標(biāo)題: Titlebook: Oncogene and Transgenics Correlates of Cancer Risk Assessments; Constantine Zervos Book 1992 Springer Science+Business Media New York 1992 [打印本頁] 作者: intensify 時間: 2025-3-21 19:42
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作者: 羅盤 時間: 2025-3-21 23:00 作者: Carcinogenesis 時間: 2025-3-22 03:24
https://doi.org/10.1007/978-1-4615-3056-5Embryo; biochemistry; genes; genetics; molecular biology; physiology; transgenic animals作者: recession 時間: 2025-3-22 07:08
K-, Oncogene Activation in Neoplasias of Patients with Familial Adenomatous Polyposis or Kidney Tration in this complex system resulting from structural modification of a normal gene or of its controlling regions, is called oncogene activation. However, no specific correlation has been demonstrated that was relevant to this process, during the carcinogenesis, until the detection of point mutations in total genomic DNA became feasible (1).作者: compose 時間: 2025-3-22 09:20 作者: conservative 時間: 2025-3-22 15:05 作者: 營養(yǎng) 時間: 2025-3-22 17:37 作者: 松馳 時間: 2025-3-23 00:48
schland erste Ans?tze einer Umweltpolitik zu erkennen sind. So stellte bereits 1952 die aus Bundes- und Landespolitikern zusammengesetzte “Interparlamentarische Arbeitsgemeinschaft für naturgem??e Wirtschaftsweise” ihre “Grunds?tze einer ?kologiegerechten Politik” zur Diskussion (vgl. Malunat (1974)作者: 共同給與 時間: 2025-3-23 04:55
Elizabeth L. Andersonthms. My goal is to contribute a closer look at algorithmic issues that arise from complex forms of the underlying pricing models-issues many practitioners need to solve sooner or later in their careers. This book takes such a close look at uncertain volatility models, an exten- sion of Black-Schole作者: 古文字學(xué) 時間: 2025-3-23 05:40
Suresh H. Moolgavkarthms. My goal is to contribute a closer look at algorithmic issues that arise from complex forms of the underlying pricing models-issues many practitioners need to solve sooner or later in their careers. This book takes such a close look at uncertain volatility models, an exten- sion of Black-Schole作者: GAVEL 時間: 2025-3-23 09:46 作者: 暴發(fā)戶 時間: 2025-3-23 14:26
Kevin R. O’Driscoll,Scott M. Kahn,Christoph M. Borner,Wei Jiang,I. Bernard Weinsteinthms. My goal is to contribute a closer look at algorithmic issues that arise from complex forms of the underlying pricing models-issues many practitioners need to solve sooner or later in their careers. This book takes such a close look at uncertain volatility models, an exten- sion of Black-Schole作者: syring 時間: 2025-3-23 20:51 作者: Induction 時間: 2025-3-23 23:51 作者: Curmudgeon 時間: 2025-3-24 05:41
Monique Castagna,Jacqueline Robert Lezenes,Xupei Huang,Nicole Hananialichkeiten sichern, sich von den Mitbewerbern abheben und—ganz wesentlich — dem Kunden (Anwender) positive Erfahrungen vermitteln. Das bringt neue Herausforderungen, aber auch neue M?glichkeiten für Designer und Entwickler mit sich, Anwender eingehender, auf sinnvollere Art und Weise zu verstehen. D作者: FORGO 時間: 2025-3-24 09:59 作者: 留戀 時間: 2025-3-24 10:56 作者: Gum-Disease 時間: 2025-3-24 18:01 作者: florid 時間: 2025-3-24 21:37 作者: 使高興 時間: 2025-3-25 02:03 作者: Emmenagogue 時間: 2025-3-25 06:39 作者: headlong 時間: 2025-3-25 11:33
Chang-Ho Ahn,Won-Chul Choiu werden. Vor 550 Mio. Jahren brach das Leben in Form von gr??eren und vielgestaltigen Tieren geradezu über die Ozeane herein. Es handelt sich um die so genannte kambrische Explosion des Lebens. Innerhalb einer relativ kurzen Zeitspanne entwickelten sich s?mtliche Tierst?mme (die systematischen Kate作者: 致命 時間: 2025-3-25 13:20
