標(biāo)題: Titlebook: Oncogene-Induced Senescence; Methods and Protocol Mikhail A. Nikiforov Book 2017 Springer Science+Business Media New York 2017 Senescent ce [打印本頁] 作者: 喜悅 時間: 2025-3-21 17:17
書目名稱Oncogene-Induced Senescence影響因子(影響力)
作者: Gratuitous 時間: 2025-3-21 23:29
RT-qPCR Detection of Senescence-Associated Circular RNAs, circRNAs in senescence require distinct molecular approaches. In this chapter, we describe a method for the detection and measurement of circRNAs in senescent cells using specialized reverse transcription (RT) followed by real-time quantitative (q)PCR analysis.作者: 豐富 時間: 2025-3-22 03:20 作者: 笨拙的我 時間: 2025-3-22 06:57 作者: flourish 時間: 2025-3-22 09:12 作者: 遵循的規(guī)范 時間: 2025-3-22 14:49
Detection of Senescence Markers During Mammalian Embryonic Development,in the developing embryo. This chapter describes the methods for identifying cellular senescence in the embryo, detailing protocols for the detection of SAβ-gal activity in both sections and at the whole mount level, and immunohistochemistry protocols for the detection of additional biomarkers of senescence.作者: Inscrutable 時間: 2025-3-22 20:34
Metabolic Changes Investigated by Proton NMR Spectroscopy in Cells Undergoing Oncogene-Induced Senertant information on the underlying molecular pathways can be obtained. Here, we describe how to investigate metabolic changes in a model of oncogene-induced senescence. The water-soluble metabolites are isolated by a chloroform-methanol treatment and subsequently analyzed by NMR spectroscopy.作者: Wordlist 時間: 2025-3-22 21:18 作者: 改變立場 時間: 2025-3-23 03:58
Book 2017eling of this complex cellular program of oncogene-induced senescence. The book encompasses protocols for studying this multi-step program in human specimens and a variety of experimental models including cultured mammalian cells, laboratory mice, and?.Drosophila melanogaster., as well as offering a作者: Prostaglandins 時間: 2025-3-23 07:33 作者: 揉雜 時間: 2025-3-23 09:59
Cellular Model of p21-Induced Senescence,with the lac repressor and exogenous p21 under the control of a lac repressor regulated promoter. The senescent phenotype is induced in these cells by isopropyl-β-.-thiogalactopyranoside (IPTG)-inducible expression of senescence-associated cell cycle inhibitor p21..作者: Clinch 時間: 2025-3-23 15:44
Sudan Black B, The Specific Histochemical Stain for Lipofuscin: A Novel Method to Detect Senescent t senescent cells in any material, irrespective of its preparation. This provides unique advantages not only in understanding physiological processes and the pathophysiology of various diseases but also in estimating the response to therapeutic interventions.作者: Mumble 時間: 2025-3-23 18:56 作者: Nmda-Receptor 時間: 2025-3-24 01:56 作者: Gorilla 時間: 2025-3-24 04:34 作者: 是突襲 時間: 2025-3-24 07:36 作者: 初次登臺 時間: 2025-3-24 13:43 作者: 不可知論 時間: 2025-3-24 15:57
Mohammad Althubiti,Salvador Macipour favorite. Because of its deep functional and technological integration, it is as well a good choice for universities teaching ERP systems. Reading This Book Theprimary purpose of this book is to provide you with a good knowledge of thestandard application concept and functionality, which is requ作者: Pcos971 時間: 2025-3-24 19:30
Claudia Gey,Karsten Seegerstützen sie sich immer h?ufiger auf Informations- und Kommunikationssysteme (IuK). Neueren - tersuchungen zufolge arbeiteten im Jahre 2005 fast 54 % der deutschen Besch?ftigten mindestens ein Viertel ihrer Arbeitszeit am Computer. Ca. 40 % nutzten dabei E-Mail oder das Internet für ihre Arbeit, fast作者: discord 時間: 2025-3-25 01:27 作者: GULLY 時間: 2025-3-25 06:29
Andrew Joselow,Darren Lynn,Tamara Terzian,Neil F. Boxystemen ausgebildet. Im Fokus der Ausbildung steht die Vermittlung eines - fassenden, universalen Wissens sowie Grundfertigkeiten in der Anwendung zur CAx-Technologie, ohne eine Spezialisierung auf nur ein einziges System. Dazu bearbeiten die Studenten auf ihrem Weg zum Diplom eine gro?e Anzahl von 作者: investigate 時間: 2025-3-25 09:03 作者: 消耗 時間: 2025-3-25 14:36 作者: 黃油沒有 時間: 2025-3-25 16:13
