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標(biāo)題: Titlebook: New Approaches for Antifungal Drugs; Prabhavathi B. Fernandes Book 1992 Springer Science+Business Media New York 1992 drugs.pharmaceutical [打印本頁]

作者: implicate    時間: 2025-3-21 17:35
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作者: Root494    時間: 2025-3-21 23:45
John E. McCulloughe ein antibolschewistisches Weltbild pflegten. Ich erinnere mich nur zu genau an eine Auseinandersetzung mit dem Deutschlehrer in der Obersekunda über ., den ich neben . besonders sch?tzte und deshalb verteidigte, was allein mir das Etikett ?fanatisch“ einbrachte.
作者: TOXIC    時間: 2025-3-22 03:23

作者: ZEST    時間: 2025-3-22 04:39
Toshikazu Oking asymptotisch an. - Nach jeder Stufe ist ggf. die Umlagerung der Druckkr?fte (und Auflagerkr?fte) infolge der Verformungen zu berechnen; das ist bei verschieblichen Systemen i.allg. immer erforderlich. Bei praktischen Berechnungen genügen vielfach wenige Iterationsstufen, manchmal nur eine. Zudem
作者: 保存    時間: 2025-3-22 12:32
Jessica A. Gormane indicated for treatment of patients with established atherosclerotic disease or inherited hypercholesterolemia who have not achieved their desired low-density lipoprotein cholesterol (LDL-C) level despite maximally tolerated statin and ezetimibe therapy. PCSK-9 inhibitors are now the preferred age
作者: 不自然    時間: 2025-3-22 16:19
S. L. Kelly,M. A. Quail,J. Rowe,D. E. Kelly?providing a bridge for theory through the “reduce-or-retreat” framework, this monograph extends and broadens the traditional convergence analyses in several ways. Levy develops a generalized notion of approaching stationarity which applies to non-smooth objectives, and explores the roles of the des
作者: gospel    時間: 2025-3-22 17:19
Junius M. Clark?providing a bridge for theory through the “reduce-or-retreat” framework, this monograph extends and broadens the traditional convergence analyses in several ways. Levy develops a generalized notion of approaching stationarity which applies to non-smooth objectives, and explores the roles of the des
作者: Obverse    時間: 2025-3-22 22:11
The Need for New Antifungal Drugs,e mycoses. Both localized and disseminated infections occur almost exclusively in immunosuppressed hosts. While the source and nature of the immunosuppression impact on the susceptibility of the host to specific opportunistic infections (OI), disseminated fungal infections are among the most common
作者: 不遵守    時間: 2025-3-23 01:28
,(1→6)—,-Glucan Biosynthesis: Potential Targets for Antifungal Drugs,me 3% of the dry weight of the yeast cell. The so-called (1→6)- .-D-glucan is a mixed-linked polymer of approximately 140 to 200 glucose residues that are principally joined through linear (1?6)-.-linkages (Manners et al., 1973b; Boone et al., 1990), but also contain some linear (1→3)linked residues
作者: 燦爛    時間: 2025-3-23 06:12
Importance of Chitin Synthesis for Fungal Growth and as a Target for Antifungal Agents, a target for antifungal chemotherapy, this chapter reviews the current understanding of the mode of action of the polyoxins and nikkomycins and the genetics of chitin synthesis in . that pertain to the question of the requirement for chitin for fungal growth. The evidence obtained from this work st
作者: 不愿    時間: 2025-3-23 13:35
Pradimicin, A Novel Antifungal Agent,eliorate their side effects. There is, therefore, a need for a safe and fungal-selective agent for the treatment of life-threatening infections, which we anticipate would even be greater in the future.
作者: Mere僅僅    時間: 2025-3-23 14:06

作者: 內(nèi)閣    時間: 2025-3-23 18:05
Genetic Approaches to Antifungal Drug Discovery,echanisms of pathogenesis, the basis of resistance to antifungal toxins, and the biosynthesis of factors associated with virulence are being investigated by genetic methodologies. Considerable progress has been made in the molecular analysis of the opportunistic human pathogen . and related species
作者: palliate    時間: 2025-3-24 00:14
Claude P. Selitrennikoff,Alison J. Vigers,Walden K. Roberts
作者: 慢跑鞋    時間: 2025-3-24 06:03
http://image.papertrans.cn/n/image/664781.jpg
作者: adjacent    時間: 2025-3-24 07:25
https://doi.org/10.1007/978-1-4899-6729-9drugs; pharmaceutical science; research
作者: 牢騷    時間: 2025-3-24 12:43
978-1-4899-6731-2Springer Science+Business Media New York 1992
作者: jettison    時間: 2025-3-24 17:04

