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標題: Titlebook: New Concepts in Depression; M. Briley,G. Fillion Textbook 1988Latest edition Macmillan Publishers Limited 1988 clinical research.depressio [打印本頁]

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作者: Nmda-Receptor    時間: 2025-3-21 21:20
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https://doi.org/10.1007/978-1-349-09506-3clinical research; depression; pharmacology; research
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Primary Cultures of Monoaminergic Neurons as a Prospective Tool in Neuropharmacology,Primary cultures of central nervous system neurons have been extensively used as a convenient model in the field of developmental neurobiology (Privat .., 1979). In addition, they provide a simplified model whose environment can be totally controlled and which allows for pharmacological manipulations of living cells.
作者: 簡略    時間: 2025-3-22 22:28
Neuropharmacological Adaptive Effects in the Actions of Antidepressant Drugs, ECT and Lithium,cal improvement (Oswald .., 1972). However, there is an increasing feeling that this may be an over-simplification. Depression is a complex illness with many facets of which mood is only one. Overall rating scales may be a blunt instrument for detecting improvements in a multi-symptomatic state. The
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Thyrotrophin-realeasing Hormone (TRH) and 5-Hydroxytryptamine (5-HT) Interactions and Their Involver number and responsiveness. Furthermore, the down-regulation of β-adrenocep-tors produced by antidepressant treatments is dependent upon intact 5-HT neurones. There is, however, little information about the factors involved in the regulation of 5-HT receptor function. This chapter investigates the
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Lithium Augmentation of Antidepressant Treatments: Evidence for the Involvement of the 5-HT System?posed for treatment-resistant depression: reserpine (Poldinger, 1963; Ha?kovec and Rysánek, 1967; Hopkinson and Kenny, 1975; Zohar .., 1987), T. (Earle, 1969; Ogura .., 1974; Banki, 1977; Goodwin .., 1982), psychostimulants (Wharton ., 1971; Ayd and Zohar, 1987), oestrogen supplementation (Shapira .
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,Central and Peripheral Effects of CH-38083: a New α2-Antagonist,a selective antagonist of monoamine oxidase A (MAO-A) (Cohen .., 1982). Desipramine (DMI) produces a short-lasting decrease in the sedation response to α-agonists (Heal .., 1983). The functional response of sedation may involve presynaptic α.-adrenoceptors (see Green and Nutt, 1985): thus DMI exerts
作者: 嗎啡    時間: 2025-3-25 11:10
Contributions from Peripheral Autonomic Pharmacology to an Understanding of Antidepressant Drug Actiprindole, which are not known to directly affect noradrenergic or serotonergic neurons. The clinical effectiveness of agents such as maprotiline and nisoxetine (Iversen and Mackay, 1979), which selectively inhibit neuronal uptake of noradrenaline, points to the importance of the noradrenergic neuro
作者: 粘連    時間: 2025-3-25 15:07
Effects of the Membrane-active Antidepressant Drugs, Selective 5-HT or NA Uptake Inhibitors, on ,-C or blockers of 5-HT synthesis, but also by membrane-active drugs such as the antidepressants clomipramine, citalopram and zimelidine which are potent 5 HT uptake inhibitors (Frey, 1975; Paw?owski .., 1980; Paw?owski, 1981). Since clomipramine and citalopram do not prevent the hyperthermia induced b
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A. Coppen,C. Swadecontemporary global culture. In doing this, it has also been shown how unsatisfactory these assumptions are in terms of their logic and their adequacy. Most of them contain logical inconsistencies and all are inadequate in that they do not provide plausible explanations of major features of common e
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W. R. Buckett,G. P. Luscombe,P. C. Thomasve thrived using these strategies.Show how firms can develop.This book gives an indispensable guide to navigating the shift in customer behavior and discovers how to rally their resources, cultivate capabilities, and forge strategies that harness cutting-edge technologies. In today‘s tech-centric wo
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A. Stenger,C. Palmier,M. Brileyles can contribute to overcome memorization and the fragmentation of knowledge by postulating network and critical thinking, student orientation and environmental action. I argue that the development of critical consciousness (Freire .) through the promotion of argumentation skills is one important
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B. Suranyi-Cadotte,S. Gauthier,F. Lafaille,S. DeFlores,T. V. Dam,N. P. V. Nair,R. Quirionor thought for metaphysics. And the fruitfulness of their project seemed to vindicate their hurry. In all this, there is a lesson for us today; we are embarking on a fresh speculative enterprise, and it behoves us to try to understand and avoid the sort of mistakes they made.
