標(biāo)題: Titlebook: Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins; Ulf Grawunder,Stefan Barth Book 2017 Springer International Publishing A [打印本頁(yè)] 作者: 使委屈 時(shí)間: 2025-3-21 19:11
書(shū)目名稱(chēng)Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins影響因子(影響力)
書(shū)目名稱(chēng)Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱(chēng)Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱(chēng)Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins被引頻次
書(shū)目名稱(chēng)Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins被引頻次學(xué)科排名
書(shū)目名稱(chēng)Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins年度引用
書(shū)目名稱(chēng)Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins年度引用學(xué)科排名
書(shū)目名稱(chēng)Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins讀者反饋
書(shū)目名稱(chēng)Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins讀者反饋學(xué)科排名
作者: JADED 時(shí)間: 2025-3-21 21:05
Milestones in Drug Therapyhttp://image.papertrans.cn/n/image/666181.jpg作者: 輕快帶來(lái)危險(xiǎn) 時(shí)間: 2025-3-22 01:01
https://doi.org/10.1007/978-3-319-46877-8Antibody based cancer therapy; Antibody drug conjugates (ADC); Immunotoxin development; Pyrrolobenzodia作者: 郊外 時(shí)間: 2025-3-22 08:01 作者: 遠(yuǎn)足 時(shí)間: 2025-3-22 11:37 作者: Epidural-Space 時(shí)間: 2025-3-22 13:41
Chemical Assembly of Antibody-Drug Conjugates, over 60 are in clinical trials. Although many ADCs involve non-specific drug attachment via lysine and cysteine residues, the desire to produce homogeneous ADCs has led to the development of several site-specific chemical assembly strategies. The first site-specific ADCs are just beginning to enter作者: 變形詞 時(shí)間: 2025-3-22 19:14 作者: inflate 時(shí)間: 2025-3-22 23:48
Stable and Homogeneous Drug Conjugation by Sequential Bis-Alkylation at Disulphide Bonds Using Bis-ion in ADC development is that much effort and time is needed to fully optimise the combination of antibody, linker and drug. New linker strategies are required to ensure that more homogeneous and stable ADCs can be produced with more predictable in vivo behaviour without the need for extensive re-o作者: Facilities 時(shí)間: 2025-3-23 03:14 作者: 巨大沒(méi)有 時(shí)間: 2025-3-23 08:49 作者: VALID 時(shí)間: 2025-3-23 13:41
,Substance P–Saporin for the Treatment of Intractable Pain,ly links a biological toxin (SAP) and an endogenous peptide (SP) that targets that toxin to the subset of neurons expressing the NK1 receptor. SP-SAP, currently in phase I clinical trials, is unique as the only targeted toxin for pain to undergo human testing. We review the history of SP-SAP and rel作者: champaign 時(shí)間: 2025-3-23 13:51
Recombinant Immunotoxins for Chronic Inflammatory Disease,c inflammatory disorders like atopic dermatitis, rheumatoid arthritis, and diabetic ulcers, as many of these are strongly age related. There is thus an increasing demand to develop better therapeutic strategies to manage and cure chronic diseases. In many of these diseases, the trigger for onset of 作者: 騎師 時(shí)間: 2025-3-23 18:42
BL22: A Milestone in Targeting CD22,xotoxin. The antibody fragment that binds to the target cell is internalized along with the toxin, and the toxin fragment is transported to the cytosol where it catalytically kills the cell. Preclinical development showed significant cytotoxicity and antitumor activity toward CD22+ leukemia and lymp作者: 人充滿活力 時(shí)間: 2025-3-23 23:04 作者: BAN 時(shí)間: 2025-3-24 04:09 作者: 行業(yè) 時(shí)間: 2025-3-24 08:04 作者: BUCK 時(shí)間: 2025-3-24 11:12 作者: Muscularis 時(shí)間: 2025-3-24 16:03
2296-6056 will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology..978-3-319-83609-6978-3-319-46877-8Series ISSN 2296-6056 Series E-ISSN 2296-6064 作者: FECK 時(shí)間: 2025-3-24 20:28 作者: 雪白 時(shí)間: 2025-3-25 00:24 作者: KIN 時(shí)間: 2025-3-25 07:15 作者: chastise 時(shí)間: 2025-3-25 10:55 作者: 閹割 時(shí)間: 2025-3-25 15:19
