標(biāo)題: Titlebook: Orexin and Sleep; Molecular, Functiona Takeshi Sakurai,S.R. Pandi-Perumal,Jaime M. Monti Book 2015 Springer International Publishing Switze [打印本頁(yè)] 作者: papyrus 時(shí)間: 2025-3-21 16:03
書(shū)目名稱(chēng)Orexin and Sleep影響因子(影響力)
書(shū)目名稱(chēng)Orexin and Sleep影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)Orexin and Sleep網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱(chēng)Orexin and Sleep網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱(chēng)Orexin and Sleep被引頻次
書(shū)目名稱(chēng)Orexin and Sleep被引頻次學(xué)科排名
書(shū)目名稱(chēng)Orexin and Sleep年度引用
書(shū)目名稱(chēng)Orexin and Sleep年度引用學(xué)科排名
書(shū)目名稱(chēng)Orexin and Sleep讀者反饋
書(shū)目名稱(chēng)Orexin and Sleep讀者反饋學(xué)科排名
作者: 閃光你我 時(shí)間: 2025-3-21 20:25
Oscar Arias-Carrión,Andrea Herrera-Solís,Alwin Poot-Aké,Ramsés Jiménez-Moreno,Eric Murillo-Rodríguezls ist die Gefahr gro?, mit dem Lehrer ?rger zu bekommen. Auch Kunden sagen nicht sofort, wenn sie etwas nicht verstehen oder sie etwas nicht interessiert. Viele sind einfach h?flich. Und so redet der Verk?ufer munter weiter und glaubt, gleich den Auftrag in der Tasche zu haben, und ist umso verwund作者: 苦笑 時(shí)間: 2025-3-22 03:55 作者: 編輯才信任 時(shí)間: 2025-3-22 06:37 作者: Fraudulent 時(shí)間: 2025-3-22 11:13
Input and Output Systems of Orexin Neurons,n the brain. Two types of orexin receptors, OX1 and OX2, are expressed in various brain areas, including neurons controlling fundamental functions in the brain, such as sleep/wake behavior, feeding and drinking, homeostatic regulation, neuroendocrine and autonomic responses. In this chapter, we summ作者: HAVOC 時(shí)間: 2025-3-22 16:34 作者: glamor 時(shí)間: 2025-3-22 19:57
Orexin Receptor Functions in the Ascending Arousal System,c orexin (hypocretin)-synthesizing neurons innervate these regions, including monoaminergic and cholinergic structures, where orexin receptors are strongly expressed, naturally suggested involvement of orexin peptides in regulating arousal. This general idea has been supported by multiple, compellin作者: 口音在加重 時(shí)間: 2025-3-22 21:22 作者: ESO 時(shí)間: 2025-3-23 05:00 作者: NEG 時(shí)間: 2025-3-23 08:47 作者: 卜聞 時(shí)間: 2025-3-23 12:28 作者: DEAF 時(shí)間: 2025-3-23 17:20 作者: 辮子帶來(lái)幫助 時(shí)間: 2025-3-23 18:39
Symptomatic Narcolepsy or Hypersomnia, with and Without Orexin (Hypocretin) Deficiency,y as cases that meet the International Sleep Disorders Narcolepsy Criteria, which are also associated with a significant underlying neurological disorder that accounts for excessive daytime sleepiness (EDS) and temporal associations. By 2005, we have counted 116 symptomatic cases of narcolepsy repor作者: glans-penis 時(shí)間: 2025-3-24 00:57
Narcolepsy and Idiopathic Hypersomnia,nes (i.e., hypocretin receptor and peptide genes) in animals in 1999 and the subsequent discovery in 2000, of hypocretin ligand deficiency (i.e., loss of hypocretin neurons in the brain) in idiopathic cases of human narcolepsy-cataplexy. The hypocretin deficiency can be clinically detected by cerebr作者: 留戀 時(shí)間: 2025-3-24 05:25 作者: 古董 時(shí)間: 2025-3-24 08:55 作者: 剝削 時(shí)間: 2025-3-24 11:54
A New Class of Hypnotic Compounds for the Treatment of Insomnia: The Dual Orexin Receptor Antagonisor insomnia, including allosteric modulators of the gamma-aminobutyric acid type A receptor (GABAA), such as zolpidem (Ambien.) and eszopiclone (Lunesta.), have undesirable effects that limit their tolerability and utility. The dual orexin receptor antagonists (DORAs), possessing novel mechanisms of作者: 財(cái)產(chǎn) 時(shí)間: 2025-3-24 15:45
Pathway and Effect of Intranasal Orexin, of the link between orexin-A deficiency and the disorder narcolepsy, effects of orexin on sleep and wakefulness are of particular interest for clinical purposes. Indeed, the transfer of results of animal studies to study protocols with humans is problematic. The utilized methods used in animals are作者: 廣告 時(shí)間: 2025-3-24 21:42
