標題: Titlebook: Organ-Selective Actions of Steroid Hormones; D. T. Baird,G. Schütz,R. Krattenmacher Conference proceedings 1995 Springer-Verlag Berlin Hei [打印本頁] 作者: 天真無邪 時間: 2025-3-21 17:03
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作者: 闡明 時間: 2025-3-21 23:55
Estrogen-Receptor and Antiestrogen-Receptor Complexes: Cell- and Promoter-Specific Effects and Inte to effectively activate gene transcription (Jordan and Murphy 1990; Katzenellenbogen et al. 1985; Santen et al. 1990). Two of the major challenges in studies on antiestrogens are to understand what accounts for their antagonistic effectiveness, as well as the partial agonistic effects of some antie作者: inconceivable 時間: 2025-3-22 03:08 作者: HILAR 時間: 2025-3-22 06:29 作者: 靦腆 時間: 2025-3-22 11:11 作者: NEX 時間: 2025-3-22 15:44 作者: osteocytes 時間: 2025-3-22 18:14
Organ-Specific Actions of Vitamin D Analogs: Relevance of Rapid Effects,considerable attention of late is its ability to stimulate rapid actions in target cells. These rapid actions include stimulation of lipid turnover (Lieberherr et al. 1989; DeBoland and Boland 1993), Ca. influx via plasma membrane voltage-sensitive Ca. channels (Caffrey and Farach-Carson 1989; DeBol作者: 相符 時間: 2025-3-22 23:28 作者: diathermy 時間: 2025-3-23 03:25
R. L. Sutherland,C. S. L. Lee,A. L. Cornish,E. A. Musgrove作者: Lumbar-Stenosis 時間: 2025-3-23 09:26 作者: 收集 時間: 2025-3-23 10:30
Organ-Selective Actions of Tamoxifen and Other Partial Antiestrogens,ures, indicating that estrogen deficiency alone is insufficient to fully account for the disorder. An increased understanding of the mechanisms whereby estrogen interacts with other factors to maintain bone balance is an important step in improving hormone replacement therapy in postmenopausal women.作者: 有權威 時間: 2025-3-23 14:24
Androgen Action on the Bone, lose about 30% of their trabecular bone and 20% of their cortical bone. Thus, even though osteoporosis is less common in men than in women, one fifth of all hip fractures occur in men and by the age of 90 one of every six men will have fractured his hip.作者: 墻壁 時間: 2025-3-23 19:16
Conference proceedings 1995h the goal of attaining a better understanding of the underlying mechanisms of organ selective actions of steroids. Discussed is the extent to which tissue specificity might selectively be modified by chemical modification of the hormones and how this may be applied towards improved therapies by taking advantage of tissue selectivity.作者: 控訴 時間: 2025-3-24 01:38
0947-6075 y has opened the way for more detailed investigation of the complex set of intracellular interactions contributing to organ-selective actions of steroids and steroid-like compounds such as vitamin D. In this volume leading experts address basic molecular mechanisms of tissue specificity and related 作者: 嘲弄 時間: 2025-3-24 05:08
Conference proceedings 1995ed the way for more detailed investigation of the complex set of intracellular interactions contributing to organ-selective actions of steroids and steroid-like compounds such as vitamin D. In this volume leading experts address basic molecular mechanisms of tissue specificity and related issue, wit作者: MUTE 時間: 2025-3-24 08:35 作者: 結(jié)果 時間: 2025-3-24 13:01
Organ-Selective Actions of Steroid Hormones978-3-662-09153-1Series ISSN 0947-6075 作者: BLAND 時間: 2025-3-24 17:18 作者: 嘲笑 時間: 2025-3-24 18:59
https://doi.org/10.1007/978-3-662-09153-1Gewebe; Hormone replacement therapy; Hormontherapie; Osteoporose; Promoter; Steroide; Tissue specificity; V作者: enormous 時間: 2025-3-25 00:49
Development of Tissue-Selective Estrogen Receptor Modulators,roductive function (Clark and Peck 1979). In pathological states, estrogen is also involved in the maintenance and progression of cancers (Sunderland and Osborne 1991) and is implicated in the abnormalities of uterine function observed in endometriosis and possibly uterine fibroids (Kettel et al. 19作者: 逢迎春日 時間: 2025-3-25 05:50
Estrogen-Receptor and Antiestrogen-Receptor Complexes: Cell- and Promoter-Specific Effects and Inteuding bone, liver, and the cardiovascular system. Most of the actions of estrogens appear to be exerted via the estrogen receptor (ER) of target cells, an intracellular receptor that is a member of a large superfamily of proteins that function as ligand-activated transcription factors, regulating th作者: 慎重 時間: 2025-3-25 10:04 作者: nettle 時間: 2025-3-25 14:55 作者: uveitis 時間: 2025-3-25 19:02 作者: GRAZE 時間: 2025-3-26 00:00 作者: surrogate 時間: 2025-3-26 00:12
Androgen Action on the Bone,ely 1.5 million fractures each year (Finkelstein 1995). The annual cost of health care and lost productivity attributed to osteoporosis exceeds $10 billion in the United States. During the course of their lifetimes, women lose about 50% of their trabecular bone and 30% of the cortical bone while men作者: 煤渣 時間: 2025-3-26 05:50
General Principles of Vitamin D Action and Mechanism-Based Search for Analogs with Specific Actionsa 1974, 1988). First, 25-hydroxylation is carried out in the microsomes and mitochondria of liver to produce the circulating form of vitamin D 25-hydroxyvitamin D. (25-OH-D.). Secondly, 1α-hydroxylation produces the final hormonal or active form 1,25-dihydroxyvitamin D. (1,25-(OH).D.). In normal hum作者: 廢止 時間: 2025-3-26 08:27 作者: ANA 時間: 2025-3-26 16:34
