCR. As alternatives to traditional NATs (e.g., PCR), isothermal nucleic acid amplification techniques (INAATs) such as LAMP, RPA, SDA, HDR, NASBA, and HCA were inven作者: inhumane 時(shí)間: 2025-3-26 09:51
1064-3745 ation advice from the experts.This volume provides comprehensive methods on RNA design. Chapters details traditional RNA design in secondary structure, ?RNA design in tertiary structure, and RNA design applications and assessments. Written in the highly successful?.Methods in Molecular Biology.?seri作者: 真繁榮 時(shí)間: 2025-3-26 16:08
Complex In Silico RNA Design with MoiRNAiFold,ing such RNA constructs. Here we introduce one such novel diagnostics technology (Apta-SMART) and show how to design (using MoiRNAiFold) and implement it, step by step. Moreover, we show how to combine this technique with well-known RNA amplification methods and briefly mention some encouraging results.作者: 極少 時(shí)間: 2025-3-26 17:42
Methods in Molecular Biologyhttp://image.papertrans.cn/r/image/820156.jpg作者: 牌帶來 時(shí)間: 2025-3-26 21:58 作者: 入伍儀式 時(shí)間: 2025-3-27 02:08
978-1-0716-4081-4The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines作者: 錯(cuò) 時(shí)間: 2025-3-27 09:16 作者: abysmal 時(shí)間: 2025-3-27 12:12
Alexander Churkin,Danny BarashIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts作者: SYN 時(shí)間: 2025-3-27 14:19 作者: Capitulate 時(shí)間: 2025-3-27 18:46
3D-Based RNA Function Prediction Tools in , in RNA design. However, building datasets of RNA 3D structures and making appropriate modeling choices remain time-consuming and lack standardization. In this chapter, we describe the use of ., to train supervised and unsupervised machine learning-based function prediction models on datasets of RNA 3D structures.作者: 啞巴 時(shí)間: 2025-3-28 01:08 作者: 多山 時(shí)間: 2025-3-28 03:35 作者: CURT 時(shí)間: 2025-3-28 07:08 作者: Generic-Drug 時(shí)間: 2025-3-28 11:47 作者: 大方一點(diǎn) 時(shí)間: 2025-3-28 15:37 作者: 休閑 時(shí)間: 2025-3-28 19:29 作者: 名義上 時(shí)間: 2025-3-29 00:44
,The Evolution of Nucleic Acid–Based Diagnosis Methods from the (pre-)CRISPR to CRISPR era and the Athe role CRISPR-based technologies have played in molecular diagnosis. Here we provide examples of a few groundbreaking CRISPR assays that have been developed to counter epidemics and pandemics and outline CRISPR biology, highlighting the role of CRISPR guide RNA and its design in any successful CRI作者: 易達(dá)到 時(shí)間: 2025-3-29 03:26
Frederic Runge,Frank HutterGovernance“ entwickelt und spezifiziert werden. Es handelt sich um ein Steuerungs- und Regelungssystem, welches Organisationen und ihre Besch?ftigten in Zeiten der Digitalisierung erfolgreich in die Zukunft führt.?.978-3-658-37173-9978-3-658-37174-6作者: 新字 時(shí)間: 2025-3-29 08:48 作者: 走路左晃右晃 時(shí)間: 2025-3-29 13:01
Rami Zakh,Alexander Churkin,Danny Barashin development elements of the EAEU e-governance development institution: Strategic central project office. That is the organization, created by the Eurasian Economic Commission and dealing with planning and control of the cross-boundary project activity between EAEU members, providing methodologica作者: 難聽的聲音 時(shí)間: 2025-3-29 16:36
Chaitanya K. Joshi,Pietro Liòcapabilities of a political organization interested in civil participation and the design of the participation process. The possible examples of immersive journalism and its gamified product, newsgames, in Russian realities are such information resources as “Lentach” and “Meduza”. New digital produc作者: Excitotoxin 時(shí)間: 2025-3-29 21:13
Maciej Antczak,Marta Szachniukorruption. In conclusion, with most of the papers containing no theoretical references, the field is still clearly struggling with theory. The article discusses the benefits with appropriating theory, such as principal-agent and collective action as well as more critical approaches to un-pack ICTs c作者: 多骨 時(shí)間: 2025-3-30 02:44 作者: Amplify 時(shí)間: 2025-3-30 04:34 作者: 苦惱 時(shí)間: 2025-3-30 10:19
Pierre Hardouin,Francois-Xavier Lyonnet du Moutier,Bruno Sargueilcy maker, the service provider and the user perspective. As a result, we identified five themes of common challenges: compliance issues, interpretation problems, different practices in member states, cooperation and collaboration barriers, and representation of legal persons. Proposed solutions do n作者: Callus 時(shí)間: 2025-3-30 15:09
Sumit Mukherjee,Sunanda Biswas Mukherjee,Danny Barashanced citizen participation at the regional level, providing a best practice example. The paper concludes by sharing some important lessons that can not only be learnt for Germany itself but also for aspiring fellow Eurasian states and municipalities pursuing Open Government.作者: laxative 時(shí)間: 2025-3-30 17:17
Tristan Cazenave,Hamza Touzanim “Digital economy” has given a new impulse and made a start to an open discussion on the perspective of recent adoption of a digital code. The authors seek to review existing regulation and doctrine in Russia to make suggestions on the content and structure of such a document.作者: 使苦惱 時(shí)間: 2025-3-30 21:57 作者: GRAVE 時(shí)間: 2025-3-31 03:03
Jan Badura,Tomasz Zok,Agnieszka Rybarczyksted on a study area that spans Alexandria, El Beheira and Matrouh governorates in Egypt. The prototype developed is a very beneficial instrument that enables facts based decision making as opposed to the current subjective practices used in selecting a SC location.作者: Irremediable 時(shí)間: 2025-3-31 08:45
Shruti Sarika Chakraborty,Jayati Ray Dutta,Ramakrishnan Ganesan,Peter Minaryellectualization of knowledge acquisition from academic texts it is necessary to present to the reader the results of the TS fulfilled by different algorithms, in a complex. A system of complex visualization of TS results is proposed, and an appropriate software solution is developed. The visualizat作者: 堅(jiān)毅 時(shí)間: 2025-3-31 12:33
roblog account type prediction framework “POP-MAP”. To study the problem at a cross-language level, we harvested and learned from a multi-lingual Twitter dataset, which allows us to achieve better classification performance, as compared to various state-of-the-art baselines. 作者: 發(fā)牢騷 時(shí)間: 2025-3-31 14:53 作者: micturition 時(shí)間: 2025-3-31 20:59 作者: champaign 時(shí)間: 2025-3-31 22:37
Rami Zakh,Alexander Churkin,Danny Barashrasian Economic Union (hereinafter EAEU): the Russian Federation, Belarus, Armenia, Kazakhstan and Kirgizstan. The article defines conceptual space for the category “Cross-boundary projects e-governance for the EAEU countries”. The paper analyses project management development in the EAEU countries 作者: amygdala 時(shí)間: 2025-4-1 04:16 作者: bronchodilator 時(shí)間: 2025-4-1 07:24 作者: Moderate 時(shí)間: 2025-4-1 11:02 作者: lacrimal-gland 時(shí)間: 2025-4-1 14:25