Hypocretin (Orexin) Cell Transplantation as a New Therapeutic Approach in Narcolepsy,bed nocturnal sleep as well as cataplexy. It is known that this disease is caused by deficiency of the neurotransmission system of the peptide named hypocretin (HCRT), also cited as orexin (OX). The ablation of HCRT/OX or HCRT/OX receptors in animal models has supported the understanding of the huma作者: 推延 時(shí)間: 2025-3-25 01:57 作者: byline 時(shí)間: 2025-3-25 05:32 作者: Dislocation 時(shí)間: 2025-3-25 09:59
The Hypocretin Story,ypothesis ended up converging with a reverse pharmacology approach followed by Yanagisawa and colleagues, which is described in detail in other chapters. With the hypocretin story in the background, I also describe here the first implementation of optogenetic methods in a freely moving animal, which has led to a revolution in systems neuroscience.作者: 殺死 時(shí)間: 2025-3-25 12:32
Orexin Receptor Functions in the Ascending Arousal System,cholinergic targets play key roles in this disorder. In this review, we discuss the cellular actions of orexin at these targets and the roles played by each receptor based on results from constitutive receptor knockout mice. We then consider the implications of these actions for understanding the role played by orexin in arousal and narcolepsy.作者: 易怒 時(shí)間: 2025-3-25 17:53 作者: 暫時(shí)休息 時(shí)間: 2025-3-25 20:45 作者: largesse 時(shí)間: 2025-3-26 04:08 作者: congenial 時(shí)間: 2025-3-26 05:36 作者: RECUR 時(shí)間: 2025-3-26 08:48
Optogenetic Dissection of Sleep-Wake Circuits in the Brain, shown to promote REM sleep. The projections from the lateral hypothalamus are diverse, as are it’s functions in other behaviours such as energy homeostasis and feeding. Future work is now needed to determine which part of this circuitry is required for regulation of the sleep-wake state and ultimately how consciousness is controlled.作者: 喚醒 時(shí)間: 2025-3-26 15:21
Hypocretin/Orexin Pathology in Human Narcolepsy with and Without Cataplexy, of Hcrt cells compared to normal, with maximal cell loss in the posterior hypothalamus. A better understanding of the pattern of damage to Hcrt containing somas and axons and of the gliosis occurring in narcolepsy should clarify the nature of the pathological process responsible for this disorder.作者: Morphine 時(shí)間: 2025-3-26 19:08 作者: 有說(shuō)服力 時(shí)間: 2025-3-26 21:35
Orexin Induced Modulation of REM Sleep and Its Loss Associated Patho-Physiological Changes Are Medi in health and diseases. Based on the findings/reports from this lab and that of others, we conclude that orexin-induced modulation (loss) of REMS and associated pathophysiological changes are mediated to a large extent at least by influencing the noradrenalin (NA)-ergic neurons in the LC, which possesses REM-OFF neurons.作者: 手術(shù)刀 時(shí)間: 2025-3-27 03:23
History of Orexin Research,iyama et al. in Eur J Neurosci 20:3054–3062, .; Mieda et al. in J Neurosci 24:10493–10501, .; Sakurai et al. in Neuron 46:297–308, .; Yoshida et al. in J Comp Neurol 494:845–861, .; Harris et al. in Nature 437:556–559, .; Narita et al. in J Neurosci 26:398–405, .). Subsequent studies suggested that 作者: 留戀 時(shí)間: 2025-3-27 07:31 作者: interference 時(shí)間: 2025-3-27 11:50
Orexin, Alcohol and Sleep Homeostasis,lamus is involved in spontaneous as well as recovery sleep after prolonged wakefulness. Our second group of experiments suggests that alcohol increases extracellular levels of AD in the orexin-rich perifornical hypothalamus, increased AD activates A1 receptors on orexinergic neurons and inhibits the作者: Explosive 時(shí)間: 2025-3-27 15:29 作者: febrile 時(shí)間: 2025-3-27 20:49
Symptomatic Narcolepsy or Hypersomnia, with and Without Orexin (Hypocretin) Deficiency, brain tumors, head trauma, and immune-mediated neurological conditions, such as neuromyelitis optica (NMO), and EDS in these cases is sometimes reversible with an improvement of the causative neurological disorder and an improvement of orexin status. It is also noted that some symptomatic EDS cases作者: Jacket 時(shí)間: 2025-3-28 00:10 作者: Urologist 時(shí)間: 2025-3-28 05:06
