標(biāo)題: Titlebook: Nitric Oxide and Cancer: Pathogenesis and Therapy; Benjamin Bonavida Book 2015 Springer International Publishing Switzerland 2015 Nitric o [打印本頁] 作者: ARRAY 時(shí)間: 2025-3-21 19:20
書目名稱Nitric Oxide and Cancer: Pathogenesis and Therapy影響因子(影響力)
書目名稱Nitric Oxide and Cancer: Pathogenesis and Therapy影響因子(影響力)學(xué)科排名
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書目名稱Nitric Oxide and Cancer: Pathogenesis and Therapy網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Nitric Oxide and Cancer: Pathogenesis and Therapy被引頻次
書目名稱Nitric Oxide and Cancer: Pathogenesis and Therapy被引頻次學(xué)科排名
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書目名稱Nitric Oxide and Cancer: Pathogenesis and Therapy讀者反饋
書目名稱Nitric Oxide and Cancer: Pathogenesis and Therapy讀者反饋學(xué)科排名
作者: 粗糙濫制 時(shí)間: 2025-3-21 21:49
Benjamin BonavidaExplores the most recent advances in the field of Nitric Oxide (NO) and its relationship to cancer.Includes latest information on NO role in pathogenesis, gene and protein modifications, and therapeut作者: Myosin 時(shí)間: 2025-3-22 02:07
S-Nitrosylation in Cancer Cells: To Prevent or to Cause?umor cells. We, therefore, confronted data from clinical and preclinical studies and discussed their respective anti-tumor effects to determine whether the associations of chemotherapy with NO donor therapy may be considered as novel therapeutic approaches (considered as rational therapeutic interventions).作者: 發(fā)酵劑 時(shí)間: 2025-3-22 08:21 作者: 審問,審訊 時(shí)間: 2025-3-22 09:38 作者: 刪除 時(shí)間: 2025-3-22 14:44 作者: Rinne-Test 時(shí)間: 2025-3-22 18:58
Mechanisms of Nitric Oxide-Dependent Regulation of Tumor Invasion and Metastasis short-lived, pleiotropic molecule that is a key physiological signaling molecule. Emerging evidence suggests that the NOS may be key regulators of tumor invasion and metastasis. However, there are markedly conflicting findings in the literature regarding NO and its role in carcinogenesis and tumor 作者: Anecdote 時(shí)間: 2025-3-22 21:43
Impacts of S-Nitrosylation in Cancer effective signal molecule. In this capacity, NO regulates the activity of a wide range of target proteins through its central function in S-nitrosylation. In the past decade, S-nitrosylation signaling events have garnered an increasing amount of interest with regard to their impacts on malignant ne作者: 積習(xí)難改 時(shí)間: 2025-3-23 03:01
S-Nitrosylation in Cancer Cells: To Prevent or to Cause?umor cells. We, therefore, confronted data from clinical and preclinical studies and discussed their respective anti-tumor effects to determine whether the associations of chemotherapy with NO donor therapy may be considered as novel therapeutic approaches (considered as rational therapeutic interve作者: 難解 時(shí)間: 2025-3-23 08:31
The Emerging Role of Protein ,-Nitrosylation in Cancer Metastasistasis. NO regulates a wide range of tumor-associated proteins through .-nitrosylation, a reversible coupling of a nitroso moiety to a reactive cysteine thiol (SH) group to form an .-nitrosothiol (SNO). In this article, we discuss the various roles of protein .-nitrosylation in cancer development wit作者: Infraction 時(shí)間: 2025-3-23 12:35
Nitric Oxide, Immunity and Cancer: From Pathogenesis to Therapyvely studied, NO, reactive nitrogen species (RNS) and reactive oxygen species (ROS) still maintain their reputation of “double-edge-swords”. However, by examining key issues related to their sources, concentrations and chemical nature and, their locations and neighboring molecules that potentially w作者: STIT 時(shí)間: 2025-3-23 16:39