The Immortal Senescence,scence (OIS)). OIS is a fail-safe mechanism used by the cells to prevent uncontrolled tumor growth, and, as such, it is considered as the first barrier against cancer. In order to progress, tumor cells thus need to first overcome the senescent phenotype. Despite the increasing attention gained by OI作者: 博識 時間: 2025-3-25 21:43
Senescence Phenotypes Induced by Ras in Primary Cells,induce senescence, including telomere shortening and oncogene activation. The phenotypes elicited by pro-senescent signals can be heterogeneous depending on the stimulus and the cell type affected. To date, there is not a definitive marker that can ubiquitously and specifically mark all senescent ce作者: 無辜 時間: 2025-3-26 02:43 作者: 審問,審訊 時間: 2025-3-26 06:25 作者: ADORN 時間: 2025-3-26 11:01
Genome-Wide miRNA Screening for Genes Bypassing Oncogene-Induced Senescence,owerful in associating genes with certain phenotypes or signal transduction pathways and thus are valuable tools to define gene function. Here we describe a genome-wide miRNA screening strategy to identify miRNAs that are required to bypass oncogene-induced senescence.作者: insecticide 時間: 2025-3-26 16:23
Detection of Dysfunctional Telomeres in Oncogene-Induced Senescence,t to culture stresses, such as human dermal fibroblasts, this oncogene-induced senescence (OIS) is a result of a DNA damage response (DDR) that is activated due to the formation of DNA lesions at both non-telomeric and telomeric DNA sequences. DNA lesions can be visualized as DDR foci by immunofluor作者: 概觀 時間: 2025-3-26 20:30
RT-qPCR Detection of Senescence-Associated Circular RNAs,roliferation and enter a state of long-term growth arrest named senescence. The senescent process has been implicated in a variety of age-related diseases and also in the pathogenesis of cancer. Senescence is characterized by distinct changes in the types and levels of coding RNAs (mRNAs) as well as作者: 狂亂 時間: 2025-3-26 23:59
Autophagy Detection During Oncogene-Induced Senescence Using Fluorescence Microscopy, likely determines the quality of the phenotype (Pérez-Mancera et al., Nat Rev Cancer 14:547–558, 2014). Autophagy, a cellular degradation process, has been proposed to be one of these senescence effectors, although its functional relevance seems highly context dependent (Hoare et al., Semin Cancer 作者: Host142 時間: 2025-3-27 02:40 作者: Conflagration 時間: 2025-3-27 09:17
Sudan Black B, The Specific Histochemical Stain for Lipofuscin: A Novel Method to Detect Senescent als. Lipofuscin is related to many ageing processes. It is also known to accumulate in senescent cells. We recently proved that lipofuscin detection, when applying the SBB staining, is highly specific for the visualization of senescent cells. Here, we present in detail this SBB method that can detec作者: 死亡率 時間: 2025-3-27 13:15 作者: innovation 時間: 2025-3-27 15:38
Detection of Reactive Oxygen Species in Cells Undergoing Oncogene-Induced Senescence, radical (O.°.), hydroxyl radical (OH°.); but also nonradical molecule like hydrogen peroxide (H.O.). ROS play a critical role in several physiological functions like proliferation and signalling pathways. Thanks to cellular (oxidant/antioxidant) systems, ROS level is tightly regulated to avoid exce作者: Hla461 時間: 2025-3-27 20:52 作者: 開玩笑 時間: 2025-3-28 01:04 作者: 制定 時間: 2025-3-28 03:33 作者: jungle 時間: 2025-3-28 09:47
Senescence-Like Phenotypes in Human Nevi,li. Senescence is a critical and potent defense mechanism that mammalian cells use to suppress tumors. While there are many ways to induce a senescence response, oncogene-induced senescence (OIS) remains the key to inhibiting progression of cells that have acquired oncogenic mutations. In primary ce作者: Abrade 時間: 2025-3-28 13:00
Detection of Oncogene-Induced Senescence In Vivo, suggested to function as a cancer cell intrinsic mechanism to restrain tumor growth and has been implicated as a key mechanism preventing the progression of certain premalignant lesions in genetically engineered mouse models of cancer. The senescent phenotype can be defined by two criteria that inc作者: 業(yè)余愛好者 時間: 2025-3-28 15:26
Detection of Senescence Markers During Mammalian Embryonic Development, initially screen and detect senescent cells in heterogeneous cell populations both in vitro and in vivo. However, SAβ-gal staining is not an unequivocal marker of the senescent state, and diagnosis of such usually requires additional markers demonstrating an absence of proliferation and expression 作者: Banquet 時間: 2025-3-28 21:16