Helga Spieker-Polet,Periannan Sethupathi,Herman Polet,Pi-Chen Yam,Katherine L. Knightgen. Lediglich Planeten und Monde mit festem Oberfl?chenmaterial bieten Oasen für Leben, wie wir es kennen. Darüber hinaus sind unter den Planeten mit fester Oberfl?che die wenigsten einladend. Wie wir in der Einleitung dieses Buches festgestellt haben, ist die Erde unter allen bekannten Himmelsk?rp作者: BROW 時間: 2025-3-25 18:25
Rory B. Conolly,Kannan Krishnan,Melvin E. Andersenps working in this field.Includes supplementary material: This volume is a collection of papers presented at the Twelfth International Conference on Ultrafast Phenomena held at Charleston, SC, from July 9 to 13, 2000. The Ultrafast Phenomena Conferences are held every two years and provide a forum f作者: genesis 時間: 2025-3-25 22:42
Gail Charnley13, 2000. The Ultrafast Phenomena Conferences are held every two years and provide a forum for discussion of the latest results in ultrafast optics and their applications in science and engineering. A total of more than 200 papers was presented, reporting progress in the technology of generating and作者: theta-waves 時間: 2025-3-26 02:31 作者: Incise 時間: 2025-3-26 06:09 作者: 四指套 時間: 2025-3-26 10:57
Cancer Risk Assessments: An Overview,ociated with toxic chemical exposures. This two-step process, first to evaluate risk and then to decide what, if anything, should be done to reduce exposures, was adopted by the U.S. Environmental Protection Agency (EPA) in 1976 its announcement of guidelines for assessing cancer risk (EPA 1976, Alb作者: Orchiectomy 時間: 2025-3-26 14:22 作者: obstinate 時間: 2025-3-26 20:31
Predictive Value for Cancer Risk Assessment of Cell- and Tissue- Specific Formation of Carcinogen-Dogenic events selected on the basis of the advantage they confer to the process of tumor development. For risk assessment of such (groups of) compounds it is important to elucidate the working mechanisms by which they contribute to the generation of the oncogenic events underlying the formation of t作者: Carcinogenesis 時間: 2025-3-26 23:00
Studies on the Role of Protein Kinase C in Multistage Carcinogenesis and Their Relevance to Risk ExA appears to exert its biologic effects through protein kinase C (PKC), a key enzyme in signal transduction, we have studied this enzyme in considerable detail. To explore the role of PKC in carcinogenesis we developed various types of cell lines that overproduce the PKC. isoform. To gain further in作者: machination 時間: 2025-3-27 01:12
Oncogene Activation and Human Cancer, Two main approaches have lead to the identification of oncogenes (reviewed in ref. 1). The first came from the studies of acutely transforming retroviruses. These viruses transform susceptible cells and their transforming genes e.g. ., ., ., etc., have nucleotide sequence homology to cellular seque作者: hemorrhage 時間: 2025-3-27 07:42 作者: engrossed 時間: 2025-3-27 11:54
Protein Kinase C in Carcinogenesis: Comparative Expression of Oncogenes and Protein Kinase C in Rhan, were first described in the model of chemical carcinogenesis developed on mouse skin (1). Initiation resulted from the action of potent mutagens likely responsible for activation of protooncogenes or inactivation of growth suppressor genes, whereas promotion was associated with epigenetic alterat作者: Hyperlipidemia 時間: 2025-3-27 16:55
Oncogenes and Human Cancers,erlie the multi-factorial etiology and multistage progression of the tumors, although in most cases the precise sequence of genetic events remains unclear. The mechanisms of carcinogenesis are probably the most important single question in cancer research, because when we understand the process of m作者: 不利 時間: 2025-3-27 18:58
