標(biāo)題: Titlebook: Nuclear Receptors; Current Concepts and Chris M. Bunce,Moray J. Campbell Book 2010 Springer Science+Business Media B.V. 2010 ATP.Metazoa.Vi [打印本頁(yè)] 作者: 駝峰 時(shí)間: 2025-3-21 19:00
書(shū)目名稱Nuclear Receptors影響因子(影響力)
作者: 有惡臭 時(shí)間: 2025-3-22 00:04 作者: 箴言 時(shí)間: 2025-3-22 03:25
Gabriel Markov,Fran?ois Bonneton,Vincent Laudetay area as a semi-legal market, the authors cover important issues ranging from athletes most at risk to the role of organized crime in sports doping, and whether sports governing bodies are enabling the trade. Challenges for law enforcement and legislation, and efforts to control PED use in the wor作者: Small-Intestine 時(shí)間: 2025-3-22 06:22 作者: 噴出 時(shí)間: 2025-3-22 11:50
Robert H. Oakley,John A. Cidlowskiay area as a semi-legal market, the authors cover important issues ranging from athletes most at risk to the role of organized crime in sports doping, and whether sports governing bodies are enabling the trade. Challenges for law enforcement and legislation, and efforts to control PED use in the wor作者: 舊式步槍 時(shí)間: 2025-3-22 16:39 作者: deactivate 時(shí)間: 2025-3-22 17:55
James T. Dalton,Wenqing Gaons for anti-doping policies and effective criminal justice o.??This book examines sports doping from production and distribution, detection and punishment. Detailing the daily operations of the trade and its gray area as a semi-legal market, the authors cover important issues ranging from athletes m作者: gastritis 時(shí)間: 2025-3-22 23:56 作者: incisive 時(shí)間: 2025-3-23 04:14 作者: maverick 時(shí)間: 2025-3-23 07:55 作者: DOLT 時(shí)間: 2025-3-23 11:43
Linda M. Sanderson,Sander Kerstenilroad, car rental or hotel companies. Its application to the small and medium sized businesses that characterise the tourism industry in many countries, Italy in the first place, has never been totally excluded, but its implementation and subsequent actuation has always been considered too expensiv作者: 配置 時(shí)間: 2025-3-23 16:43 作者: Jacket 時(shí)間: 2025-3-23 18:56
Yandong Wang,Weidong Chen,Xiaosong Chen,Wendong Huangssed margin? And with what organisational form does yield management best develop its potential? Innovations regarding organisational structure and work organisation in hotels have placed in doubt the role and position which yield management currently holds in hotels. This paper analyses, first of a作者: 不易燃 時(shí)間: 2025-3-24 00:43
Su Liu,Shaozhen Xie,Yi-fen Lee,Chawnshang Changilroad, car rental or hotel companies. Its application to the small and medium sized businesses that characterise the tourism industry in many countries, Italy in the first place, has never been totally excluded, but its implementation and subsequent actuation has always been considered too expensiv作者: Hemiparesis 時(shí)間: 2025-3-24 04:53 作者: infantile 時(shí)間: 2025-3-24 06:42 作者: RAFF 時(shí)間: 2025-3-24 11:11 作者: nugatory 時(shí)間: 2025-3-24 18:05 作者: coagulation 時(shí)間: 2025-3-24 19:25
F.J. Bruggeman,A. Kolodkin,K. Rybakova,M. Moné,H.V. Westerhoffation is often dispersed in a variety of books, journals and online resources. This encyclopedia presents the latest facts about all known viruses in a standardized form created by hundreds of the world‘s leading virologists. .Virus taxonomy represents the basic framework that allows an understandin作者: Conclave 時(shí)間: 2025-3-25 01:19 作者: 暴發(fā)戶 時(shí)間: 2025-3-25 04:32
Nuclear Receptors an Introductory Overview,h the novice and experienced nuclear receptor biologist. For the novice it will provide a background scaffold for the forthcoming chapters. For the most experienced it will serve as a timely reminder of what fun we have had and how far this vitally important field has come since the first report of 作者: GLOSS 時(shí)間: 2025-3-25 08:40
What does Evolution Teach us about Nuclear Receptors?,ir diversity can be helpful to make insights about their evolution. Significant attention is paid to the evolution of ligand-binding ability. Recent evolutionary and functional data have challenged the traditional concept of ligand, providing a more complex view of the mechanisms by which the transc作者: Neuralgia 時(shí)間: 2025-3-25 14:12 作者: preservative 時(shí)間: 2025-3-25 16:16
