標(biāo)題: Titlebook: Neurodegenerative Disorders: Loss of Function Through Gain of Function; Konrad Beyreuther,Yves Christen,Colin L. Masters Conference procee [打印本頁] 作者: 輕佻 時間: 2025-3-21 20:09
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書目名稱Neurodegenerative Disorders: Loss of Function Through Gain of Function影響因子(影響力)學(xué)科排名
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書目名稱Neurodegenerative Disorders: Loss of Function Through Gain of Function網(wǎng)絡(luò)公開度學(xué)科排名
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書目名稱Neurodegenerative Disorders: Loss of Function Through Gain of Function讀者反饋
書目名稱Neurodegenerative Disorders: Loss of Function Through Gain of Function讀者反饋學(xué)科排名
作者: 溝通 時間: 2025-3-21 23:39
https://doi.org/10.1007/978-3-662-04399-8Alzheimer; Alzheimer‘s Disease; Huntingdon‘s Disease; amyloid precursor protein; amyotrophic lateral scl作者: 無思維能力 時間: 2025-3-22 01:30
978-3-642-07448-6Springer-Verlag Berlin Heidelberg 2001作者: bonnet 時間: 2025-3-22 05:47
Neurodegenerative Disorders: Loss of Function Through Gain of Function978-3-662-04399-8Series ISSN 0945-6066 Series E-ISSN 2196-310X 作者: progestin 時間: 2025-3-22 11:01 作者: 描述 時間: 2025-3-22 13:25
Mechanisms of Motor Neuron Death in ALS,e most common form of adult motor neuron disease in humans, ALS typically initiates in middle to late life, leading to paralysis and death within three to five years. The disease usually begins asymmetrically in one limb, most commonly the leg, and then appears to spread to involve contiguous groups作者: Collar 時間: 2025-3-22 17:23 作者: 甜食 時間: 2025-3-22 21:15 作者: cravat 時間: 2025-3-23 03:07
The Value of Transgenic Models for the Study of Neurodegenerative Diseases,d, chronic illnesses that are among the most challenging and devastating diseases in medicine (Becker et al. 1998; Burright et al. 1995; Cleveland 1999; Davies et al. 1997; Goedert et al. 1998; Hardy and Gwinn-Hardy 1998; Lin et al. 1999; Mangiarini et al. 1996; Price et al. 1998b; Robitaille et al.作者: Projection 時間: 2025-3-23 07:34
Pathogenesis and Mechanism of Cerebral Amyloidosis in APP Transgenic Mice,ellular deposition of amyloid in plaques and vessels. In an effort to study the impact of cerebral amyloidosis on neurodegeneration, we have shown that amyloid plaque formation in APP transgenic mice is accompanied by region-specific neuron loss, synaptic changes, alterations in the cholinergic syst作者: 厚顏 時間: 2025-3-23 13:04 作者: 北極人 時間: 2025-3-23 16:19
The NEXT Step in Notch Processing and its Relevance to Amyloid Precursor Protein,signals governing their transport and localization in the cell. It is only fitting that, at the close of the millennium, the confluence of several unrelated fields resulted in the emergence of a new paradigm for signal transduction: .egulated .ntramembranous .roteolysis (RIP: Brown et al. 2000) of “作者: 暴發(fā)戶 時間: 2025-3-23 20:45
The Putative Role of Presenilins in the Transmembrane Domain Cleavage of Amyloid Precursor Protein n (Levy-Lahad et al. 1995; Rogaev et al. 1995; Sherrington et al. 1995). Although the exact pathogenic mechanism underlying the disease process remains to be further elucidated, it is fairly established that almost all PS missense mutations affect the processing of the amyloid precursor protein (APP作者: Fermentation 時間: 2025-3-23 23:25 作者: Toxoid-Vaccines 時間: 2025-3-24 04:26 作者: Lyme-disease 時間: 2025-3-24 08:41 作者: ENDOW 時間: 2025-3-24 12:25
,A Gain of Function of the Huntington’s Disease and Amyotrophic Lateral Sclerosis-Associated Genetice (HD), the genetic defect is a CAG repeat expansion in a gene that encodes the protein huntingtin, whose function is unknown. Several lines of evidence have demonstrated that the HD mutation is associated with abnormalities in bioenergetics, both in lymphoblasts of patients as well as in postmortem作者: homocysteine 時間: 2025-3-24 15:47 作者: 火光在搖曳 時間: 2025-3-24 20:46 作者: 去掉 時間: 2025-3-24 23:26 作者: 橢圓 時間: 2025-3-25 07:10
A. Lunkes,G. Yvert,Y. Trottier,D. Devys,J. L. Mandelations of biosignals. Although the material has been written and developed primarily for advanced undergraduate biomedical engineering students it will also be of interest to engineers and interested biomedical professionals of any discipline seeking an introduction to the field. Within education, m作者: 誘騙 時間: 2025-3-25 10:58 作者: HAWK 時間: 2025-3-25 13:27
D. L. Price,P. C. Wong,A. L. Markowska,G. Thinakaran,M. K. Lee,L. J. Martin,J. Rothstein,S. S. Sisodations of biosignals. Although the material has been written and developed primarily for advanced undergraduate biomedical engineering students it will also be of interest to engineers and interested biomedical professionals of any discipline seeking an introduction to the field. Within education, m作者: Plaque 時間: 2025-3-25 18:39 作者: 易達(dá)到 時間: 2025-3-25 22:20 作者: DAFT 時間: 2025-3-26 02:38
