標(biāo)題: Titlebook: Oncogenes; An Introduction to t Kathy B. Burck,Edison T. Liu,James W. Larrick Book 1988 Springer-Verlag New York Inc. 1988 Chromosom.DNA.ca [打印本頁] 作者: ABS 時間: 2025-3-21 16:33
書目名稱Oncogenes影響因子(影響力)
書目名稱Oncogenes影響因子(影響力)學(xué)科排名
書目名稱Oncogenes網(wǎng)絡(luò)公開度
書目名稱Oncogenes網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Oncogenes被引頻次
書目名稱Oncogenes被引頻次學(xué)科排名
書目名稱Oncogenes年度引用
書目名稱Oncogenes年度引用學(xué)科排名
書目名稱Oncogenes讀者反饋
書目名稱Oncogenes讀者反饋學(xué)科排名
作者: 勉強(qiáng) 時間: 2025-3-21 22:12 作者: insightful 時間: 2025-3-22 03:02 作者: 錯 時間: 2025-3-22 08:01
http://image.papertrans.cn/o/image/701355.jpg作者: Ancillary 時間: 2025-3-22 09:46 作者: alleviate 時間: 2025-3-22 15:00 作者: 符合你規(guī)定 時間: 2025-3-22 20:49 作者: 出來 時間: 2025-3-23 01:02
Viruses and Oncogenes,th animal and human neoplasia. DNA tumor viruses associated with cancer on epidemiological grounds include papilloma viruses and urogenital cancer, herpes viruses and Burkitt’s lymphoma and nasopharyngeal carcinoma, and hepatitis viruses and liver cancer. No biochemically defined oncogenes have yet 作者: Wernickes-area 時間: 2025-3-23 04:00
Cellular Proto-oncogenes,lignant cells were homologous to retroviral oncogenes was made in 1976. Cellular proto-oncogenes have exon and intron structures typical of eukaryotic genes. Some exon sequences are well conserved among vertebrate and invertebrate species. The retroviral life cycle suggests a mechanism whereby cellu作者: Adulate 時間: 2025-3-23 07:39
Oncogenes and Human Cancers,h a variety of mechanisms, have been associated with human cancers. Perturbations in the structure or expression of certain proto-oncogenes appear to be the general means by which this activation occurs..Examples of structural changes are seen in single amino acid substitutions in the . family of ge作者: 薄膜 時間: 2025-3-23 12:28
, and Related Protein Kinases,inases comprise a family of regulatory enzymes involved in the control of cellular growth and differentiation. The family includes members closely related to .: (1) the . oncogenes that are implicated in the translocation characteristic of chronic myelogenous leukemia, (2) receptors for growth facto作者: resistant 時間: 2025-3-23 15:22 作者: 低三下四之人 時間: 2025-3-23 20:14
, Family of Oncogenes,oncogene was the first to be directly implicated in human neoplasia. An H-. gene from a bladder carcinoma cell line was isolated and characterized by its ability to transform the murine cell line NIH 3T3..Single-base-pair differences at specific codons distinguish normal pvoto-. genes from their onc作者: 掙扎 時間: 2025-3-24 00:13 作者: Creditee 時間: 2025-3-24 05:20
Additional Oncogenes, previous chapters we described functional groups of these oncogenes. In this chapter we describe several oncogenes that are as yet unclassified or are novel in their apparent mechanisms (Table 11.1). It is anticipated that eventually the function of these genes will be discovered and their role in 作者: 誘騙 時間: 2025-3-24 09:14
Transgenic Mice: Direct In Vivo Assay for Oncogenes,uman tissue and human cell lines give circumstantial support to the hypothesis. However, until recently it was not possible to test these genes directly in vivo independently of their association with acute retroviruses. The development of methods to introduce genes into the germ lines of mice and o作者: 碎石 時間: 2025-3-24 11:20
Potential Diagnostic Uses of Oncogenes,l cancers. With chronic myelogenous leukemia, for example, the . oncogene is translocated to chromosome 22 in the vicinity of the . gene. A cancer-specific fusion protein qualitatively different from parent cell proteins is thus produced and is an ideal cancer marker. Mutant ras genes have now been 作者: 尖酸一點(diǎn) 時間: 2025-3-24 18:10 作者: 陳舊 時間: 2025-3-24 21:25 作者: 有發(fā)明天才 時間: 2025-3-25 02:28
Kathy B. Burck M.D., Ph.D.,Edison T. Liu M.D.,James W. Larrick M.D., Ph.D.glich und sinnvoll ist. Bezogen auf Innovationen für Material- und Informationsflu?prozesse ist die empirische Untersuchung des Methodeneinsatzes und der Rahmenbedingungen an mehrere Problemkreise gebunden.. Die Analyse bestehender Systeme und ihrer Ver?nderungsm?glichkeiten erfolgt innerhalb eines 作者: 組裝 時間: 2025-3-25 04:43
