標(biāo)題: Titlebook: Nicotine and Related Alkaloids; Absorption, distribu J. W. Gorrod,J. Wahren Book 1993 Springer Science+Business Media Dordrecht 1993 Oxidat [打印本頁(yè)] 作者: 瘦削 時(shí)間: 2025-3-21 19:43
書目名稱Nicotine and Related Alkaloids影響因子(影響力)
書目名稱Nicotine and Related Alkaloids影響因子(影響力)學(xué)科排名
書目名稱Nicotine and Related Alkaloids網(wǎng)絡(luò)公開度
書目名稱Nicotine and Related Alkaloids網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Nicotine and Related Alkaloids被引頻次
書目名稱Nicotine and Related Alkaloids被引頻次學(xué)科排名
書目名稱Nicotine and Related Alkaloids年度引用
書目名稱Nicotine and Related Alkaloids年度引用學(xué)科排名
書目名稱Nicotine and Related Alkaloids讀者反饋
書目名稱Nicotine and Related Alkaloids讀者反饋學(xué)科排名
作者: Individual 時(shí)間: 2025-3-21 21:59 作者: Binge-Drinking 時(shí)間: 2025-3-22 03:02 作者: nauseate 時(shí)間: 2025-3-22 06:25
Pharmacokinetics of (,)-nicotine and metabolites in humans,owitz .., 1990). Metabolites of nicotine may be pharmacologically active (Clark .., 1965) or may be toxic (Shigenaga ..,1988) and, therefore, it is important to know levels of human exposure. Metabolic data can be used to estimate nicotine intake and exposure to tobacco smoke (Benowitz, 1984; Benowitz and Jacob, 1984a).作者: 值得尊敬 時(shí)間: 2025-3-22 10:22
The metabolic fate of the minor tobacco alkaloids,t 2200 components have been separated from tobacco plant extracts (Schmeltz and Hoffman, 1977) and almost 500 compounds in tobacco smoke have been characterized by gas chromatographic techniques (Schumacher .., 1977).作者: Maximizer 時(shí)間: 2025-3-22 15:09 作者: FEMUR 時(shí)間: 2025-3-22 18:59 作者: 前面 時(shí)間: 2025-3-23 00:56 作者: 易發(fā)怒 時(shí)間: 2025-3-23 03:59
oduction of tobacco as a therapeutic agent against diverse pathologi- cal and physiological conditions resulted in the widespread exposure of people to nicotine, and the subsequent recognition of the pleasurable effects of tobacco consumption. Tobacco may be used for pleasure by smoking it in pipes,作者: 同來(lái)核對(duì) 時(shí)間: 2025-3-23 08:27
policy perspective to discuss sustainable agricultural develThis book provides a non-technical, accessible primer onsustainable agricultural development and its relationship to sustainabledevelopment based on three analytical pillars. The first is to understandagriculture as complex physical-biologi作者: 驚奇 時(shí)間: 2025-3-23 10:37
L. P. Bush,F. F. Fannin,R. L. Chelvarajan,H. R. Burtonpolicy perspective to discuss sustainable agricultural develThis book provides a non-technical, accessible primer onsustainable agricultural development and its relationship to sustainabledevelopment based on three analytical pillars. The first is to understandagriculture as complex physical-biologi作者: prostatitis 時(shí)間: 2025-3-23 16:09
J. W. Gorrod own needs. Starving people in poor nations, obesity in rich nations, increasing food prices, on-going climate changes, increasing fuel and transportation costs, flaws of the global market, worldwide pesticide pollution, pest adaptation and resistance, loss of soil fertility and organic carbon, soil作者: 土坯 時(shí)間: 2025-3-23 21:37 作者: pineal-gland 時(shí)間: 2025-3-23 22:47
G. B. Neurathes, e.g. climate change, energy crisis, economy crisis, dise.Sustainability rests on the principle that we must meet the needs of the present without compromising the ability of future generations to meet their own needs. Starving people in poor nations, obesity in rich nations, increasing food pric作者: fluoroscopy 時(shí)間: 2025-3-24 02:21
P. A. Crookses, e.g. climate change, energy crisis, economy crisis, dise.Sustainability rests on the principle that we must meet the needs of the present without compromising the ability of future generations to meet their own needs. Starving people in poor nations, obesity in rich nations, increasing food pric作者: 蠟燭 時(shí)間: 2025-3-24 10:33