作者: 兇猛    時間: 2025-3-24 19:56
H. Bussey,C. Boone,J. Brown,K. Hill,T. Roemer,A-M Sdicuig . (wieder) gegründete Universit?t verstand sich — die Professoren der katholischen Fakult?t, wie die sp?teren Bisch?fe . und ., eingeschlossen — als intellektuelle Enklave in einer katholischen Provinz, in der eine biederm?nnische Kaufmannsgesellschaft den Ton angab. Die antikatholische Sozialisa
作者: Benign    時間: 2025-3-25 00:08

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作者: 收集    時間: 2025-3-25 10:59

作者: Fantasy    時間: 2025-3-25 15:01

作者: Modify    時間: 2025-3-25 16:09

作者: 令人作嘔    時間: 2025-3-25 21:00

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作者: follicular-unit    時間: 2025-3-26 05:00

作者: 修飾語    時間: 2025-3-26 10:18
Importance of Chitin Synthesis for Fungal Growth and as a Target for Antifungal Agents,one, 1986), Natural product inhibitors of chitin synthesis, the polyoxins and the nikkomycins, have been found that inhibit the growth of fungi (Bowers et al., 1974; Dahn et al., 1976; Hagenmaier et al., 1979; Isono et al., 1967, 1969). However, both the fact that these agents have not proven to be
作者: 赦免    時間: 2025-3-26 16:08
,The Fungal Cell Wall — A Target For Lipopeptide Antifungal Agents,tifungal therapy, especially for life-threatening disseminated fungal infections, is not satisfactory because of limited efficacy and/or toxicity (Graybill, 1989). Second, there is an increased incidence of fungal infections attributed to the aggressive use of cancer chemotherapy, organ transplantat
作者: 大約冬季    時間: 2025-3-26 20:04
Pradimicin, A Novel Antifungal Agent, they do not normally cause infections because the host immune system protects against them. However, the number of patients who are severely immunocompromised by acquired immunodeficiency syndrome (AIDS), organ and bone marrow transplantations, and cancer chemotherapy has rapidly increased recently
作者: 金絲雀    時間: 2025-3-26 23:11
Antifungal Proteins from Plants: A Possible New Source of Human Therapeutics,ons is that fungi and their eukaryotic hosts are surprisingly similar. One of the main tenants of chemotherapy and drug discovery groups is to exploit a biochemical difference between the host and the pathogen. Several drugs currently in use capitalize on differences in membrane sterols (polyene ant
作者: Gudgeon    時間: 2025-3-27 03:13
,Elongation Factor 3 — A Unique Fungal Protein,y in the fungal family. The translational machinery of yeast is nonfunctional without this protein. A physical analog of EF-3 is absent in higher eukaryotes. Extensive knowledge of the structure and function of this unique yeast protein and comparative structural analyses of EF-3 with other eukaryot
作者: insomnia    時間: 2025-3-27 08:50
Genetic Approaches to Antifungal Drug Discovery,s aspects of the biology and genetic regulation of cellular processes in these lower eukaryotes. The cloning and analysis of genes and their products has led to a large body of data that allows comparison of key molecules in fungi with their counterparts in vertebrate species. To a great extent, a s
作者: 實(shí)現(xiàn)    時間: 2025-3-27 10:17
Sterol 14,-Demethylase: Target of the Azole Antifungal Agents,to be potent inhibitors of a wide variety of fungi that have membrane sterols. However, a number of challenges remain as novel fungal infections occur in immunocompromised patients and with the occurrence of disease resistance. The latter is currently more pronounced as a problem in agriculture, but
作者: Anthropoid    時間: 2025-3-27 17:27

作者: 熄滅    時間: 2025-3-27 17:53
Sterol 14,-Demethylase: Target of the Azole Antifungal Agents,e of the azole antifungals has been apparent for more than 20 years the molecular details of tolerance and mode of action are only now becoming clearly defined. Many of these phenomena are now amenable to modern molecular analysis and should allow these studies to be completed.
作者: 六個才偏離    時間: 2025-3-27 23:56
Amphotericin B Phospholipid Formulations,g, and hypotension have been reported to occur during infusion of the drug while chronic effects such as renal toxicity, hypokalemia, and hypomagnesemia have been reported (Cheng et al., 1982; Lopez-Berestein et al., 1987).
作者: 壓艙物    時間: 2025-3-28 03:22

作者: iodides    時間: 2025-3-28 08:27

作者: facetious    時間: 2025-3-28 11:25

作者: 流浪者    時間: 2025-3-28 17:23
Michel Janssen,Jürgen Rennution, their toxicity has been studied more thoroughly. The organoborons, including the carboranes, which are used mainly in the laboratory, range from slightly toxic to very toxic. The toxic mechanism is more or less known for several groups of boron compounds. The following chapters give the exper
作者: 女歌星    時間: 2025-3-28 22:46

作者: 細(xì)菌等    時間: 2025-3-29 01:15
like reading manuals but who still liketo learn logic synthesis as practised in the real world. The primaryfocus of the book is .Synopsys Design Compiler?:. the leadingsynthesis tool in the EDA marketplace. The book is specially organizedto assist designers accustomed to schematic capture based desi




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