Regulation of Anti-Tumor Immune Responsesality exists in the response against neoplastic cells. At the same time as NO can exert cytotoxicity against tumor cells it can also inhibit immune reactivity against these cells. The following chapter will recapitulate the basal roles of NO in immune homestasis and immune reactivity against pathoge作者: 漸強(qiáng) 時(shí)間: 2025-3-23 19:24
Nitric Oxide: Immune Modulation of Tumor Growthls of nitric oxide must be regulated carefully to maintain homeostasis. Dysregulation or overproduction of nitric oxide has been implicated in the pathogenesis of many disorders including atherosclerosis, neurodegenerative diseases, autoimmune diseases, and cancer. Tumor-associated generation of NO,作者: 解凍 時(shí)間: 2025-3-24 00:05 作者: Canopy 時(shí)間: 2025-3-24 03:22
Emerging Role of NO-Mediated Therapeuticshenotype characterized by uncontrolled proliferation, increased invasion and metastasis, stimulation of angiogenesis and inhibited apoptosis. Paradoxically, at superphysiological concentrations, a less aggressive phenotype exists, where tumor cells are less likely to metastasize, angiogenesis is inh作者: 變化 時(shí)間: 2025-3-24 09:46 作者: inchoate 時(shí)間: 2025-3-24 13:03
Regulation of Cell Death Signaling by Nitric Oxide in Cancer Cellssponses, including vasodilation, respiration, cell migration, immune response and apoptosis. NO is synthesized by three differentially gene-encoded NOS in mammals: neuronal NOS (nNOS or NOS-1), inducible NOS (iNOS or NOS-2) and endothelial NOS (eNOS or NOS-3). NO may exert its cellular action by cGM作者: Migratory 時(shí)間: 2025-3-24 14:55
he poems she began writing, and continued to write, starting in 1959 is noticeable. Whereas most of Hughes’s ideas for subject matter were historically or geographically based, with a strong component of trees, animals, and natural scenes, many of the poems Plath wrote during these years were about 作者: 纖細(xì) 時(shí)間: 2025-3-24 23:00 作者: BOOR 時(shí)間: 2025-3-25 01:26 作者: Defraud 時(shí)間: 2025-3-25 04:49 作者: 小卷發(fā) 時(shí)間: 2025-3-25 10:22 作者: 出生 時(shí)間: 2025-3-25 14:14 作者: abstemious 時(shí)間: 2025-3-25 15:54
rsona of the father who exists more tangibly in her writing. Otto Plath as readers know him from her fiction and poetry was from the start a highly fictionalized character. According to Plath’s mother, the warm and loving father figure created in her early fiction was “90% her adoring grandfather,” 作者: Opponent 時(shí)間: 2025-3-25 21:21 作者: Gene408 時(shí)間: 2025-3-26 04:11 作者: BYRE 時(shí)間: 2025-3-26 08:07 作者: oracle 時(shí)間: 2025-3-26 11:05 作者: Cosmopolitan 時(shí)間: 2025-3-26 16:15
nifers develop. Tests may be coiled and substructured in diverse complexity. Test walls are secreted and crystallized in meticulous arrangements, composed of organic matter, agglutinated with foreign matter, mineralized with calcite, aragonite, high-magnesium calcite, or silica. There are several th作者: Sinus-Rhythm 時(shí)間: 2025-3-26 18:54
Hermes J. Garbán M.D., Ph.D.have on individual hosts and on host populations, yet there has been little work done to review the importance or frequency of how a parasite influences the organisms it’s host interacts with – it’s host’s immediate community. There is, however, a shift occurring in the way scientists think about mu作者: artless 時(shí)間: 2025-3-27 00:04
Peter Siesj?nifers develop. Tests may be coiled and substructured in diverse complexity. Test walls are secreted and crystallized in meticulous arrangements, composed of organic matter, agglutinated with foreign matter, mineralized with calcite, aragonite, high-magnesium calcite, or silica. There are several th作者: INERT 時(shí)間: 2025-3-27 02:01
