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標(biāo)題: Titlebook: Organic Cation Transporters in the Central Nervous System; Lynette C. Daws Book 2021 The Editor(s) (if applicable) and The Author(s), unde [打印本頁]

作者: 要旨    時間: 2025-3-21 18:37
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作者: 廣口瓶    時間: 2025-3-21 21:01
Organic Cation Transporters in the Central Nervous System978-3-030-82984-1Series ISSN 0171-2004 Series E-ISSN 1865-0325
作者: Arb853    時間: 2025-3-22 01:17
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/o/image/703783.jpg
作者: JADED    時間: 2025-3-22 05:33
https://doi.org/10.1007/978-3-030-82984-1organic cation transporter (OCT); plasma membrane monoamine transporter (PMAT); monoamine homeostasis;
作者: 辭職    時間: 2025-3-22 12:46
Lynette C. DawsFirst book that comprehensively synthesizes literature pertaining to the role of OCTs and PMAT in the CNS.Lays emphasis on health, disease and therapeutics.Highlights the important role for OCTs and P
作者: 滲入    時間: 2025-3-22 14:16

作者: outskirts    時間: 2025-3-22 19:47
Organic Cation Transporter Expression and Function in the CNS,. In particular, transporters belonging to the Solute Carrier (SLC) superfamily are emerging as major contributors, including the SLC22 organic cation/anion/zwitterion family of transporters (includes OCT1–3 and OCTN1–3), the SLC29 facilitative nucleoside family of transporters (includes PMAT), and
作者: Indelible    時間: 2025-3-23 00:53
Experimental Methods for Investigating Uptake 2 Processes In Vivo,ve yielded important information about Uptake 2 mechanisms in vivo. The techniques (scintillation microspectrophotometry, microdialysis, chronoamperometry, and voltammetry) are described in detail, and pivotal studies associated with each method are highlighted. It is clear from these reviewed works
作者: Adjourn    時間: 2025-3-23 02:11
Organic Cation Transporters in Brain Histamine Clearance: Physiological and Psychiatric Implicationine transport have indicated the contribution of organic cation transporter 3 (OCT3) and plasma membrane monoamine transporter (PMAT) in histamine uptake, although the importance of these transporters in in vivo histamine clearance remains unknown. Immunohistochemical analyses have revealed the expr
作者: 無目標(biāo)    時間: 2025-3-23 09:02
Organic Cation Transporters in Brain Catecholamine Homeostasis, are expressed widely throughout the brain. In contrast to DAT and NET, these transporters have higher capacity and lower affinity for catecholamines and are multi-specific, each with the capacity to transport all catecholamines. The expression of these transporters in the brain suggests that they p
作者: Explicate    時間: 2025-3-23 09:51

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作者: MILL    時間: 2025-3-24 09:34
Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Deliverye CNS. Organic Cation Transporters (OCTs) and Novel Organic Cation Transporters (OCTNs) are two subfamilies of the solute carrier 22 (SLC22) family of proteins that have significant potential to mediate delivery of positively charged, zwitterionic, and uncharged therapeutics. While expression of the
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作者: 舉止粗野的人    時間: 2025-3-24 22:31
Hermann Koepsellonsidered to be a serious consequence of influenza virus infection worthy of prevention. Recent surveys have shown that only about one quarter of patients hospitalized with ARD during influenza epidemics are 65 years of age or older and that only 31% have underlying chronic conditions for which vacc
作者: 我悲傷    時間: 2025-3-24 23:31
Douglas H. Sweetresponsible for the majority of cases of parenterally transmitted non-A, non-B hepatitis and produces a persistent infection that is often associated with chronic liver disease. Hepatitis E virus (HEV) is the cause of almost all cases of enterically transmitted non-A, non-B hepatitis and is not know
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作者: floaters    時間: 2025-3-25 13:54
Heinz B?nisch wounded soldier or patient can be acquired in electronic form and transmitted to a physician at a computer workstation. With the technologies of teleoperation, telemanipulation and telesurgery, the physician can bring expertise to the place where the soldier is wounded or the patient is sick. In ad
作者: 吸氣    時間: 2025-3-25 15:52

作者: Lasting    時間: 2025-3-25 23:47
Paul J. Gasser wounded soldier or patient can be acquired in electronic form and transmitted to a physician at a computer workstation. With the technologies of teleoperation, telemanipulation and telesurgery, the physician can bring expertise to the place where the soldier is wounded or the patient is sick. In ad
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作者: 駕駛    時間: 2025-3-26 04:38

作者: 燦爛    時間: 2025-3-26 10:46
Kelsey C. Benton,Christopher A. Lowry,Paul J. Gasserly, the brain is forced out of the skull by the build-up of pressure within it. This is known as herniation of the brain. It is accompanied by loss of consciousness and, if unchecked, may progress to coma and death. Lesser degrees of intracranial pressure while not fatal, result in compromise of neu
作者: obsession    時間: 2025-3-26 14:50
Letícia S. Vieira,Joanne Wangly, the brain is forced out of the skull by the build-up of pressure within it. This is known as herniation of the brain. It is accompanied by loss of consciousness and, if unchecked, may progress to coma and death. Lesser degrees of intracranial pressure while not fatal, result in compromise of neu
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作者: 指數(shù)    時間: 2025-3-26 20:56