K. V?h?kangas,O. Pelkonenes, e.g. climate change, energy crisis, economy crisis, dise.Sustainability rests on the principle that we must meet the needs of the present without compromising the ability of future generations to meet their own needs. Starving people in poor nations, obesity in rich nations, increasing food pric作者: BAIT 時(shí)間: 2025-3-24 13:38 作者: acolyte 時(shí)間: 2025-3-24 15:56
M. Curvall,E. Kazemi Vala own needs. Starving people in poor nations, obesity in rich nations, increasing food prices, on-going climate changes, increasing fuel and transportation costs, flaws of the global market, worldwide pesticide pollution, pest adaptation and resistance, loss of soil fertility and organic carbon, soil作者: 炸壞 時(shí)間: 2025-3-24 19:15 作者: 繼而發(fā)生 時(shí)間: 2025-3-25 02:28 作者: Intuitive 時(shí)間: 2025-3-25 05:39
S. Cholerton,N. W. McCracken,J. R. Idle own needs. Starving people in poor nations, obesity in rich nations, increasing food prices, on-going climate changes, increasing fuel and transportation costs, flaws of the global market, worldwide pesticide pollution, pest adaptation and resistance, loss of soil fertility and organic carbon, soil作者: BUMP 時(shí)間: 2025-3-25 07:41
S. L. Schwartz,M. R. Gastonguay,D. E. Robinson,N. J. Balteres, e.g. climate change, energy crisis, economy crisis, dise.Sustainability rests on the principle that we must meet the needs of the present without compromising the ability of future generations to meet their own needs. Starving people in poor nations, obesity in rich nations, increasing food pric作者: Lyme-disease 時(shí)間: 2025-3-25 13:46
J. Wahren,J. Gabrielsson,M. Curvall,E. Kazemi Vala own needs. Starving people in poor nations, obesity in rich nations, increasing food prices, on-going climate changes, increasing fuel and transportation costs, flaws of the global market, worldwide pesticide pollution, pest adaptation and resistance, loss of soil fertility and organic carbon, soil作者: affluent 時(shí)間: 2025-3-25 17:50
es, e.g. climate change, energy crisis, economy crisis, dise.Sustainability rests on the principle that we must meet the needs of the present without compromising the ability of future generations to meet their own needs. Starving people in poor nations, obesity in rich nations, increasing food pric作者: 飛鏢 時(shí)間: 2025-3-25 22:20
Biosynthesis and metabolism of nicotine and related alkaloids,es the use of tobacco products pleasurable. Nicotine and other alkaloids in .. have been ascribed many functions, i.e.and consequently they appear to be important to the evolution of the genus as it is known today. However, as important as . alkaloids are in eliciting animal responses from the utili作者: Digest 時(shí)間: 2025-3-26 03:54
The mammalian metabolism of nicotine: an overview,be associated with the pharmacological effects of alkaloids present in tobacco and transferred via tobacco smoke to the lung and the buccal and nasal epithelium where they are absorbed. In addition to the pleasure people gain from tobacco use it is undoubtedly associated with an increased health ris作者: Microgram 時(shí)間: 2025-3-26 05:58
The roles of cytochrome P450 in nicotine metabolism,a, 1988). To date, numerous studies have shown that cytochrome P450 is composed of many molecular forms and their expression is regulated by many factors such as drug administration, age, sex and pathophysiological conditions (Ryan and Levin, 1990; Soucek and Gut, 1992; Funae and Imaoka, 1992).作者: 加花粗鄙人 時(shí)間: 2025-3-26 11:31 作者: 柔軟 時(shí)間: 2025-3-26 15:42
N-Oxidation, N-methylation and N-conjugation reactions of nicotine,ternary ammonium product, which is usually more polar in nature and more water soluble than the parent base. In these reactions, the generation of a positively charged tetrahedral nitrogen centre represents a higher oxidation state, hence such metabolic transformations can be considered collectively作者: 乳汁 時(shí)間: 2025-3-26 17:16 作者: 保全 時(shí)間: 2025-3-27 00:50 作者: 尋找 時(shí)間: 2025-3-27 01:08 作者: Dawdle 時(shí)間: 2025-3-27 07:36
