作者: 侵略 時間: 2025-3-21 20:35 作者: FORGO 時間: 2025-3-22 04:16 作者: ATOPY 時間: 2025-3-22 08:38 作者: 較早 時間: 2025-3-22 09:22 作者: COUCH 時間: 2025-3-22 14:06
The Retinal TNAPwell as diseases of the nervous system. Exploration of TNAP in well characterized neural circuits such as the retina, might significantly advance our understanding regarding neural TNAP’s roles. This chapter reviews the scarce literature as well as our findings on retinal TNAP. We found that retinal作者: dominant 時間: 2025-3-22 18:52
Tissue Non-specific Alkaline Phosphatase (TNAP) in Vessels of the Brainange (20?m.) between the blood and the parenchyma of brain. Under influence of surrounding tissues, the brain microvessel endothelium expresses a specific phenotype that regulates and restricts the entry of compounds and cells from blood to brain, and defined the so-called blood–brain barrier (BBB).作者: 畏縮 時間: 2025-3-23 01:07 作者: NEXUS 時間: 2025-3-23 03:28
TNAP, an Essential Player in Membrane Lipid Rafts of Neuronal Cellsand is expressed in different tissues. As the other members of the ecto-phosphatase family, TNAP is targeted to membrane lipid rafts. Such micro domains enriched in particular lipids, are involved in cell sorting, are in close contact with the cellular cytoskeleton and play the role of signaling pla作者: canvass 時間: 2025-3-23 05:55
Signal Transduction Pathways of TNAP: Molecular Network Analysese epilepsy and Alzheimer’s disease, our understanding about the role of TNAP in the regulation of neurotransmission is severely limited. The aim of our study was to integrate the fragmented knowledge into a comprehensive view regarding neuronal functions of TNAP using objective tools. As a model we 作者: mediocrity 時間: 2025-3-23 11:43
Vitamin B-6 Metabolism and Interactions with TNAPccurrence of pyridoxine responsive seizures in hypophosphatasia. The increase in plasma pyridoxal phosphate indicates the importance of tissue non-specific alkaline phosphatase (TNAP) in transferring vitamin B-6 into the tissues. Vitamin B-6 is involved in the biosynthesis of most of the neurotransm作者: Rankle 時間: 2025-3-23 14:11 作者: Interferons 時間: 2025-3-23 20:42 作者: 補角 時間: 2025-3-24 01:01
Neurological Symptoms of Hypophosphatasiaonspecific alkaline phosphatase (TNAP). This disease is characterized by disrupted bone and tooth mineralization, and reduced serum AP activity. Along with bone and tooth symptoms, many neurological symptoms, seizure, encephalopathy, intracranial hypertension, mental retardation, deafness, and growt作者: Cardiac-Output 時間: 2025-3-24 02:41 作者: 拾落穗 時間: 2025-3-24 07:40
Jean Pierre Sallesve, because we tend to think of speed as perhaps . quintessential marker of modernity and modernism. The introduction reviews the history of discussions of speed, and speed studies as an emerging discipline in the work of Paul Virilio and others. Then it describes the “early modern speedscape”: earl作者: 口訣 時間: 2025-3-24 14:20 作者: Gastric 時間: 2025-3-24 14:59
Sonoko Narisawang with a systematic study of speed of sound in various medi.This book focuses on two related topics in fluid mechanics, that is, speed of sound through various media and critical flow associated with gas–liquid flows. The first part of the book explores the speed of sound in liquids, gases, and sol作者: Obstreperous 時間: 2025-3-24 20:29 作者: 我要威脅 時間: 2025-3-25 01:11
Herbert Zimmermann,David Langer. Das Prozedere der Entwicklung, Serienreifmachung und Markteinführung einer neuen Kühlschrank-Generation unterscheidet sich zum Beispiel nur wenig von dem des Vorg?ngers. Hier setzt die Standardisierung an. Sie will Innovationen mit Wiederhol-Charakter identifizieren, die Parallelen herausarbeiten 作者: 積習難改 時間: 2025-3-25 04:21 作者: Salivary-Gland 時間: 2025-3-25 09:08