R. Kopan,S. Huppert,J. S. Mumm,M. T. Saxena,E. H. Schroeter,W. J. Ray,A. Goatethe most natural form of communication between humans, speech is a subject which has attracted much interest and attention over many years. The structure of speech, its production and perception mechanisms have long occupied linguists, psychologists and physiologists. Scientists and engineers have e作者: 幸福愉悅感 時間: 2025-3-26 05:00 作者: 愛社交 時間: 2025-3-26 08:47 作者: PUT 時間: 2025-3-26 15:50
B. Allinquant,G. Mainguy,A. Prochiantzhreads and, because of this, advances in one discipline may be transmitted to others. Presentation of recent results obtained in different disciplines encourages this interchange for the advancement of FGIT as a whole. Of particular interest are hybrid solutions that c- bine ideas taken from multipl作者: 傻 時間: 2025-3-26 17:09 作者: convert 時間: 2025-3-26 22:38 作者: 行業(yè) 時間: 2025-3-27 03:38 作者: 虛度 時間: 2025-3-27 09:14 作者: Firefly 時間: 2025-3-27 12:01
0945-6066 position of these aggregating proteins. The book provides insights into the cellular and animal models of these diseases, and how the molecular basis of neurodegeneration has become the preferred target of therapy.978-3-642-07448-6978-3-662-04399-8Series ISSN 0945-6066 Series E-ISSN 2196-310X 作者: 注意到 時間: 2025-3-27 15:46 作者: patriarch 時間: 2025-3-27 20:36 作者: 不確定 時間: 2025-3-27 22:19 作者: metropolitan 時間: 2025-3-28 05:19 作者: Obstruction 時間: 2025-3-28 08:19
T. L. Williamson,D. W. Cleveland to help the reader understand the time and frequency domain processes which may be used and to evaluate random physiological signals. A secondary goal is to learn the evaluation of actual mammalian data without spending most the time writing software programs. This publication utilizes “DADiSP”, a 作者: 猛烈責(zé)罵 時間: 2025-3-28 12:01 作者: Boycott 時間: 2025-3-28 17:42
D. L. Price,P. C. Wong,A. L. Markowska,G. Thinakaran,M. K. Lee,L. J. Martin,J. Rothstein,S. S. Sisod to help the reader understand the time and frequency domain processes which may be used and to evaluate random physiological signals. A secondary goal is to learn the evaluation of actual mammalian data without spending most the time writing software programs. This publication utilizes “DADiSP”, a 作者: 航海太平洋 時間: 2025-3-28 22:14 作者: 你正派 時間: 2025-3-28 23:05
K. Beyreuther,C. L. Masters to help the reader understand the time and frequency domain processes which may be used and to evaluate random physiological signals. A secondary goal is to learn the evaluation of actual mammalian data without spending most the time writing software programs. This publication utilizes “DADiSP”, a 作者: 來這真柔軟 時間: 2025-3-29 06:09 作者: 小步走路 時間: 2025-3-29 08:04
B. De Strooper,A. Herreman,P. Cupers,K. Craessaerts,L. Serneels,W. Annaerts spoken in isolation from a small vocabulary. Their performance degrades quite significantly, however, when they are required to cope with large vocabularies, continuous speech input and a wide variety of speakers. Nevertheless, the performance of both speech recognition and synthesis systems is im作者: 友好關(guān)系 時間: 2025-3-29 14:20
J. Herz,U. Beffert,T. Hiesberger,M. Gotthardtithm of the Fourier transform of the image function for getting the magnitude of the image and then take the imaginary part of Fourier transform of the image function for getting the phase of the image. After getting the phase of the image, take the inverse function of the same and then only we will作者: Antagonist 時間: 2025-3-29 16:07 作者: Tidious 時間: 2025-3-29 22:44 作者: 失望昨天 時間: 2025-3-30 00:36 作者: licence 時間: 2025-3-30 06:29
siderable interest to both graduate students and researchers working to develop personalized healthcare applications, as well as physiological sensor software and hardware developers..978-3-319-68414-7978-3-319-68415-4Series ISSN 2193-097X Series E-ISSN 2193-0988 作者: 過時 時間: 2025-3-30 11:15
Mechanisms of Motor Neuron Death in ALS,) and apparent fragmentation of the Golgi (Gonatas et al. 1992). A landmark discovery in deciphering the mechanism of the disease came from the identification of the mutations in the gene encoding cytoplasmic superoxide dismutase (SOD1) that underlie about 20% of the instances of inherited disease (作者: Dissonance 時間: 2025-3-30 14:38 作者: Coeval 時間: 2025-3-30 17:29 作者: Largess 時間: 2025-3-30 21:34 作者: Pathogen 時間: 2025-3-31 04:13
,Alzheimer’s Disease: Physiological and Pathogenetic Role of the Amyloid Precursor Protein (APP), itrted vesicles..In neurons, metabolism of APP releasing the Aβ peptide was found to occur at all sorting stations, such as at the ER/cisGolgi and TGN/endosomes producing intracellular Aβ peptide as well as at the cell surface leading to secretory Aβ peptide. Regarding the Aβ species generated in the 作者: probate 時間: 2025-3-31 06:37 作者: FLAGR 時間: 2025-3-31 10:27 作者: 難解 時間: 2025-3-31 13:59
,ApoE Receptors in the Brain: Novel Signaling Pathways with Potential Relevance for Alzheimer’s Dised to the cytoplasmic tail of APP by the adaptor protein FE65. This two-point interaction suggests that LRP may affect the subcellular localization, routing, and possibly processing of APP. Recently, we also described a novel signaling pathway by which two other members of the family, the VLDL recept