Kinetics of nicotine and its metabolites in animals,hly water soluble, strongly alkaline liquid with pKa of (-N=, -N <) 3.2 and 8.0, respectively. At physiological pH nicotine exists mainly in the form of the univalent nicotinium ion which appears, rather than the non-ionized base, to be the active form. Nicotine contains a chiral centre and is found作者: 宴會(huì) 時(shí)間: 2025-3-27 10:04 作者: 分離 時(shí)間: 2025-3-27 14:22
Sources of inter-individual variability in nicotine pharmacokinetics,though these responses are determined by many factors, to a certain extent the differences may be attributed to variation in the pharmacokinetics of nicotine, the major pharmacologically active component of tobacco.作者: Limerick 時(shí)間: 2025-3-27 20:05 作者: Dealing 時(shí)間: 2025-3-27 23:50
New methods for probing the disposition of nicotine in humans,eutical agent in the form of nicotine-containing chewing gum or nicotine preparations for transdermal absorption. The importance of nicotine in human physiology is related to its pleasurable effects as well as to its possible role in tobacco-related disorders. It may be assumed that, as with most ph作者: Lacerate 時(shí)間: 2025-3-28 05:29 作者: blithe 時(shí)間: 2025-3-28 07:26
The roles of cytochrome P450 in nicotine metabolism,a, 1988). To date, numerous studies have shown that cytochrome P450 is composed of many molecular forms and their expression is regulated by many factors such as drug administration, age, sex and pathophysiological conditions (Ryan and Levin, 1990; Soucek and Gut, 1992; Funae and Imaoka, 1992).作者: 剝皮 時(shí)間: 2025-3-28 11:50 作者: nostrum 時(shí)間: 2025-3-28 17:43 作者: Terminal 時(shí)間: 2025-3-28 19:57
https://doi.org/10.1007/978-94-011-2110-1Oxidation; absorption; alkaloids; enzyme; enzymes; kinetics; metabolism; methylation; pharmacokinetics; resea作者: 逃避系列單詞 時(shí)間: 2025-3-28 23:29
N-Oxidation, N-methylation and N-conjugation reactions of nicotine, of sp. hybridization on base strength, since as the ‘s’ character of an orbital increases, the electrons in that orbital are bound more tightly to the nucleus. In this respect, the regiospecificity of N-oxidation is an important consideration, especially as it relates to the structural and chemical作者: 侵蝕 時(shí)間: 2025-3-29 04:08 作者: 移植 時(shí)間: 2025-3-29 08:39
Physiologically based pharmacokinetic modelling of nicotine,PK approach and the availability of adequate computer hardware and software. In recent years, however, PBPK modelling has become a practical tool for the study of a variety of pharmacological and toxicological problems (Bischoff ., 1971; Gerlowski and Jain, 1983).作者: BUST 時(shí)間: 2025-3-29 14:03
New methods for probing the disposition of nicotine in humans,y and pharmacology of nicotine. It is noteworthy that literature is almost totally, devoid of information concerning the influence of disease on the pharmacokinetics of nicotine. Thus, data with regard to the influence of, e.g. liver disease or renal disease on nicotine disposal are not available bu作者: 運(yùn)氣 時(shí)間: 2025-3-29 17:10 作者: 鋪?zhàn)?nbsp; 時(shí)間: 2025-3-29 21:08 作者: Accede 時(shí)間: 2025-3-30 01:49
ainability challenges ofmajor agroecosystems in the developing and industrialized worlds. Theconcluding chapter discusses the design and implementation of sustainabledevelopment pathways, through the expression978-3-030-34601-0978-3-030-34599-0Series ISSN 2662-3889 Series E-ISSN 2662-3897 作者: 別炫耀 時(shí)間: 2025-3-30 06:56 作者: 烤架 時(shí)間: 2025-3-30 08:19 作者: inflate 時(shí)間: 2025-3-30 14:13 作者: 整體 時(shí)間: 2025-3-30 17:23