The Glucocorticoid Receptor,ammation, and apoptosis. Drugs that mimic the actions of glucocorticoids are widely used to treat diseases such as cancer, inflammation, and autoimmune disorders. The effects of glucocorticoids and their synthetic derivatives are mediated by the glucocorticoid receptor (GR, NR3C1), a member of the n作者: PAN 時(shí)間: 2025-3-25 21:27 作者: 蠟燭 時(shí)間: 2025-3-26 04:02
Androgen Receptor,ihydrotestosterone (5α-DHT). AR function can be regulated by the binding of its ligands, either agonists or antagonists, which initiate sequential conformational changes of the receptor that will affect receptor function. At the cellular level, AR mainly acts as a transcription factor to regulate do作者: recede 時(shí)間: 2025-3-26 07:25 作者: Junction 時(shí)間: 2025-3-26 10:53
The Vitamin D Receptor (NR1I1),edes the isolation of the receptor by approximately 300 years. The VDR plays a significant role in regulating serum calcium levels through its actions on the cellular machinery to absorb calcium in the gut, to re-absorb it in the kidneys and deposit it in the bones. Consequently, insufficiency of th作者: 流逝 時(shí)間: 2025-3-26 15:40
Retinoic Acid Receptors,s cell growth, differentiation and death. The retinoic acid (RA) signalling pathway involves the precise regulation of retinoid levels and the control of RA-dependent gene expression in target cells. The effects are mainly mediated by two types of nuclear receptors – retinoic acid receptors and reti作者: cardiac-arrest 時(shí)間: 2025-3-26 20:44
PPARs: Important Regulators in Metabolism and Inflammation,ubtype is characterized by a specific tissue expression pattern, partially accounting for distinct biological functions. Analogous to many other nuclear receptors, PPARs form heterodimers with the retinoid X receptor and regulate DNA transcription by binding to specific response elements present in 作者: enormous 時(shí)間: 2025-3-26 21:23 作者: 武器 時(shí)間: 2025-3-27 03:11 作者: 歡樂(lè)中國(guó) 時(shí)間: 2025-3-27 05:21 作者: 賞錢 時(shí)間: 2025-3-27 09:43 作者: Jacket 時(shí)間: 2025-3-27 15:09 作者: laceration 時(shí)間: 2025-3-27 19:05 作者: ACE-inhibitor 時(shí)間: 2025-3-28 01:45
New Insights to Nuclear Receptor Gene Regulation from Analysis of their Response Elements in Target target genes are also involved in dysregulated pathways that can lead to common human diseases, such as type 2 diabetes, atherosclerosis, Alzheimer’s disease and cancer. On the genomic level these pathways converge on regulatory modules, some of which contain co-localizing NR binding sites, so-call作者: Merited 時(shí)間: 2025-3-28 04:59
Systems Biology: Towards Realistic and Useful Models of Molecular Networks,lenging our thinking about cells. Cells turn out be complicated molecular systems displaying multivariate dynamics that can rarely be understood in terms of single molecules. One way to appreciate this complexity is to make mathematical models of signaling, gene, and metabolic network to assess the 作者: AVID 時(shí)間: 2025-3-28 07:18
Proteins and Cell Regulationhttp://image.papertrans.cn/n/image/668677.jpg作者: mucous-membrane 時(shí)間: 2025-3-28 10:40
https://doi.org/10.1007/978-90-481-3303-1ATP; Metazoa; Vitamin D; development; estrogen receptor; glucocorticoid; hormone receptors; metabolism; nucl作者: 腫塊 時(shí)間: 2025-3-28 16:06
Chris M. Bunce,Moray J. CampbellFocuses on biology of nuclear receptors.Up to date reviews of diverse aspects of Nuclear Receptor biology.Contributions from authors of major standing in the Nuclear Receptor Field.Provides an outstan作者: cringe 時(shí)間: 2025-3-28 20:20 作者: 倔強(qiáng)一點(diǎn) 時(shí)間: 2025-3-29 02:00 作者: Abnormal 時(shí)間: 2025-3-29 03:59 作者: 墻壁 時(shí)間: 2025-3-29 08:44
What does Evolution Teach us about Nuclear Receptors?,riptional activity of NRs can be modulated. Finally, we argue that the evolutionary analysis of NRs has contributed to a conceptual shift of our understanding of nuclear receptors, from highly specific endocrine regulators to a promiscuous metabolic rheostat.作者: 名字 時(shí)間: 2025-3-29 14:21