Orexin and Circadian Influences in Sleep and Psychiatric Disorders: A Review of Experimental and Coen orexinergic, monoaminergic, circadian oscillators, and sleep-wake neural circuitry. Our main aim is to understand how these physiological systems interact and how alteration in any of these factors can contribute to the behaviours commonly observed in depressive patients. Further, we examine how 作者: 套索 時(shí)間: 2025-3-28 09:25 作者: 攝取 時(shí)間: 2025-3-28 11:55 作者: inflate 時(shí)間: 2025-3-28 15:41 作者: 用手捏 時(shí)間: 2025-3-28 21:03
Birendra Nath Mallick,Mudasir Ahmad Khanday,Abhishek Singh作者: Agility 時(shí)間: 2025-3-29 01:39 作者: Fatten 時(shí)間: 2025-3-29 04:25 作者: 人造 時(shí)間: 2025-3-29 07:48 作者: concise 時(shí)間: 2025-3-29 13:25
Sara Lena Weinhold,Robert G?der,Paul Christian Baier作者: Folklore 時(shí)間: 2025-3-29 16:57
and highly readable summary of the basic concepts in orexin biology and pharmacology along with clinical applications in sleep medicine in general, and narcolepsy in particular..978-3-319-35220-6978-3-319-23078-8作者: 蘑菇 時(shí)間: 2025-3-29 23:23
Modulation of Thalamocortical Pathways by Orexins,Modern research on sleep-wake cycle and arousal is based on the ascending reticular arousal system (ARAS), described in the 1940s by Moruzzi and Magoun. This system is located in the upper brainstem and separates in two branches, one innervating the thalamus and the other the orexin and cholinergic nuclei of the basal forebrain.作者: Ingest 時(shí)間: 2025-3-30 03:57 作者: 老人病學(xué) 時(shí)間: 2025-3-30 04:21 作者: MULTI 時(shí)間: 2025-3-30 09:00
978-3-319-35220-6Springer International Publishing Switzerland 2015作者: 小步舞 時(shí)間: 2025-3-30 15:39
Takeshi Sakurai,S.R. Pandi-Perumal,Jaime M. MontiProvides comprehensive overview of the field, in-depth coverage of basic and clinical research.Presents established theories as well as the most recent developments in neurology, psychiatry, neuroendo作者: modifier 時(shí)間: 2025-3-30 19:52
The Physiology of Micturition. Bladder function can be subdivided into two interrelated yet distinct phases, . and its controlled . at an appropriate time and place. Most contemporary knowledge is based on studies with experimental animals. Although it can be difficult and is often misleading to relate findings from animal mode作者: vertebrate 時(shí)間: 2025-3-30 23:07 作者: 耕種 時(shí)間: 2025-3-31 02:12
Polar ice sheets: Introduction,e ... We briefly discuss the wavelength selection dilemma. We say a few words on the transition to the restabilization of the planar front at high growth speeds. This restabilization is likely preceeded by a chaotic regime.作者: 罵人有污點(diǎn) 時(shí)間: 2025-3-31 08:57
Creative Co-production: The Adaption of an Open Innovation Model in Creative Industriesimplementation of co-production in creative industries based on three components: co-creation environment, network coordination, and experiential communication. The proposed framework is sufficiently general yet grounded in the phenomenon to guide future research and development.作者: cognizant 時(shí)間: 2025-3-31 11:45 作者: 虛假 時(shí)間: 2025-3-31 13:27 作者: albuminuria 時(shí)間: 2025-3-31 19:26
Florian Rehm,Markus Rudolfal and each has a role for specific drugs. However, no one method is a practical dose calculation strategy for many or all drugs. Neither body size nor fixed dosing alone can be used for currently available drugs. Conclusion: Dosing strategies for anticancer drugs should be individualized according 作者: Encephalitis 時(shí)間: 2025-3-31 23:02 作者: 興奮過(guò)度 時(shí)間: 2025-4-1 04:31 作者: indices 時(shí)間: 2025-4-1 08:20 作者: 可轉(zhuǎn)變 時(shí)間: 2025-4-1 13:30
Verbalization of the term-concept , in Ukrainian political and legal discourseня досл?джуваних одиниць, а й процеси моделювання цих значень в дискурс? ? вплив цих процес?в на формування державно? пол?тики ?вропейсько? ?нтеграц?? та ?? сприйняття сусп?льством. Значення терм?ноконцепт?в класиф?ковано за тематичними групами, на основ? яких узагальнено дискурсивн? тенденц?? ?вро?нтеграц?? Укра?ни.作者: grieve 時(shí)間: 2025-4-1 17:43
Textbook 2016vexity, and optimization..Most of the problems presented here are non-standard and some require broad knowledge of different mathematical subjects in order to be solved. The author provides some hints and (partial) answers and also puts these carefully chosen exercises into context, presents informa