Kathy B. Burck M.D., Ph.D.,Edison T. Liu M.D.,James W. Larrick M.D., Ph.D. realisieren und Qualit?tsvorsprünge durch eine konsequente Ausrichtung auf den Kundennutzen zu erzielen. Rationalisierungsm?glichkeiten k?nnen weder durch die isolierte Optimierung von Prim?rprozessen der Leistungserstellung noch durch eine punktuelle Verbesserung von Sekund?rprozessen umfassend au作者: 可觸知 時間: 2025-3-25 08:46 作者: pellagra 時間: 2025-3-25 12:36
Kathy B. Burck M.D., Ph.D.,Edison T. Liu M.D.,James W. Larrick M.D., Ph.D. realisieren und Qualit?tsvorsprünge durch eine konsequente Ausrichtung auf den Kundennutzen zu erzielen. Rationalisierungsm?glichkeiten k?nnen weder durch die isolierte Optimierung von Prim?rprozessen der Leistungserstellung noch durch eine punktuelle Verbesserung von Sekund?rprozessen umfassend au作者: 考得 時間: 2025-3-25 16:14
Kathy B. Burck M.D., Ph.D.,Edison T. Liu M.D.,James W. Larrick M.D., Ph.D.anwendung oder den Mi?brauch von Werten: bei sich selbst, in der Familie, der sozialen Gruppe, in Organisationen und Institutionen oder in aller Welt. . z. B. kann man in Schulklasse, Gruppe, Gesellschaft oder auch in der Europ?ischen Gemeinschaft üben oder vernachl?ssigen — jeweils auf verschiedene作者: 好開玩笑 時間: 2025-3-25 20:18
Kathy B. Burck M.D., Ph.D.,Edison T. Liu M.D.,James W. Larrick M.D., Ph.D.cheren wie unsicheren Komponenten, in Wandlungen und überg?ngen und ihren tertia comparationis analysiert werden. In diesem Zusammenhang l??t sich auch das oft als erschreckend ausgemalte Tempo der Ver?nderungen mit ihren z. T. jahrhundertealten Vorl?ufern etwas ruhiger und gelassener betrachten. L?作者: 繼而發(fā)生 時間: 2025-3-26 01:27 作者: 希望 時間: 2025-3-26 04:35 作者: 走調(diào) 時間: 2025-3-26 09:30 作者: Canary 時間: 2025-3-26 14:31
Kathy B. Burck M.D., Ph.D.,Edison T. Liu M.D.,James W. Larrick M.D., Ph.D. verstehe.,Objektiver wie subjektiver Leib stehen hier in Wechselwirkung und sind so wiederum einander gleich: der objektive Leib meint nur, indem er sein Meinen deutet, er meint nur, insofern der subjektive Leib als Objekt sein Meinen deutet, und der subjektive Leib als Subjekt deutet nur, insofern作者: abduction 時間: 2025-3-26 19:01
Kathy B. Burck M.D., Ph.D.,Edison T. Liu M.D.,James W. Larrick M.D., Ph.D. Sozialwissenschaften in eine Reihe von Einzelwissenschaften besonders seit Mitte dieses Jahrhunderts ist parallel zur Ausbildung der gro?en Mehrzahl von Soziologen für au?eruniversit?re T?tigkeitsfelder eine Parzellierung der Soziologie in anwendungsbezogene Teilbereiche zu beobachten. Es scheint, 作者: hankering 時間: 2025-3-26 22:25 作者: 共和國 時間: 2025-3-27 04:30 作者: decipher 時間: 2025-3-27 05:24 作者: 詩集 時間: 2025-3-27 12:45
Institute, they were largely ignored for several decades. Witness his eventual recognition for a Nobel Prize, but not until 1966-setting an all time record for latency, and testimony to one more advantage of longevity. In the 1950s, another Rockefeller Nobelist, Wendell Stanley, spearheaded a campai作者: Colonnade 時間: 2025-3-27 14:07
Introduction, central concept of proto-oncogenes and oncogenes: normal cellular genes (proto-oncogenes) controlling growth, development, and differentiation that somehow become misdirected (i.e. converted to oncogenes) in the neoplastic cancer cell.作者: GULF 時間: 2025-3-27 18:37 作者: OASIS 時間: 2025-3-27 22:29
Oncogene Paradigm: Contribution to a Fundamental Understanding of Malignancy,A. Because cancer is characterized by loss of this normal control, we can at least begin to define and understand malignancy in molecular terms. The oncogene concept provides us with a reasonable molecular “handle” with which to deal with cancer.作者: novelty 時間: 2025-3-28 04:52 作者: 猛然一拉 時間: 2025-3-28 07:31
Kathy B. Burck M.D., Ph.D.,Edison T. Liu M.D.,James W. Larrick M.D., Ph.D.作者: Cocker 時間: 2025-3-28 14:14 作者: 僵硬 時間: 2025-3-28 15:08
