標(biāo)題: Titlebook: Next Generation Kinase Inhibitors; Moving Beyond the AT Paul Shapiro Book 2020 Springer Nature Switzerland AG 2020 kinase inhibitors.ATP bi [打印本頁] 作者: FERN 時(shí)間: 2025-3-21 19:50
書目名稱Next Generation Kinase Inhibitors影響因子(影響力)
作者: 五行打油詩 時(shí)間: 2025-3-21 20:53 作者: 奴才 時(shí)間: 2025-3-22 01:41
Developing Kinase Inhibitors Using Computer-Aided Drug Design Approaches,ween their intrinsic properties with experimental activities, termed structure-activity relationship, information that can be used for optimization of known inhibitors in order to improve their activities. In this chapter, CADD protocols from both SBDD and LBDD will be presented along with real-life作者: DEI 時(shí)間: 2025-3-22 08:09 作者: Abduct 時(shí)間: 2025-3-22 10:48 作者: olfction 時(shí)間: 2025-3-22 16:47
Novel Peptide-Based Inhibitors of Protein Kinases,ve, modulators of protein kinase activity by virtue of their ability to mimic highly specific substrate-interaction domains of protein kinases. This chapter provides an overview of the development and application of novel peptide-based protein kinase inhibitors. The goal here is to highlight how the作者: Conduit 時(shí)間: 2025-3-22 18:27
Book 2020se inhibitor, there are only a few examples where these drugs provide sustained and durable patientresponses. The goal of this book is to provide biomedical scientists, graduate, and professional degree students insight into different approaches using small molecules to block specific protein kinase作者: MURKY 時(shí)間: 2025-3-22 23:51 作者: infantile 時(shí)間: 2025-3-23 04:10
Paul Shapiro,Ramon Martinez III,Amy Defnets serves as a key reference for scientists seeking a way toward greater control over the enormous power of the complex and vital immune system.978-1-4939-6163-4978-1-60761-869-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: miscreant 時(shí)間: 2025-3-23 06:46 作者: 設(shè)施 時(shí)間: 2025-3-23 10:16 作者: 裝入膠囊 時(shí)間: 2025-3-23 15:31
Amy Defnet,Ramon Martinez III,Paul Shapiros serves as a key reference for scientists seeking a way toward greater control over the enormous power of the complex and vital immune system.978-1-4939-6163-4978-1-60761-869-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: Eclampsia 時(shí)間: 2025-3-23 20:22
Wenbo Yu,David J. Weber,Paul Shapiro,Alexander D. MacKerell Jrs serves as a key reference for scientists seeking a way toward greater control over the enormous power of the complex and vital immune system.978-1-4939-6163-4978-1-60761-869-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: Pamphlet 時(shí)間: 2025-3-23 22:54
Rachel M. Sammons,Kevin N. Dalbys serves as a key reference for scientists seeking a way toward greater control over the enormous power of the complex and vital immune system.978-1-4939-6163-4978-1-60761-869-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: SPASM 時(shí)間: 2025-3-24 03:07 作者: 縮短 時(shí)間: 2025-3-24 06:59 作者: Malcontent 時(shí)間: 2025-3-24 10:52
e patientresponses. The goal of this book is to provide biomedical scientists, graduate, and professional degree students insight into different approaches using small molecules to block specific protein kinase978-3-030-48285-5978-3-030-48283-1作者: Acupressure 時(shí)間: 2025-3-24 18:47
id and a characteristic leopard spot fundus. Management of choroidal detachment is often targeted towards the underlying cause, with possible surgical management including drainage in haemorrhagic choroidal detachment and scleral decompression windows in UES.作者: TERRA 時(shí)間: 2025-3-24 19:51 作者: Surgeon 時(shí)間: 2025-3-25 01:52 作者: Evacuate 時(shí)間: 2025-3-25 04:46 作者: 戲法 時(shí)間: 2025-3-25 09:30
Protein Kinase Interactions with Regulatory and Effector Proteins,m plasma membrane receptors through the cell to cause changes in gene expression and cellular responses. This chapter will take a closer look at the interactions between protein kinases and their substrates and interacting partners. Despite the well-conserved organization of the ATP-binding and -cat作者: irradicable 時(shí)間: 2025-3-25 12:51
Developing Kinase Inhibitors Using Computer-Aided Drug Design Approaches, is an introduction of well-established and newly developed computer-aided drug design (CADD) approaches that are regularly being used in the development of kinase inhibitors. This includes methods from the two major CADD categories: structure-based drug design (SBDD) and ligand-based drug design (L作者: Hla461 時(shí)間: 2025-3-25 16:07 作者: 否決 時(shí)間: 2025-3-25 21:41
Novel Stabilized Peptide Inhibitors of Protein Kinases,ity among kinases within the additional flanking domains and sequences that may regulate processes such as catalytic function, substrate phosphorylation, or serve as regulatory domains. These other domains are often evolutionarily divergent across the kinase superfamily and provide unique handles fo作者: Corral 時(shí)間: 2025-3-26 00:55
Novel Peptide-Based Inhibitors of Protein Kinases,y aspects of cellular metabolism including signal transduction, transcription, translation, cell-cycle progression, and biosynthesis. Owing to their profound influence over such critical cellular processes, mutations or aberrant expression of protein kinases can have major implications on cell healt作者: 后來 時(shí)間: 2025-3-26 04:41 作者: incubus 時(shí)間: 2025-3-26 11:40
Paul Shapiro,Ramon Martinez III,Amy Defnetory protocols complete with lists of materials and vital notOver the past several years, a high diversity of regulatory cells and suppressive molecules has taken centre stage in the field of immunoregulation.In Suppression and Regulation of Immune Responses: Methods and Protocols, expert researchers作者: 琺瑯 時(shí)間: 2025-3-26 13:45 作者: 思想靈活 時(shí)間: 2025-3-26 20:18
Ramon Martinez III,Amy Defnet,Paul Shapiroory protocols complete with lists of materials and vital notOver the past several years, a high diversity of regulatory cells and suppressive molecules has taken centre stage in the field of immunoregulation.In Suppression and Regulation of Immune Responses: Methods and Protocols, expert researchers作者: Ligament 時(shí)間: 2025-3-26 23:15 作者: 知識分子 時(shí)間: 2025-3-27 03:22
Wenbo Yu,David J. Weber,Paul Shapiro,Alexander D. MacKerell Jrory protocols complete with lists of materials and vital notOver the past several years, a high diversity of regulatory cells and suppressive molecules has taken centre stage in the field of immunoregulation.In Suppression and Regulation of Immune Responses: Methods and Protocols, expert researchers作者: 禁止,切斷 時(shí)間: 2025-3-27 05:44 作者: Gorilla 時(shí)間: 2025-3-27 09:26 作者: 借喻 時(shí)間: 2025-3-27 15:04 作者: Expiration 時(shí)間: 2025-3-27 21:45 作者: Malleable 時(shí)間: 2025-3-27 23:04 作者: anthesis 時(shí)間: 2025-3-28 05:55 作者: 安撫 時(shí)間: 2025-3-28 08:42 作者: DUST 時(shí)間: 2025-3-28 10:41 作者: 甜食 時(shí)間: 2025-3-28 15:32 作者: 易受刺激 時(shí)間: 2025-3-28 20:14 作者: 造反,叛亂 時(shí)間: 2025-3-29 02:05
Introduction to Kinases, Cellular Signaling, and Kinase Inhibitors, pathways, and structural features will introduce current kinase inhibitor approaches and provide the rationale for identifying alternative approaches to block excess protein kinase activities that promote disease.