K-, Oncogene Activation in Neoplasias of Patients with Familial Adenomatous Polyposis or Kidney Tration in this complex system resulting from structural modification of a normal gene or of its controlling regions, is called oncogene activation. However, no specific correlation has been demonstrated that was relevant to this process, during the carcinogenesis, until the detection of point mutation作者: Basilar-Artery 時間: 2025-3-28 00:43
An Overview of Transgenic Mice as Future Models of Human Diseases, in Drug Development, and for Gena discipline drawing upon the strategies and techniques which form the cornerstones of both basic and applied research from animal husbandry to zoology, the knowledge base in organic chemistry and biochemistry, the vast literature on the genetics, molecular, and cell biology of both prokaryotes and 作者: Inculcate 時間: 2025-3-28 04:07 作者: Stress-Fracture 時間: 2025-3-28 07:47
Genes and Oncogenes of the , Superfamily,d to the rediscovery of one of the three closely related genes: H-., K-. (first found as the cellular genomic sequences (oncogenes) transduced in the Harvey and Kirsten sarcoma viruses) and N-.. The three . genes code for 21kD GTP/GDP binding proteins; they are transiently anchored at the inner face作者: GUMP 時間: 2025-3-28 13:44
Oncogenic Transgenic Mice in the Study of Carcinogenesis, the mechanism of oncogenesis, and the other to examine the carcinogenic potential of chemicals. The research on carcinogenic mechanisms explores a multistep series of events of carcinogenesis, environmental and endogenous factors, and various genes and transcriptional elements (1,2). Research on th作者: 卡死偷電 時間: 2025-3-28 16:23 作者: 為現(xiàn)場 時間: 2025-3-28 21:11
An Overview of the Outstanding Issues in the Risk Assessment of Methylene Chloride,mechanistic knowledge of both target tissue dosimetry (pharmacokinetics) and of the tissue responses culminating in tumor development (pharmacodynamics). A major step in this direction was taken by Andersen et al. (Toxicol. Appl. Pharmacol., 87:185, 1987) who used a physiologically based pharmacokin作者: 多余 時間: 2025-3-29 01:10 作者: insomnia 時間: 2025-3-29 03:21 作者: 失敗主義者 時間: 2025-3-29 11:00
An Overview of Transgenic Mice as Future Models of Human Diseases, in Drug Development, and for Geny, the knowledge base in organic chemistry and biochemistry, the vast literature on the genetics, molecular, and cell biology of both prokaryotes and eukaryotes, and the current and rapidly accumulating databases on HIV, oncogenes, and the human genome.作者: EPT 時間: 2025-3-29 13:52 作者: flavonoids 時間: 2025-3-29 16:45 作者: gerrymander 時間: 2025-3-29 20:41
Genes and Oncogenes of the , Superfamily,ne ruffling, cell motility, etc…) and loss of contact inhibition. Ras proteins are highly conserved throughout evolution and are found in all eucaryotic organisms where they must exert essential functions. In spite of intense investigation the precise biochemical role of the ras proteins remains elusive(1).作者: Pantry 時間: 2025-3-29 23:52
Book 1992 for the most part, from the applied biological disciplines, e. g. , toxicology, epidemiology, biostatistics, etc. The more fundamental biological disciplines, e. g. , biochemistry, cell biology, molecular biology, molecular genetics of cancer, etc. , have enormous but unrealized potential to improv作者: Concrete 時間: 2025-3-30 06:28 作者: 先驅(qū) 時間: 2025-3-30 11:26