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J. Laval,A. Stenger,M. Brileylar perspectives on geography education and the role of ESD. These findings suggest that there is a need for strengthening teacher’s agency and a more open framing of textbooks for transformative pedagogic practice as inspired by ESD.
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W. R. Buckett,G. P. Luscombe,P. C. Thomasnd resources to reshape marketing strategies, this book is the essential read. Executives climbing the corporate ladder will find it a compass, unraveling how new age technologies dance with both traditional an978-3-031-59636-0978-3-031-59637-7Series ISSN 2731-5614 Series E-ISSN 2731-5622
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G. Fillion,S. Dufois,C. Fayolle,M. P. Fillion,P. Oudar,P. Barone
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L. Marlier,F. Finiels-Marlier,P. Poulat,N. Koenig,M.-J. Drian,A. Privat
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Beyond Nosology in Biological Psychiatry. 5-HT Disturbances in Mood, Aggression and Anxiety Disordeecific. Van K?mmen (1987) called 5-HT, ironically, a neurotransmitter of all seasons. We do not concur with either statement and in this chapter we explain why. First we discuss the available data; then we try to bring them into a conceptual framework.
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Lithium Augmentation of Antidepressant Treatments: Evidence for the Involvement of the 5-HT System?tment of choice for resistant depression (Medical Research Council, 1965; Davidson .., 1978). British investigators have recently advanced that lithium addition might soon supersede the use of ECT in treatment-resistant depression (Pai .., 1986).
作者: 不能根除    時間: 2025-3-31 21:35
,Is Down-regulation of β-Adrenoceptors Necessary for Antidepressant Activity?,s of these compounds are not usually seen until after 2 to 3 weeks of continual treatment. Additionally, so-called ‘a(chǎn)typical’ antidepressants such as mianserin and iprindole appear not to inhibit the metabolism or reuptake of monoamines (see Stone, 1983).
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Neuropharmacological Adaptive Effects in the Actions of Antidepressant Drugs, ECT and Lithium,re are hints in the literature that the response of certain symptoms to antidepressants may occur within a few days. There are also confounding factors: for example, some antidepressants, e.g. amitriptyline, are sedative and may improve sleep early, so altering responses as judged by rating scales.
作者: 一大群    時間: 2025-4-1 08:10
, Identification of the Serotonin (5-HT) Autoreceptor in the Rat Suprachiasmatic Nucleus (SCN), as they observed, circadian rhythms of depressives are phase-advanced compared with control subjects, one might expect an early escape since the drug will have been given later in the circadian cycle of the depressives.
作者: Meander    時間: 2025-4-1 10:10
Textbook 1988Latest editionions of the major preclinical and clinical researchers in the field of depression. In addition, a number of chapters concentrate on clinical or physiological phenomena associated with depression. The general attitude of the book is one of openness to new ideas several of which are presented here for
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Molecular Interactions of Antidepressants with the Serotonergic Receptor 5-HT1D Coupled to a High-aed to a deficit in those amines, and, in particular, may involve 5-HT metabolite disturbances (Coppen, 1967; Murphy .., 1978; van Praag, 1982). However, Crow .. (1984) did not observe any changes in serotonin metabolites in individuals committing suicide.
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Pretreatment by DSP4 Fails to Reduce the Effectiveness of Desipramine in Blocking Tetrabenazine-ind and β-adrenoceptors have been shown to be involved in the antagonism, by desipramine, of apomorphine-induced hypothermia (Paw?owski and Mazela, 1986) and tetrabenazine-induced effects (Laval .., 1988).
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