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標(biāo)題: Titlebook: Optimal Control for Mathematical Models of Cancer Therapies; An Application of Ge Heinz Sch?ttler,Urszula Ledzewicz Book 2015 Springer Scie [打印本頁]

作者: 日月等    時間: 2025-3-21 19:41
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Optimal Control for Problems with a Quadratic Cost Functional on the Therapeutic Agents,trol in the objective is taken as a positive definite quadratic function. The mathematical advantages of such a formulation are obvious: the Hamiltonian . for the optimal control problem becomes strictly convex in the control . and thus has a unique minimizer, albeit only in the state-multiplier spa
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Optimal Control of Mathematical Models for Antiangiogenic Treatments,herapeutically sensitive cells to heterogeneous structures of cell populations with varying sensitivities or even resistance. From an optimal control point of view, optimal treatment schedules change from bang-bang solutions with upfront dosing (that correspond to classical MTD approaches in medicin
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Concluding Remarks,ents. In the administration of cancer treatments, these questions are still far from being answered conclusively. In this text, we have explored what can be said about this topic from an analysis of minimally parameterized models described by ordinary differential equations using an optimal control
作者: 機構(gòu)    時間: 2025-3-23 09:04
Heinz Sch?ttler,Urszula Ledzewicz it describes the structure and evaluation of the learner model implemented within VIS (the Vygotskian Instructional System). This software explores the way that Vygotsky’s Zone of Proximal Development can be used in the design of learner models. This theoretical foundation requires the system to ad
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Heinz Sch?ttler,Urszula Ledzewicz it describes the structure and evaluation of the learner model implemented within VIS (the Vygotskian Instructional System). This software explores the way that Vygotsky’s Zone of Proximal Development can be used in the design of learner models. This theoretical foundation requires the system to ad
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978-1-4939-4279-4Springer Science+Business Media, LLC 2015
作者: 想象    時間: 2025-3-24 12:32
Optimal Control for Mathematical Models of Cancer Therapies978-1-4939-2972-6Series ISSN 0939-6047 Series E-ISSN 2196-9973
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Interdisciplinary Applied Mathematicshttp://image.papertrans.cn/o/image/702818.jpg
作者: Goblet-Cells    時間: 2025-3-24 23:20
https://doi.org/10.1007/978-1-4939-2972-6Optimal control; anti-angiogenic treatment; geometric optimal control; mathematical models; mathematical
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Cancer and Tumor Development: Biomedical Background,tails. Yet, it is precisely this highly simplified overall understanding that has motivated much of the historical developments of cancer research and it still defines most current activities in the “search for a cure.”
作者: 圣人    時間: 2025-3-25 22:12
Optimal Control of Mathematical Models for Antiangiogenic Treatments,e) to administrations that also include singular controls (which correspond to time-varying dosing schedules at less than maximum rates) as heterogeneity of the tumor population becomes more prevalent. In this chapter, we begin to analyze mathematical models that also take into account a tumor’s microenvironment.
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作者: 符合規(guī)定    時間: 2025-3-26 04:53
Book 2015ematical models for both classical and novel cancer treatments are presented as optimal control problems with the goal of constructing optimal protocols. The power of geometric methods is illustrated with fully worked out complete global solutions to these mathematically challenging problems. Elabor
作者: Suppository    時間: 2025-3-26 08:48
0939-6047 ence and engineering, particularly biomathematics and more mathematical aspects of biomedical engineering, would find this book particularly useful..978-1-4939-4279-4978-1-4939-2972-6Series ISSN 0939-6047 Series E-ISSN 2196-9973
作者: Oversee    時間: 2025-3-26 15:49
Heinz Sch?ttler,Urszula Ledzewiczthe approach adopted by VIS promotes the construction of productive interactions with the majority of learners, across a range of abilities. The learner model within VIS is in effect an operational definition of the ZPD of each learner who interacts with the system.
作者: sperse    時間: 2025-3-26 20:15
Heinz Sch?ttler,Urszula Ledzewiczthe approach adopted by VIS promotes the construction of productive interactions with the majority of learners, across a range of abilities. The learner model within VIS is in effect an operational definition of the ZPD of each learner who interacts with the system.
作者: 枯燥    時間: 2025-3-27 00:08
Heinz Sch?ttler,Urszula Ledzewiczthe approach adopted by VIS promotes the construction of productive interactions with the majority of learners, across a range of abilities. The learner model within VIS is in effect an operational definition of the ZPD of each learner who interacts with the system.
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作者: OPINE    時間: 2025-3-27 07:20
Heinz Sch?ttler,Urszula Ledzewiczthe approach adopted by VIS promotes the construction of productive interactions with the majority of learners, across a range of abilities. The learner model within VIS is in effect an operational definition of the ZPD of each learner who interacts with the system.
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Cancer Chemotherapy for Heterogeneous Tumor Cell Populations and Drug Resistance,subpopulations of cells that show widely varying sensitivities toward the actions of a particular chemotherapeutic agent [., .]. Coupled with the fact that growing tumors also exhibit considerable evolutionary ability to enhance cell survival in an environment that is becoming hostile, this leads to
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