Functions of Nuclear Receptors in Insect Development,fined critical roles for nuclear hormone receptors in controlling embryonic development, molting, metamorphosis, reproduction and metabolism. In this chapter, I review our understanding of the biological functions of all insect nuclear hormone receptors.作者: Emmenagogue 時(shí)間: 2025-3-29 19:23
Thyroid Hormone Receptors, factors. These receptors are particularly versatile since they also have the potential to mediate ligand-independent transcriptional control. Genetic analyses have revealed both specific and overlapping roles for each receptor, revealing how a small receptor family can mediate an extended range of biological functions.作者: white-matter 時(shí)間: 2025-3-29 21:27 作者: 史前 時(shí)間: 2025-3-30 02:08
Systems Biology: Towards Realistic and Useful Models of Molecular Networks,systemic consequences of specific molecular perturbations. This chapter gives a brief overview of some of the approach in mathematical modeling of molecular networks. We choose to keep the mathematical detail minimal and highlight a number of concepts and approaches that are emerging in the analysis of molecular networks.作者: 道學(xué)氣 時(shí)間: 2025-3-30 06:45 作者: municipality 時(shí)間: 2025-3-30 12:10
The Vitamin D Receptor (NR1I1), on the cellular machinery to absorb calcium in the gut, to re-absorb it in the kidneys and deposit it in the bones. Consequently, insufficiency of the VDR ligand 1α,25dihydroxyvitaminD. (1α25(OH).D.) in a child leads to the classic symptoms of rickets.作者: 啞巴 時(shí)間: 2025-3-30 16:19
Fxr,itional functions of FXR are identified in enteroprotection, liver regeneration, cancer and aging. These exciting findings suggest that FXR has a broader role than previously thought, and also highlight potential opportunities for using FXR as a drug target for different diseases.作者: insipid 時(shí)間: 2025-3-30 18:14 作者: 啜泣 時(shí)間: 2025-3-30 22:18 作者: Outspoken 時(shí)間: 2025-3-31 02:34 作者: 漸強(qiáng) 時(shí)間: 2025-3-31 06:14
Ligand Regulation and Nuclear Receptor Action,se or decrease the local concentration of nuclear receptor ligands. The following chapter describes examples of these pathways for regulation of nuclear receptor ligands and their developing importance as therapeutic targets for human disease.作者: NUDGE 時(shí)間: 2025-3-31 11:18
The Glucocorticoid Receptor,gene regulatory profiles. Here, we discuss the molecular and cellular mechanisms of GR signaling, and the potential role for GR isoforms in regulating the specificity and sensitivity of glucocorticoid responsiveness in healthy and diseased tissues.作者: Introvert 時(shí)間: 2025-3-31 14:58 作者: 刪減 時(shí)間: 2025-3-31 18:59
Androgen Receptor,of androgens in many of these conditions. With the rapidly increasing knowledge of AR protein structure and molecular mechanism of action in the last few decades, a large variety of nonsteroidal ligands, have been developed to selectively modulate AR action with much improved tissue and/or function 作者: 強(qiáng)有力 時(shí)間: 2025-3-31 22:58 作者: 值得贊賞 時(shí)間: 2025-4-1 05:17
Xenobiotic Receptors CAR and PXR,s of CAR are modulated by phosphorylation as well as various coactivators and corepressors. By binding to multiple DNA response elements that CAR and PXR share with other nuclear receptors, physically interacting with other nuclear receptors, and/or competing with other nuclear receptors for the lim作者: 裹住 時(shí)間: 2025-4-1 07:59
Physiological Functions of TR2 and TR4 Orphan Nuclear Receptor, al. 2005, . 25(7), 2722–2732; Mu et al. 2004, . 24(13), 5887–5899; Collins et al. 2004, . 101(42), 15058–15063). Mice with a germline deletion of TR4 are viable but have high early postnatal mortality, growth retardation, and profound reduction in body weight. Further studies showed that TR4 plays 作者: Heretical 時(shí)間: 2025-4-1 12:01 作者: Amplify 時(shí)間: 2025-4-1 16:13
Book 2010n of the capacity, productivity and value of international human scientific endeavour. Based on intrigue, lively competition and cooperation a global effort has rapidly fostered a school of biology with widespread ramifications for the understanding of metazoan animals, the human condition and the s