Naveena B. Janakiram Ph.D.,Chinthalapally V. Rao Ph.D.bacteria. The endosymbionts include thiotrophs that oxidize sulfur for autotrophic production and methanotrophs that oxidize and assimilate methane. Although most of the pogonophoran and vestimentiferan tubeworms possess single thiotrophic 16S rRNA genes (16S rDNA) related to Gammaproteobacteria, so作者: 內(nèi)閣 時(shí)間: 2025-3-27 09:16
enetically almost identical to . species. . serves as an excellent experimental model for studying the nature of endosymbiosis in which one species propagates inside the cells of other species under precise control through chemical communication between the symbiotic partners. This chapter focuses o作者: 音樂學(xué)者 時(shí)間: 2025-3-27 10:46 作者: Leaven 時(shí)間: 2025-3-27 14:27
Cian M. McCrudden,Helen O. McCarthyn is supported at present (in particular by Margulis in Chapman et al., 2000, and Margulis et al., 2000). In this view, the cilium is regarded as originated from the slender cell of a spirochete that established an external symbiosis with an eukaryotic ancestor; the symbiosis was followed by the fus作者: Asseverate 時(shí)間: 2025-3-27 20:06
Emilia Della Pietra,Valentina Rapozziost to plants of acquiring fixed nitrogen. Nitrogen fixation has been incorporated into eukaryotes via symbiotic, endosymbiotic, and endophytic bacteria but not as true organelles like mitochondria and chloroplasts. We have considered possible explanations for the absence of nitrogen-fixing organell作者: 有危險(xiǎn) 時(shí)間: 2025-3-28 00:39 作者: ARM 時(shí)間: 2025-3-28 03:42 作者: PIZZA 時(shí)間: 2025-3-28 06:33
Book 2015 reviews?significant?advances in the application of NO-mediated drugs. The volume explores nitric oxide?and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With ch作者: radiograph 時(shí)間: 2025-3-28 12:37
pathogenesis, gene and protein modifications, and therapeutAdvances in Nitric Oxide and Cancer is a volume that?serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews?significant?advances in the application of NO-mediated drugs. The volume explores作者: DAFT 時(shí)間: 2025-3-28 17:50
Regulation of Anti-Tumor Immune Responsescts of NO can thus be manipulated by administration of NO donors or by inducing NO secretion from innate immune cells. On the other hand, inhibition of NO release by NOS inhibitors or by inhibition of molecules upstream of NOS induction can boost adaptive immune responses mainly by T cells.作者: 咽下 時(shí)間: 2025-3-28 20:44 作者: 侵蝕 時(shí)間: 2025-3-29 02:44 作者: Loathe 時(shí)間: 2025-3-29 03:28 作者: Malfunction 時(shí)間: 2025-3-29 07:37
Role of Nitric Oxide in the Regulation of the Pro-tumourigenic Hypoxic Phenotype: From Instigation t作者: 枯萎將要 時(shí)間: 2025-3-29 13:14
Inflammation-Associated Carcinogenesis Involves Interaction Between the iNOS/NO and Wnt/β-catenin Siic inhibition of iNOS can decrease Wnt/β-catenin signaling and carcinogenesis. At least three pathways are established for the interaction between iNOS and Wnt signaling: (1) a positive feedback loop established by iNOS causing APC or β-catenin mutation via reactive species, and by Wnt targeting iNO作者: preservative 時(shí)間: 2025-3-29 19:24
Mechanisms of Nitric Oxide-Dependent Regulation of Tumor Invasion and Metastasisges has a tumor-inhibitory effect. The balance between the two as such determines whether a tumor progresses or regresses. This presents a therapeutic opportunity to target tumor invasion and metastasis by either disrupting tumor epithelial NOS expression by NOS inhibition, or by introducing NOS vec