作者: Deceit 時(shí)間: 2025-3-21 23:13 作者: BLANK 時(shí)間: 2025-3-22 00:34
An Oligonucleotide Carrier Based on β-1,3-Glucanse, the total charge of the SPG/nucleotide complex is negative and there is no DNA-compaction problem in this system. Using chemically modified SPG, the antisense effect and CpG immunostimulatory response can be enhanced.作者: 包庇 時(shí)間: 2025-3-22 08:06
Kazunari Taira,Kazunori Kataoka,Takuro NiidomeCovers chemical aspects such as design and synthesis of gene carriers, as well as knowledge from in vivo experiments and clinical aspects of non-viral gene therapy.Complementary information of this bo作者: 有助于 時(shí)間: 2025-3-22 10:16
978-4-431-54738-9Springer-Verlag Tokyo 2005作者: blight 時(shí)間: 2025-3-22 14:22
Overview: Covers chemical aspects such as design and synthesis of gene carriers, as well as knowledge from in vivo experiments and clinical aspects of non-viral gene therapy.Complementary information of this bo978-4-431-54738-9978-4-431-27879-5作者: Obliterate 時(shí)間: 2025-3-22 18:36 作者: maroon 時(shí)間: 2025-3-23 00:05
https://doi.org/10.1007/4-431-27879-6DNA; Nucleotide; RNA; biology; cell biology; chemistry; development; gene; gene expression; gene therapy; gene作者: 埋葬 時(shí)間: 2025-3-23 04:58 作者: mastoid-bone 時(shí)間: 2025-3-23 09:21
Dendrimers as DNA Carriersendrimers and their conjugates is needed in order to improve transfection efficiency and to minimize cytotoxicity and side effects. In addition, the pharmaceutical technological aspects should be emphasized so that the carriers are safe for clinical use.作者: 泰然自若 時(shí)間: 2025-3-23 10:48
Active DNA Release from Complexesds or polymer. Recently, an intracellular signal-responsive artificial gene-regulation system was developed (Katayama et al 2002). This type of system, which responds to endogenous enzymes and hormones, can be an important step in the development of non-viral gene delivery systems capable of active 作者: LEVER 時(shí)間: 2025-3-23 15:03 作者: 細(xì)胞膜 時(shí)間: 2025-3-23 18:09 作者: 愛花花兒憤怒 時(shí)間: 2025-3-23 22:40 作者: Rankle 時(shí)間: 2025-3-24 03:43 作者: 擦掉 時(shí)間: 2025-3-24 09:01
Osam Mazda,Tsunao Kishiday, it is extremely important to delineate OARs according to well-defined uniform guidelines. Uncertainties associated with target volumes and organs-at-risk (OAR) definitions, organ motion, and patient set-up errors stand as obstacles to achieving better outcomes in radiotherapy planning and treatment delivery.作者: Melodrama 時(shí)間: 2025-3-24 14:27
Yoshiyuki Koyamay, it is extremely important to delineate OARs according to well-defined uniform guidelines. Uncertainties associated with target volumes and organs-at-risk (OAR) definitions, organ motion, and patient set-up errors stand as obstacles to achieving better outcomes in radiotherapy planning and treatment delivery.作者: exercise 時(shí)間: 2025-3-24 16:05
Yuichi Yamasaki,Woo-Dong Jang,Nobuhiro Nishiyama,Naoki Kanayama,Kazunori Kataoka作者: integral 時(shí)間: 2025-3-24 19:40 作者: browbeat 時(shí)間: 2025-3-25 02:41 作者: 注意到 時(shí)間: 2025-3-25 03:54 作者: pantomime 時(shí)間: 2025-3-25 07:56 作者: 蹣跚 時(shí)間: 2025-3-25 15:13 作者: 亞當(dāng)心理陰影 時(shí)間: 2025-3-25 16:54
r a given disease site are also concisely reported. In addition to fully meeting the needs ofradiation oncologists, this "know why" and “know how” guide to particle therapy will be valuable for medical physicists, dosimetrists, ?and radiation therapists..作者: 藕床生厭倦 時(shí)間: 2025-3-25 21:44 作者: 苦惱 時(shí)間: 2025-3-26 00:22
Masayuki Yokoyamar a given disease site are also concisely reported. In addition to fully meeting the needs ofradiation oncologists, this "know why" and “know how” guide to particle therapy will be valuable for medical physicists, dosimetrists, ?and radiation therapists..作者: Vsd168 時(shí)間: 2025-3-26 08:14 作者: 傲慢人 時(shí)間: 2025-3-26 10:05
Takanori Kubo,Rumiana Bakalova,Zhivko Zhelev,Hideki Ohba,Masayuki Fujiir a given disease site are also concisely reported. In addition to fully meeting the needs ofradiation oncologists, this "know why" and “know how” guide to particle therapy will be valuable for medical physicists, dosimetrists, ?and radiation therapists..作者: Restenosis 時(shí)間: 2025-3-26 15:04 作者: 殺子女者 時(shí)間: 2025-3-26 20:33 作者: 暗指 時(shí)間: 2025-3-27 00:43 作者: Wallow 時(shí)間: 2025-3-27 01:55