Orsolya Kántor,Dorottya Cserpán,Béla V?lgyi,ákos Lukáts,Zoltán Somogyvári. Das Prozedere der Entwicklung, Serienreifmachung und Markteinführung einer neuen Kühlschrank-Generation unterscheidet sich zum Beispiel nur wenig von dem des Vorg?ngers. Hier setzt die Standardisierung an. Sie will Innovationen mit Wiederhol-Charakter identifizieren, die Parallelen herausarbeiten 作者: 貧窮地活 時間: 2025-3-25 11:47 作者: indecipherable 時間: 2025-3-25 17:14 作者: 撫育 時間: 2025-3-25 22:35
László Négyessy,Balázs Gy?rffy,János Hanics,Mihály Bányai,Caroline Fonta,Fül?p Bazsóitie. Bovendien gaat monddroogte het dagelijks leven domineren, omdat zaken als eten en praten plotseling niet meer vanzelfsprekend zijn.?.Deze geheel herziene uitgave van .Speeksel, speekselklieren en mondgezondheid. biedt een integraal overzicht van speeksel, vanaf de vorming in de speekselklieren作者: 不利 時間: 2025-3-26 04:12
Stephen P. Coburneuw beeldmateriaal.Zowel geschikt voor de student als de erv.Speeksel is van essentieel belang voor onze mondgezondheid. Zonder speeksel vallen tanden en kiezen ten prooi aan afbraak door cari?s, erosie en attritie. Bovendien gaat monddroogte het dagelijks leven domineren, omdat zaken als eten en pr作者: Ovulation 時間: 2025-3-26 04:22 作者: 危險 時間: 2025-3-26 10:56 作者: Allowance 時間: 2025-3-26 14:21
itie. Bovendien gaat monddroogte het dagelijks leven domineren, omdat zaken als eten en praten plotseling niet meer vanzelfsprekend zijn.?.Deze geheel herziene uitgave van .Speeksel, speekselklieren en mondgezondheid. biedt een integraal overzicht van speeksel, vanaf de vorming in de speekselklieren作者: 軌道 時間: 2025-3-26 20:35 作者: 斜坡 時間: 2025-3-26 23:23
Christine Hofmann,Franz Jakob,Lothar Seefried,Birgit Mentrup,Stephanie Graser,Horacio Plotkin,HermanMG-2-)mucine. MUC5B is afkomstig uit alle (sero)mukeuze speekselklieren. MUC7 lijkt niet in alle personen aanwezig te zijn in palatinaal speeksel. Beide soorten mucinen verschillen in biochemische eigenschappen en hebben waarschijnlijk verschillende functies..MUC5B is verantwoordelijk voor de visco-作者: saphenous-vein 時間: 2025-3-27 01:49
0306-0225 eural functions.A valuable resource for both researchers andPhosphatases, such as TNAP are fundamental in regulating the roles of cellular, and consequently numerous body functions. TNAP is a ubiquitous enzyme with a wide spectrum of substrates and specificity. Regulation at the cellular level and t作者: KIN 時間: 2025-3-27 07:26 作者: FAZE 時間: 2025-3-27 12:59
Book 2015ex diseases such as epilepsy, developmental retardation and Alzheimer‘s disease. Available data suggest that, regarding brain functions, TNAP is a potentially important target of clinical research. This book aims to provide an overview of our current understanding of the functions of TNAP in the brain and on other tissues and organs.作者: rheumatology 時間: 2025-3-27 14:22
TNAP and Pain Controlous pronociceptive nucleotides like adenosine triphosphate (ATP) into the antinociceptive nucleoside adenosine. This chapter discusses the role of TNAP and other ectonucleotidases in nociceptive circuits, and their potential as future targets of new therapeutics to treat chronic pain.作者: Hippocampus 時間: 2025-3-27 18:23 作者: 狂熱文化 時間: 2025-3-28 00:09 作者: 傻 時間: 2025-3-28 03:05
Caroline Fonta,László NégyessyOffers a wealth of new information on alkaline phosphatase TNAP functions in the nervous system.Opens up new insights on the regulation of neural functions.A valuable resource for both researchers and作者: Cantankerous 時間: 2025-3-28 06:52 作者: 搖曳的微光 時間: 2025-3-28 11:56
