標題: Titlebook: Paroxysmal Nocturnal Hemoglobinuria and Related Disorders; Molecular Aspects of Mitsuhiro Omine (Professor),Taroh Kinoshita (Profe Conferen [打印本頁] 作者: Philanthropist 時間: 2025-3-21 18:29
書目名稱Paroxysmal Nocturnal Hemoglobinuria and Related Disorders影響因子(影響力)
書目名稱Paroxysmal Nocturnal Hemoglobinuria and Related Disorders影響因子(影響力)學科排名
書目名稱Paroxysmal Nocturnal Hemoglobinuria and Related Disorders網絡公開度
書目名稱Paroxysmal Nocturnal Hemoglobinuria and Related Disorders網絡公開度學科排名
書目名稱Paroxysmal Nocturnal Hemoglobinuria and Related Disorders被引頻次
書目名稱Paroxysmal Nocturnal Hemoglobinuria and Related Disorders被引頻次學科排名
書目名稱Paroxysmal Nocturnal Hemoglobinuria and Related Disorders年度引用
書目名稱Paroxysmal Nocturnal Hemoglobinuria and Related Disorders年度引用學科排名
書目名稱Paroxysmal Nocturnal Hemoglobinuria and Related Disorders讀者反饋
書目名稱Paroxysmal Nocturnal Hemoglobinuria and Related Disorders讀者反饋學科排名
作者: restrain 時間: 2025-3-21 23:39
A Multistep Model for the Pathogenesis and Evolution of PNHransformation of PNH into myelodysplasia or leukemia are just several aspects of PNH that are poorly understood. Previous models for the development of PNH are somewhat simplistic and do not address each of these important questions. In this report, we suggest a new multistep model for the pathogenesis and evolution of PNH.作者: 公式 時間: 2025-3-22 01:24 作者: 聽寫 時間: 2025-3-22 06:04
Proposals for Classification of the Clinical Stages, Grading of Severity and the Molecular Pathogenesis of Paroxysmal Nocturnal Hemoglobinuriad manner plays an important role in the occurrence of a PNH clone, and that a PNH clone increases or decreases relatively or absolutely through competition between proliferation of WT1-expressing cells and clonal selection against WT1-expressing cells.作者: 一再困擾 時間: 2025-3-22 10:22
PNH clone acquires both a survival and a growth advantage?clonal expansion. Indeed, we have detected a preferential hematopoiesis by PNH stem cells when transplanted in mice, supporting the intrinsic growth alteration. Thus, we conclude that PNH clone acquires both a growth and a survival advantage.作者: 受辱 時間: 2025-3-22 15:32
The Role of Lymphoid Cells in the Pathogenesis of PNH attack, survive and expand. However, the mechanism responsible for the bone marrow failure and the target of the autoaggressive T cells remains still unknown. Here, we review the the most recent findings and possible mechanisms.作者: 通便 時間: 2025-3-22 18:50 作者: CANT 時間: 2025-3-23 00:03
Overview of Paroxysmal Nocturnal Hemoglobinuria: Molecular Geneticswith aplastic anemia have clearly recognizable PIG-A mutant clone. These findings suggest that somatic mutation of PIG-A occurs in normal individuals and that clonal expansion requires extra event(s), such as selection by some pathological condition and/or some additional genetic change.作者: 假 時間: 2025-3-23 02:23 作者: STRIA 時間: 2025-3-23 05:34
Clinical Pathology and natural history of PNH; The French Society of Hematology experience.rogens led to an increased risk of death (～ 5 fold) in patients with . PNH while it lowered the risk of death (～ 4 fold) in patients with the AA-PNH syndrome, compared to patients treated by androgens in either group.作者: 痛苦一生 時間: 2025-3-23 12:11 作者: 單片眼鏡 時間: 2025-3-23 14:29 作者: 反感 時間: 2025-3-23 19:28
Paroxysmal Nocturnal Hemoglobinuria and Related DisordersMolecular Aspects of作者: calorie 時間: 2025-3-24 00:44 作者: 說笑 時間: 2025-3-24 04:23 作者: 較早 時間: 2025-3-24 09:32
