標(biāo)題: Titlebook: Novel Chemical Tools to Study Ion Channel Biology; Christopher Ahern,Stephan Pless Book 2015 The Editor(s) (if applicable) and The Author( [打印本頁] 作者: 壓縮 時間: 2025-3-21 17:24
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作者: DOSE 時間: 2025-3-21 22:19 作者: 教義 時間: 2025-3-22 01:41
0065-2598 spectroscopy, all combined with traditional techniques of electrophysiology and molecular biology. .Novel Chemical Tools to Study Ion Channel Biology., part of the bestselling .Advances in Experimental Medicine978-1-4939-4762-1978-1-4939-2845-3Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: 冥界三河 時間: 2025-3-22 04:52 作者: epinephrine 時間: 2025-3-22 12:25
Introduction,ver 500 channel-forming subunits known today in humans, this large class of proteins is also increasingly recognised as important drug targets, as inherited or acquired ion channel dysfunction are known causes of disease.作者: Incumbent 時間: 2025-3-22 13:27
Engineered Ionizable Side Chains,e rate of ion conduction in such a way that individual proton-transfer events can be identified in a most straightforward manner. From the extent to which the single-channel current amplitude is reduced every time a proton binds, we can learn about the proximity of the engineered side chain to the l作者: 恃強(qiáng)凌弱 時間: 2025-3-22 17:36 作者: osteoclasts 時間: 2025-3-23 01:01
Functional Site-Directed Fluorometry,functional site-directed fluorometry and its interpretive power should continue to improve, making it an even more powerful technique for dissecting the conformational dynamics of ion channels and other membrane proteins.作者: 驕傲 時間: 2025-3-23 04:17
Flipping the Photoswitch: Ion Channels Under Light Control,e changes in photochrome structure. By acting as light-dependent ion channel agonists, antagonist or modulators, photochromic controllers effectively converted a wide range of ion channels, including voltage-gated ion channels, ‘leak channels’, tri-, tetra- and pentameric ligand-gated ion channels, 作者: Cytology 時間: 2025-3-23 08:11
Book 2015 array of experimental approaches: photochemistry, novel biological tools, and innovative spectroscopy, all combined with traditional techniques of electrophysiology and molecular biology. .Novel Chemical Tools to Study Ion Channel Biology., part of the bestselling .Advances in Experimental Medicine作者: 用手捏 時間: 2025-3-23 09:42 作者: Obvious 時間: 2025-3-23 13:55 作者: 租約 時間: 2025-3-23 19:59 作者: indignant 時間: 2025-3-24 00:35 作者: 有惡臭 時間: 2025-3-24 03:22
https://doi.org/10.1007/978-1-4939-2845-3Biophysics; Bioreactivity; Fluorometry; Ion Channels; Modifications; Proteins作者: 為敵 時間: 2025-3-24 08:57 作者: Excitotoxin 時間: 2025-3-24 14:10
Introduction,ng of this pore can be controlled by a myriad of physiological inputs (voltage, ligands, temperature, metabolites, pH), which in turn allow for the controlled flux of ions across membranes, resulting in the generation of minute electrical signals. The functional implications of ion channel function 作者: 瘙癢 時間: 2025-3-24 17:41 作者: Abutment 時間: 2025-3-24 19:45
Cysteine Modification: Probing Channel Structure, Function and Conformational Change,embrane proteins in their native environment, embedded in phospholipid membranes. Among the 20 amino acids, cysteine is uniquely reactive. This reactivity has motivated the synthesis of a wide array of sulfhydryl reactive chemicals. The commercially available array of sulfhydryl reactive reagents ha作者: Granular 時間: 2025-3-25 02:55
Functional Site-Directed Fluorometry,rected fluorometry has since been expanded to numerous other voltage-gated and ligand-gated ion channels as well as transporters, pumps, and other integral membrane proteins. The power of functional site-directed fluorometry, also known as voltage-clamp fluorometry, lies in its ability to provide in作者: 謙虛的人 時間: 2025-3-25 07:20
Bioreactive Tethers,e tethers are specialized chemical probes that have been used in electrophysiological experiments to provide unique insight into ion channel structure and function. Because bioreactive tethers are small molecular probes, they can be used to manipulate ion channel function in heterologous expression 作者: aesthetic 時間: 2025-3-25 08:53 作者: ATRIA 時間: 2025-3-25 13:43 作者: 最小 時間: 2025-3-25 17:43 作者: Alveoli 時間: 2025-3-25 20:03 作者: UNT 時間: 2025-3-26 02:15
Lilia Leisle,Francis Valiyaveetil,Ryan A. Mehl,Christopher A. Ahernlementary material: The Encyclopedia provides a detailed and comprehensive account of the subject known as public choice. However, the title would not convey suf- ciently the breadth of the Encyclopedia’s contents which can be summarized better as the fruitful interchange of economics, political sci作者: 工作 時間: 2025-3-26 07:39 作者: 尾巴 時間: 2025-3-26 09:27 作者: 按時間順序 時間: 2025-3-26 12:40 作者: Accord 時間: 2025-3-26 20:00 作者: 樂意 時間: 2025-3-26 22:09
0065-2598 rane receptor systems.Covers a wide array of experimental ap.This volume describes chemical approaches to assess ion channel structure, function and pharmacology. Topics discussed include the use of engineered ionizable side chains to obtain information on permeation pathways and the local environme作者: unstable-angina 時間: 2025-3-27 02:26
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