作者: hegemony    時間: 2025-3-27 02:40

作者: 小教堂    時間: 2025-3-27 06:15
Organic Cation Transporter Expression and Function in the CNS,ive control over the movement of organic cations and anions into and out of the CNS compartment. In addition, multiple CNS cell types, e.g., astrocytes, ependymal cells, microglia, contribute to processes that maintain the status quo of the CNS milieu. To fulfill their roles, these barriers and cell
作者: 粉筆    時間: 2025-3-27 13:27
Genetic and Epigenetic Regulation of Organic Cation Transporters,any clinically-relevant drugs such as the antidiabetic agent metformin, the opioid tramadol, and the antimigraine agent sumatriptan. OCT1 (.) and OCT2 (.) are highly expressed in human liver and kidney, respectively, while OCT3 (.) shows a broader tissue distribution. As suggested from studies using
作者: 收到    時間: 2025-3-27 16:01

作者: FLAG    時間: 2025-3-27 19:16

作者: 談判    時間: 2025-3-27 22:03

作者: Spirometry    時間: 2025-3-28 02:59
Organic Cation Transporters in Brain Catecholamine Homeostasis,n. Collectively, catecholamines exert powerful regulation of mood, motivation, arousal, and plasticity. Transporter-mediated uptake determines the peak concentration, duration, and physical spread of released catecholamines, thus playing key roles in determining the magnitude and duration of their m
作者: 死亡    時間: 2025-3-28 08:27
The Interaction of Organic Cation Transporters 1-3 and PMAT with Psychoactive Substances,oaminergic equilibrium in the central nervous system. With many psychoactive substances interacting with OCT1-3 and PMAT, a growing literature focuses on characterizing their properties via in vitro and in vivo studies. In vitro studies mainly aim at characterizing compounds as inhibitors or substra
作者: 細胞膜    時間: 2025-3-28 14:01

作者: 小說    時間: 2025-3-28 14:37

作者: GNAW    時間: 2025-3-28 20:20
Brain Plasma Membrane Monoamine Transporter in Health and Disease, signaling is associated with several neuropsychiatric and neurodegenerative disorders. The plasma membrane monoamine transporter (PMAT) is a new polyspecific organic cation transporter encoded by the . gene. Capable of transporting monoamine neurotransmitters with low affinity and high capacity, PM
作者: 蝕刻    時間: 2025-3-29 01:00
Regulation of Neurogenesis by Organic Cation Transporters: Potential Therapeutic Implications, differentiate into neurons, astrocytes, and oligodendrocytes. The process is essential for homeostatic tissue regeneration and the coordination of neural plasticity throughout life, as neurons cannot regenerate once injured. Therefore, defects in neurogenesis are related to the onset and exacerbati
作者: 流動性    時間: 2025-3-29 07:03
Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Deliveryeurological disorders. This is primarily due to the physiological and biochemical characteristics of brain barrier sites (i.e., blood–brain barrier (BBB), blood–cerebrospinal fluid barrier (BCSFB)). Drug uptake into brain tissue is highly restricted by expression of tight junction protein complexes
作者: Infelicity    時間: 2025-3-29 08:00
rials and exercises on how to create functional extensions.D.Master Visual Studio extensibility for an enhanced Visual Studio IDE experience. This book is a comprehensive guide that covers every facet of developing, debugging, and publishing extensions that amplify your productivity, tooling, and an
作者: Immunotherapy    時間: 2025-3-29 13:28
Hermann Koepsell of all ages in all parts of the world,. including both temperate and tropical climates. Acute respiratory diseases, to which influenza is a major contributor, rival gastroenteritis as the principal cause of morbidity and mortality throughout the world. Epidemics occur annually, and, although they v
作者: omnibus    時間: 2025-3-29 17:43
Douglas H. Sweetn acute self-limited disease resulting from infection with hepatitis A virus (HAV). Infection with hepatitis B virus (HBV) can produce a chronic infection that places the individual at risk of death from chronic liver disease or primary hepatocellular carcinoma. Delta hepatitis is caused by hepatiti
作者: Altitude    時間: 2025-3-29 20:39
Charlotte K?lz,Elke Schaeffeler,Matthias Schwab,Anne T. Nies of all ages in all parts of the world,. including both temperate and tropical climates. Acute respiratory diseases, to which influenza is a major contributor, rival gastroenteritis as the principal cause of morbidity and mortality throughout the world. Epidemics occur annually, and, although they v
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作者: 使激動    時間: 2025-3-30 08:31

作者: DOLT    時間: 2025-3-30 14:09
Paul J. Gasserical and surgical intervention, informatics, virtual prototyping and simulation. In 1994, an informal estimate given during a National Science Foundation workshop suggested that 90% of the information desired by a physician to treat a patient can be acquired electronically. Examples included non-inv
作者: remission    時間: 2025-3-30 16:31
Julian Maier,Marco Niello,Deborah Rudin,Lynette C. Daws,Harald H. Sitte effort has started to be made to prove or disprove the possibility that “therapeutic vaccines” may have more than just anecdotal efficacy against cancer. The recognition that the immune system could be stimulated into rejecting established tumour came from the work of Coley (1893/1894) who refined
作者: 凹室    時間: 2025-3-31 00:37
Lynette C. Dawses have shown the existence of two types of Th cells that could be distinguished on the basis of their cytokine production (Mosmann et al., 1986; Mosmann and Coffman, 1989). The Th1 subset secretes IL-2 and IFN-γ, and preferentially promotes cell-mediated immunity and IgG2a production by B lymphocyt




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