Eldar Fischer,Orly Yahalomions from many eminent specialists across a variety of disciAssessment of human casualties in earthquakes has become a topic of vital importance for national and urban authorities responsible for emergency provision, for the development of mitigation strategies and for the development of adequate in作者: 合適 時間: 2025-3-26 18:58
Victoria Buchholz,Stefan Kopp diesem Satze Turgenjew’s giebt bie ?formale Bildung“ ein Beispiel. Das Wort ist ein Gespenst geworden, mit dem man die erwachsensten Menschen erschreckt. Wer das Gymnasium schelten will, der wirft ihm vor, da? es nichts weiter schaffe als formale Bildung; wer es vertheidigen will, der sucht sich vo作者: SLAG 時間: 2025-3-26 21:38
Ingrid Lewispresumably under the inspiration of the Egyptian uniconsonantal hieroglyphic signs, in the first half of the second millennium .. Had the Egyptians used only the uniconsonantal signs and let their bi- and triconsonantal pictographic symbols fall into disuse, their writing would have been alphabetic 作者: Glaci冰 時間: 2025-3-27 02:10 作者: 點燃 時間: 2025-3-27 07:03
Integrated Surface and Borehole Strong-Motion, Soil-Response Arrays in San Francisco, Californiaof soft-soil deposits to strong earthquake ground motions. The borehole arrays extend through thick layers of soft water-saturated soils of Holocene age and older more consolidated soils of Pleistocene age into bedrock at depths up to 90 m. The surface installations are configured in pairs to provid作者: cultivated 時間: 2025-3-27 10:39
Endokrinpharmakologiestanzen besprochen, soweit sie nicht in den klinischen Kapiteln in anderem Zusammenhang angemessen dargestellt ist. Entsprechend ihrer gro?en praktischen Bedeutung nehmen die Sexualsteroide und ihre synthetischen Abk?mmlinge einen breiten Raum ein. Sexualsteroide und ihre Derivate geh?ren weltweit z作者: 攤位 時間: 2025-3-27 17:14
Is Pharmacotherapy a Satisfactory Alternative Treatment for Benign Prostatic Hyperplasia?proximately 90% of patients will undergo a transurethral prostatectomy (Mebust, 1988) and this is the gold standard against which other therapies need to be judged. Prostatic surgery is associated with an improvement in patients’ symptoms in the majority of cases; 75% at 3 years in the series report作者: 瑣事 時間: 2025-3-27 17:58 作者: BARK 時間: 2025-3-27 22:00
R. L. Cliquet,E. van Hyfte,F. Devenung. Andererseits bilden St?dte Brennpunkte gesellschaftlicher Probleme und Konflikte, gelten sie als Orte der Desorganisation und Unsicherheit. Da beide Merkmale empirische Evidenz aufweisen, zeichnen sie zusammen die immer wieder irritierende Ambivalenz der Stadt.作者: 江湖郎中 時間: 2025-3-28 05:00 作者: Forage飼料 時間: 2025-3-28 09:34
Dynamics of Speed Climbingng speed, the higher are the finger reaction forces at the hold, the higher is the shock spike at initial contact, and the shorter is the contact time. As speed is a factor of experience, the contact time and the magnitude of forces also correlate with the experience.作者: 無聊點好 時間: 2025-3-28 11:09
https://doi.org/10.1007/978-3-642-02897-7vancing within the organization relied on these middle managers as well. In this chapter, we analyse the work of three middle managers to understand the realities of leading from the middle through identifying key dimensions, strategies and approaches adopted as well as the tensions they experienced作者: Largess 時間: 2025-3-28 16:35
Robin Kendalltters of Spatial and Resource Sciences. We let our contributors - velop, from their particular perspective and insights, their own strategies for m- ping the part of terrain for which they were responsible. As the chapters were submitted, we became the first consumers of the project we had initiated作者: dandruff 時間: 2025-3-28 21:37
?Macht und Geld regiert die Welt — und M?nner sind anf?llig dafür!“ Sechzehnj?hrige M?dchen und Jungchen Generationen uns objektiv dankbar sein müssten, subjektiv sind sie eher weit abgeschreckt, wenn sie nicht bereits milde l?cheln. L?ngst scheint für sie ?dieses ganze Gehabe“ nun nicht mehr n?tig, um den halben Himmel zu beziehen. Auf nichts werden sie mehr verzichten müssen: die Haus- und Famil作者: 生意行為 時間: 2025-3-28 23:32
Protecting Youth’s Relationships with Deployed Parentsr das Internet in diesem Buch sichtbar wird und ich vielleicht die eine oder den anderen damit anzustecken vermag. Nicht mit Begeisterung auf eine unkritische und vor- haltlose Art – aber indem vielleicht sicht978-3-540-78393-0作者: Abduct 時間: 2025-3-29 03:30
Navier-Stokes Equations: Accuracy Assessments and Numerical Results,upwinding techniques of chapter 2); ii) to review some theoretical and numerical results available in the mathematical and engineering literature, regarding the accuracy of these methods. (The numerical procedures for the solution of the linear and non linear related systems are briefly reviewed in 作者: Isthmus 時間: 2025-3-29 09:04 作者: 窒息 時間: 2025-3-29 12:58