Dendrimers as DNA Carriers conjugates for DNA and ODN delivery in vitro and in vivo..Recently, other biologically functional small nucleic acids, such as small interfering RNA and micro RNA, have been developed for clinical applications. Dendrimers may be useful as carriers for these small RNAs. In fact, we have shown the us作者: 曲解 時(shí)間: 2025-3-27 08:37
An Oligonucleotide Carrier Based on β-1,3-Glucans this carrier compared to other cation types is that the driving force of the complexation is hydrogen bonds instead of electrostatic forces. Therefore, the total charge of the SPG/nucleotide complex is negative and there is no DNA-compaction problem in this system. Using chemically modified SPG, th作者: 縫紉 時(shí)間: 2025-3-27 12:20 作者: 多余 時(shí)間: 2025-3-27 17:06
Active Transport of Exogenous Genes into the Nucleusmmalian cells, factors concerning nucleocytoplasmic transport have steadily been identified. As a result, significant progress has been made in the development of non-viral gene delivery systems capable of nuclear import. Currently, two approaches to active nuclear import of DNA are available. One i作者: 玉米 時(shí)間: 2025-3-27 18:10
Functional Nucleotide Sequences Capable of Promoting Non-viral Genetic Transferhnology (Vijayanathan et al. 2002). Employment of functional genetic elements, such as EBNA1/oriP and the . transposon, may further improve their efficacy, compensating for the shortcomings of non-viral systems. EBV-based plasmid vectors are transported into and maintained in the nucleus as well as 作者: CLASH 時(shí)間: 2025-3-27 22:57
Mahito Nakanishi IMRT, IGRT, motion management, SBRT), (2) a shift away from elective nodal irradiation towards restriction to the primary tumour only. All of the above described changes have been introduced over time and they have not formally been tested as primary endpoints in dedicated trials. This leaves room 作者: 憤怒事實(shí) 時(shí)間: 2025-3-28 03:00 作者: 可觸知 時(shí)間: 2025-3-28 06:48
Hidetaka Akita,Ikramy A. Khalil,Kentaro Kogure,Hideyoshi Harashimaon and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular.? Disease-作者: nonplus 時(shí)間: 2025-3-28 12:58
Takeshi Nagasaki which clinicians and the treatment planning team should pay.This handbook is designed to enable radiation oncologists to treat patients appropriately and confidently by means of particle therapy. The orientation and purpose are entirely practical, in that the focus is on the physics essentials of d作者: 混合 時(shí)間: 2025-3-28 16:05
Masayuki Yokoyamaon and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular.? Disease-作者: 笨拙處理 時(shí)間: 2025-3-28 22:03
Takeshi Kawazu,Takeshi Nagasakion and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular.? Disease-作者: Hdl348 時(shí)間: 2025-3-29 02:40
Takanori Kubo,Rumiana Bakalova,Zhivko Zhelev,Hideki Ohba,Masayuki Fujiion and purpose are entirely practical, in that the focus is on the physics essentials of delivery and treatment planning , illustration of the clinical target volume (CTV) and associated treatment planning for each major malignancy when using particle therapy, proton therapy in particular.? Disease-作者: 使困惑 時(shí)間: 2025-3-29 04:56 作者: ALERT 時(shí)間: 2025-3-29 10:25 作者: 清楚說話 時(shí)間: 2025-3-29 13:18 作者: Glucose 時(shí)間: 2025-3-29 19:23
Karen B. Ghazaryan,Davit G. Piliposyan,Gayane T. Piliposiann Boosting, Bagging, and .. It is more stable than Boosting. In addition, like Bagging and . is amenable to parallel and distributed processing while Boosting is not. This gives . another advantage over Boosting for parallel machine learning and datamining.作者: 全國(guó)性 時(shí)間: 2025-3-29 22:21 作者: 解開 時(shí)間: 2025-3-30 02:04 作者: 看法等 時(shí)間: 2025-3-30 07:11
ional trade, with the ability to gather and administrate the information needed to decide on and manage complex international business transactions, including in- and outsourcing problems, exports and imports..978-3-642-44838-6978-3-642-30403-3