Hengrui Zhu,Linh Le,Hsin-Yao Tang,David W. Speicher,Rugang Zhang Ph.D.ees, the main cost driver is network infrastructure (Ellingeret al. , 2002). Radio network planning can cut operational and capital expenditure by up to 30 % (Dehghan, 2005). Good radio network planning is difficult for UMTS, because its radio interface is more complex than anything used at mass-mar作者: Synapse 時間: 2025-3-29 00:16 作者: PRO 時間: 2025-3-29 05:25
Mohammad Althubiti,Salvador MacipT execu tive or experienced consultant not knowing the complete application already. Actually working in an application is the best way to learn it. Therefore, the chapters of this book include exercises that build up on each other in a comprehensive case study. If you need support to solve the exer作者: 隱藏 時間: 2025-3-29 08:29 作者: Aspiration 時間: 2025-3-29 14:42
Andrew Joselow,Darren Lynn,Tamara Terzian,Neil F. Boxomit kann der Leser parallel zu den erl?uterten Funktionen das Erlernte sofort praktisch anwenden und festigen. Der Anspruch des Buches ?kurz & bündig“ kann nur eine Auswahl der grund- genden Elemente eines komplexen CAD/CAM/CAE-Systems wie NX5 abbilden. Daher gilt besonderes Augenmerk auf das Erler作者: 重疊 時間: 2025-3-29 17:55 作者: 不能仁慈 時間: 2025-3-29 19:58 作者: 移植 時間: 2025-3-30 02:44 作者: Mystic 時間: 2025-3-30 07:59
Detecting Markers of Therapy-Induced Senescence in Cancer Cells, collectively impinging on tumor control and clinical outcome. Hence, TIS research is gaining pivotal interest from both a tumor biological and a therapeutic perspective, and the development of non-DNA damaging, senescence-evoking therapeutics is about to become a major research objective. In this c作者: Yag-Capsulotomy 時間: 2025-3-30 08:19 作者: babble 時間: 2025-3-30 16:27 作者: indubitable 時間: 2025-3-30 19:11
Detection of Oncogene-Induced Senescence In Vivo,ave been found to be nonspecific. However, the use of multiple markers is accepted as confirmation of senescence in vivo. Here, we describe protocols for some of the most commonly used indicators of senescence in oncogenic .-induced lung adenomas including the detection of senescence-associated beta作者: 牙齒 時間: 2025-3-31 00:30 作者: 搜集 時間: 2025-3-31 03:32
Mikhail A. Nikiforov,Donna S. Shewachurch eine Richtlinie der Arbeitsbedingungen bei der Bildschirmarbeit anzunehmen. Die EG-Bildschirm-Richtlinie (1990), die in Deuts- land durch die Bildschirmarbeitsverordnung vom 4. Dezember 1996 in nationales Re978-3-8348-9404-5作者: Myosin 時間: 2025-3-31 06:56 作者: Carcinogen 時間: 2025-3-31 09:48
1064-3745 cence: Methods and Protocols.?represents a valuable asset for a wide audience of medical oncologists and researchers in the fields of oncology, molecular and cellular biology, biochemistry, and animal development..978-1-4939-8267-7978-1-4939-6670-7Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 燒烤 時間: 2025-3-31 14:33 作者: 蔑視 時間: 2025-3-31 17:51
Michael Shtutman,Bey-Dih Chang,Gary P. Schools,Eugenia V. Broude Ph.D.作者: vector 時間: 2025-4-1 00:08 作者: 欲望小妹 時間: 2025-4-1 04:31
978-1-4939-8267-7Springer Science+Business Media New York 2017作者: Hemiparesis 時間: 2025-4-1 08:49
Oncogene-Induced Senescence978-1-4939-6670-7Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: Toxoid-Vaccines 時間: 2025-4-1 10:09 作者: 價值在貶值 時間: 2025-4-1 16:34 作者: Negligible 時間: 2025-4-1 21:51
https://doi.org/10.1007/978-1-4939-6670-7Senescent cells; Phenotypes; Cellular processes; Oncology; Oncoproteins作者: refine 時間: 2025-4-2 00:03
Mikhail A. NikiforovIncludes cutting-edge methods and protocols for the study of oncogene-induced senescence.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice fr作者: Adulate 時間: 2025-4-2 04:31 作者: HAVOC 時間: 2025-4-2 07:57 作者: Guaff豪情痛飲 時間: 2025-4-2 11:33
Book 2015n this philosophical analysis of Marx‘s never-before translated German notes on Machiavelli, Montesquieu, Rousseau, and Lewis Henry Morgan, Norman Fischer points to a strain of Marxist ethics that may only be understood in the context of the great works of Western political theory and philosophy par