Studies on the Role of Protein Kinase C in Multistage Carcinogenesis and Their Relevance to Risk Exine. These studies provide genetic evidence that PKC plays a critical role in growth control and the action of certain growth factors, tumor promoters and oncogenes. The findings are discussed within the context of multistage carcinogenesis, risk assessment, and cancer prevention.作者: MELON 時間: 2025-3-30 13:35 作者: Magisterial 時間: 2025-3-30 18:21 作者: 手術(shù)刀 時間: 2025-3-30 23:04
rechtstats?chlichen Hintergrund und die Entwicklung des Umweltrechts in der Bundesrepublik). Ebenfalls 1971 wird in der DDR das Ministerium für Umweltschutz und Wasserwirtschaft gegründet, zu dessen Aufgaben insbesondere die Ausarbeitung der strategischen Linien des Umweltschutzes sowie die Koordin作者: 薄膜 時間: 2025-3-31 01:47
Demetrios A. Spandidos,Margaret L. M. Andersonchen Bildung mit Umweltbildung befassen. Ausgeschlossen waren auch die Angebote der Massenmedien, deren Bedeutung für die Entstehung des Umweltbewusstseins in der Bev?lkerung allerdings zentral ist (vgl. de Haan 1995; de Haan/Kuckartz 1996b). Von unserer Seite wurde zudem der Bereich der Umweltbildu作者: GORGE 時間: 2025-3-31 06:26
Tommaso A. Dragani,Giacomo Manenti,Manuela Gariboldi,F. Stefania Falvella,Marco A. Pierotti,Giuseppechen Bildung mit Umweltbildung befassen. Ausgeschlossen waren auch die Angebote der Massenmedien, deren Bedeutung für die Entstehung des Umweltbewusstseins in der Bev?lkerung allerdings zentral ist (vgl. de Haan 1995; de Haan/Kuckartz 1996b). Von unserer Seite wurde zudem der Bereich der Umweltbildu作者: 擔(dān)憂 時間: 2025-3-31 13:03
Monique Castagna,Jacqueline Robert Lezenes,Xupei Huang,Nicole Hananiaind. Kulturanthropologen bezeichnen diese Methode der kontextuellen Untersuchung als Ethnographie, eine Untersuchungsmethode, um die kulturellen Beziehungen und Interaktionen zwischen Menschen, Gegenst?nden und Umgebungen zu verstehen. Die ethnographische Untersuchung bzw. die User Experience Resear作者: 有雜色 時間: 2025-3-31 16:59 作者: 袖章 時間: 2025-3-31 20:53
Ramon Mangues,Angel Pellicereinem Testorganismus, der einem belasteten Sediment ausgesetzt wurde. Bei der Differenzierung von toxischen Effekten sedimentassoziierter Schadstoffe müssen jedoch sowohl die Sensitivit?ten von Testorganismen als auch die m?glichen Aufnahmewege der Chemikalien berücksichtigt werden. Dieses Kapitel b作者: fiscal 時間: 2025-3-31 23:16 作者: 最高點(diǎn) 時間: 2025-4-1 05:20 作者: indifferent 時間: 2025-4-1 08:36
David M. Ornitz,Radek Skoda,Randall W. Moreadith,Philip Lederscher Prozess, in dem die Abtrennung des sandigen Materials vom schadstoffbeladenen Schlick erfolgt. Korngr?βenverteilungen liefern wichtige Informationen zur Repr?sentanz von Probenahmestellen und erm?glichen unter Einbeziehung weiterer Daten Absch?tzungen über zu verbringende Sedimentmengen bei Un作者: 表被動 時間: 2025-4-1 12:54
Armand Tavitianeinem Testorganismus, der einem belasteten Sediment ausgesetzt wurde. Bei der Differenzierung von toxischen Effekten sedimentassoziierter Schadstoffe müssen jedoch sowohl die Sensitivit?ten von Testorganismen als auch die m?glichen Aufnahmewege der Chemikalien berücksichtigt werden. Dieses Kapitel b作者: 河潭 時間: 2025-4-1 16:10 作者: guardianship 時間: 2025-4-1 21:15
Helga Spieker-Polet,Periannan Sethupathi,Herman Polet,Pi-Chen Yam,Katherine L. Knighte Bildung und die Evolution des Planeten Erde beschreiben. Die Kenntnis dessen, wie die Erde ihre lebensspendenden Eigenschaften erlangte, dient als Grundlage für das Verst?ndnis dafür, was Leben braucht und mit welcher Wahrscheinlichkeit es anderswo existiert.作者: ABHOR 時間: 2025-4-2 00:50 作者: Ophthalmoscope 時間: 2025-4-2 02:49