Neuronal Tissue-Nonspecific Alkaline Phosphatase (TNAP)978-94-017-7197-9Series ISSN 0306-0225 Series E-ISSN 2542-8810 作者: Narcissist 時間: 2025-3-28 17:38
Clinical Forms and Animal Models of Hypophosphatasia, calcium and phosphorus are not decreased, resulting in hypercalciuria and nephrocalcinosis. Hypercalcemic crisis may occur. Failure to thrive and growth retardation are concerns. In infantile and adult forms of HPP, non-traumatic fractures may be the prominent manifestation, with otherwise unexpla作者: irritation 時間: 2025-3-28 19:36 作者: 關(guān)心 時間: 2025-3-29 02:19 作者: 向外 時間: 2025-3-29 07:02 作者: glomeruli 時間: 2025-3-29 09:31 作者: phase-2-enzyme 時間: 2025-3-29 12:40 作者: 創(chuàng)作 時間: 2025-3-29 15:46
Tissue Non-specific Alkaline Phosphatase (TNAP) in Vessels of the Braine in favour of an important role for TNAP in brain function. TNAP is thought to be responsible for the control of transport of some compounds across the plasma membrane of the BCECs. Here, we report that levamisole-mediated inhibition of TNAP provokes an increase of the permeability to Lucifer Yello作者: Hypopnea 時間: 2025-3-29 22:25
What Can We Learn About the Neural Functions of TNAP from Studies on Other Organs and Tissues?d in the dephosphorylation of the bacterial toxin lipopolysaccharide, all molecules known to be involved in inflammation. The role of TNAP in establishing the ATP/adenosine ratio is important for purinergic signaling, and these mechanisms could be significant in determining axonal growth in the brai作者: Self-Help-Group 時間: 2025-3-30 03:38 作者: 易改變 時間: 2025-3-30 05:49
Signal Transduction Pathways of TNAP: Molecular Network Analyses signal flow towards a subset of molecules. TNAP also appears as the source of signal to be spread via interactions with molecules involved among others in neurodegeneration. Cluster analyses identified TNAP as part of the second messenger signalling cascade. However, TNAP also forms connections wit作者: 莊嚴 時間: 2025-3-30 08:19
Vitamin B-6 Metabolism and Interactions with TNAPP clearly influences extracellular and intracellular metabolism of vitamin B-6 in brain, particularly during developmental stages. While effects on GABA metabolism appear to be the major contributor to seizures, multiple other intra- and extra-cellular metabolic systems may be affected directly and/作者: Crohns-disease 時間: 2025-3-30 15:55
Tetramisole and Levamisole Suppress Neuronal Activity Independently from Their Inhibitory Action on etramisole effects were not stereo-specific and they were not mimicked by another inhibitor of TNAP, MLS-0038949. The decrease of axonal conduction velocity and preliminary intracellular data suggest that tetramisole blocks voltage-dependent sodium channels. Our results imply that levamisole or tetr作者: maudtin 時間: 2025-3-30 17:08 作者: LIMIT 時間: 2025-3-30 21:30
Recombinant Enzyme Replacement Therapy in Hypophosphatasia unclear whether ERT also has beneficial effects for craniosynostosis and in other affected tissues in HPP such as brain and kidney. Long-term data are not yet available and further systematic clinical trials are needed. It is also necessary to establish therapeutic approaches to help patients who a作者: 手榴彈 時間: 2025-3-31 04:05 作者: mortuary 時間: 2025-3-31 08:14 作者: 赦免 時間: 2025-3-31 12:47
Etienne Mornetrgues, inherits Marlowe’s fascination with speed, but diversifies it into different forms and genres. The project of the book intersects with some existing work on Shakespeare, notably on Shakespeare and time and Shakespeare and performance, even while exploring a new idea of Shakespeare’s aesthetic