Assays: Tools of the New Biology,pertinent fragments that include DNA sequences of interest. This is accomplished by restriction endonuclease digestion, agarose gel electrophoresis, and Southern blot hybridization. DNA fragments can be isolated and expanded for more detailed studies by employing procedures whereby individual fragme作者: follicular-unit 時間: 2025-3-28 20:32
Viruses and Oncogenes,to subserve similar functions..The RNA tumor viruses were the first infectious agents unequivocally associated with neoplasia. A large number of such viruses have been isolated from chickens, rodents, cats, and monkeys. Many transduce one or two oncogene sequences necessary and sufficient for effici作者: 手工藝品 時間: 2025-3-29 00:03
Cellular Proto-oncogenes,rentiation. Aberrant growth and development are characteristic of cancer, and the hypothesis that abnormal “activated” oncogenes contribute to the neoplastic state is therefore attractive. Changes activating normal proto-oncogenes to transforming oncogenes could occur at the DNA, RNA, or protein lev作者: 刻苦讀書 時間: 2025-3-29 06:20
Oncogenes and Human Cancers,ase of translocations involving c-. seen in Burkitt’s lymphomas, or due to amplification which augments expression by increasing the gene copy number. Amplifications of N-. in neuroblastoma, and . in human breast cancer have been correlated with a more advanced stage and a poorer prognosis..Recently作者: 證實(shí) 時間: 2025-3-29 10:06
, and Related Protein Kinases, region encoding a tyrosine near the carboxy terminus of the protein. This alteration, also found in many of the growth factor receptor oncogenes, causes these proteins to function abnormally. Although several substrates of the tyrosine kinases have been found, those critical for the initiation and 作者: CAB 時間: 2025-3-29 11:42
Growth Factors and Receptors,e . gene encodes a product similar to the macrophage colony-stimulating factor-1 receptor; the . oncogene product shows some homology with the insulin receptor. In these instances the normal cellular genes have been rendered transforming by point mutations and/or deletions. Proepidermal growth facto作者: Defiance 時間: 2025-3-29 18:05
, Family of Oncogenes,l p21 has GTPase activity that converts the protein from an active to an inactive form. Mutant p21s may have reduced or ineffectual GTPase activity leading to constitutive activation of the protein. Activated protein may transduce a signal(s) important for cell growth; thus constitutive activation m作者: 鞭打 時間: 2025-3-29 19:56
, and Other Nuclear Oncogenes,lly associated. The . protein is known to have a nuclear location and may be associated with small nuclear ribonuclear proteins. Other . genes include N-. from neuroblastoma, L-. from small-cell carcinoma of the lung, and R-. from rhabdomyosarcoma..The . gene first was characterized as an avian retr作者: 忍受 時間: 2025-3-30 03:24
Potential Diagnostic Uses of Oncogenes,ted with stage and pathogenesis of cancers of all types. The development of specific antibodies and probes will facilitate this work, and the use of novel DNA amplification techniques and the cell sorter to study populations of cells will permit cancer to be diagnosed earlier and followed more close作者: Truculent 時間: 2025-3-30 04:44
Potential Therapeutic Applications of Oncogenes,c nucleic acid sequences might be targeted by antisense oligonucleotides of DNA or RNA and by nucleotide antimetabolites such as dideoxy- or methylphosphonate-modified nucleotides..Another approach is to vaccinate against tumors or their known etiological agents. In particular, vaccines against tumo作者: Flu表流動 時間: 2025-3-30 11:58 作者: 有花 時間: 2025-3-30 14:12
Kathy B. Burck M.D., Ph.D.,Edison T. Liu M.D.,James W. Larrick M.D., Ph.D.itischen Erfolgsfaktoren im Wettbewerb ausgerichtet werden.. Der Faktor Zeit ist für die Gestaltung der Ressourcenausstattung von zentraler und noch steigender Bedeutung.. Die Geschwindigkeit, mit der Rationalisierungspotentiale erkannt, erschlossen und in wettbewerbsrelevante Erfolgsfaktoren umgese作者: Brain-Imaging 時間: 2025-3-30 20:01 作者: carbohydrate 時間: 2025-3-30 23:20