Stable and Homogeneous Drug Conjugation by Sequential Bis-Alkylation at Disulphide Bonds Using Bis- disulphide bond in antibodies and antibody fragments. We have demonstrated that the bis-sulphone-derived conjugates retain antigen-binding, are stable in serum and exhibit potent and antigen-selective cell killing in both in vitro and in vivo cancer models. Disulphide re-bridging conjugation is a g作者: agglomerate 時(shí)間: 2025-3-25 19:28
Calicheamicin Antibody-Drug Conjugates for Liquid and Solid Tumor Indications,evelopment, including the ADC, inotuzumab ozogamicin, targeting CD22-positive, liquid tumors including NHL and ALL, and the CD33-targeting gemtuzumab ozogamicin, targeting AML..The recent expansion of the utility of calicheamicin conjugates to solid tumors may have a broader impact on ADC developmen作者: 含糊 時(shí)間: 2025-3-25 23:59
Enzyme-Based Strategies to Generate Site-Specifically Conjugated Antibody Drug Conjugates,C brentuximab vedotin (Adcetris.) and the anti-HER-2 ADC trastuzumab-emtansine (Kadcyla.), are approved for cancer therapy. In fact, Kadcyla. is only approved as a second-line therapy in breast cancer due to a limited clinical benefit in comparison to standard therapy as a first-line therapy. There 作者: 高興去去 時(shí)間: 2025-3-26 00:19 作者: 裂縫 時(shí)間: 2025-3-26 05:27 作者: debble 時(shí)間: 2025-3-26 11:46 作者: machination 時(shí)間: 2025-3-26 16:27 作者: 比賽用背帶 時(shí)間: 2025-3-26 19:45 作者: obsession 時(shí)間: 2025-3-26 21:12 作者: BIDE 時(shí)間: 2025-3-27 04:07
GRIGRI: Gesture Recognition on Interactive Graphical Radar Image,commands and values. To evaluate the usability and problems of such a HMI, we have experimented GRIGRI with controllers. We present results of recognition, input time and controller feelings. The experiment demonstrates the real advantages of GRIGRI compared to mouse based HMI and also its current l作者: finite 時(shí)間: 2025-3-27 06:37 作者: 切掉 時(shí)間: 2025-3-27 12:43 作者: 謙虛的人 時(shí)間: 2025-3-27 17:25 作者: Vital-Signs 時(shí)間: 2025-3-27 21:45
Einflu? von Talniederungen auf die diffusen Stoffeintr?ge in Kleingew?sser über den Grundwasserpfadologischen und hydrochemischen Prozesse bekannt sind (Blicher-Mathiesen 1998), fehlt es noch immer an gebietsrepr?sentativen validen Kennwerten und Modellen, die die reale Puffer- und Retentionsfunktion von unterschiedlich intensiv entw?sserten und genutzten Talniederungen beschreiben (Hoffmann 1998).作者: 臥虎藏龍 時(shí)間: 2025-3-27 22:38
pRAM: The Probabilistic RAM Neural Processorvascular disease and should be used to distinguish patients with pulmonary arterial hypertension from patients with pulmonary hypertension associated with left heart failure or chronic thromboembolic pulmonary hypertension.作者: Optometrist 時(shí)間: 2025-3-28 03:42
his assertion that more complex ecosystems are more stable. His examples seem highly heterogeneous in the light of twenty years of hindsight. They contain, for example, comments on the cyclical behaviour of single-species population models, a statement that tropical systems are free from pest outbre作者: Microaneurysm 時(shí)間: 2025-3-28 08:45 作者: CAND 時(shí)間: 2025-3-28 12:01
Jamilah Meghji,Onn Min Konscrete Element Method (CFD-DEM) model are provided.?.Modeling and Simulation of Fluidized Bed Reactors for Chemical Looping Combustion.?will be an invaluable reference for industry practitioners and researchers978-3-031-11337-6978-3-031-11335-2作者: 六個(gè)才偏離 時(shí)間: 2025-3-28 15:47 作者: insecticide 時(shí)間: 2025-3-28 21:55 作者: 旋轉(zhuǎn)一周 時(shí)間: 2025-3-29 01:37
Intimacy: Nicholas Faunt, Faith and the Consolations of Friendship,n and sweet remembraunce of you’, until his return home would permit ‘more free possessing of eche other’. It was an ardent and exclusive statement of affection that used the language of revered male friendship. These conventions—manifestations of the early modern ‘culture of epistolarity’ and the f