Tsutomu Shichishimatschen Nationalversammlung von 1848, jenes gesamtdeutschen Repr?sentativorgans, dessen Mitglieder sich angeschickt hatten, zum erstenmal auf deutschem Boden eine freiheitliche und demokratische Verfassung auszuarbeiten und somit der deutschen Geschichte eine grundlegende Richtungs?nderung zu geben. 作者: 可以任性 時間: 2025-3-24 12:39
Wendell F. Rosse M.D.tschen Nationalversammlung von 1848, jenes gesamtdeutschen Repr?sentativorgans, dessen Mitglieder sich angeschickt hatten, zum erstenmal auf deutschem Boden eine freiheitliche und demokratische Verfassung auszuarbeiten und somit der deutschen Geschichte eine grundlegende Richtungs?nderung zu geben. 作者: vascular 時間: 2025-3-24 17:09
Gérard Socié M.D., Ph.D.,Jean-Yves Mary Ph.Drückgelegten Weg, über die noch zu bew?ltigenden Aufgaben, über die Verfassung insgesamt, in der sie selbst und die res publica, das Gemeinwesen, sich befinden. In diesem Sinne will ich versuchen, einige tragende Ideen der Verfassung exemplarisch vorzustellen und daran die Frage zu knüpfen, ob und w作者: 修飾 時間: 2025-3-24 20:37
Hideki Nakakuma,Tatsuya Kawaguchieiterstreik des Jahres 1951 (1983). Die ?Geschichte der hessischen Arbeiterbewegung“ ist neuerdings von Gerhard Beier bearbeitet worden (1984). Sie bleibt freilich für die Zeit nach 1945 h?chst allgemein und fragmentarisch. Der biographische Anhang (S. 355ff.) sowie das Literaturverzeichnis sind all作者: 休閑 時間: 2025-3-25 02:48
Norimitsu Inoue,Tomohisa Izui,Maki Kuwayama,Jun-ichi Nishimura,Ken Kurokawa,Takashi Machii,Yuzuru Kanakura,Taroh. Kinoshitarn, sondern auch die Perspektiven einer Nutzung der Arbeitskraft dieser Gruppe — und damit der Ma?nahmen, die zu einer Integration ?lterer und leistungsgemindeter Arbeitnehmer in den Arbeitsmarkt beitragen.作者: sleep-spindles 時間: 2025-3-25 07:13 作者: POWER 時間: 2025-3-25 09:34 作者: propose 時間: 2025-3-25 13:12 作者: Cleave 時間: 2025-3-25 15:56 作者: DAUNT 時間: 2025-3-25 20:29 作者: 不規(guī)則的跳動 時間: 2025-3-26 03:17
A Multistep Model for the Pathogenesis and Evolution of PNHwitnessed remarkable progress toward a better understanding of the pathogenesis and pathophysiology of this mysterious blood disorder. After multiple proteins were found to be absent from the surface of PNH cells, it was recognized that each utilized a glycosylphosphatidylinositol (GPI) anchor for c作者: debase 時間: 2025-3-26 08:13 作者: Prosaic 時間: 2025-3-26 11:33 作者: CLEAR 時間: 2025-3-26 14:29
PNH clone acquires both a survival and a growth advantage?rest is the mechanism by which PNH clone expands to manifest clinical symptoms. Gene targeting showed that clonal dominance is not attributable to . mutation alone. For the expansion, there are two hypotheses of a survival and a growth advantage. Increasing evidence has shown that an immune mechanis作者: Aggressive 時間: 2025-3-26 20:42 作者: INCUR 時間: 2025-3-26 22:06 作者: 消音器 時間: 2025-3-27 01:17 作者: Modicum 時間: 2025-3-27 07:35 作者: Euphonious 時間: 2025-3-27 09:41
The Enigma of the Aplastic Anemia/PNH Syndroment in patients recovering from aplastic anemia. Better understanding of the pathophysiology of both diseases and improved tests for cell surface glycosylphosphatidylinositol (GPI)-linked proteins have radically altered this view. Flow cytometry of granulocytes shows evidence of an expanded PNH clone作者: instulate 時間: 2025-3-27 13:50 作者: laparoscopy 時間: 2025-3-27 18:02
